| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| Transient receptor potential cation channel subfamily A member 1 | 0 | 0 | 1 | 1 |
| interleukin 8 | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| AR protein | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 1 | 0 | 0 | 1 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| dual specificity protein phosphatase 3 | 0 | 1 | 0 | 1 |
| low molecular weight phosphotyrosine protein phosphatase isoform c | 0 | 1 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| tyrosine-protein phosphatase non-receptor type 22 isoform 1 | 0 | 1 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 1 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Estrogen receptor | 0 | 0 | 1 | 1 |
| Beta-hexosaminidase subunit alpha | 0 | 1 | 0 | 2 |
| Beta-hexosaminidase subunit beta | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 2 | 1 | 4 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Substance-K receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Low molecular weight phosphotyrosine protein phosphatase | 0 | 1 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Pteridine reductase 1 | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
| Trace amine-associated receptor 5 | 0 | 0 | 1 | 1 |
| Estrogen receptor beta | 0 | 0 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 2 | 0 | 2 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | 0 | 1 | 0 | 1 |
| estrogen receptor beta isoform 1 | 0 | 1 | 0 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 1 | 0 | 1 |
| tyrosine-protein phosphatase non-receptor type 7 isoform 2 | 0 | 1 | 0 | 1 |
| Dihydroxyacetone phosphate acyltransferase | 0 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S7 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L15 | 0 | 1 | 0 | 1 |
| Tetracycline resistance protein, class B | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| 72 kDa type IV collagenase | 0 | 1 | 0 | 1 |
| Stromelysin-1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L10 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L11 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L7/L12 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L19 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L20 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L27 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L28 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L29 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L31 type B | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L32 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L33 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L34 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L35 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S10 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S11 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S12 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S13 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S16 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S18 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S19 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S20 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S2 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S3 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S4 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S5 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S8 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S9 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L13 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L14 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L16 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L23 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S15 | 0 | 1 | 0 | 1 |
| Multidrug transporter MdfA | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L17 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L30 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L6 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S14 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S17 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L18 | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Neutrophil collagenase | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Collagenase 3 | 0 | 1 | 0 | 1 |
| Cannabinoid receptor 1 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L2 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L3 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L24 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L4 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L22 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L5 | 0 | 1 | 0 | 1 |
| 30S ribosomal protein S21 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L25 | 0 | 1 | 0 | 1 |
| 50S ribosomal protein L36 2 | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 8 | 0 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 12 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 11 | 0 | 0 | 0 | 1 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |