Page last updated: 2024-08-05 13:17:27

hydroxy seco-steroid

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ChEBI ID: 36853

Members (7)

MemberDefinitionRole
1,23,25-trihydroxyvitamin d3A hydroxycalciol that consists of vitamin D3 (calciol) bearing additional hydroxy substituents at positions 1, 23 and 25 (with 1alpha,23S-configuration). An intermediate in the degradation pathway of 1alpha,25-(OH)2D3.1alpha,23(S),25-trihydroxyvitamin D3
calcipotrieneA seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.calcipotriol
cholecalciferolA hydroxy seco-steroid that is (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene in which the pro-S hydrogen at position 3 has been replaced by a hydroxy group. It is the inactive form of vitamin D3, being hydroxylated in the liver to calcidiol (25-hydroxyvitamin D3), which is then further hydroxylated in the kidney to give calcitriol (1,25-dihydroxyvitamin D3), the active hormone.calciol
mogrolA tetracyclic triterpenoid that is cucurbitadienol in which the side-chain double bond (position 24-25) has undergone formal oxidation to introduce hydroxy groups at positions 24 and 25 (the 24R stereoisomer). It is a biometabolite of mogrosides found in Siraitia grosvenorii.mogrol
paricalcitolparicalcitol
previtamin d(3)A hydroxy seco-steroid which is an intermediate in the production of vitamin D3 in human skin.previtamin D3
vitamin d 2A vitamin D supplement and has been isolated from alfalfa.vitamin D2

Research

Studies (10,313)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,463 (33.58)18.7374
1990's1,023 (9.92)18.2507
2000's1,517 (14.71)29.6817
2010's3,173 (30.77)24.3611
2020's1,137 (11.02)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,836 (15.22%)5.53%
Reviews1,217 (10.09%)6.00%
Case Studies488 (4.04%)4.05%
Observational68 (0.56%)0.25%
Other8,457 (70.09%)84.16%