Any optically active N-acylglutamic acid having L-configuration.
| Member | Definition | Role |
|---|
| 10-propargyl-10-deazaaminopterin | A pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. | pralatrexate |
| beta-citrylglutamic acid | An N-acyl-L-glutamic acid in which the acyl group is specified as beta-citryl. | beta-citrylglutamic acid |
| carglumic acid | A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. | carglumic acid |
| cb 3717 | | CB3717 |
| n-acetylglutamic acid | An N-acyl-L-amino acid that is L-glutamic acid in which one of the amine hydrogens is substituted by an acetyl group. | N-acetyl-L-glutamic acid |
| pemetrexed | An N-acylglutamic acid in which the N-acyl group is specified as 4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). | pemetrexed |