Page last updated: 2024-08-05 11:02:46

bipyridines

Compounds containing a bipyridine group.

ChEBI ID: 50511

Members (23)

MemberDefinitionRole
2-(3-carboxy-2-pyridinyl)-3-pyridinecarboxylic acid2-(3-carboxy-2-pyridinyl)-3-pyridinecarboxylic acid
2-[(3,4-dichlorophenyl)methylthio]-6-(3-pyridinyl)-3-pyridinecarbonitrile2-[(3,4-dichlorophenyl)methylthio]-6-(3-pyridinyl)-3-pyridinecarbonitrile
2-amino-4-(2-fluorophenyl)-6-(3-pyridinyl)-3-pyridinecarbonitrile2-amino-4-(2-fluorophenyl)-6-(3-pyridinyl)-3-pyridinecarbonitrile
2-amino-4-(2-furanyl)-6-(2-pyridinyl)-3-pyridinecarbonitrile2-amino-4-(2-furanyl)-6-(2-pyridinyl)-3-pyridinecarbonitrile
2-amino-4-pyridin-4-yl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile2-amino-4-pyridin-4-yl-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine-3-carbonitrile
2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
4-[[3-cyano-4-methyl-6-(3-pyridinyl)-2-pyridinyl]thio]-3-oxobutanoic acid ethyl ester4-[[3-cyano-4-methyl-6-(3-pyridinyl)-2-pyridinyl]thio]-3-oxobutanoic acid ethyl ester
4-pyridin-4-yl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile4-pyridin-4-yl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile
5,5'-dimethyl-2,2'-bipyridylAbametapir
abt 7025-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-4-pyrido[2,3-d]pyrimidinamine
amrinoneA 3,4'-bipyridine substituted at positions 5 and 6 by an amino group and a keto function respectively. A pyridine phosphodiesterase 3 inhibitor, it is a drug that may improve the prognosis in patients with congestive heart failure.amrinone
anabasamine5-(1-methyl-2-piperidinyl)-2-(3-pyridinyl)pyridine
anabaseineAnabaseine
anatabineAnatabine
benzyl viologenBenzyl viologen
cerulomycinA pyridine alkaloid that is 2,2'-bipyridine substituted by a methoxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity.caerulomycin A
lgk974A carboxamide, the structure of which is that of acetamide substituted on carbon by a 2',3-dimethyl-2,4'-bipyridin-5-yl group and on nitrogen by a 5-(pyrazin-2-yl)pyridin-2-yl group. It is a highly potent, selective and orally bioavailable Porcupine inhibitor (a Wnt signalling inhibitor).LGK974
LSM-16285LSM-16285
milrinoneA member of the class of bipyridines that is 2-pyridone which is substituted at positions 3, 5, and 6 by cyano, pyrid-4-yl, and methyl groups, respectively. It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure.milrinone
mk 0663A member of the class of bipyridines that is 2,3'-bipyridine which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively.etoricoxib
olprinoneolprinone
orellanineOrellanine
perampanelA member of the class of bipyridines that is 2,3'-bipyridin-6'-one substituted at positions 1' and 5' by phenyl and 2-cyanophenyl groups respectively. Used as an adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy.perampanel

Research

Studies (3,628)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990595 (16.40)18.7374
1990's710 (19.57)18.2507
2000's797 (21.97)29.6817
2010's1,012 (27.89)24.3611
2020's514 (14.17)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials593 (14.51%)5.53%
Reviews395 (9.66%)6.00%
Case Studies290 (7.09%)4.05%
Observational74 (1.81%)0.25%
Other2,736 (66.93%)84.16%