A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Reference |
|---|
| "Epilepsy is a common disorder affecting approximately one in every two hundred people, from all walks of life, and presenting in addition to the seizure disorder itself, varying social, psychological and economic problems." | ( Gilligan, B, 1976) |
| "Epilepsy is a chronic disease that requires long term therapy, and most of the established antiepileptic drugs (the exception is phenobarbital) must be administered several times daily." | ( Bialer, M, 1992) |
| "Pregnant women with epilepsy are at increased risk of seizures and complications." | ( Yerby, MS, 1992) |
| "Epilepsy is a state of neuronal hyperactivity which may be caused by an altered relationship between inhibitory and excitatory influences on neurons." | ( Craig, CR; Fleming, WW; Gould, EM; Taylor, DA, 1991) |
| "The grave course of epilepsy is associated with a decrease of the LCBF on the side of the focus." | ( Shestakov, VV; Shutov, AA, 1990) |
| "Primary reading epilepsy is a rare form of reflex epilepsy, in which reading is the specific stimulus evoking attacks." | ( Castro, LH; Grossmann, RM; Marques-Assis, L; Yacubian, EM, 1990) |
| "Recently epilepsy is analysed on terms of two different conditions, seizure susceptibility and seizure induction." | ( Eguchi, T; Enoki, Y; Hirabayashi, H; Nakase, H; Sakaki, T; Tada, T, 1990) |
| "Epilepsy is the most common presentation, but it has many other variable forms of neurological manifestations." | ( Collignon, PJ; Crimmins, D; Danta, G; Dwyer, D, 1990) |
| "Epilepsy is not a benign condition." | ( Treiman, DM, 1989) |
| "Epilepsy is an ancient disorder which treatment over the centuries has been guided by preconceptions regarding its origin." | ( van Gelder, NM, 1987) |
| "Eating epilepsy is predominantly a disorder of young adults, and the triggering mechanisms are extremely complex and elaborate." | ( Ahuja, GK; Behari, M; Pauranik, A; Prasad, K, 1988) |
| "Whether epilepsy is the result of oxygen deficiency alone or is due to the combined effect of hypoxia and ischemia is not known." | ( Albala, BJ; Moshé, SL, 1985) |
| "Only when the epilepsy is uncontrolled despite high plasma concentrations which cannot be raised because of side effects, a second drug should be given." | ( Schmidt, D, 1983) |
| "Since epilepsy is a long-standing condition lasting for years to decades, short-spanned cross-sectional observations are often misleading." | ( Kakegawa, N; Seino, M, 1982) |
| ""Old" cases of epilepsy are significantly more resistant to clonazepam medication." | ( Bacia, T; Okuszko, S; Purska-Rowińska, E, 1980) |
| "Reading epilepsy is rare." | ( Miyamoto, A; Oki, J; Takahashi, S; Tokumitsu, A, 1995) |
| "Temporal lobe epilepsy is associated with neuronal death, gliosis and sprouting of mossy fibres in the hippocampus of human and rats." | ( Ben-Ari, Y; Faissner, A; Jorquera, I; Niquet, J; Represa, A, 1995) |
| "Epilepsy is one of the most common neurological disorders." | ( Patsalos, PN; Sander, JW, 1994) |
| "Epilepsy is a major cause of morbidity and accounted for up to 40% of psychiatric outpatient attendances in the experience of the author in Transkei, South Africa." | ( Ovuga, EB, 1994) |
| "Once epilepsy is diagnosed, long-term treatment with AEDs is recommended, beginning with monotherapy." | ( Pellock, JM, 1994) |
| "Epilepsy is a disorder of the central nervous system in which the clinical symptoms are recurrent seizures." | ( Graves, NM; Leppik, IE, 1993) |
| "Epilepsy is the most common neurological disease of females in reproductive age." | ( Leppert, D; Wieser, HG, 1993) |
| "Epilepsy is the most common neurological disease of women of reproductive age." | ( Leppert, D; Wieser, HG, 1993) |
| "Epilepsy is by far the most prevalent serious neurologic condition." | ( Shorvon, SD, 1996) |
| "Epilepsy is common in individuals who are mentally retarded and/or otherwise multiply handicapped." | ( Mattson, RH, 1996) |
| "Epilepsy is a common condition with a prevalence of just 1% in a given population." | ( Korczyn, AD; Neufeld, MY, 1996) |
| "Epilepsy is a common condition in people with learning disabilities with many patients continuing to suffer from seizures despite antiepileptic drug (AED) treatment." | ( Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA, 1997) |
| "The results suggest epilepsy is highly prevalent in this population of children and that further research is needed into its cause." | ( Bhakta, P; Hackett, L; Hackett, RJ, 1997) |
| "Epilepsy is a relatively common problem in children, adults and the elderly." | ( Haller, JS; Kennedy, BT, 1998) |
| "Epilepsy is a common and often neglected illness in developing countries requiring a conscious effort by health workers, especially at community level, to enhance access to regular treatment and to motivate patients to continue treatment." | ( Kok, P, 1998) |
| "Chronic epilepsy is associated with increased excitability which may result from abnormal glutamatergic synaptic transmission involving altered properties of N-methyl-D-aspartate (NMDA) receptors." | ( Ben-Ari, Y; Khrestchatisky, M; Rafiki, A; Represa, A, 1998) |
| "Epilepsy is the most important neurological problem in developing countries, with a total of 50 million people worldwide having the condition." | ( Das, T; Pal, DK; Sengupta, S, 1998) |
| "Digestive epilepsy is a rare disease, poorly recognized by gastroenterologists." | ( Mendler, MH; Pillegand, B; Ravon, R; Sautereau, D, 1998) |
| "Epilepsy is a disorder of recurrent seizures that are neural in origin." | ( March, PA, 1998) |
| "Idiopathic epilepsy is one of the most common and treatable neurologic diseases of small animals." | ( Knowles, K, 1998) |
| "Epilepsy is a common neurologic condition in women of reproductive age." | ( Zahn, C, 1998) |
| "Epilepsy is a common disorder, the prevalence of which is estimated at between 0." | ( Champagne, F; Contandriopoulos, AP; Kennedy, W; Reinharz, D; Tessier, G, 1995) |
| "Hot water epilepsy is a benign epilepsy." | ( Badinant-Hubert, N; Cheliout-Heraut, F; Fohlen, M; Ioos, C; Jalin, C; Pinard, JM; Villeneuve, N, 1999) |
| "Reading epilepsy is an uncommon epileptic syndrome preferentially related to the temporoparietal region of the language dominant hemisphere." | ( Aras, G; Ibis, E; Küçük, NO; Mutluer, N; Sener, HO; Yiğit, A, 1999) |
| "Epilepsy is a complex, common disorder with severe consequences for patients." | ( Bjork, R; Cooper, JL; Dasheiff, RM; Dick, MT; Glaze, D; Haffar, AY; Johnson, L; Kerasidis, H; Luzecky, MH; Murthy, K; Santiago, A; Stergis, G; Thompson, JM, 1999) |
| "Since epilepsy is assumed to be a disease syndrome which is probably manifested by abnormal expression of multifocal genes, determination of the role of each chromosomal locus in the provocation of seizure activity is important." | ( Jin, W; Kajiwara, K; Maruyama, C; Naramoto, F; Ohguchi, H; Sugaya, A; Sugaya, E; Tsuda, T; Wakana, S; Yokote, N, 2000) |
| "The course of epilepsy is more difficult to predict, but failure to respond to the first AED is worrisome." | ( Datta, AN; Wirrell, EC, 2000) |
| "Limbic epilepsy is a chronic condition associated with a broad zone of seizure onset and pathology." | ( Bertram, EH; Mangan, PS; Scott, CA; Williamson, JM, 2000) |
| "Although epilepsy is fundamentally a circuit phenomenon, the most basic manifestation of the hyperexcitability characteristic of epilepsy must be evident at the level of a single neuron." | ( Coulter, DA, 2001) |
| "Cost of epilepsy care has escalated many folds in the recent past." | ( Thomas, SV, 2000) |
| "Epilepsy is the most common serious neurological disorder and is one of the world's most prevalent noncommunicable diseases." | ( Lhatoo, SD; Sander, JW; Scott, RA, 2001) |
| "Epilepsy is a common neurologic condition." | ( Huff, NA; Kalis, MM, 2001) |
| "Catamenial epilepsy is a condition characterized by an increase in seizures during particular phases of the menstrual cycle." | ( Foldvary, N; Lee, J; Lim, LL; Mascha, E, 2001) |
| "Epilepsy is associated with excess mortality of two to three times in developed countries." | ( Reghunath, B; Sankara Sarma, P; Thomas, SV, 2001) |
| "Epilepsy care in developing countries is lagging behind than in the developed countries." | ( Alexander, M; Pandit, L; Sarma, PS; Shekhar, L; Thomas, SV; Trivedi, C; Vengamma, B, 2001) |
| "The services for epilepsy are urban-based and there is underutilization of services, general practitioners and specialists." | ( Alexander, M; Pandit, L; Sarma, PS; Shekhar, L; Thomas, SV; Trivedi, C; Vengamma, B, 2001) |
| "Epilepsy is a major public health threat in the developing world, with much higher prevalence and incidence rates than those observed in developed countries." | ( Cohen, H; Snyder, PJ, 2001) |
| "Epilepsy is one of the most prevalent neurologic disorders and affects approximately 1% of the population." | ( Borbély, K, 2001) |
| "Epilepsy is a common neurologic disorder, and antiepileptic drugs (AEDs) are the mainstays of therapy." | ( Biederman, TS; McAuley, JW; Moore, JL; Smith, JC, 2002) |
| "Epilepsy is the most common neurological feature, occurring in 96% of patients." | ( Bombardieri, R; Curatolo, P; Verdecchia, M, 2002) |
| "Many forms of epilepsy are intractable to current therapies and there is a pressing need to develop agents and strategies to not only suppress seizures, but also cure epilepsy." | ( Jones, OT, 2002) |
| "Epilepsy is a public health problem in Africa due to prevalence and social exclusion." | ( Desplats, D; Doumbo, O; Farnarier, G; Nimaga, K, 2002) |
| "Hot water epilepsy is unique in South India and single solitary ring enhancing lesion in brain imaging is a common feature in Indian subcontinent." | ( Bhattacharya, S; Das, SK; Kundu, TN; Ray, BK; Saha, SP, 2002) |
| "Epilepsy is the most prevalent neurological disorder requiring long-term treatment and compliance." | ( Pandhi, P; Prabhakar, S; Tandon, M, 2002) |
| "Epilepsy is the main revealing symptom." | ( Andriamamonjy, C; Andriantsimahavandy, A; Rajaonarison, P; Ralamboson, S; Ramanampamonjy, R; Ramanantoanina, CE; Razafindratrimo, F; Villeneuve, R, 2001) |
| "Epilepsy is a common and heterogeneous neurological disorder arising from biochemical and molecular events that are incompletely understood." | ( Patel, MN, 2002) |
| "Epilepsy is a major symptom in succinic semialdehyde dehydrogenase deficiency." | ( Jaeken, J, 2002) |
| "Epilepsy is closely related to an altered transmission of GABA, the major inhibitory transmitter in the brain." | ( Bettler, B; Furtinger, S; Sperk, G, 2003) |
| "Epilepsy is a relatively common disease, afflicting 1%-2% of the population, yet many epileptic patients are not sufficiently helped by current pharmacological therapies." | ( Cvitanovic, P; Mogul, DJ; Slutzky, MW, 2003) |
| "Epilepsy is the most common neurologic disorder in young humans." | ( Bittigau, P; Ikonomidou, C; Sifringer, M, 2003) |
| "Epilepsy is a complex brain disorder involving excessive, synchronous, abnormal electrical firing patterns of neurons." | ( Greene, AE; Seyfried, TN; Todorova, MT, 2003) |
| "Most patients with epilepsy are started on one of the classic AEDs and, if it proves ineffective, another drug is tried, usually as monotherapy." | ( Ben-Menachem, E, 2003) |
| "Men with epilepsy are known to have reduced fertility." | ( Bjørnenak, T; Gjerstad, L; Haugen, TB; Røste, LS; Saetre, ER; Taubøll, E, 2003) |
| "Epilepsy is a chronic condition that has complex effects on social, vocational, and psychological function." | ( Gilliam, F; Hecimovic, H; Sheline, Y, 2003) |
| "Epilepsy is a significant health problem." | ( Koob, GF; Solbrig, MV, 2004) |
| "Epilepsy is a chronic disorder that adversely affects social, vocational, and psychological functioning." | ( Brown, K; Carter, J; Gilliam, FG; Hecimovic, H; Santos, J; Vahle, V, 2004) |
| "Seizures and epilepsy are clearly dependent on elevated intracellular calcium concentration ([Ca2+]i) by NMDA receptor activation and can be prevented by NMDA antagonists." | ( Kim, S; Rhim, H, 2004) |
| "Epilepsy is one of the most common but genetically complex neurological disorders in humans." | ( Ernest, S; Frankel, WN; Friedman, L; Gallaugher, L; Kitami, T; Nadeau, JH, 2004) |
| "Catamenial epilepsy is a menstrual cycle-related seizure disorder characterized by an increase in seizures at the time of menstruation." | ( Reddy, DS, 2004) |
| "Epilepsy is very common in tuberous sclerosis complex and occurs in 80 to 90% of affected individuals during their lifetime." | ( Thiele, EA, 2004) |
| "Catamenial epilepsy is a menstrual cycle-related seizure disorder that affects up to 70% of women with epilepsy." | ( Reddy, DS, 2004) |
| "Epilepsy is one of the commonest neurological conditions." | ( Leach, JP, 2004) |
| "Epilepsy is one of the most common neurological disorders." | ( Delorenzo, RJ; Deshpande, LS; Sun, DA, 2005) |
| "Epilepsy is often complicated by depression requiring antidepressant treatment." | ( Gerschlager, W; Langosch, JM; Münchau, A; Orth, M; Rothwell, JC; Trimble, MR, 2005) |
| "Drug design in epilepsy is now tackling a new target--epileptogenesis." | ( Lyon, AP; Marone, S; Wainman, D; Weaver, DF, 2005) |
| "Epilepsy is the most common primary neurological disorder known." | ( Sriram, D; Vaigundaragavendran, J; Yogeeswari, P, 2005) |
| "Epilepsy is a major public-health problem in Africa." | ( Gaulier, JM; Laroche, ML; Merle, L; Preux, PM; Traore, H; Viana, M, 2005) |
| "Women with epilepsy are more likely to have maternal and fetal complications during pregnancy." | ( Jeha, LE; Morris, HH, 2005) |
| "Epilepsy is a disease of recurrent seizures that can develop after a wide range of brain insults." | ( Ahmed, S; Asano, E; Beaumont, TL; Chugani, HT; Draghici, S; Krauss, R; Loeb, JA; Rakhade, SN; Shah, AK; Sood, S; Yao, B, 2005) |
| "Migraine and epilepsy are both chronic recurrent disorders with paroxysmal attacks." | ( Chen, SC, 2006) |
| "Epilepsy is a common and devastating neurological disorder." | ( Beck, H; Remy, S, 2006) |
| "Seizures and epilepsy are a common problem in childhood." | ( Mackay, M, 2005) |
| "The prevalence of epilepsy is high in many areas of Africa." | ( Diop, AG; Hauser, WA; Hesdorffer, DC; Logroscino, G, 2005) |
| "Epilepsy is a common neurologic disorder that manifests in diverse ways." | ( Stafstrom, CE, 2006) |
| "Epilepsy is a disorder characterized by recurrent seizures, which can increase the content of reactive oxygen in the brain." | ( Agar, E; Ayyildiz, M; Yildirim, M, 2006) |
| "Epilepsy is a common medical problem and many studies have demonstrated that infants of women with epilepsy (WWE) have a two to threefold higher risk of congenital malformations compared with the background population." | ( Chiarelli, F; Latini, G; Pelliccia, P; Tana, M; Verrotti, A, 2006) |
| "Epilepsy is a common clinical problem in patients with brain tumours, strongly affecting patients' quality of life." | ( Albani, F; Baruzzi, A; Carapella, CM; Dinapoli, L; Jandolo, B; Maschio, M; Occhipinti, E; Pace, A; Pompili, A; Zarabla, A, 2006) |
| "Epilepsy is a dynamic disease in which self-organization and emergent structures occur dynamically at multiple levels of neuronal integration." | ( Jung, KY; Kim, S; Lee, U, 2006) |
| "Epilepsy is a hetergenous syndrome characterized by recurrently and repeatedly occurring seizures." | ( Sasa, M, 2006) |
| "Epilepsy is one of the most common neurological disorders." | ( DeLorenzo, RJ; Deshpande, LS; Sun, DA, 2006) |
| "People with epilepsy are more likely to die prematurely than those without epilepsy." | ( Bell, GS; Sander, JW, 2006) |
| "Epilepsy is a neurological disorder consisting of recurrent seizures, resulting from excessive, uncontrolled electrical activity in the brain." | ( Boon, P; De Herdt, V; De Smedt, T; Dedeurwaerdere, S; Delbeke, J; Legros, B; Raedt, R; Van Hese, P; Van Laere, K; Vonck, K; Wadman, W; Waterschoot, L; Wyckhuys, T, 2006) |
| "Epilepsy is a major comorbid condition in adolescents with mental retardation and is often characterized by multiple seizure types that are refractory to treatment." | ( Hammer, AE; McKee, JR; Sunder, TR; Vuong, A, 2006) |
| "Epilepsy is quite common in autism spectrum disorders, and it is increasingly recognized as an additional clinical problem that must be dealt with." | ( Canitano, R, 2007) |
| "Epilepsy is an abnormal brain state in which a large population of neurons is synchronously active, causing an enormous increase in metabolic demand." | ( Ma, H; Schwartz, TH; Sharif, S; Suh, M; Zhao, M, 2006) |
| "Epilepsy is characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons." | ( Blair, RE; Carter, DS; DeLorenzo, RJ; Deshpande, LS; Haider, SN; Sombati, S, 2006) |
| "Epilepsy is an important problem in neurological disorders." | ( Bağirici, F; Bostanci, MO, 2007) |
| "Temporal lobe epilepsy is a common form of drug-resistant epilepsy that sometimes responds to dietary manipulation such as the 'ketogenic diet'." | ( Bergendahl, K; Daley, TJ; Garriga-Canut, M; Morrison, JF; Ockuly, J; Pfender, RM; Qazi, R; Roopra, A; Schoenike, B; Stafstrom, C; Sutula, T, 2006) |
| "Epilepsy is one of the most common presentations of patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS)." | ( Lin, CM; Thajeb, P, 2007) |
| "Epilepsy is one of the most frequent causes of neurological disorders in young adults." | ( da Nóbrega, AC; de Castro, RR, 2006) |
| "Epilepsy is a rare cause of sinus node dysfunction which should be recognised." | ( Aissi, K; Bagnères, D; Demoux, AL; Francès, Y; Granel, B; Mechulan, A; Rossi, P; Sbragia, P; Somma-Mauvais, H, 2007) |
| "Epilepsy is one of the most important features of the syndrome, in addition to the characteristic facial appearance, cardiac anomaly, dysphagia, deafness, mental retardation and growth delay." | ( Imai, K; Kagitani-Shimono, K; Kamio, N; Kurosawa, K; Nabatame, S; Nagai, T; Okinaga, T; Ozono, K, 2007) |
| "Temporal lobe epilepsy is one of the most common types of epilepsy." | ( Ayala-Guerrero, F; Campos-Sepúlveda, E; González-Maciel, A; Mexicano, G; Reynoso-Robles, R; Romero, RM, 2008) |
| "Epilepsy is characterized by neuronal hyperexcitability and hypersynchronization." | ( Chen, CR; Huang, ZL; Qiu, MH; Qu, WM; Urade, Y; Xu, XH; Yao, MH, 2007) |
| "Epilepsy is the most common neurological disorder, approximately 1% of the population worldwide have epilepsy." | ( Amado, D; Arida, RM; Cavalheiro, EA; Colugnati, DB; de Lima, E; Naffah-Mazzacoratti, Mda G; Scorza, FA, 2008) |
| "Epilepsy is one of the most common neurologic problems worldwide." | ( Chiarelli, F; De Simone, M; Latini, G; Manco, R; Verrotti, A, 2007) |
| "Epilepsy is the most common neurological disorder; approximately 1% of the population worldwide have epilepsy." | ( Arida, RM; Cavalheiro, EA; Colugnati, DB; Cravo, SL; de Almeida, AC; Schoorlemmer, GH; Scorza, FA, 2008) |
| "Epilepsy is a major public health problem in developing countries." | ( Ngoungou, EB; Preux, PM; Quet, F; Tran, DS, 2007) |
| "Epilepsy is a neurological disorder with a worldwide prevalence estimated to be 0." | ( Kulig, K; Malawska, B, 2008) |
| "Epilepsy is a major public health problem affecting nearly 50 million people world wide." | ( El Elshamy, KA; Elwakkad, AS; Sibaii, H, 2008) |
| "Epilepsy is an important component of ME." | ( Grover, WD; Hardison, HH; Hobdell, EF; Khurana, DS; Legido, A; Marks, HG; Melvin, JJ; Salganicoff, L; Valencia, I, 2008) |
| "Epilepsy is one of the most frequent disease in children, particularly in adolescents." | ( Chiarelli, F; Manco, R; Scardapane, A; Verrotti, A, 2008) |
| "Epilepsy is a serious neurological disorder in human beings and the long-term pathological events remain largely obscure." | ( Chen, LW; Huang, YG; Liu, YH; Wang, L, 2008) |
| "Epilepsy is a symptom of cerebral dysfunction, where there is a sudden and disorganised discharge of electrical activity from a group of neurones, producing symptoms that range from sensory absences to convulsive movements and unconsciousness." | ( Bryan, RA; Willmott, NS, 2008) |
| "Epilepsy is a major health problem worldwide, and neurocysticercosis (NCC) is one of the important causes of epilepsy in the tropics." | ( Gupta, RK; Nath, K; Pandey, CM; Pradhan, S; Prasad, A; Prasad, KN; Tripathi, M, 2009) |
| "Epilepsy is a multifaceted chronic disorder which has diverse and complex effects on the well-being of the patient." | ( Andelman, F; Auriel, E; Blatt, I; Chistik, V; Gandelman-Marton, R; Gross, B; Landov, H; Margolin, N; Neufeld, MY; Parmet, Y; Theitler, J, 2009) |
| "Epilepsy is a chronic disorder often requiring years of treatment." | ( Montouris, G; Sheth, RD, 2008) |
| "Epilepsy is a disease, closely connected with sex-hormones and can lead to adverse repercussion on the reproductive health." | ( Bozhinov, P; Bozhinova, S, 2005) |
| "Early epilepsy is known to worsen the developmental prognosis of young children with a congenital focal brain lesion, but its direct role is often very difficult to delineate from the other variables." | ( Deonna, T; Maeder-Ingvar, M; Mayor-Dubois, C; Roulet-Perez, E, 2008) |
| "Epilepsy is a serious neurological disorder with neuronal loss and spontaneous recurrent seizures, but the neurochemical basis remains largely unclear." | ( Chen, LW; Huang, YG; Liu, YH; Wang, L; Wei, LC, 2009) |
| "Single seizure and epilepsy is one of the most commonly encountered neurologic disorders in elderly individuals, arising as a result of complex and often multiple acquired underlying pathologies." | ( Alptekin, M; Erkutlu, I; Kurtul, N; Pençe, S; Tan, U, 2009) |
| "Epilepsy is the most common neurological presentation and seizures are often medically intractable." | ( Bauer, R; Dobesberger, J; Koppelstaetter, F; Kuchukhidze, G; Ortler, M; Trinka, E; Unterberger, I; Walser, G, 2009) |
| "Epilepsy is a syndrome of episodic brain dysfunction characterized by recurrent unpredictable, spontaneous seizures." | ( Abraham, PM; Krishnakumar, A; Paul, J; Paulose, CS, 2009) |
| "Pharmacotherapy for epilepsy is limited by high incidence of pharmacoresistance and failure to prevent development and progression of epilepsy." | ( Boison, D; Kaplan, DL; Li, T; Lusardi, TA; Pritchard, EM; Szybala, C; Wilz, A, 2009) |
| "Epilepsy is a considerable source of stigma and misery for sufferers in Nigeria." | ( Abadom, TR; Aguwa, EN; Ejim, EC; Ezeala-Adikaibe, B; Illo, CK; Ndukuba, K; Onodugo, OD; Onwuekwe, IO; Onyejizu, C, 2009) |
| "Epilepsy is one of the oldest neurological conditions known to humankind." | ( Nazıroglu, M, 2009) |
| "Epilepsy is the most common neurological disorder in both dogs and humans." | ( Arida, RM; Cavalheiro, EA; Cysneiros, RM; Ribeiro, MO; Scorza, CA; Scorza, FA; Terra, VC, 2009) |
| "Epilepsy is a prominent sign of neurological dysfunction in children with various fetal and maternal deficiencies." | ( Kim, MO; Naseer, MI; Shupeng, L, 2009) |
| "Epilepsy is often the most important clinical manifestation of the syndrome, even if its appearance is not constantly precocious." | ( Canevini, MP; Dalla Bernardina, B; Darra, F; Fiorini, E; La Selva, L; Lazzarotto, F; Piazzini, A; Vignoli, A; Zucca, C, 2009) |
| "Epilepsy is a chronic disorder affecting approximately 1% of the population of the world." | ( Lee, KK; Salamon, N, 2009) |
| "Epilepsy is a common seizure disorder affecting approximately 70 million people worldwide." | ( Boison, D; Stewart, KA, 2009) |
| "Seizures and epilepsy are associated with significant disability and substantial treatment costs, yet little is known about primary prevention." | ( Bromfield, EB; Dworetzky, BA; Kang, JH; Townsend, MK, 2010) |
| "The incidence of epilepsy is significantly higher in children than adults." | ( Holmes, GL, 2009) |
| "Epilepsy is a common neurological disorder which predominantly affects paediatric and young adolescent population." | ( Khan, MA; Koul, RK; Shah, PA; Shapoo, SF, 2009) |
| "Idiopathic epilepsy is the most common brain disease in dogs and also occurs in cats." | ( Thomas, WB, 2010) |
| "Epilepsy is neuronal disorder characterized by learning, cognitive and memory impairments." | ( Mathew, J; Nandhu, MS; Paul, J; Paulose, CS, 2010) |
| "Epilepsy is a neurological disorder, relatively common in the paediatric population." | ( Cheng, LS; Prasad, AN; Rieder, MJ, 2010) |
| "Posttraumatic epilepsy is a frequent consequence of brain trauma, but relatively little is known about how neuronal circuits are chronically altered after closed head injury." | ( Hunt, RF; Scheff, SW; Smith, BN, 2010) |
| "Epilepsy is defined as the tendency to spontaneous, excessive neuronal discharge, manifesting as seizures." | ( Marson, AG; Powell, G; Saunders, M, 2010) |
| "Hot water epilepsy is a benign reflex epilepsy." | ( Gokcil, Z; Hidir, UU; Ilker, IH; Ipekdal, HI; Odabasi, Z; Ulas, UH; Zeki, G; Zeki, O, 2010) |
| "Epilepsy is a major public health problem worldwide which is clinically characterized by recurrent seizures." | ( Brincat, M; Erel, CT; Gambacciani, M; Lambrinoudaki, I; Moen, MH; Rees, M; Rozenberg, S; Schenck-Gustafsson, K; Tremollieres, F; Vujovic, S, 2010) |
| "Epilepsy is a disease characterized by unprovoked epileptic seizures resulting from a bioelectrical brain dysfunction." | ( Diaz-Bustos, R; Mora-Puga, M; Palacios, GC; Ramirez-Campos, J; Sevilla-Castillo, RA, 2009) |
| "Epilepsy is associated with the presence of cataract." | ( Hanhart, J; Kaiserman, I; Levartovsky, S; Nemet, A; Vinker, S, 2010) |
| "Epilepsy is one of the most frequent neurological diseases in the pediatric population." | ( Amine, M; Bourrous, M; Bouskraoui, M; Draiss, G; Elibrahimi, I; Safini, F, 2010) |
| "Pediatric epilepsy is a common, chronic, and challenging physical illness for children and their families." | ( Bujoreanu, IS; DeMaso, DR; Ibeziako, P, 2010) |
| "Epilepsy is a neurological disorder primarily characterized by recurrent, unprovoked seizures resulting from excessive or synchronous neuronal activity in the brain." | ( Sajatovic, M; Syed, TU, 2010) |
| "Epilepsy is one of the most common neurological disorders, affecting up to 2% of the population worldwide." | ( Chung, SS, 2010) |
| "People with epilepsy are socially discriminated against on the grounds of widespread negative public attitudes, misunderstandings and defensive behaviour." | ( Ahmadi, K; Alen, YK; Anwar, M; Goh, GK; Hasan, SS; Wayne, WG, 2010) |
| "The term catamenial epilepsy is used to describe the cyclical occurrence of seizure exacerbations during particular phases of menstrual cycle in women with preexisting epilepsy." | ( Chiarelli, F; Coppola, G; Laus, M; Mohn, A; Parisi, P; Verrotti, A, 2010) |
| "The development of epilepsy is often associated with marked changes in central nervous system cell structure and function." | ( Cao, R; Cho, HY; Choi, YS; Dziema, H; Jung, YJ; Li, A; Obrietan, K, 2010) |
| "Epilepsy is a common disease of childhood, in which almost 25% of cases are resistant to common antiepileptic drugs." | ( Ghazavi, M; Ghofrani, M; Karimzadeh, P; Mahvelati, F; Tonekaboni, SH, 2010) |
| "Epilepsy is a major feature of Menkes disease, an X-linked recessive infantile neurodegenerative disorder caused by mutations in ATP7A, which produces a copper-transporting ATPase." | ( Donsante, A; Greenfield, JC; Hicks, JD; Kaler, SG; Liew, CJ; Sato, S, 2010) |
| "Epilepsy is associated with various reproductive disorders and some antiepileptic drugs also influence the steroid metabolism." | ( Dusková, M; Hill, M; Kancheva, R; Kubátová, J; Stárka, L; Vceláková, H; Vrbíková, J; Zárubová, J, 2010) |
| "Epilepsy is a common neurological condition characterized by unprovoked seizure attacks." | ( Chatterjee, A; Dutta, S; Gangopadhyay, PK; Ghosh, S; Rajamma, U; Sinha, S, 2011) |
| "Epilepsy is a condition characterized by signs and symptoms of neurological disorder." | ( Alexandre, V; Feletti, F; Girolineto, BM; Pereira, LR; Queiroz, RH; Sakamoto, AC, 2010) |
| "Epilepsy is a chronic condition characterized by recurrent unprovoked seizures." | ( Li, P; Liu, HJ; Wei, Q, 2010) |
| "The AAIR of epilepsy is comparable to that observed in developed countries, but AAMR is higher." | ( Banerjee, TK; Chaudhuri, A; Das, SK; Ghosal, MK; Hazra, A; Raut, DK; Ray, BK; Roy, T, 2010) |
| "New mothers with epilepsy are advised to breastfeed their children." | ( Deppe, C; Noachtar, S; Weil, S, 2010) |
| "Acquired epilepsy is associated with long-term neuronal plasticity changes in the hippocampus resulting in the expression of spontaneous recurrent seizures." | ( Carter, DS; DeLorenzo, RJ; Deshpande, LS; Rafiq, A; Sombati, S, 2011) |
| "Epilepsy is a chronic neurological disorder affecting 1% population worldwide." | ( Agarwal, NB; Agarwal, NK; Jain, S; Mediratta, PK; Sharma, KK, 2011) |
| "Epilepsy is a chronic neurological disorder characterized by spontaneous recurrent seizures, which also occur in demyelinating diseases of the central nervous system (CNS) with a higher prevalence." | ( Bai, H; Chen, LW; Gao, GD; Liu, B; Wang, C; You, Y; Zhang, H, 2011) |
| "Epilepsy is one of the most common neurologic problems worldwide." | ( Ataie, Z; Babri, Sh; Ebrahimi, H; Golzar, MG; Mohaddes, G, 2011) |
| "Epilepsy is a neurodegenerative disease with periodic occurrences of spontaneous seizures as the main symptom." | ( Baek, IJ; Lee, BJ; Lee, JG; Lee, TH; Nahm, SS; Nam, SY; Oh, KW; Yon, JM; Yun, YW, 2011) |
| "Epilepsy is a common neurological disorder, which is attributed to uncontrollable abnormal hyper-excitability of neurons." | ( Bystritsky, A; Chung, YA; Fischer, K; Jolesz, FA; Jung, KI; Maeng, LS; Min, BK; Park, SI; Yoo, SS; Zhang, Y, 2011) |
| "Epilepsy is a common clinical syndrome with recurrent neuronal discharges in cerebral cortex and hippocampus." | ( Hsieh, CL; Lin, YW, 2011) |
| "Epilepsy is one of the most impactful diseases on social life." | ( Errichiello, L; Striano, P; Striano, S; Zara, F, 2011) |
| "Epilepsy is a brain dysfunction characterised by unpredictable occurrence of seizures." | ( Bhattacharya, J; Mandal, SK; Roy, T; Sadhu, M, 2010) |
| "Epilepsy is one of the most common neurological disorders, affecting about 1% of the population worldwide." | ( Schulze-Bonhage, A, 2011) |
| "Although epilepsy is reported to be common among patients with ASA, very few long-term follow-up studies are available." | ( Barboni, C; Contri, M; Corbetta, C; Furlan, F; Gamba, A; Grioni, D; Lastrico, A; Marzocchi, GM; Parini, R; Vizziello, P, 2011) |
| "Startle epilepsy is a rare form of epilepsy with seizures triggered by unexpected stimuli." | ( Bargalló, N; Boget, T; Carreño, M; Donaire, A; Falcón, C; Fernández, S; Maestro, I; Rumià, J; Seres, E; Setoain, X, 2011) |
| "Epilepsy is detected in about 23% of patients with fragile X syndrome (FXS)." | ( Ferrando, T; Genovés, J; Martorell, L; Molero, M; Naudó, M; Poo, P; Tondo, M, 2011) |
| "Epilepsy is a neurological disorder associated with excitatory and inhibitory imbalance within the underlying neural network." | ( Doretto, MC; Drumond, LE; Guidine, PA; Kushmerick, C; Massensini, AR; Moraes, MF, 2011) |
| "Epilepsy is a major clinical feature of this disorder." | ( Levin, S; Prasad, AN; Prasad, C; Rupar, CA, 2011) |
| "Epilepsy is a chronic disorder that significantly affects learning and behavior." | ( Aneja, S; Kumar, V; Seth, A; Singh, H; Unni, KE, 2012) |
| "Epilepsy is a serious health disorder affecting both paediatric and adult population worldwide." | ( Klapková, E; Komárek, V; Tesfaye, H; Tesfayeová, A, 2011) |
| "Epilepsy is not a singular disease, but a variety of disorders." | ( Szupera, Z, 2011) |
| "Epilepsy is a chronic neurological disorder characterized by recurrent seizures, and is highly resistant to medication with up to 40% of patients continuing to experience seizures whilst taking oral antiepileptic drugs." | ( Campbell, TE; Cook, MJ; Halliday, AJ; McLean, KJ; Nelson, TS; Razal, JM; Wallace, GG, 2012) |
| "Epilepsy is a chronic neurological disorder and well documented to induce cognitive impairment." | ( Goel, RK; Mishra, A, 2012) |
| "Epilepsy is one of the most common serious neurological conditions worldwide, with an age-adjusted incidence of approximately 50 per 100,000 persons per year in developed countries." | ( Becerra, JL; Corredera, E; Ojeda, J; Ruiz Giménez, J, 2011) |
| "Epilepsy is suppressed by reducing the temperature to reduce the duration of this epileptic episode." | ( Chang, CW; Chiou, JC; Hou, KC; Huang, YH; Shaw, FZ, 2011) |
| "Epilepsy is a common and refractory neurological disorder, but the neuronal regulatory mechanisms of epileptogenesis remain largely unclear." | ( Hu, XL; Liu, YY; Mei, L; Tan, GH; Xiong, ZQ; Yin, DM, 2011) |
| "Epilepsy is characterized by recurrent seizures, which are caused by excessive discharges from cerebral neurons." | ( Araki, H; Kawasaki, H; Suemaru, K; Takechi, K, 2012) |
| "Epilepsy is a common (50 million patients worldwide) neurological disorder characterized by seizures that are caused by episodic abnormal electrical activity in the brain." | ( Gasior, M; Giardina, WJ, 2009) |
| "Catamenial epilepsy is caused by fluctuations in progesterone-derived GABA(A) receptor-modulating anticonvulsant neurosteroids, such as allopregnanolone, that play a significant role in the pathophysiology of epilepsy." | ( Gangisetty, O; Gould, J; Reddy, DS, 2012) |
| "Epilepsy is the third most common chronic neurological disorder." | ( Desantis, KA; Velíšková, J, 2013) |
| "Epilepsy is not considered a neurodegenerative disorder, but the hippocampus is severely affected in temporal lobe epilepsy." | ( Szot, P, 2012) |
| "Epilepsy is one of the most common chronic neurologic disorders." | ( Brigo, F; Del Felice, A, 2012) |
| "Epilepsy is a serious and common chronic neurological disease with an urgent need for novel treatment options, because 30% of all epilepsy patients do not respond to currently available drugs." | ( Lerche, H; Nies, AT; Orhan, G; Schwab, M; Wuttke, TV, 2012) |
| "Epilepsy is a common neurological disorder characterized by recurrent seizures often unresponsive to pharmacological treatment." | ( de Curtis, M; Librizzi, L; Noè, F; Ravizza, T; Vezzani, A, 2012) |
| "Epilepsy is characterised by the propensity of the brain to generate spontaneous recurrent bursts of excessive neuronal activity, seizures." | ( Kaila, K; Kullmann, DM; Miles, R; Pavlov, I, 2013) |
| "Epilepsy is a neurological disorder produced by an imbalance between excitatory and inhibitory neurotransmission, in which transporters of both glutamate and GABA have been implicated." | ( López-Pérez, SJ; Medina-Ceja, L; Morales-Villagrán, A; Sandoval-García, F, 2012) |
| "Epilepsy is treated with a variety of anticonvulsants that are often used concomitantly." | ( Božina, N; Božina, T; Granić, P; Hajnšek, S; Kuzman, MR; Lalić, Z; Lovrić, M; Sporiš, D, 2012) |
| "Epilepsy is very common in tuberous sclerosis and occurs in 75-92% of affected individuals during their life-time." | ( Belousova, ED; Dorofeeva, MIu, 2012) |
| "Epilepsy is a common neurological disorder characterized by an initial injury due to stroke, traumatic brain injury, brain infection, or febrile seizures causing status epilepticus (SE)." | ( Chanda, S; de Araujo Furtado, M; Rossetti, F; Yourick, D, 2012) |
| "Epilepsy is a recurrent chronic nervous system disease." | ( Gao, F; He, H; Jiang, W; Li, XW; Liu, YF; Ma, L; Meng, XD; Wei, D, 2012) |
| "Epilepsy is one of the main symptoms in GAMT and CT1 deficiency, whereas the occurrence of febrile convulsions in infancy is a relatively common presenting symptom in all the three above-mentioned diseases." | ( Battini, R; Cioni, G; Leuzzi, V; Mastrangelo, M, 2013) |
| "Children with epilepsy are at risk for behavioral and cognitive comorbidities." | ( Dunn, DW; Hummer, TA; McDonald, BC, 2013) |
| "Epilepsy is one of the most common neurological disorders, yet its treatment remains unsatisfactory." | ( Bao, Y; Hu, SJ; Li, HM; Xie, W; Xing, JL; Yu, YH, 2012) |
| "Post-traumatic epilepsy is prevalent, often difficult to manage, and currently cannot be prevented." | ( D'Ambrosio, R; Darvas, F; Eastman, CL; Farin, FM; Fender, JS; Miller, JW; Ojemann, J; Rothman, SM; Smyth, MD; Temkin, NR; Verley, DR; Wilkerson, HW, 2013) |
| "Epilepsy is a common manifestation of mitochondrial disease associated with mutations of the mitochondrial polymerase γ (POLG)." | ( Jääskeläinen, S; Majamaa, K; Martikainen, MH; Päivärinta, M, 2012) |
| "Epilepsy is characterized by recurrent spontaneous seizures due to hyperexcitability and hypersynchrony of brain neurons." | ( De Lanerolle, NC; Devinsky, O; Najjar, S; Rogawski, MA; Vezzani, A, 2013) |
| "Patients with epilepsy are at high risk for major depression relative to the general population, and both disorders are associated with changes in adult hippocampal neurogenesis, although the mechanisms underlying disease onset remain unknown." | ( Kajitani, K; Kamada, T; Katogi, A; Nakabeppu, Y; Nomaru, H; Ohnishi, YH; Ohnishi, YN; Sakumi, K; Shigeto, H; Takase, K; Yutsudo, N, 2013) |
| "Epilepsy is a complex neurological disorder characterized by unprovoked seizures." | ( Bassuk, AG; Mei, X; Slusarski, DC; Wu, S, 2013) |
| "Epilepsy is a major clinical and social issue in Africa." | ( Adjien, C; Avode, G; Druet-Cabanac, M; Glitho, G; Houinato, D; Preux, PM; Yemadje, LP, 2013) |
| "Epilepsy is a group of conditions characterized by sporadic occurrence of seizures and unconsciousness." | ( Binder, DK; Fiacco, TA; Hsu, MS; Hubbard, JA, 2013) |
| "Epilepsy is characterized by recurrent synchronizations of neuronal activity, which are both a cardinal clinical symptom and a debilitating phenomenon." | ( Cossart, R; Feldt Muldoon, S; Soltesz, I, 2013) |
| "Epilepsy is one of the most common neurological conditions in the elderly, and the incidence of de novo geriatric epilepsy is rising." | ( Lossius, MI; Markhus, R; Nakken, KO; Sætre, E, 2013) |
| "Epilepsy is a common neurological condition characterised by recurrent seizures." | ( Marson, AG; Milburn-McNulty, P; Powell, G; Sills, GJ, 2013) |
| "Early treatment of epilepsy is warranted to avoid possible severe consequences." | ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Epilepsy is a major manifestation of tuberous sclerosis complex (TSC)." | ( Agricola, K; Anderson, AE; Franz, DN; Holland-Bouley, K; Kim, MO; Krueger, DA; Lopez, CM; Mays, M; Tudor, C; Wilfong, AA, 2013) |
| "Epilepsy is a heterogeneous and chronic neurological condition of undefined etiology in the majority of cases." | ( Currie, RW; Esser, MJ; Galic, MA; Moriyama, C; Mychasiuk, R; Perrot, TS; Pittman, QJ, 2013) |
| "Epilepsy is a chronic brain disorder involving recurring seizures often precipitated by an earlier neuronal insult." | ( Chang, PK; Charron, F; Dezsi, G; Gill, R; Huang, TC; Jones, NC; Machnes, ZM; McKinney, RA; O'Brien, TJ; Ozturk, E; Reist, N; Szyf, M, 2013) |
| "Epilepsy is one of the most common neurological disorders prevalent in childhood period." | ( Bharti, B; Pandey, S; Singhi, P, 2014) |
| "Epilepsy is a common neurological disorder." | ( Loiacono, G; Rossi, A; Verrotti, A; Zaccara, G, 2014) |
| "Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, which may increase the content of reactive oxygen and nitrogen species." | ( Kir, HM; Kuskay, S; Musul, M; Oztaş, B; Sahin, D, 2013) |
| "Epilepsy is a debilitating disease affecting 1-2% of the world's population." | ( Bestman, JE; Chan, SS; Chou, CJ; Inks, ES; Josey, BJ; Rahn, JJ; Rogers, CE; Stackley, KD, 2014) |
| "Epilepsy is a serious neural disease that affects around 50 million people all over the world." | ( He, J; Li, BC; Li, P; Wan, JB; Wang, YT; Xiang, C; Zhu, HL, 2014) |
| "Epilepsy is a chronic neurologic disorder which often induces numerous adverse long-term neurologic effects, such as behavioral and cognitive deficits, increased predisposition to additional seizures, and cell injury or death." | ( Bhutada, PS; Patel, FR; Vimala, PV, 2014) |
| "Epilepsy is a common neurological disorder with seizures, but diagnostic approaches in veterinary clinics remain limited." | ( Hasegawa, T; Horitani, Y; Komori, M; Sumita, M; Takenaka, S; Tamai, R; Tanaka, K, 2014) |
| "If the diagnosis of epilepsy is established and epilepsy surgery is not appropriate, AED treatment should be optimized." | ( Ben-Menachem, E, 2014) |
| "Epilepsy is one of the most common neurological disorders." | ( de Biase, S; Gigli, GL; Merlino, G; Valente, M, 2014) |
| "Epilepsy is defined as the tendency to spontaneous, excessive neuronal discharge manifesting as seizures." | ( Marson, AG; Powell, G; Saunders, M, 2014) |
| "Epilepsy is one of the most common neurological diseases in the world." | ( Breborowicz, GH; Chuchracki, M; Florek, E; Hassan-Bartz, M; Krzyścin, M; Kulza, M; Miller, R; Napierała, M; Wachowiak, A; Wozniak, A, 2013) |
| "Epilepsy is the most commonly encountered serious neurological problem in obstetrical practice." | ( Ahmed, R; Apen, K; Endean, C, 2014) |
| "Epilepsy is a common neurological condition characterised by recurrent seizures." | ( Marson, AG; Milburn-McNulty, P; Powell, G; Sills, GJ, 2014) |
| "Epilepsy is a family of brain disorders with a largely unknown etiology and high percentage of pharmacoresistance." | ( DiNuzzo, M; Giove, F; Mangia, S; Maraviglia, B, 2015) |
| "Acquired epilepsy is frequently associated with structural lesions after trauma, stroke, and infections." | ( Bar-Klein, G; Cacheaux, LP; Cheng, P; Friedman, A; Heinemann, U; Kamintsky, L; Kaufer, D; Kim, SY; Prager, O; Schoknecht, K; Weissberg, I; Wood, L, 2014) |
| "Epilepsy is one of the most common neurological disorders, and approximately one-third of patients with epilepsy are resistant to anti-epileptic drugs (AEDs)." | ( Dang, J; Ding, DX; Huang, WJ; Liu, H; Song, MY; Tian, FF; Wang, YZ, 2014) |
| "Hot water epilepsy is rarely described in European countries, where bathing epilepsy in younger children is more common and often confused with this type of epilepsy." | ( Canevini, MP; Chiesa, V; La Briola, F; Peron, A; Savini, MN; Vignoli, A; Zambrelli, E, 2014) |
| "Intractable epilepsy is a challenging aspects of pediatric epilepsy." | ( Abdollahe-Gorgi, F; Azargashb, E; Beheshti, M; Ghofrani, M; Karimzadeh, P; Sedighi, M, 2014) |
| "Epilepsy is frequent during the evolution of mitochondrial disorders (30%) with different presentation in childhood and adulthood in term of type of epilepsy, of efficacy of treatment and also in term of prognosis." | ( Desguerre, I; Hully, M; Nabbout, R; Rio, M, 2014) |
| "Epilepsy is a heterogeneous family of neurological disorders that manifest as seizures, i." | ( DiNuzzo, M; Giove, F; Mangia, S; Maraviglia, B, 2014) |
| "Epilepsy is a common neurological disease." | ( Li, D; Pan, LP; Song, YJ; Tian, X; Wu, QJ; Xie, W, 2014) |
| "Epilepsy is an abnormal emergent property of disturbances in neuronal networks which, even for epilepsies characterized by focal seizures, involve widely distributed systems, often in both hemispheres." | ( Dedeurwaerdere, S; Engel, J; Federico, P; Shultz, SR, 2014) |
| "Although epilepsy is a common neurological disorder, its mechanism(s) are still not completely understood." | ( Chen, L; Chen, Y; Jiang, G; Li, J; Li, Z; Wang, X; Wang, Z, 2014) |
| "Epilepsy is one of the major neurological disorders still awaiting safer drugs with improved antiepileptic effect and lesser side effects." | ( Goel, RK; Mishra, A, 2014) |
| "Epilepsy is a disorder characterised by recurrent seizures and molecular events, including the activation of early expression genes and the post-translational modifications of functional proteins." | ( Beas-Zarate, C; Bitar-Alatorre, EW; Castaneda-Arellano, R; Feria-Velasco, AI; Rivera-Cervantes, MC, 2014) |
| "Epilepsy is the most common medical neurologic disease of dogs." | ( Patterson, EE, 2014) |
| "Children with epilepsy are more likely to have behavioral problems compared to children without epilepsy." | ( Aldenkamp, AP; de Louw, AJ; Halma, E; IJff, DM; Klinkenberg, S; Majoie, M, 2014) |
| "Epilepsy is a paroxysmal condition characterized by repeated transient seizures separated by longer interictal periods." | ( Blauwblomme, T; Huberfeld, G; Jiruska, P, 2014) |
| "Epilepsy is a complex disease necessitating continuous development of new therapeutic strategies to encounter drug-resistant cases." | ( Alsaad, AM; Koren, G, 2014) |
| "Epilepsy is a chronic disease that affects metabolism either alone or through the antiepileptic drug (AED) treatment." | ( Abdelaziz, GH; Ahmed, SM; El-Jaafary, SI; Kamel, T; Rabah, AM; Talaat, FM, 2015) |
| "Although idiopathic epilepsy is regarded as having a significantly lower risk factor of developing refractory epilepsy, still a subset of patients with idiopathic epilepsy might be refractory to medical treatment." | ( Chiang, CT; Lin, LC; Ouyang, CS; Wu, HC; Wu, RC; Yang, RC, 2014) |
| "Epilepsy is characterized by the abnormal activation of neurons in the cerebral cortex, but the molecular and cellular mechanisms contributing to the development of recurrent seizures are largely unknown." | ( Abe, Y; Gondo, A; Morita, A; Nuriya, M; Shinotsuka, T; Yasui, M, 2014) |
| "Epilepsy is defined as the tendency to spontaneous, excessive neuronal discharge manifesting as seizures." | ( Marson, AG; Powell, G; Rigby, A; Saunders, M, 2014) |
| "PCDH19-related epilepsy is an emerging epileptic syndrome characterized by the occurrence of epilepsy in female patients associated with mental retardation and autistic features in most cases." | ( Specchio, N; Trivisano, M; Vigevano, F, 2015) |
| "Epilepsy is the most common neurological symptom of tuberous sclerosis complex, occurring in 80% to 90% of affected individuals over the course of their lifetimes and causing significant morbidity and mortality." | ( Curatolo, P, 2015) |
| "Epilepsy is a chronic disorder of brain whose treatment consists of controlling seizures with antiepileptic drugs that very often related with side-effects which in rare circumstances can be potentially life-threatening." | ( Dhanda, A; Kamboj, VK; Ranjan, S; Verma, PK, 2015) |
| "Epilepsy is a major neurological disorder characterized by spontaneous seizures accompanied by neurophysiological changes." | ( Chang, SJ; Tsai, HL, 2015) |
| "Epilepsy is a disease of neuronal hyper-synchrony that can involve both neocortical and hippocampal brain regions." | ( Andrade, R; Loeb, JA; Serafini, R, 2015) |
| "The diagnosis of epilepsy is usually made by a neurologist but can be difficult to be made in the early stages." | ( Abdel-Aziz, K; Al-Jumeily, D; Fergus, P; Hignett, D; Hussain, A, 2015) |
| "Epilepsy is considered to be resolved for individuals past the applicable age of an age-dependent epilepsy syndrome or those who have remained seizure-free for the past 10 years, with no seizure medicines for the past 5 years." | ( Fisher, RS, 2015) |
| "Epilepsy is a common neurological disorder." | ( Li, M; Wang, S; Wang, X; Xu, X; Yang, X; Zhang, Y, 2015) |
| "Epilepsy is a frequent neurological disorder that affects directly 0." | ( Orbán-Kis, K; Szabadi, T; Szilágyi, T, 2015) |
| "Epilepsy is one of the commonest chronic neurological disorders in developing countries." | ( Gregoraszczuk, EL; Grzyb, E; Kwiecińska, P, 2014) |
| "Drug-resistant epilepsy is believed to be multifactorial involving both genetic and non-genetic factors." | ( Chinvarun, Y; Keangpraphun, T; Kijsanayotin, P; Towanabut, S, 2015) |
| "Epilepsy is a common neurological disease characterized by recurrent unprovoked seizures." | ( Baum, L; Cherny, SS; Gui, H; Haerian, BS; Kwan, P; Lim, KS; Mohamed, Z; Rafia, MH; Raymond, AA; Sha'ari, HM; Sham, PC; Tan, HJ, 2016) |
| "Epilepsy is a chronic brain disease characterised by recurrent seizures." | ( Hasegawa, M; Hongo, Y; Ikegaya, Y; Ogawa, K; Sakaguchi, G; Takasu, K, 2015) |
| "Temporal lobe epilepsy is often presented by medically intractable recurrent seizures due to dysfunction of temporal lobe structures, mostly the temporomesial structures." | ( Eslamizade, MJ; Ghadiri, T; Gorji, A; Hadjighassem, M; Modarres Mousavi, SM; Saffarzadeh, F, 2015) |
| "Epilepsy is broadly characterized by aberrant neuronal excitability." | ( Barker-Haliski, M; White, HS, 2015) |
| "Catamenial epilepsy is a periodic increase in seizure frequency in women with epilepsy during menstruation, or at any specific point in the menstrual cycle." | ( Chen, K; Liang, Y; Liu, J; Sun, H; Xie, Y; Yu, N, 2015) |
| "Catamenial epilepsy is a common phenomenon in female epileptic patients that is, in part, influenced by the 17-β-estradiol level during the menstrual cycle, which modulates the strength of the epileptic seizures." | ( Huang, Y; Liu, X; Wang, G; Wang, X; Wang, Y; Zhang, Y, 2015) |
| "Epilepsy is common in individuals with autism spectrum disorder (ASD) and intellectual disabilities (ID)." | ( Katz, N; Moses, L; Weizman, A, 2015) |
| "Untreated epilepsy is a major global public health problem with more than 20 million people not being treated for an easily treatable disease." | ( Patterson, V; Rajbhandari, H; Singh, M; Vishnubhatla, S, 2015) |
| "Background: Epilepsy is the most common neurological disease in children." | ( Chotipanich, C; Khongsaengdao, S; Khusiwilai, K; Paticheep, S; Wichaporn, A, 2015) |
| "Epilepsy is a neurological disorder that has been associated with oxidative stress therefore epilepsy models have been develop such as kainic acid and pentylenetetrazol are usually used to understanding of the molecular mechanisms of this disease." | ( Díaz-Ruíz, A; Flores-Espinosa, P; Heras-Romero, Y; Juárez-Rebollar, D; Manjarrez, J; Méndez-Armenta, M; Nava-Ruíz, C; Zaga-Clavellina, V, 2015) |
| "Epilepsy is one of the most common and severe neurologic diseases." | ( Chen, G; Chen, L; Deng, W; Jiang, G; Li, J; Mi, X; Wang, N; Wang, X; Wang, Z; Zhang, Y, 2016) |
| "Epilepsy is an independent prognostic factor for longer survival in glioblastoma patients." | ( Berendsen, S; Bours, V; Broekman, ML; Kauw, F; Kroonen, J; Poulet, C; Robe, PA; Seute, T; Snijders, TJ; Spliet, WG; Varkila, M; Willems, M, 2016) |
| "Epilepsy is a severe neurological disorder characterized by altered electrical activity in the brain." | ( Borges, K; Eloqayli, H; Hadera, MG; Jaradat, S; McDonald, T; Meisingset, TW; Smeland, OB; Sonnewald, U, 2016) |
| "Epilepsy is the commonest clinical presentation, though it may also present with headache, symptoms of raised intracranial tension, hydrocephalus and ocular symptoms depending upon the localisation of the parasitic cysts." | ( Mathew, A; Sharma, M; Singh, T, 2015) |
| "Epilepsy is one of the most common diseases affecting the nervous system, with more than 50 million patients suffering from epilepsy worldwide." | ( Lu, S; Wang, X, 2015) |
| "Epilepsy is a common neurological condition characterised by recurrent seizures." | ( Marson, AG; Milburn-McNulty, P; Powell, G; Sills, GJ, 2015) |
| "Epilepsy is a neurological disorder with an annual incidence in the Netherlands of 30 per 100,000 people." | ( Admiraal-van de Pas, Y; van Rooij, FJ, 2015) |
| "Treatment of canine epilepsy is problematic." | ( Berendt, M; Fredsø, N; Møller, A; Sabers, A; Toft, N, 2016) |
| "Autism and epilepsy are two associated disorders that are highly prevalent, share common developmental origins, and demonstrate substantial heritability." | ( Jacob, J, 2016) |
| "Epilepsy is now recognized as the second most common neurological disease in China." | ( Fang, X; Fu, X; Gong, G; Hu, X; Jiang, AO; Wei, C; Yang, X, 2015) |
| "Symptomatic epilepsy is a common complication of glioblastoma and requires pharmacotherapy." | ( Chinot, O; Cloughesy, T; Gilbert, MR; Gorlia, T; Happold, C; Hegi, M; Mehta, MP; Nabors, LB; Perry, JR; Pugh, SL; Reardon, DA; Roth, P; Stupp, R; Weller, M; Wick, W, 2016) |
| "Epilepsy is one of the most important neurological disorders with high prevalence worldwide." | ( Ayati, A; Emami, S; Foroumadi, A, 2016) |
| "Epilepsy is a prominent feature of TSC, with seizures often occurring after the diagnosis of TSC has already been made." | ( Jeong, A; Wong, M, 2016) |
| "Epilepsy is one of the most common neurological conditions, which affect nearly 1% of the entire population." | ( Agarwal, KK; Jha, P; Kumar, R; Sahoo, MK, 2016) |
| "Women with epilepsy are exposed to social stigma, and they have anxiety and lose self-confidence in their social role as a woman." | ( Honda, M; Watanabe, M, 2015) |
| "Epilepsy is a frequent comorbidity in patients with focal cortical dysplasia (FCD)." | ( Akamine, S; Hara, T; Ishizaki, Y; Matsushita, Y; Nakabeppu, Y; Nishio, M; Sakai, Y; Sanefuji, M; Shigeto, H; Shimmura, M; Suzuki, A; Takada, H; Torisu, H, 2016) |
| "Epilepsy is a neurological disorder which occurs due to excessive firing of excitatory neurons in specific region of brain and associated with cognitive impairment and depression." | ( Koshal, P; Kumar, P, 2016) |
| "Epilepsy is a common neurological disease characterized by periodic seizures." | ( Aghaei, Z; Haeri, NA; Palizvan, MR; Rafiei, M; Sadegh, M, 2016) |
| "Epilepsy is increasingly considered as the dysfunction of a pathologic neuronal network (epileptic network) rather than a single focal source." | ( Abela, E; Carmichael, DW; Centeno, M; Grouiller, F; Iannotti, GR; Korff, C; Michel, C; Pittau, F; Seeck, M; Vulliemoz, S; Wiest, R, 2016) |
| "Epilepsy is one of the major neurological disorders frequently associated with psychiatric disorders such as depression." | ( Goel, RK; Singh, T, 2016) |
| "Epilepsy is one of the most common symptoms in Tuberous Sclerosis Complex (TSC), appearing mainly in the first year of life and often resistant to therapy." | ( Estalella-Mendoza, A; Flores-González, JC; Hernández-González, A; Lechuga-Sancho, AM; Quintero-Otero, S; Rubio-Quiñones, F; Saldaña-Valderas, M, 2016) |
| "Epilepsy is a condition where patients have seizures due to abnormal nerve impulses in the brain." | ( Amalakanti, S; Athina, S; Bolla, HB; Daggumati, R; Devanaboina, AK; Gajula, RK; Lavu, H; Nagarjunakonda, S; Rajanala, L; Tata, RS; Uppala, V, 2017) |
| "Epilepsy is a debilitating seizure disorder that affects approximately 50 million people." | ( Jakobsen, S; Landau, AM; Lillethorup, TP; Nielsen, EH; Simonsen, M; Tasker, RA; Thomsen, MB; Wegener, G, 2016) |
| "Epilepsy is a disorder that affects 1-2% of the population and a significant percentage of these patients do not respond to anticonvulsant drugs available in the market suggesting the need to investigate new pharmacological treatments." | ( Coitinho, AS; Glassmann, D; Gomez, R; Marafon, P; Pereira, P; Vieira, V, 2016) |
| "Epilepsy is too complex to be considered as a disease; it is more of a syndrome, characterized by seizures, which can be caused by a diverse array of afflictions." | ( Akabani, G; Aramayo, R; Clanton, RM; Wu, G, 2017) |
| "Catamenial epilepsy is defined as an increase in the frequency of seizures during a particular phase of the menstrual cycle." | ( Khishfe, BF, 2017) |
| "Epilepsy is significantly more frequent in AD patients than in age-matched controls, even though the true extent of the phenomenon is not clear yet." | ( Bonuccelli, U; Giorgi, FS; Guida, M; Vergallo, A; Zaccara, G, 2017) |
| "Children with epilepsy are at an increased risk of injuries and hence need supervision." | ( Aneja, S; Jain, P; Sajjan, S; Seth, A; Sharma, S, 2016) |
| "Epilepsy is a common brain disorder characterized by the occurrence of recurring, unprovoked seizures." | ( Cai, M; Cai, S; Chen, L; Duan, S; Gu, H; Lin, R; Ling, C; Lu, J; Pan, X; Wang, Y; Zhu, H, 2017) |
| "Epilepsy is one of the most common neurological disorders, affecting about 2% of the population worldwide." | ( Arjunan, K; Eswaramoorthy, M; Jakki, SL; Nanjan, MJ; Senthil, V; Shanmuganathan, S; Yasam, VR, 2016) |
| "BACKGROUND Epilepsy is the most predominant neurological disorder characterized by recurrent seizures." | ( Hao, F; Jia, LH; Li, XW; Liu, XW; Zhang, YR, 2016) |
| "Epilepsy is a highly common chronic neurological disorder, manifested in many different types, affecting ~1% of the worldwide human population." | ( Bindila, L; Lerner, R; Loch, S; Lutz, B; Post, J, 2017) |
| "Epilepsy is a serious brain disorder with diverse seizure types and epileptic syndromes." | ( Chen, W; Gao, J; Li, XH; Li, YS; Lin, XY, 2016) |
| "Epilepsy is a complex, multifactorial disease characterized by spontaneous recurrent seizures and an increased incidence of comorbid conditions such as anxiety, depression, cognitive dysfunction, and sudden unexpected death." | ( Danbolt, NC; Dhaher, R; Eid, T; Gruenbaum, SE; Lee, TW; Zhou, Y, 2016) |
| "Epilepsy is thought to be associated with oxidative stress, glutamate excitotoxicity, and mitochondrial dysfunction." | ( Parvez, S; Raisuddin, S; Vishnoi, S, 2016) |
| "Epilepsy is one of the major neurological disorders frequently associated with psychiatric disorders such as depression." | ( Goel, RK; Kaur, T; Singh, T, 2017) |
| "Epilepsy is a significant disorder for which approximately one-third of patients do not respond to drug treatments." | ( Baines, RA; Giachello, CN; Lin, WH, 2017) |
| "A cure for epilepsy is currently not available, and seizure genesis, seizure recurrence, and resistance to antiseizure drugs remain serious clinical problems." | ( Bauer, B; Hartz, AM; Pekcec, A; Schlichtiger, J; Soldner, EL; Zhong, Y, 2017) |
| "Catamenial epilepsy is a common central nervous system disease in female, which is influenced by the 17-β-estradiol (estrogen) level during the menstrual cycle." | ( Huang, Y; Wang, G; Wang, X; Wang, Y; Zhang, Y, 2017) |
| "Hot water epilepsy is sensory epilepsy, wherein seizures are triggered by an unusual stimulus: contact with hot water." | ( Anand, A; Karan, KR; Satishchandra, P; Sinha, S, 2017) |
| "Thus, epilepsy is linked with a biomarker that might be related to accelerated brain aging and can be considered a neurobiological predisposition to later-life cognitive disorders." | ( Anttinen, A; Hermann, B; Joutsa, J; Karrasch, M; Rinne, JO; Shinnar, S; Sillanpää, M, 2017) |
| "Patients with epilepsy are frequently required to take antiepileptic drugs (AEDs) for a long period of time." | ( Chuang, MJ; Chuang, YC; Fu, TY; Lu, YT; Shih, FY; Tsai, MH; Tsai, WC, 2017) |
| "Epilepsy is the second most common disease of the brain." | ( Cho, KH; Chu, H; Chung, CK; Jeong, W, 2017) |
| "Epilepsy is a chronic neurological disorder, which is not only related to the imbalance between excitatory glutamic neurons and inhibitory GABAergic neurons, but also related to abnormal central cholinergic regulation." | ( Chen, Z; Wang, Y, 2017) |
| "Epilepsy is a common neurological disease characterized by abnormal temporary discharge of neurons in the central nervous system." | ( Chi, G; Huang, Z; Li, G; Li, X; Zhang, K, 2018) |
| "Epilepsy is one of the most common neurological disorders and the administration of antiepileptic drugs (AEDs) is the most common treatment." | ( Li, XM; Ma, XX; Ni, KM; Sun, P; Wei, X; Xu, M; Yang, CH; Yang, CR; Zhang, Y; Zhang, YJ, 2017) |
| "Epilepsy is a complicated neurological disorder that occurs worldwide and features several kinds of comorbidities in addition to recurrent seizures." | ( Guo, Y; Hu, Q; Kang, H; Lian, L; Liu, X; Xu, F; Zhang, N; Zhou, Q; Zhu, S, 2018) |
| "Epilepsy is complex neural disarray categorized by recurring seizures." | ( Cao, YL; Guo, XQ; Hao, F; Liu, XW; Wang, ML; Yan, ZR, 2017) |
| "Epilepsy is a chronic neurological condition, with over 30% of cases unresponsive to treatment." | ( Copmans, D; de Witte, PAM; Hunyadi, B; Siekierska, A; Sourbron, J, 2017) |
| "Epilepsy is a common neurological disease, manifested in unprovoked recurrent seizures." | ( Bekenstein, U; Berson, A; Friedman, A; Greenberg, DS; Hanin, G; Milikovsky, DZ; Mishra, N; Sheintuch, L; Soreq, H; Zelig, D, 2017) |
| "Epilepsy is fourth most common neurological disorders associated with depression and cognitive deficits." | ( Bagga, N; Gawande, DY; Goel, RK; Kaur, A; Kaur, N; Singh, T, 2017) |
| "Epilepsy is a common neurological condition with a worldwide prevalence of around 1%." | ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017) |
| "Epilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide." | ( Becker, HM; Deitmer, JW; Forero-Quintero, LS, 2017) |
| "Epilepsy is one of the most common neurologic disorders worldwide with no distinguishable cause in 60% of patients." | ( Asgari, T; Babaie, J; Choopani, S; Gharagozli, K; Golkar, M; Sayyah, M, 2017) |
| "Epilepsy is a highly prevalent neurological disorder." | ( Galván, EJ; Lara-Valderrábano, L; Rocha, L, 2017) |
| "Epilepsy is a spectrum of neurological disorders with many causal factors." | ( Chen, X; Durisic, N; Keramidas, A; Lynch, JW, 2017) |
| "Epilepsy is one of the most common neurological diseases in childhood and adolescence." | ( Hadzagic-Catibusic, F; Hasanbegovic, E; Melunovic, M; Uzicanin, S; Zubcevic, S, 2017) |
| "Epilepsy is prevalent and often medically intractable in Angelman syndrome (AS)." | ( Bey, AL; Cao, X; Chung, L; Jiang, YH; Kim, IH; Towers, AJ, 2018) |
| "Epilepsy is worldwide one of the most common neurologic diseases (prevalence 0." | ( Fauser, S; Tumani, H, 2017) |
| "Because epilepsy is associated with changes in functional brain connectivity, we studied the relationship between cortisol and changes in global and focal (node-centered) functional connectivity measures for individuals with stress-sensitive and non-stress-sensitive epilepsy." | ( Braun, KPJ; den Heijer, JM; Jansen, FE; Joels, M; Lorraine Hompe, E; Otte, WM; Sander, JW; van Campen, JS; van Diessen, E; Zijlmans, M, 2018) |
| "Epilepsy is one of the most prevalent neurological disorder affecting more than 50 million people worldwide." | ( Jamwal, S; Koshal, P; Kumar, P, 2018) |
| "Epilepsy is one in every of the foremost important chronic neurological disorders with high incidence worldwide." | ( Bari, SB; Cheke, RS; Firke, SD; Patil, RR, 2018) |
| "Epilepsy is a neurological disease that affects more than 70 million people worldwide and is characterized by the presence of spontaneous unprovoked recurrent seizures." | ( Copmans, D; De Borggraeve, W; de Witte, PAM; Dehaen, W; Exarchou, V; Foubert, K; Kim, Y; Ny, A; Orellana-Paucar, AM; Pieters, L; Siekierska, A; Steurs, G; Zhang, Y, 2018) |
| "Epilepsy is a common symptom in patients with glioblastoma (GB)." | ( Arrieta, O; Balaña, C; Bermúdez, S; Bernal, L; Cardona, AF; Carranza, H; Franco, S; Gil-Gil, M; Hakim, EJ; Hakim, F; Mayor, LC; Mejía, JA; Ortíz, C; Ortíz, LD; Otero, J; Rojas, L; Ruiz-Patiño, A; Useche, N; Vargas, C; Wills, B; Zatarain-Barrón, ZL, 2018) |
| "Epilepsy is a chronic brain disease affecting millions of individuals." | ( Chen, X; Dong, G; Liu, Y; Lu, R; Wang, L; Yun, W; Zhou, X, 2018) |
| "Epilepsy is among the most common neurological disorders." | ( Du, J; Han, Y; Jin, H; Li, Q; Niu, M; Qin, J; Zhang, J, 2018) |
| "Epilepsy is a common neurological condition with a worldwide prevalence of around 1%." | ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017) |
| "Epilepsy is one of the most common neurological diseases and it causes profound morbidity and mortality." | ( Chen, Q; Fazeli, W; Fricke, O; Kamsteeg, EJ; Li, X; Oundjian, NJ; Poschmann, S; Snoeijen-Schouwenaars, FM; Wang, QK; Willemsen, M, 2018) |
| "Epilepsy is a common disease of the central nervous system." | ( Lian, Y; Xie, N; Zhang, H; Zheng, Y, 2018) |
| "Chronic epilepsy is typified by spontaneous recurrent seizures, cognitive dysfunction, and depression, which are associated with persistent inflammation, significantly waned neurogenesis, and abnormal synaptic reorganization." | ( Castro, OW; Shetty, AK; Upadhya, D; Upadhya, R, 2018) |
| "Epilepsy is one of the common diseases seriously threatening life and health of human." | ( Deng, XQ; Song, MX, 2018) |
| "Epilepsy is a chronic and recurrent disease of the central nervous system, with a complex pathology." | ( Miao, W; Shi, Y; Teng, J; Zhang, L, 2018) |
| "Epilepsy is one of the most common neurological diseases, and current antiepileptic drugs fail to suppress seizure occurrence in around one third of epileptic patients." | ( Aguiar, GPS; Bertoncello, KT; Oliveira, JV; Siebel, AM, 2018) |
| "Epilepsy is a common pediatric neurological condition with frequent psychiatric comorbidities, including ADHD." | ( Choudhary, A; Gulati, S; Sagar, R; Sankhyan, N; Sripada, K, 2018) |
| "Purpose/Aim: Epilepsy is a complex, chronic neurological disorder characterized by increased and abnormal synchronization of neuronal electrical activity, which is manifested as seizures." | ( Saha, L; Singh, N; Vijayanti, S, 2018) |
| "The prevalence of epilepsy is estimated 5-10 per 1000 population and around 70% of patients with epilepsy can be sufficiently controlled by antiepileptic drugs (AEDs)." | ( Andres-Mach, M; Czuczwar, M; Czuczwar, SJ; Kruszyński, K; Łukawski, K; Łuszczki, JJ, 2018) |
| "Epilepsy is a serious neurological disease affecting about 1% of people worldwide (65 million)." | ( Kondrat-Wróbel, MW; Łuszczki, JJ, 2018) |
| "People with epilepsy are at increased risk of mortality, but, to date, the cause-specific risks of all unnatural causes have not been reported." | ( Ashcroft, DM; Carr, MJ; DelPozo-Banos, M; Gorton, HC; John, A; Webb, RT, 2018) |
| "The prevalence of epilepsy is increased in multiple sclerosis (MS), but information on AED treatment and seizure outcome is scarce." | ( Burman, J; Dagiasi, I; Kumlien, E; Vall, V; Zelano, J, 2018) |
| "Epilepsy is a common neurologic disorder requiring continued treatment during pregnancy." | ( Costa, R; Gama, H; Graça, J; Magalhães, LM; Moreira, J; Rocha, JF; Soares-da-Silva, P; Vieira, M, 2018) |
| "Individualised epilepsy care is the gold standard, not blanket bans on drug choice based on gender." | ( Lawthom, C, 2018) |
| "Epilepsy is a kind of disease with complicated pathogenesis." | ( Lu, D; Ouyang, P; Yang, S, 2018) |
| "Epilepsy is a common neurological disorder and is not well controlled by available antiepileptic drugs (AEDs)." | ( Dong, K; Gao, B; Huang, DK; Li, WZ; Wu, WN; Wu, Y; Yang, YJ; Yin, YY; Zhou, J, 2018) |
| "Epilepsy is one of the chronic and heterogeneous epidemic neurological disorders leading to substantial mortality." | ( Banik, S; Das, A; Hossain, MS; Hussain, ME; Islam, MS; Karmakar, P; Sarwar, MS, 2019) |
| "Epilepsy is one of the furthermost common neurodegenerative diseases affecting above 50 million individuals worldwide." | ( El-Azab, MF; Moustafa, YM; Tawfik, KM, 2018) |
| "Epilepsy is a kind of neurogenic diseases with high prevalence and characterized by seizure, brain paradoxical discharge and convulsion in spontaneous, transient, recurrent and uncontrolled manner." | ( Song, DQ; Tang, S; Zhang, JP; Zheng, YM, 2016) |
| "Epilepsy is a chronic neurological disorder which affects 65 million worldwide population and characterized by recurrent seizure in epileptic patients." | ( Kumari, S; Mishra, CB; Siraj, F; Tiwari, AK; Tiwari, M; Yadav, R, 2018) |
| "Epilepsy is associated with increased morbidity and mortality together and places a large financial burden on individuals and society." | ( Chen, Y; Fajol, A; Ren, B; Shi, S; Song, S, 2018) |
| "Epilepsy is a major public health issue in low- and middle-income countries, where the availability and accessibility of quality treatment remain important issues, the severity of which may be aggravated by poor quality antiepileptic drugs (AEDs)." | ( Auditeau, E; Ba, A; Dufat, H; Dugay, A; Jost, J; Jousse, C; Kariuki, SM; Leremboure, M; Mafilaza, Y; Newton, CR; Ngoungou, E; Nguyen, TL; Nguyen, TT; Preux, PM; Raharivelo, A; Ratsimbazafy, V; Sivadier, G; Traïkia, M, 2018) |
| "Epilepsy is a neurological disorder with a multitude of underlying causes, which may include infection with Onchocerca volvulus, the parasitic worm that causes human onchocerciasis." | ( Colebunders, R; Greter, H; Hendy, A; Kakorozya, A; Makunde, WH; Matuja, W; Mmbando, BP; Mnacho, M; Suykerbuyk, P, 2018) |
| "Epilepsy is a common neurological disease characterized by recurrent unpredictable seizures." | ( Kennedy, RT; Luna-Munguia, H; Stacey, WC; Zestos, AG, 2019) |
| "Epilepsy is one of the most common neurological disorders affecting millions of people." | ( Bu, G; Chen, Z; Li, Y; Pan, G; Xu, H; Zhang, Y; Zheng, H, 2018) |
| "Epilepsy is one of the most prevalent and drug-refractory neurological disorders." | ( Chen, G; Gao, X; He, M; Hu, Y; Li, Y; Ma, Y; Tian, X; Wang, Q; Wang, W; Wang, X; Xu, D; Yang, Q; Yang, Y; Zheng, F; Zhou, R, 2018) |
| "Epilepsy is a chronic medical disease and is associated with comorbid adverse somatic conditions due to epilepsy itself or its long-term treatment." | ( Hamed, SA; Oseilly, AM, 2018) |
| "Epilepsy is a chronic neurological disorder affecting an estimated 50 million people worldwide." | ( Chen, W; He, Q; Hu, Y; Jiang, L; Man, S; Wu, L, 2018) |
| "BACKGROUND Epilepsy is a complex neurologic disorder with abnormal electrical impulses in the brain." | ( Han, Z; Wang, H; Xia, J; Zhang, Q, 2018) |
| "Epilepsy is a neurological disease with high global prevalence." | ( Blanco, JR; Gómez-Eguílaz, M; Pérez-Martínez, L; Ramón-Trapero, JL, 2018) |
| "Epilepsy is a neurological disorder that significantly impacts the quality of life of affected persons." | ( Coppola, G; Greco, M; Iezzi, ML; Operto, F; Varriale, G; Verrotti, A, 2018) |
| "Epilepsy is a brain disorder characterized by a predisposition to suffer epileptic seizures." | ( González, MI; Lam, PM, 2019) |
| "Epilepsy is a progressive neurological disease characterized by recurrent seizures and behavioral comorbidities." | ( Barker-Haliski, M; Bazelot, M; Glyn, S; Jones, N; McNeish, AJ; Patra, PH; Sandhu, H; Whalley, BJ; White, HS; Williams, CM, 2019) |
| "Epilepsy is a common clinical syndrome characterized by sudden and recurrent attacks and temporary central nervous system dysfunction caused by excessive discharge of neurons in the brain." | ( Chen, C; Duan, J; Guo, J; Guo, S; Qian, D; Shang, E; Tang, Z; Yan, H; Zhao, M; Zhu, Y; Zhu, Z, 2019) |
| "In vivo models of epilepsy are available to explore such epileptogenic mechanisms, also assessing the efficacy of chemoprevention and therapy strategies at the pre-clinical level." | ( Albertini, MC; Ambrogini, P; Bartolini, D; Betti, M; Cuppini, R; Di Palma, M; Galli, F; Lattanzi, D; Marinelli, R; Minelli, A; Torquato, P, 2019) |
| "Epilepsy is a common life-threatening neurological disorder that is often drug-resistant and associated with cognitive impairment." | ( Chen, M; Jia, C; Jiao, H; Wei, L; Yang, H; Yin, W; Zhang, R, 2019) |
| "Epilepsy is a neurological disorder of the central nervous system characterized by hypersynchronized neuronal activity and has been associated with oxidative stress." | ( Díaz-Ruíz, A; Flores-Espinosa, P; Manjarrez, J; Méndez-Armenta, M; Nava-Ruíz, C; Ruíz-Díaz, A; Yescas-Gómez, P; Zaga-Clavellina, V, 2019) |
| "Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures." | ( Fei, Y; Han, Y; Ji, Z; Long, Y; Song, Z; Yang, H; Zheng, W; Zhuang, K, 2019) |
| "Epilepsy is the most prevalent neurological disorder in the pediatric age group with a prevalence of 3." | ( Agadi, JB; Nagabushana, D; S, PK, 2019) |
| "Epilepsy is one of the common neurological illnesses which affects millions of individuals globally." | ( Gebre, AK; Surur, A; Wondafrash, DZ; Yimer, EM, 2019) |
| "Epilepsy is a multi-etiological brain dysfunction syndrome." | ( Gao, L; Hou, S; Li, J; Liu, A; Liu, N; Ma, Z; Qiao, Z; Shen, H; Wang, F; Wei, L; Zhang, X, 2019) |
| "Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly used antiepileptic drugs." | ( Amagata, A; Ashley, EA; Bertini, E; Bruegger, JJ; Carrozzo, R; Chapman, KA; Dionisi-Vici, C; Enns, GM; Gahl, W; Hinman, A; Hoff, KG; Holst, CR; Johnson, SC; Kahn-Kirby, AH; Kim, V; Klein, MB; Kosaka, Y; Latham, JC; Maeder, CI; Malone, SA; Martinelli, D; Mei, JJ; Saneto, RP; Shrader, WD; Sideris, S; Trimmer, JK; Wang, L; Wheeler, MT; Wolfe, L, 2019) |
| "People with epilepsy are at increased risk for neuropsychological dysfunction due to multiple factors, of which the most amendable are antiseizure medications (ASMs)." | ( Boyd, A; Falco-Walter, J; Le, S; Loring, DW; Meador, KJ; Razavi, B; Seliger, J, 2019) |
| "Epilepsy is one of the most devastating neurological diseases and despite significant efforts there is no cure available." | ( Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lepsveridze, E; Lortkipanidze, T; Margvelani, G; Solomonia, R; Tsverava, L, 2019) |
| "Epilepsy is a chronic neurological disorder which affects not only the health of the affected child, but also has an economic, psychological and emotional impact on the family as a whole." | ( Kadwa, RA; Kaushik, JS; Mittal, R; Sahu, JK; Sharma, S, 2019) |
| "Epilepsy is accompanied by angiogenesis and blood-brain barrier (BBB) disruption." | ( Gao, X; Pan, X; Sun, H; Wang, Q; Yu, H; Yu, J; Zhang, M; Zhang, Y; Zhu, W, 2019) |
| "Epilepsy is a prevalent neurological disorder that was reported to affect about 56 million people in the world." | ( Guo, F; Li, X; Liu, N; Ma, L; Sun, T; Yu, J; Zhang, X; Zheng, P; Zhou, R, 2019) |
| "Epilepsy is a group of neurological disorders characterized by recurrent seizures that disturbs about 60 million people worldwide." | ( Bai, Y; Chen, X; He, X; Sun, Y; Wu, S; Xie, J; Zhang, Y; Zhao, Z; Zheng, X, 2019) |
| "Epilepsy is the most common brain disease in dogs." | ( Bathen-Nöthen, A; Berk, BA; Jokinen, TS; Knebel, A; Law, TH; Packer, RMA; Pelligand, L; Tipold, A; Volk, HA; Wessmann, A, 2019) |
| "Epilepsy is a group of neurological disorders which affects millions of people worldwide." | ( Kaszas, A; Malliaras, GG; Proctor, CM; Slezia, A; Williamson, A, 2019) |
| "The incidence of epilepsy is very high; hence, taking into consideration the factors associated with it during the implementation of a treatment strategy may reduce its overall load." | ( Dismand, H; Donald, A; Mendinatou, A; Thierry, A, 2019) |
| "Epilepsy is a chronic neurological disease characterized by an enduring propensity for generation of seizures." | ( Balosso, S; Ravizza, T; Vezzani, A, 2019) |
| "Epilepsy is characterized by spontaneous seizures." | ( An, D; Chen, L; Men, C; Qi, M; Wang, Z; Xu, W; Zhan, Y; Zhou, L, 2019) |
| "Epilepsy is a common worldwide neurological disorder." | ( Al-Hajje, A; Boumediene, F; Jost, J; Mroueh, L; Preux, PM; Ratsimbazafy, V; Salameh, P, 2019) |
| "Epilepsy is a common chronic disease of the central nervous system that can last for years or even decades, causing serious adverse effects on the body, mind, and psychology of patients." | ( Qian, S; Tu, W, 2019) |
| "Epilepsy is a neurological disorder characterized by an enduring predisposition to generate and aggravate epileptic seizures affecting around 1% of global population making it a serious health concern." | ( H S, N; K L, K; Paudel, YN, 2019) |
| "Epilepsy is a prominent neurological disorder that affects millions of people worldwide." | ( Furness, AM; Lunte, CE; Lunte, SM; Michealis, EK; Pal, R, 2019) |
| "Epilepsy is one of the most common chronic neurological conditions." | ( Bak, LK; Jensen, CD; Kjær, C; Krarup, S; Lindholm, SEH; Mertz, C; Pinborg, LH, 2020) |
| "Epilepsy is a common neurological condition, characterised by recurrent seizures." | ( Bresnahan, R; Marson, AG; Martin-McGill, KJ; Milburn-McNulty, P; Powell, G; Sills, GJ, 2019) |
| "Drug-resistant epilepsy is the main risk factor for future intellectual disability in patients with tuberous sclerosis complex." | ( Borkowska, J; Chmielewski, D; Domańska-Pakieła, D; Głowacka, J; Jozwiak, S; Kaczorowska-Frontczak, M; Kotulska, K; Sadowski, K; Sijko, K; Słowińska, M; Łojszczyk, B, 2019) |
| "Epilepsy is a chronic neurological disease." | ( Guo, C; Guo, K; Hu, Z; Li, J; Liu, R; Peng, J; Wu, S; Zhang, W, 2019) |
| "Epilepsy is one of the most widespread neurological diseases characterized by spontaneous recurrent seizures." | ( Bilanishvili, IG; Gamkrelidze, GN; Kandashvili, M; Kokaia, M; Lordkipanidze, T; Nanobashvili, ZI; Solomonia, RO, 2019) |
| "Epilepsy is a chronic and severe neurological disorder." | ( Gong, SJ; Huang, WL; Wu, ZS, 2019) |
| "Patients with epilepsy are often affected by not only seizures but also a variety of cognitive and psychiatric comorbidities that further impair their quality of life." | ( Takechi, K, 2019) |
| "Epilepsy is one of the most common neurological disorders worldwide, with an age-adjusted prevalence of 4 to 8 per 1000 population and an age-adjusted incidence of 44 per 100,000 person-years in developed countries." | ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2019) |
| "Epilepsy is a common neurological disorder." | ( Karyakin, VB; Malkin, SL; Postnikova, TY; Romanova, IV; Smolensky, IV; Zaitsev, AV; Zakharova, MV; Zavyalov, V; Zubareva, OE, 2019) |
| "CSNK2B-related epilepsy is relatively easy to be controlled." | ( Cai, S; Gao, K; Hu, W; Huang, S; Jiang, Y; Li, J; Liu, Y; Wang, J; Wang, Y; Wu, Y; Xie, H; Yan, H; Yang, Z; Yu, S; Zha, J, 2019) |
| "Epilepsy is a debilitating neurological illness that affects all aspect of an individual life." | ( Alese, OO; Mabandla, MV; Mkhize, NV; Rakgantsho, C; Zulu, S, 2020) |
| "Epilepsy is a highly prevalent disease characterized by recurrent, spontaneous seizures." | ( Buchanan, GF; Joyal, KG; Petrucci, AN; Purnell, BS, 2020) |
| "Epilepsy is a disease characterized by seizures which impair human life considerably." | ( Aygun, H; Sumbul, O, 2020) |
| "Epilepsy is a chronic disease characterized by recurrent unprovoked seizures." | ( Huntsman, RJ; Shackelford, AE; Tang-Wai, R, 2020) |
| "Epilepsy is characterized by oxidative stress in the brain." | ( Huang, W; Li, S; Li, Z; Liu, Z; Song, D, 2020) |
| "Epilepsy is a neurological disorder characterized by the presence of seizures and neuropsychiatric comorbidities." | ( da Silva-Júnior, RMP; Do Val-da Silva, RA; Garcia-Cairasco, N; Lazarini-Lopes, W; Leite, JP, 2020) |
| "Even though Epilepsy is a significant clinical issue in ATP1A3 patients, only a minority of publications provide any information about patients' anti-epileptic treatment." | ( Abicht, A; Biskup, S; Boonsimma, P; Borggraefe, I; Gasser, M; Ittiwut, C; Krenn, M; Kuersten, M; Milenkovic, I; Netbaramee, W; Roser, T; Shotelersuk, V; Srichomthomg, C; Suphapeetiporn, K; Tacke, M; von Stülpnagel, C; Wagner, M; Wechapinan, T; Zimprich, F, 2020) |
| "Epilepsy is a syndrome specified by frequent seizures and is one of the most prevalent neurological conditions, and that one-third of people of epilepsy are resistant to available drugs." | ( Ahmad, MA; Akbar, M; Pottoo, FH, 2020) |
| "Epilepsy is a widespread neurological disease characterized by abnormal neuronal activity resulting in recurrent seizures." | ( Dib, L; Fontana, A; Fritschy, JM; Gschwind, T; Lafourcade, C; Paterna, JC; Rambousek, L, 2020) |
| "Epilepsy is the most common chronic neurologic disorder which affects an estimated 10." | ( Ayalew, AF; Beyene, A; Birhan, T; Mulat, G; Simachew Kassa, A, 2020) |
| "Prevention of epilepsy is a great unmet need." | ( Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M, 2020) |
| "Epilepsy is a devastating neurological condition characterized by long-term tendency to generate unprovoked seizures, affecting around 1-2 % of the population worldwide." | ( Angelopoulou, E; Gnatkovsky, V; Othman, I; Paudel, YN; Piperi, C; Shaikh, MF, 2020) |
| "Epilepsy is a neurological disorder characterized by the occurrence of spontaneous and recurrent seizures." | ( Kumar, P; Kumar, V; Mishra, M; Prakash, C; Sharma, D, 2021) |
| "Patients with epilepsy are at increased risk for mental health and substance abuse disorders." | ( Bishu, KG; Fox, J; Lekoubou, A; Ovbiagele, B, 2020) |
| "Epilepsy is a common neurological disorder characterized by recurrent epileptic seizures." | ( Chen, F; Dong, X; Guo, C; Hou, S; Hu, Q; Jiao, Q; Li, Y; Liu, A; Liu, N; Shen, H; Wang, F; Wei, L; Wei, S; Wu, T; Yuan, S; Zhang, K; Zhang, X, 2020) |
| "Epilepsy is one of the most common neurological diseases." | ( Bakir, D; Cigdem, B; Dogan, HO; Ersan, S, 2020) |
| "Early-onset epilepsy is frequent and can be pharmacoresistant." | ( Billiemaz, K; Ceballos, I; Denommé-Pichon, AS; Héron, B; Imbard, A; Kuentz, P; Marie, S; Piraud, M; Ramond, F; Rio, M; Touraine, R; Vincent, MF, 2020) |
| "Epilepsy is often associated with emotional disturbances and the endocannabinoid (eCB) system tunes synaptic transmission in brain regions regulating emotional behavior." | ( Colangeli, R; Hill, MN; Morena, M; Pittman, QJ; Teskey, GC, 2020) |
| "Epilepsy is one of the most common neurological diseases." | ( Dong, J; Gan, G; Hu, S; Li, X; Yang, J; Yao, Y; Zhang, A; Zhang, C; Zhengxie, J; Zhu, X, 2020) |
| "The causes of epilepsy are diverse and not always known but one gene mutated in a small subpopulation of patients is phosphatase and tensin homolog (PTEN)." | ( Danzer, SC; Gross, C; MacLeod, MC; Tiwari, D; White, AR, 2020) |
| "Children with epilepsy are challenging for teleconsultation as direct information from the patient is missing, regarding seizures and adverse effects, especially behavioral and psychological side effects." | ( Dawman, L; Panda, P; Panda, PK; Sharawat, IK, 2020) |
| "Epilepsy is a pivotal neurological disorder characterized by the synchronous discharging of neurons to induce momentary brain dysfunction." | ( Cao, Q; Wang, H; Yang, F, 2021) |
| "Epilepsy is a neuropsychiatric disorder, which does not have any identifiable cause." | ( Gautam, M; Thapa, G, 2021) |
| "Epilepsy is very difficult to treat and often involves the combination of two or more AEDs." | ( Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H, 2020) |
| "Epilepsy is one of the most common diseases of the central nervous system." | ( Guo, C; Guo, K; Hu, Z; Li, J; Liu, R; Peng, J; Wu, S; Zhang, X, 2020) |
| "A major source of epilepsy is Neurocysticercosis (NCC), caused by Taenia solium infection." | ( Carabin, H; Drevets, DA; Evangeline, B; Hanas, JS; Hocker, JRS; Oommen, A; Prabhakaran, V; Rajshekhar, V, 2020) |
| "New mouse models of epilepsy are needed to better understand the complex genetic architecture of seizures and to identify therapeutics." | ( Bell, TA; Dalton, KA; Gu, B; Hock, P; Miller, DR; Pan, Y; Pardo-Manuel de Villena, F; Philpot, BD; Shaw, GD; Shorter, JR; Williams, LH, 2020) |
| "The onset of epilepsy is most prevalent between 1 and 3 years of age; however, approximately 25% of patients developed epilepsy before one year of age." | ( Samanta, D, 2021) |
| "Epilepsy is a common neurological disease and its most common type is temporal lobe epilepsy (TLE)." | ( He, H; Huang, Y; Lin, L; Pan, X; Wang, L; Wu, Y; Zhang, Y; Zhao, Y, 2021) |
| "The incidence of epilepsy is higher in AD patients with shared neuropathological hallmarks in both disease states, including the formation of neurofibrillary tangles." | ( Exley, C; Mold, MJ; Morris, B; O'Farrell, A, 2020) |
| "Epilepsy is one of the most common neurological complications in pregnancy; some women continue to use antiepileptic drugs (AEDs) to control seizures." | ( Furugen, A, 2020) |
| "Epilepsy is a syndrome involving chronic recurrent transient brain dysfunction." | ( Li, YZ; Sun, Z; Xu, HR; Zeng, CQ; Zhang, QG, 2020) |
| "Epilepsy is a chronic brain disease characterized by recurrent seizures." | ( Feixiang, S; Guo, M; Haiyan, G; Jiahang, S; Jie, L; Shengjie, S; Sihua, Q; Xiaoying, G; Yanmei, Z; Ying, C, 2020) |
| "Epilepsy is a common chronic neurological condition characterized by recurrent seizures." | ( Miyata-Nozaka, Y; Omar, H; Raymond, AA; Tan, HJ; Wong, SW; Zain, SM, 2021) |
| "Epilepsy is a chronic neurological disease characterized by recurrent epileptic seizures." | ( Biembengute, MEF; Boleti, APA; Cardoso, PHO; de Moraes, LFRN; E Silva, PS; Frihling, BEF; Koolen, HHF; Migliolo, L; Rodrigues, TAA, 2022) |
| "Epilepsy is a chronic disease, while epileptogenesis is a latent period where brain will be transformed into an epileptic one." | ( Chen, L; Gong, M; Kinoshita, M; Lai, W; Li, W; Peng, A; Qiu, X; Yang, L; Zhang, L; Zheng, W, 2020) |
| "Epilepsy is characterized by a progressive predisposition to suffer seizures due to neuronal hyperexcitability, and one of its most common co-morbidities is cognitive decline." | ( Bonansco, C; Fuenzalida, M; Guiffa, F; Martorell, A; Wellmann, M, 2020) |
| "Epilepsy is a chronic nervous system disease." | ( Chen, Q; Chen, Y; Feng, Z; Huang, H; Peng, Y; Wang, J; Xu, Z; Zeng, J; Zhang, H; Zhang, J; Zhou, X, 2020) |
| "Epilepsy is a chronic brain disease affecting millions of people worldwide." | ( Mosaferi, B; Najdi, N; Salari, AA; Zeraati, M, 2021) |
| "Epilepsy is one of the most common neurological disorders that severely affect the life quality of many people worldwide." | ( Ergul, M; Gumus, E; Ozdemir, E; Taskıran, AS, 2020) |
| "Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent seizurescaused by abnormal neuronal activity in the brain." | ( Akyuz, E; Angelopoulou, E; Eroglu, E; Kullu, I; Paudel, YN; Polat, AK, 2021) |
| "Drug-resistant epilepsy is a problem worldwide." | ( Kong, FC; Lang, LQ; Ma, CL; Zhong, MK, 2021) |
| "Epilepsy is one of the most common neurological disorders, affecting approximately 50 million people worldwide." | ( Beydoun, A; DuPont, S; Lagae, L; Matta, M; Nagire, V; Zhou, D, 2020) |
| "Epilepsy is a devastating neurological disorder characterized by the repeated occurrence of epileptic seizures." | ( Akyuz, E; Angelopoulou, E; Dundar, HE; Paudel, YN; Polat, AK, 2021) |
| "Epilepsy is a chronic neurodegenerative disease that has seriously threatened human health." | ( Cheng, Z; Luo, X; Wang, R; Yu, F, 2021) |
| "Epilepsy is a neurological condition characterized by synchronous neuronal oscillations (seizures) in the electroencephalogram." | ( Crunelli, V; Deidda, G; Di Giovanni, G, 2021) |
| "Epilepsy is accompanied by abnormal neurotransmission, and microRNAs, as versatile players in the modulation of gene expression, are important in epilepsy pathology." | ( Li, Y; Wang, P; Wang, Z; Yang, A; Zhang, Q; Zhang, Y, 2021) |
| "Epilepsy is a frequent chronic disorder of the brain characterized by intermittent epileptic seizures caused by hypersynchronous discharge of neurons in the brain." | ( Ghafouri-Fard, S; Hashemi, M; Hussen, BM; Omrani, MA; Rafigh, M; Sayad, A; Taheri, M, 2021) |
| "Epilepsy is the disease associated with seizures and convulsions." | ( Anwar, F; Arshad, S; Khan, MM; Najm, S; Naureen, H; Rehman, S; Sultana, K, 2020) |
| "Epilepsy is a chronic neurobehavioral disorder whereby an imbalance between neurochemical excitation and inhibition at the synaptic level provokes seizures." | ( Flores-Soto, M; González-Burgos, I; Martín-Amaya-Barajas, FL; Orozco-Suárez, S; Romero-Guerrero, C; Tejeda-Martínez, A; Vázquez-Hernández, N, 2021) |
| "In Morocco, epilepsy is one of the major neurological health conditions, with an estimated prevalence of 1." | ( Cherkaoui Rhazouani, O; Khramaz, M; Kissani, N; Mebrouk, Y; Meryem, C; Ouazzani, R; Souirti, Z, 2021) |
| "Epilepsy is a neurological disease with significant effects in children." | ( Han, J; Li, Y; Wang, Y; Yang, Y, 2021) |
| "Epilepsy is common in patients with brain tumors and frequently presents as the first clinical manifestation of an underlying tumor." | ( Heugenhauser, J; Iglseder, S; Kerschbaumer, J; Muigg, A; Nowosielski, M; Stockhammer, G; Unterberger, I, 2021) |
| "Temporal lobe epilepsy is considered to be one of the most common and severe forms of focal epilepsies." | ( Schwarzer, C; Zangrandi, L, 2022) |
| "Epilepsy is one of the most common brain disorders, affecting more than 50 million people worldwide." | ( Bicker, J; Carona, A; Falcão, A; Fonseca, C; Fortuna, A; Silva, R, 2021) |
| "Epilepsy is the tendency to have unprovoked seizures." | ( Milligan, TA, 2021) |
| "Epilepsy is characterized by recurrent seizures due to abnormal hyperexcitation of neurons." | ( Kim, HY; Kim, JI; Suh, PG, 2021) |
| "Epilepsy is a result of unprovoked, uncontrollable, and repetitive outburst of abnormal and excessive electrical discharges, known as seizures, in the neurons." | ( Akyuz, E; Arulsamy, A; Kullu, I; Shaikh, MF, 2021) |
| "Epilepsy is the third most frequent neurological disorder in aged patients after stroke and dementia." | ( Rohracher, A; Trinka, E, 2021) |
| "Epilepsy is one of the most common neurological disorders, with individuals having an increased susceptibility of seizures in the first few years of life, making children at risk of developing a multitude of cognitive and behavioral comorbidities throughout development." | ( Binder, MS; Condon, SM; Darner, AM; Faust, AM; Hodges, SL; Kwok, EM; Lugo, JN; Nolan, SO; Quintero, SI; Senger, SS; Womble, PD, 2021) |
| "Epilepsy is a common chronic neurological disease caused by the over-synchronization of neurons leading to brain dysfunction." | ( Guo, Q; Hu, QP; Hu, RR; Huang, XY; Shi, HY; Zheng, YY, 2021) |
| "Epilepsy is a neurological disorder mainly characterised by recurrent seizures that affect the entire population diagnosed with the condition." | ( Farrelly, AM; Grintzalis, K; Vlachou, S, 2021) |
| "Epilepsy is a common neurological disease that affects more than 50 million people worldwide." | ( Liang, J; Wang, G; Wang, J; Wu, X; Xiao, J; Xin, C, 2021) |
| "Epilepsy is a common neurological disease that cannot be well controlled by existing antiepileptic drugs." | ( Cao, J; Li, X; Yang, J; Yu, L; Yu, W, 2021) |
| "Epilepsy is one of the most common and disabling chronic neurological disorders." | ( Klein, P; Löscher, W, 2021) |
| "Epilepsy is one of the most frequent neurological disorders characterized by an enduring predisposition to generate epileptic seizures." | ( Al-Rafiah, AR; Mehdar, KM, 2021) |
| "Epilepsy is a chronic encephalopathy and one of the most common neurological disorders." | ( Chen, D; Gan, CL; Hu, L; Lan, G; Lee, TH; Liu, H; Mei, Y; Shui, X; Wang, L; Xia, Y; Zhang, T; Zou, Y, 2021) |
| "Epilepsy is a chronic neurological disorder, characterized by the predisposition of unprovoked seizures affecting the neurobiological, psychological, cognitive, economic, and social wellbeing of the patient." | ( Akhtar, MJ; Khan, SA; Naim, MJ; Pal, R; Paul, J; Singh, K, 2022) |
| "Disclosure of epilepsy is a relevant but under-researched topic in epilepsy research." | ( Desai, N; Lachake, AV; Udani, V, 2021) |
| "Epilepsy is a chronic disease of the brain that affects approximately 50 million people globally, with over 80 % of them living in low- and middle-income countries (LMICs)." | ( Boumédiène, F; Bruand, PE; Mioramalala, SA; Preux, PM; Rafanomezantsoa, RM; Raharinivo, MM; Raharivelo, A; Ratsimbasoa, A; Vincent, C, 2021) |
| "Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks." | ( Al Kury, LT; Alattar, A; Alshaman, R; Alvi, AM; Feng, J; Khan, AU; Li, S; Muhammad, AJ; Shah, FA; Ullah, I, 2021) |
| "Childhood epilepsy is one of the most common neurological problems." | ( Athey, T; Bahl, S; Cordeiro, D; Mercimek-Andrews, S; Silver, G; Thakral, A, 2021) |
| "Epilepsy is the most common neurological disorder, affecting nearly 50 million people worldwide." | ( Al-Harrasi, A; Behl, T; Bhatia, S; Bungau, S; Kale, MB; Najda, A; Nurzyńska-Wierdak, R; Sehgal, A; Singh, S; Umare, MD; Upaganlawar, AB; Wankhede, NL, 2021) |
| "Epilepsy is a common neurological condition characterised by recurrent seizures." | ( Marson, AG; Milburn-McNulty, P; Panebianco, M, 2021) |
| "Epilepsy is a complex neurological syndrome characterized by seizures resulting from neuronal hyperexcitability and sudden and synchronized bursts of electrical discharges." | ( Dos Santos, WF; Fontana, ACK; Green, JL, 2021) |
| "Epilepsy is a common neurological disorder characterized by repeated and spontaneous epileptic seizures and is not well controlled by current medication." | ( Chen, Z; Wang, Y; Yang, L, 2022) |
| "Epilepsy is highly prevalent in patients with tuberous sclerosis complex (TSC)." | ( Curatolo, P; de Vries, PJ; Dlugos, DJ; Franz, DN; French, JA; Herbst, F; Ikeda, H; Lawson, JA; Nabbout, R; Pelov, D; Peyrard, S; Polster, T; Yapici, Z, 2021) |
| "Epilepsy is one of common neurological disorders, greatly distresses the well-being of the sufferers." | ( Gao, D; Jin, M; Li, N; Liu, K; Mou, L; Ren, Q; Sik, A; Zhang, M; Zhang, S, 2021) |
| "Epilepsy is a devastating neurological disorder characterized by recurrent seizures attributed to the disruption of the dynamic excitatory and inhibitory balance in the brain." | ( Akyuz, E; Angelopoulou, E; Koklu, B; Paudel, YN; Uner, A, 2022) |
| "Epilepsy is a common chronic neurological disease." | ( Chen, FF; Chen, YS; Feng, W; Hu, QP; Huang, XY; Peng, F; Yan, HX; Zhang, X; Zhou, YY, 2021) |
| "Epilepsy is one of the most common encountered neurological disorders." | ( Liu, D; Wang, Y, 2022) |
| "Epilepsy is one of the most common chronic neurological diseases." | ( Guo, C; Guo, K; Hu, Z; Li, J; Peng, J; Wu, S; Zhang, X; Zhang, Z, 2022) |
| "Epilepsy is a common chronic neurological disorder worldwide, but its entire pathology remains unknown." | ( Cheng, Y; Guo, W; Jia, Z; Li, G; Lu, Y; Pei, L; Yang, X; Zhang, S, 2022) |
| "Epilepsy is one of the most prevalent neurological conditions and carbamazepine is a commonly used anti-seizure drug (ASD), especially in developing nations." | ( Aghoram, R; Balachandran, M; Indira Priya, D; Jain, S; Meher, R; Nair, PP; Nandwani, S; Sreekumaran Nair, N; Wadwekar, V; Wagh, S, 2021) |
| "Epilepsy is the most common childhood neurological disorder in Nigeria." | ( Aronu, AE; Bisi-Onyemaechi, AI; Chikani, UN; Ojinnaka, NC; Uwaezuoke, NA, 2021) |
| "Epilepsy is a common neurological disorder characterized by abnormal and recurrent neuronal discharges that result in epileptic seizures." | ( Hernandez, L; Luna, R; Rosiles, A; Rubio, C; Taddei, E, 2022) |
| "Epilepsy is the most common chronic neurologic disorder characterized by the recurrence of unprovoked seizures." | ( Karthick, PA; Mathew, J; Ramakrishnan Manuskandan, S; Sivakumaran, N, 2021) |
| "Epilepsy is a disease that affects millions of people around the globe and has a multifactorial cause." | ( de Oliveira, MCVA; Duarte, FS; Pereira, MC; Pitta, IR; Pitta, MGR; Silva, AA; Viana, DCF, 2022) |
| "Epilepsy is one of the most common neurological disorders, whose development is typically detected via early seizures." | ( Duncan, D; Garner, R; Lai, M; Yıldız, İ, 2022) |
| "Epilepsy is a chronic neurological disorder that is treated with multiple medications that can have significant side effects." | ( Acikgoz, M; Aciman Demirel, E; Atasoy, HT; Celebi, U; Comert, E; Piri Cinar, B, 2022) |
| "Epilepsy is a chronic neurological disease that affects more than 50 million people worldwide." | ( Ateş, B; Çolakoğlu, N; Parlakpınar, H; Vardı, N; Yıldız, A, 2022) |
| "Epilepsy is a long-term recurrent chronic brain disease that can cause significant emotional burden to the patient and their family, as well as huge economic costs to society." | ( He, J; Wu, X; Zhou, D, 2022) |
| "Epilepsy is a severe neurological disease characterized by spontaneous recurrent seizures (SRS)." | ( Burjanadze, M; Dashniani, M; Gamkrelidze, G; Kandashvili, M; Kokaia, M; Lagani, V; Lepsveridze, E; Lordkipanidze, T; Solomonia, R; Tsverava, L, 2022) |
| "Epilepsy is one of the most common neurological disorders worldwide, with an age-adjusted prevalence of 4 to 8 per 1000 population and an age-adjusted incidence of 44 per 100,000 person-years in developed countries." | ( Bragazzi, NL; Brigo, F; Igwe, SC; Lattanzi, S, 2022) |
| "Epilepsy is one of the most common serious brain disorders, affecting about 1% of the population all over the world." | ( Abd El-Gawad, HS; Abd Elkader, HAE; Alhasani, RH; El-Sayed, SA; Essawy, AE; Tousson, E, 2022) |
| "Since autism and epilepsy are common neurodevelopmental disorders with high coincidence, we tested whether early-life chronic subconvulsive activity compared to convulsive activity alters handling, spatial memory, lateralization, coping strategy and the seizure threshold in a sex-dependent manner." | ( Friedman, LK; Kahen, BA; Velíšek, L; Velíšková, J, 2022) |
| "Epilepsy is an abnormal brain state that may be induced by synchronous neuronal activation and also abnormalities in energy metabolism or the oxygen supply vascular system." | ( Gao, DS; Hu, JM; Xi, W; Yin, L; Zhong, C, 2022) |
| "Epilepsy is one of the most common neurologic unit diseases that have different prevalence in different parts of the world." | ( Avan, R; Ershadi, F; Mousavi Mirzaei, SM; Roshanravan, B; Sahebnasagh, A; Tabrizi, N, 2022) |
| "Epilepsy is a neurological disease that pathologically affects brain functions." | ( Acar, S; Akbas, F; Gorucu Yilmaz, Ş; Meral, I; Okur, SK; Pala Acikgoz, N; Pala, M; Taslidere, E, 2022) |
| "Epilepsy is one of the most common neurological disorders, and it places a significant economic strain on the healthcare system around the world." | ( Abdallah, AAM; Ahmed, AE; Alotaibi, G; Bakri, AH; Halim, PR; Hassan, MH; Rashwan, NI, 2023) |
| "Epilepsy is a common neurological condition with a worldwide prevalence of around 1%." | ( Cividini, S; Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C, 2022) |
| "Epilepsy is a relatively complicated neurological disorder that results in seizures." | ( Aggarwal, NB; Akhter, J; Arora, I; Asad, M; Hoda, U; Rastogi, S; Samim, M; Siddiqui, MA, 2022) |
| "Epilepsy is a common neurological disorder affecting more than 70 million people worldwide." | ( Gao, Y; Jiang, X; Liang, X; Liu, W; Lu, H; Wang, N; Xing, B; Xu, X; Zhao, Q; Zhou, L, 2023) |
| "Epilepsy is a chronic neurological disorder that is characterized by episodes of seizure." | ( Guan, S; Liu, J; Qian, F; Wang, Y; Wu, H; Yang, J, 2022) |
| "Epilepsy is a common neurological condition induced by losing equilibrium of different pathway as well as neurotransmitters that affects over 50 million people globally." | ( Manavi, MA, 2022) |
| "Epilepsy is one of the most common neurological disorders affecting most social, economic and biological aspects of human life." | ( Abdelbasset, WK; Huldani, H; Jalil, AT; Jasim, SA; Margiana, R; Mohammad, HJ; Ridha, HS; Rudiansyah, M; Yasin, G, 2022) |
| "Epilepsy is increasing, being more common in older adults, with more than 20% of late-onset cases with unknown aetiology (LOEU)." | ( Aluisantonio, L; Chiaravalloti, A; Di Santo, S; Fernandes, M; Franchini, F; Izzi, F; Liguori, C; Manfredi, N; Mercuri, NB; Placidi, F; Schillaci, O, 2022) |
| "Epilepsy is a neurological disease that requires long-term antiepileptic drugs (AEDs)." | ( Abd El Hady, NMS; Abdallah, HM; Abdelmageed, SM; Aboelghar, HM; Garib, MI; Mahmoud, AA, 2022) |
| "Epilepsy is characterised by abnormal neuronal discharges, including aberrant expression of extracellular matrix (ECM) components and synaptic plasticity stabilisation." | ( Chen, L; Huang, H; Huang, Q; Niu, J; Ren, J; Su, X; Sun, T; Wan, D; Wang, P; Yang, L; Zhang, C, 2022) |
| "The challenges in epilepsy care in resource-limited regions were highlighted 10 years ago, and still remain an ongoing issue." | ( Fong, SL; Hung, SK; Khoo, CS; Lim, KS; Looi, I; Suppiah, PD; Tan, HJ; Tee, SK, 2022) |
| "Epilepsy is characterized by the occurrence of seizures, and the high prevalence of epilepsy-associated comorbidities affects the quality of patients' life." | ( Bertoncello, KT; Bonan, CD; Zanandrea, R, 2022) |
| "Epilepsy is a common neurological disorder which affects 50 million people worldwide." | ( Aguiar, GPS; Lima-Rezende, CA; Müller, LG; Oliveira, JV; Pedroso, J; Piato, A; Schneider, SE; Siebel, AM, 2022) |
| "Insular epilepsy is a great mimicker and can be mistaken for seizures originating from other areas of the brain or as nonepileptic spells." | ( Dieppa, M; Li, D; Perven, G; Podkorytova, I, 2022) |
| "Epilepsy is a neurological disease characterized by abnormal or synchronous brain activity causing seizures, which may produce convulsions, minor physical signs, or a combination of symptoms." | ( Belperio, G; Corso, C; Duarte, CB; Mele, M, 2022) |
| "Epilepsy is often considered to be a progressive neurological disease, and the nature of this progression remains unclear." | ( Cheng, P; Jia, P; Liao, S; Meng, K; Xiao, C; Xu, R; Zhao, X; Zheng, X, 2022) |
| "Epilepsy is characterized by seizures of diverse types that affect about 1-2% of the population worldwide." | ( Jiang, J; Li, W; Yu, Y, 2022) |
| "Epilepsy is a paroxysmal brain disorder that results from an imbalance between neuronal excitation and inhibition." | ( Deng, YC; Feng, Y; Gan, YJ; Li, GY; Liu, C; Qiao, XZ; Wei, ZH; Zhang, CC, 2022) |
| "Epilepsy is a chronic neurological disease with recurrent seizures." | ( Vasileva, Z, 2021) |
| "Epilepsy is a devastating brain disorder for which effective treatments are very limited." | ( Castillo, PE; Frechou, MA; Gonçalves, JT; Nasrallah, K; Persaud, S; Yoon, YJ, 2022) |
| "The prevalence of epilepsy is slightly higher in women than in men and sensitivity to seizure stimuli differs between sexes." | ( Cepeda, MS; Kern, DM; Novak, G; Teneralli, RE, 2022) |
| "PCDH19-related epilepsy is a rare X-linked type of epilepsy caused by genomic variants of the Protocadherin 19 (PCDH19) gene." | ( Dell'Isola, GB; Di Cara, G; Fattorusso, A; Imperatore, V; Mencaroni, E; Prontera, P; Striano, P; Tascini, G; Verrotti, A, 2022) |
| "Epilepsy is a chronic neurological disorder affecting 70 million people globally." | ( Banday, N; Batiha, GE; Bhat, MM; Mir, PA; Mir, RH; Mohi-Ud-Din, R; Pottoo, FH; Sawhney, G; Shah, AJ, 2022) |
| "Epilepsy is the second most prevalent neurodegenerative disease in the world." | ( López-López, F; Moreno, W; Rodríguez-Quintero, P; Rojas-Hernández, D; Rubio, C; Rubio-Osornio, M, 2022) |
| "People with epilepsy are at a higher risk of developing vascular disease." | ( Chen, Z; Kwan, P; Nicolo, JP; Nightscales, R; O'Brien, TJ, 2022) |
| "Epilepsy is one of the most common neurological disorders worldwide." | ( Amos, A; Escheu, G; Harrison, W; Hauke, P; Kaducu, J; Keller, L; Matuja, W; Ngowi, BJ; Ovuga, E; Pfausler, B; Richter, V; Schmidt, V; Schmutzhard, E; Stelzle, D; Welte, TM; Winkler, AS, 2022) |
| "Epilepsy is common in sub-Saharan Africa, often caused by neurocysticercosis or ischaemic strokes." | ( Amos, A; Escheu, G; Harrison, W; Hauke, P; Kaducu, J; Keller, L; Matuja, W; Ngowi, BJ; Ovuga, E; Pfausler, B; Richter, V; Schmidt, V; Schmutzhard, E; Stelzle, D; Welte, TM; Winkler, AS, 2022) |
| "Epilepsy is a widespread and mainly severe neurological condition portrayed by recurring spontaneous seizures caused by the brain's abnormal electrical activity." | ( Erbas, O; Erdogan, MA; Kirazlar, M, 2022) |
| "Epilepsy is a prevalent and frequently devastating neurological disorder defined by recurring spontaneous seizures caused by aberrant electrical activity in the brain." | ( Erbas, O; Erdogan, A; Erdogan, MA, 2023) |
| "Temporal lobe epilepsy is the most drug-resistant type with the highest incidence among the other focal epilepsies." | ( Behzadi, G; Davoudi, S; Hosseinmardi, N; Janahmadi, M; Khatibi, VA; Mirnajafi-Zadeh, J; Mohammadi, M; Nazari, M; Rahdar, M; Raoufy, MR; Rezaei, M, 2023) |
| "Epilepsy is one of the most common neurological disorders in childhood." | ( Bentley, R; Hu, G; Jiang, X; Lowe, S; Mei, H; Sun, C; Wu, Y; Xie, R; Zhao, W, 2022) |
| "Epilepsy is a neurological disorder caused by abnormally elevated neuronal firing and excitability." | ( Guo, Y; Hao, L; Jing, W; Peng, X; Wang, X; Yang, M; Yang, Y; Zhang, H, 2022) |
| "Epilepsy is a chronic neurological disorder and there is increasing evidence about the role of inflammation in epileptogenesis." | ( Barbosa, BB; Coitinho, AS; de Lima Rosa, G; Domingues, AM; Guzzo, EFM; Nunes, SEB; Padilha, RB; Siqueira, IR, 2022) |
| "Epilepsy is a common neurological condition, affecting over 70 million individuals worldwide." | ( Elkommos, S; Mula, M, 2022) |
| "Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications." | ( Alvestad, S; Bjørk, MH; Christensen, J; Dreier, JW; Gilhus, NE; Gissler, M; Igland, J; Leinonen, MK; Sun, Y; Tomson, T; Vegrim, HM; Zoega, H, 2022) |
| "Epilepsy is a neurological disease affected by an imbalance of inhibitory and excitatory signaling in the brain." | ( de Moura, JP; Dos Santos, AMF; Lopes, SM; Monteiro, AFM; Rodrigues, TCML; Scotti, L; Scotti, MT, 2023) |
| "Children with epilepsy are at increased risk of vitamin D deficiency." | ( Likasitthananon, N; Nabangchang, C; Numbenjapon, N; Phatarakijnirund, V; Suwanpakdee, P; Vichutavate, S, 2022) |
| "Epilepsy is a nervous system disease, and seizures are closely related to oxidative stress." | ( Ge, K; Jin, M; Liu, D; Liu, H; Ma, M; Wang, S; Yang, Y; Yin, C; Zhang, C; Zhang, J; Zhang, Y, 2022) |
| "Epilepsy is a common neurological disorder characterized by recurrent unprovoked seizures." | ( Appendino, JP; Au, PYB; Chahine, M; Ebdalla, A; Plumereau, Q; Poulin, H; Scantlebury, MH, 2022) |
| "Epilepsy is one of the most common brain disorder and, despite the possible use of several therapeutic options, many patients continue to have seizures for their entire lifespan and they need new therapeutic approaches." | ( Calvani, M; Giovannini, MG; Lana, D; Landucci, E; Magni, G; Mazzantini, C; Pellegrini-Giampietro, DE, 2022) |
| "Epilepsy is a neurological brain disease, and its recurrent seizures are related to the reductive substance-powered antioxidant defense system (ADS)." | ( Li, J; Qing, Z; Song, L; Wang, Q; Yang, R; Yang, S; Zhang, XB; Zhou, Y, 2022) |
| "Epilepsy is one of the most common and disabling chronic neurological diseases affecting people of all ages." | ( Engel, T; Wong, ZW, 2023) |
| "Epilepsy is one of the most common and refractory neurological disorders globally." | ( Liu, Y; Meng, J; Tao, X; Wang, F; Wang, W; Wang, Z; Xue, T; Yan, Z, 2023) |
| "Epilepsy is a brain disorder characterized by recurrent epileptic seizures and neurobiological, physiological, mood, and cognitive consequences." | ( Atanasova, M; Georgieva, K; Ioanidu, L; Nenchovska, Z; Shishmanova-Doseva, M; Tchekalarova, J; Uzunova, Y, 2022) |
| "Epilepsy is the results from the imbalance between inhibition and excitation in neural circuits, which is mainly treated by some chemical drugs with side effects." | ( Cao, C; Ji, Y; Lan, W; Li, G; Liu, X; Tao, J; Wang, C; Xue, H; Yao, Y; Zhang, S, 2022) |
| "Epilepsy is a chronic disease that affects a wide range of people." | ( Li, M; Li, S; Wang, S; Wu, J; Zhao, W, 2023) |
| "Epilepsy is a chronic disease that affects a wide range of people." | ( Li, M; Li, S; Wang, S; Wu, J; Zhao, W, 2023) |
| "Epilepsy is a chronic disease that affects a wide range of people." | ( Li, M; Li, S; Wang, S; Wu, J; Zhao, W, 2023) |
| "Epilepsy is one of the most common chronic diseases in children, and cannot be controlled with conventional antiepileptic drugs in 30% of cases." | ( Blažeković, I; Kolić, I; Prpić, I; Radić Nišević, J, 2021) |
| "Epilepsy is one of the most common chronic diseases in children, and cannot be controlled with conventional antiepileptic drugs in 30% of cases." | ( Blažeković, I; Kolić, I; Prpić, I; Radić Nišević, J, 2021) |
| "Epilepsy is one of the most common chronic diseases in children, and cannot be controlled with conventional antiepileptic drugs in 30% of cases." | ( Blažeković, I; Kolić, I; Prpić, I; Radić Nišević, J, 2021) |
| "Epilepsy is a neurological condition that causes unprovoked, recurrent seizures." | ( Jiang, S; Jin, WN; Li, Y; Shi, FD; Shi, K; Zhang, Z, 2023) |
| "Epilepsy is a neurological condition that causes unprovoked, recurrent seizures." | ( Jiang, S; Jin, WN; Li, Y; Shi, FD; Shi, K; Zhang, Z, 2023) |
| "Epilepsy is a disease which affects between 1 and 2% of the population, and a large proportion of these people do not react to currently available anticonvulsant medications, indicating the need for further research into novel pharmacological therapies." | ( Erbas, O; Erdogan, A; Erdogan, MA; Gurgul, S, 2023) |
| "Epilepsy is a disease which affects between 1 and 2% of the population, and a large proportion of these people do not react to currently available anticonvulsant medications, indicating the need for further research into novel pharmacological therapies." | ( Erbas, O; Erdogan, A; Erdogan, MA; Gurgul, S, 2023) |
| "Nocturnal epilepsy is a neurological disease that has a significant effect on sleep." | ( Ayala-Guerrero, F; Castro-Domínguez, D; Gutiérrez-Chávez, CA; Mateos-Salgado, EL; Mexicano-Medina, G, 2023) |
| "Nocturnal epilepsy is a neurological disease that has a significant effect on sleep." | ( Ayala-Guerrero, F; Castro-Domínguez, D; Gutiérrez-Chávez, CA; Mateos-Salgado, EL; Mexicano-Medina, G, 2023) |
| "Epilepsy is a group of chronic neurological disorders characterized by recurrent and abrupt seizures." | ( Chen, H; Ji, T; Jiang, Y; Liu, X; Wang, W; Yu, G; Zhan, X; Zhou, XH, 2022) |
| "Epilepsy is a common neurological disorder and glutamate excitotoxicity plays a key role in epileptic pathogenesis." | ( Mai, D; Qu, Q; Qu, S; Ren, S; Wang, J; Zhang, W; Zhang, Y, 2022) |
| "Epilepsy is a chronic neurological disorder that presents as recurrent, unprovoked seizures." | ( Chou, IC; Wang, HS; Yang, MT, 2023) |
| "Epilepsy is a common neurological disorder associated with alterations of excitation-inhibition balance within brain neuronal networks." | ( Bryson, A; Petrou, S; Reid, C, 2023) |
| "Epilepsy is characterized by the manifestation of spontaneous and recurrent seizures." | ( Bertoncello, KT; Bonan, CD, 2023) |
| "Epilepsy is one of the most common neurological disorders in the world." | ( Bonaccorso, A; Di Martino, P; Gigliobianco, MR; Lombardo, R; Mancuso, A; Musumeci, T; Pellitteri, R, 2023) |
| "Epilepsy is a common and severe neurological disorder in which impaired glucose metabolism leads to changes in neuronal excitability that slow or promote the development of epilepsy." | ( Chen, Y; Gu, H; Shan, Y; Sun, Y; Wang, Y, 2023) |
| "Epilepsy is a chronic neurological disorder characterized by recurrent unprovoked seizures." | ( Darwish, HA; Seleem, MM; Shaheen, AA; Zayed, AA, 2023) |
| "Epilepsy is a common, chronic neurological disorder characterized by recurrent spontaneous seizures." | ( Ai, M; Chen, H; Chen, L; Liu, Y; Mei, R; Pang, R; Xia, D; Zhang, L; Zhong, L, 2023) |
| "The treatment of epilepsy is associated with the inhibition of γ-aminobutyric acid-aminotransferase (GABA-AT), which suppresses the concentration of a key neurotransmitter GABA." | ( Akshinthala, P; Kapavarapu, R; M, AR; Salaria, P, 2023) |
| "Epilepsy is a chronic disease characterized by an ongoing predisposition to seizures." | ( Coitinho, AS; de Lima Rosa, G; Domingues, AM; Guzzo, EFM; Padilha, RB, 2023) |
| "Epilepsy is a chronic disease of the central nervous system characterized by recurrent epileptic seizures." | ( Czuczwar, SJ; Kamieniak, M; Kośmider, K; Miziak, B, 2023) |
| "Epilepsy is a complex neurological disease characterized by spontaneous recurrent seizures that affect around 1% of the global population." | ( Jiang, X; Liu, J; Wang, Y, 2023) |
| "Epilepsy is the most common symptom in patients with brain tumors." | ( Aronica, E; Ciusani, E; Coppola, A; Costa, C; Maschio, M; Perversi, F; Russo, E; Salmaggi, A, 2023) |
| "Epilepsy is a chronic neurological condition in which inflammation and oxidative stress play a key role in the pathogenesis." | ( Dolatshahi, M; Hashemi, P; Karimpour, S; Nazarinia, D, 2023) |
| "Epilepsy is one of the most prevalent neurological illnesses defined by periodic seizures with or without loss of consciousness caused by aberrant neural activity." | ( Alhalmi, A; Bharadwaj, A; Kumar, G; Pathak, D; Sharma, A; Singh, T; Virmani, T, 2023) |
| "Epilepsy is highly prevalent in SSADHD, and its onset and severity correlate with an age-related decline in GABA and GABA-related metabolite levels as well as TMS markers of reduced cortical inhibition." | ( Arning, E; Aygun, D; Bertoldi, M; DiBacco, ML; García-Cazorla, À; Gibson, KM; Jeltsch, K; Lee, HHC; MacMullin, P; Opladen, T; Pearl, PL; Rotenberg, A; Roullet, JB; Sachee, D; Tokatly Latzer, I; Tsuboyama, M, 2023) |
| "Epilepsy is an important cause of morbidity and mortality especially in low- and middle-income countries." | ( Chhetri, B; Dhakal, GP; Dorji, T; Jamtsho, S; Nirola, DK; Pema, D; Tenzin, K; Wangmo, S, 2023) |
| "Epilepsy is one common brain disorder, which is not well controlled by current pharmacotherapy." | ( Chen, Z; Ji, XM; Jiang, XH; Liu, JY; Qiu, XY; Sun, MJ; Tan, B; Wang, F; Wang, Y; Xu, CL, 2023) |
| "Epilepsy is considered to result from an imbalance between excitation and inhibition of the central nervous system." | ( Gu, J; Guo, HK; Hu, DM; Huang, R; Ke, PY; Kwan, P; Liu, J; Ma, YL; Tang, FL; Zang, QW; Zhang, H; Zhang, XG; Zhang, ZJ, 2023) |
| "Epilepsy is a common neurological disease requiring long-term therapy also during pregnancy." | ( Beyersmann, J; Dathe, K; Fietz, AK; Hoeltzenbein, M; Onken, M; Schaefer, C; Slimi, S; Stegherr, R, 2023) |
| "Epilepsy is a common chronic neurological disorder in the pediatric population and its evolution can be fatal." | ( Bourrous, M; Gyamfi, SO; Lahmini, W, 2023) |
| "Epilepsy is a chronic brain disease and often occurs suddenly for no reason." | ( Li, HM; Li, XZ; Liu, Q; Yang, WD; Zhang, SN; Zhou, Y, 2023) |
| "Epilepsy is not well controlled by current anti-seizure drugs (ASDs)." | ( Chen, Z; Cho, WS; Dai, SJ; Li, ZS; Nishibori, M; Park, SB; Qiu, XY; Shao, YY; Shi, JY; Sun, JY; Wang, Y; Xu, CL; Yan, MQ; Yi, S; Zheng, Y, 2023) |
| "Epilepsy is one of the most common neurologic disorders globally." | ( Fazlollahi, A; Gharagozli, K; Golabi, B; Kolahi, AA; Nejadghaderi, SA; Safiri, S; Sullman, MJM; Zahmatyar, M; ZareDini, M, 2023) |
| "Epilepsy is widely investigated as a common neurological disease requiring pharmacologically effective agents." | ( Azak Pazarlar, B; Bilister Egilmez, C; Erbas, O; Erdogan, MA, 2023) |
| "Focal epilepsy is thought to be a network disease, in which epileptiform activity can spread noncontiguously through the brain via highly interconnected nodes, or hubs, within existing networks." | ( Estin, J; Li, D; Li, J; Lin, W; Liou, JY; Luo, P; Ma, H; Niemeyer, JE; Schwartz, TH; Yang, F; Zhan, F; Zhao, M, 2023) |
| "Epilepsy is a neurological disorder affecting both children and adults, and many aspects of this disease are still poorly understood." | ( D'Amora, M; De Angelis, F; Faraguna, U; Galgani, A; Giorgi, FS; Marchese, M; Tantussi, F, 2023) |
| "Epilepsy is a common chronic brain disease." | ( Chen, L; Cui, W; Huang, H; Luo, T; Xu, Z; Zhu, M, 2023) |
| "Epilepsy is one of the most common and serious brain syndromes and has adverse consequences on a patient's neurobiological, cognitive, psychological, and social wellbeing, thereby threatening their quality of life." | ( Liu, J; Xia, Z; Xie, C; Zhang, X; Zhao, W, 2023) |
| "Epilepsy is one of the most serious worldwide neurological disorders that lead to the cognitive-psychosocial insults in recurrent seizures." | ( Abdelaziz, EZ; Ali, DA; Kolieb, E; Mohamed, AM, 2023) |
| "Epilepsy is the most common chronic disorder in the nervous system, mainly characterized by recurrent, periodic, unpredictable seizures." | ( Huang, H; Luo, Y; Tai, Z; Xu, Z; Yang, J; Zhang, H; Zhang, L, 2023) |
| "Epilepsy is one of the most common neurologic diseases, and around 30% of all epilepsies, particularly the temporal lobe epilepsy (TLE), are highly refractory to current pharmacological treatments." | ( Bascuñana, P; Delgado, M; García-García, L; Gomez, F; Hernández-Martín, N; Pozo, MÁ; Rosa, RF; Silván, Á, 2023) |
| "Epilepsy is a nervous system disease that affects millions of individuals worldwide, and up to 25% of patients have seizures that are resistant to antiepileptic drugs." | ( Dogru, YZ; Erat, M; Nacar, T, 2023) |
| "Epilepsy is one of the most prevalent neurological human diseases, affecting 1% of the population in all age groups." | ( Challal, S; Crawford, AD; Esguerra, CV; Langlois, M; Skalicka-Woźniak, K; Skiba, A; Wolfender, JL, 2023) |
| "Epilepsy is one of the most common chronic neurological disorders, affecting more than 50 million people globally." | ( Abakumova, T; Hoyle, CHV; Ziganshina, LE, 2023) |
| "Epilepsy is marked by unpredictable and recurrent episodes of seizures." | ( Shende, P; Trivedi, R, 2023) |
| "Epilepsy is a prevalent disease that requires personalized care to control seizures, reduce side effects, and ameliorate the burden of comorbidities." | ( Funaro, MC; Khan, W; Moeller, JJ; Narrett, JA, 2023) |
| "Patients with epilepsy are significantly burdened by the disease due to long-term health risks, the severe side effect profiles of anti-epileptic drugs, and the strong possibility of pharmacoresistant refractory seizures." | ( Burkett, JP; Kile, KB; Lloyd, EAR; Neifer, AE; Neifer, KL; Swain, CC; Wischmeier, JN, 2023) |
| "Epilepsy is a complex neurological condition characterized by recurrent seizures." | ( Attisano, L; Carlen, PL; El Soufi El Sabbagh, D; Nader, G; Santos, AC; Urban, K, 2023) |
| "Epilepsy is a chronic brain disorder characterized by unprovoked and recurrent seizures, of which 60% are of unknown etiology." | ( Ameli, C; Cordero-Maldonado, ML; Crawford, AD; Donato, C; Martins, TG; Mombaerts, L; Peri, F; Skupin, A; Soliman, R, 2023) |
| "Epilepsy is a common neurological disease caused by synchronous firing of hyperexcitable neurons." | ( Chen, T; Gu, N; Ju, Y; Li, M; Lin, X; Liu, Y; Tang, J; Wang, X; Yang, F, 2023) |
| "Epilepsy is a group of neurological diseases characterized by susceptibility to recurrent seizures." | ( Harris, KM; Hope, OA, 2023) |
| "Epilepsy is a major symptom in patients with glioma." | ( Arakawa, Y; Furukawa, K; Hattori, EY; Kikuchi, T; Mineharu, Y; Miyamoto, S; Tanji, M; Terada, Y; Yamao, Y, 2023) |
| "Epilepsy is the most common neurological disorder which is accompanied with behavioral and psychiatric alternations." | ( Hashemi, P; Moslehi, A; Nazarinia, D, 2023) |
| "Epilepsy is caused by an excessive recurrent excitatory neuronal firing, characterized by motor, psychomotor, and sensory impairments." | ( Dhureja, M; Gupta, R; Kumar, P; Soni, D; Upadhayay, S, 2023) |
| "Epilepsy is one of the most common chronic neurological disorders, affecting around 50 million people worldwide, but its underlying cellular and molecular events are not fully understood." | ( Dzwonek, J; Grajkowska, W; Marchel, A; Matyja, E; Rysz, A; Skupien-Jaroszek, A; Szczepankiewicz, AA; Wilczynski, GM, 2023) |
| "Epilepsy is a neurological disease with high global prevalence." | ( Khoo, CS; Lim, KY; Rajah, R; Tajurudin, FW; Tan, HJ, 2023) |
| "Epilepsy is a serious neurological disorder characterised by a tendency to have recurrent, spontaneous, seizures." | ( Anderson, C; Bagshaw, AP; Cook, MJ; D'Souza, W; Lightman, SL; Marinelli, I; Seneviratne, U; Terry, JR; Walker, JJ; Woldman, W, 2023) |
| "Epilepsy is characterized by repeated seizure activity." | ( Kesavan, R; Kumar, RR; Narayan, SK; Ramakrishnan, K; Shewade, D; Venkatraman, S, 2023) |
| "Epilepsy is a prevalent neurological disease, affecting approximately 1-2% of the global population." | ( Benvenutti, R; Chitolina, R; Herrmann, AP; Linazzi, A; Marcon, M; Piato, A; Reis, CG; Stahlhofer-Buss, T, 2023) |
| "Pediatric epilepsy is a debilitating disease cluster that is much less researched than adult epilepsy." | ( Daniel, J, 2023) |
| "Epilepsy is a prevalent neurological disorder with a complex pathogenesis and unpredictable nature, presenting limited treatment options in >30 % of affected individuals." | ( Barbosa, RM; Fernandes, E; Gerhardt, GA; Ledo, A, 2024) |
| "Epilepsy is a chronic neurological disease with recurrent seizures." | ( Akyüz, E; Ateş, Ş; Doğanyiğit, Z; Okan, A; Shaikh, MF; Taheri, S; Yılmaz, S; Yılmaz, Z, 2023) |
| "Epilepsy is a neurological disorder characterized by recurrent seizures, partially correlated with genetic origin, affecting over 70 million individuals worldwide." | ( He, MF; Lin, YM; Liu, CQ; Mao, YL; Qiao, JD; Zhang, XX, 2023) |
| "Epilepsy is a chronic neurological condition that disrupts the normal functioning of the brain and it is characterized by seizures." | ( Amidu, SB; Boamah, VE; Ekuadzi, E; Mante, PK, 2023) |
| "Epilepsy is a very common neurological disease with high morbidity and mortality." | ( Cánovas-Iniesta, M; Navarro-Lozano, M; Palazón-Cabanes, B; Pérez-Navarro, VM, 2023) |
| Excerpt | Reference |
|---|
| "Carbamazepine (CBZ) used in the treatment of epilepsy, is metabolized in man to an active metabolite: carbamazepine 10-11 epoxide (CBZ-E)." | ( Bonneton, J; Genton, P; Mesdjian, E, 1992) |
| "Since they are usually under treatment for epilepsy, it is difficult to determine whether the absence of pain is due to these patients' epileptic condition or to its treatment, since most antiepileptic drugs also have analgesic effects." | ( Dano, P; Guieu, R; Mesdjian, E; Pouget, J; Roger, J; Serratrice, G, 1992) |
| "Two female patients, one treated for epilepsy by phenobarbital (PB) and carbamazepine (CBZ), the other suffering from neurosis and free of any drug therapy, were given group B vitamins (riboflavin and nicotinic acid respectively) and showed during the long-term administration of these vitamins 2-3 Hz generalized electro-encephalographic (EEG) abnormalities." | ( Albani, F; Gastaut, H; Gobbi, G; Santanelli, P, 1988) |
| "The introduction of bromide for the treatment of epilepsy was an important episode in the history of neurology, and the individual responsible for it is therefore deserving of special recognition." | ( Friedlander, WJ, 1986) |
| "The prevalence of treated epilepsy in Wellington is 4." | ( Johnson, RH; Lambie, DG; Stanaway, L, 1981) |
| "The medication regimens used to treat epilepsy are further complicated by the fact that most seizure medications are metabolized in the liver and have the potential for serious pharmacokinetic drug-drug interactions with many other medications." | ( Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR, 1995) |
| "Trends in treatment of epilepsy in an institution for handicapped patients with epilepsy were investigated in a retrospective longitudinal study." | ( May, T; Wohlhüter, M; Wolf, P, 1994) |
| "Gabapentin's potential role in the treatment of epilepsy also was assessed." | ( Andrews, CO; Fischer, JH, 1994) |
| "CLB appears to be a useful treatment for epilepsy as intermittent or short-term add-on therapy; but it should also be tried as long-term therapy in some situations, especially as add-on therapy for patients with refractory epilepsy, as add-on or monotherapy for patients with anxiety, or in some women in association with oral contraceptives." | ( Remy, C, 1994) |
| "As with all benzodiazepines used for treating epilepsy, sedation and withdrawal effects, together with the development of tolerance, limit its usefulness." | ( Schmidt, D, 1994) |
| "The latter 2 cases had been treated as epilepsy." | ( Ikeno, T; Nagai, H, 1993) |
| "All the children had treatment-resistant epilepsy and most had two or more seizure types." | ( Alving, J; Besag, FM; Dulac, O; Hosking, G; Spencer, SC; Wallace, SJ, 1995) |
| "For many years, the medical treatment of epilepsy was based on the use of the same few drugs, which were chosen according to the seizure type in a fairly standardized manner." | ( Bourgeois, BF, 1996) |
| "Carbamazepine, a drug used for the treatment of epilepsy and neuralgias, may exert hazardous effects on the cardiac conduction system." | ( Jiménez, JE; Johnson, CD; Rivera, H, 1997) |
| "Invasive or complex treatments for epilepsy with partial and generalized tonic-clonic seizures should not be used until at least two AEDs have failed to control seizures." | ( Camfield, CS; Camfield, PR; Dooley, JM; Gordon, K, 1997) |
| "Physicians treating epilepsy must be aware that CBZ can exacerbate seizures, and cause developmental regression in children." | ( Nagarajan, L; Prasad, AN; Stefanelli, M, 1998) |
| "The course of untreated epilepsy is not well established." | ( Arida, RM; Cavalheiro, EA; Peres, CA; Scorza, FA, 1999) |
| "In 1993, 27% of patients were being treated for epilepsy and in 1995/6, 30." | ( Carvill, S; Cassidy, G; Clarke, D, 1999) |
| "To most effectively treat children with epilepsy syndromes, further research must be completed to validate the positive effects described in case reports, open-label clinical trials, and early controlled clinical trials." | ( Pellock, JM, 1999) |
| "Surgical treatment of epilepsy should be considered an important alternative to medical therapy." | ( Bal, CS; Bhatia, M; Dash, HH; Gaekwad, S; Gupta, S; Jain, S; Maheshwari, MC; Padma, MV; Sarkar, C; Singh, VP, 1999) |
| "Surgical treatment of epilepsy is a safe, effective mode of therapy." | ( Bal, CS; Bhatia, M; Dash, HH; Gaekwad, S; Gupta, S; Jain, S; Maheshwari, MC; Padma, MV; Sarkar, C; Singh, VP, 1999) |
| "A test for an interaction between treatment and epilepsy type (partial versus generalized) was also undertaken." | ( Chadwick, DW; Clough, HE; Hutton, JL; Marson, AG; Williamson, PR, 2000) |
| "The test for an interaction between treatment and epilepsy type was non significant for time to treatment withdrawal and 12 month remission, but significant for time to first seizure." | ( Chadwick, DW; Clough, HE; Hutton, JL; Marson, AG; Williamson, PR, 2000) |
| "A 57-year-old woman was under treatment for epilepsy with lamotrigine 2 mg/kg/d since 1996." | ( Cazzola, M; Muzzupappa, S; Panni, B; Sarzi-Puttini, P; Turiel, M, 2000) |
| "When discussing the treatment of epilepsy, targeted populations need to be defined." | ( Leppik, IE, 2001) |
| "Locock introduced bromide in the treatment of epilepsy in 1857." | ( Lund, M, 1997) |
| "Ideally any pregnancy in a woman being treated for epilepsy should be planned, and both an obstetrician and a neurologist should be consulted." | ( Barcik, U; Bourgeois, M; El Ghouzzi, V; Lajeunie, E; Renier, D; Thorne, JA, 2001) |
| "are used for the treatment of epilepsy by traditional healers in subcontinent." | ( Choudhary, MI; DeLorenzo, RJ; Rahman, AU; Raza, M; Shaheen, F; Sombati, S, 2002) |
| "Pharmacological treatment of epilepsy is needed whenever epilepsy occurs." | ( Artigas-Pallarés, J; Brun-Gasca, C, 2001) |
| "Both the vigabatrin treated epilepsy group and conventionally treated epilepsy group exhibited significantly reduced POBF (p=<0." | ( Embleton, SJ; Gupta, AK; Hosking, SL; Roff Hilton, EJ, 2003) |
| "The safety and efficacy of treatment with antiepilepsy drugs combined with methylphenidate were determined by assessing seizure frequency, changes in ADHD symptoms, the Conners' Rating Scales, EEG differences, and side effects." | ( Erdemoglu, AK; Gucuyener, K; Kockar, AI; Senol, S; Serdaroglu, A; Soysal, S, 2003) |
| "Valproate is used widely for the treatment of epilepsy but has been associated with hyperandrogenism, hyperinsulinemia, and dyslipidemia." | ( Ayala, R; Dam, M; Gomez, G; Isojärvi, J; Messenheimer, J; Morrell, MJ; O'Neill, F; Taylor, AE; Tennis, P, 2003) |
| "The utility of vigabatrin in the treatment of epilepsy is partially offset by its retinal toxicity." | ( Frisén, L, 2004) |
| "The VPA-treated girls with epilepsy had normal serum T4 and FT4 concentrations, but slightly increased TSH levels (3." | ( Isojärvi, JI; Knip, M; Mikkonen, K; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Vainionpää, LK, 2004) |
| "The average annual cost of outpatient treatment of epilepsy was found to be 47 US dollars per patient." | ( Kapoor, SK; Krishnan, A; Sahariah, SU, 2004) |
| "We describe the incidence of newly treated epilepsy in primary care and patterns of antiepileptic drug prescription, numbers of patients who remain on initial therapy and health service utilisation." | ( Buchan, S; Kerr, MP; Morgan, CL, 2004) |
| "Manipulation of neurosteroids to treat epilepsy has been an area of active research." | ( Harden, C; MacLusky, NJ, 2005) |
| "The use of VPA in the treatment of epilepsy is not associated with visual field defects similar to vigabatrin, but may induce abnormalities in colour vision." | ( Kälviäinen, R; Mäntyjärvi, M; Rissanen, E; Sorri, I, 2005) |
| "Physicians with basic training could treat epilepsy patients with phenobarbital, with beneficial effects for most patients with convulsive seizures." | ( Bell, GS; Dai, XY; de Boer, HM; Hong, Z; Ma, GY; Prilipko, L; Sander, JW; Wang, TP; Wang, WZ; Wu, JZ; Yang, B; Yuan, CL, 2006) |
| "On pharmacological treatment of epilepsy in people with intellectual disabilities, there were two articles on topiramate and one on levetiracetam." | ( Huber, B; Seidel, M, 2006) |
| "The current treatment of epilepsy focuses exclusively on the prophylaxis or suppression of seizures and thus provides merely a symptomatic treatment, without clear influence on the course of the disease." | ( Brandt, C; Heile, A; Löscher, W; Potschka, H; Stoehr, T, 2006) |
| "Agents introduced for the treatment of epilepsy have also been usedsimultaneously for psychiatric indications." | ( Bidzan, L, 2006) |
| "The aim of drug treatment for epilepsy is to prevent seizures without causing adverse effects." | ( Dahl, ML; Kimland, E; Tomson, T, 2007) |
| "In the melatonin-treated epilepsy plus Px group, the number of TUNEL positive cells decreased significantly compared to both epilepsy and epilepsy plus Px groups; however, there was no statistically significant difference from the control groups as a result of melatonin activity." | ( Ateş, U; Baka, M; Turgut, M; Uyanikgil, Y; Yavaşoğlu, A; Yurtseven, M, 2007) |
| "The development of novel treatments for epilepsy in TSC would benefit greatly from a suitable animal model, but most animal models of TSC to date have few reported neurological abnormalities, such as epilepsy." | ( Erbayat-Altay, E; Gutmann, DH; Wong, M; Xu, L; Zeng, LH, 2007) |
| "Currently, the trend is to treat patients with epilepsy with ER formulations because of the better compliance, convenience and flat plasma concentration versus time curve." | ( Bialer, M, 2007) |
| "The clinic treatment of epilepsy with epileptic foci overlapped with eloquent cortex is not satisfactory." | ( Gao, GD; Guo, H; Jing, XR; Wang, HW; Yao, QH; Zhang, H, 2008) |
| "Thirty untreated epilepsy patients were randomly divided into two groups receiving TPM or VPA, respectively." | ( Sun, W; Wang, W; Wang, Y; Wu, X, 2008) |
| "Vigabatrin was a major drug in the treatment of epilepsy until the discovery that it was associated with an irreversible constriction of the visual field." | ( Craft, CM; Duboc, A; Dubus, E; Gong, J; Jammoul, F; Picaud, S; Sahel, JA; Simonutti, M; Wang, QP; Ye, W, 2008) |
| "Women with untreated epilepsy are more likely to have irregular menstrual cycles than are nonepileptic controls, indicating that the disease itself plays a role in the etiology of these reproductive abnormalities." | ( Hayes, FJ; Joffe, H, 2008) |
| "Phenytoin (PHT) is widely used to treat epilepsy in elderly patients, but information on its pharmacokinetics in this population is limited." | ( Ahn, JE; Birnbaum, AK; Brundage, RC; Cloyd, JC; Conway, JM; Leppik, IE; Marino, SE; Musib, LC; Ramsay, RE; Rarick, JO; White, JR, 2008) |
| "For these reasons, pharmacological treatment of epilepsy that might also confer antidepressant effects may be particularly beneficial in older patients." | ( Fakhoury, TA; Hammer, AE; Miller, JM; Vuong, A, 2008) |
| "Our studies find that topiramate treatment in epilepsy children increases energy metabolism, resulting in weight loss." | ( Feng, JH; Gao, F; Li, HF; Xia, ZZ; Yang, CW; Zou, Y, 2009) |
| "For the treatment of epilepsy there is no generally accepted treatment algorithm, as individual epilepsy centers follow different diagnostic and therapeutic guidelines." | ( Jobst, BC, 2009) |
| "Most current treatments for epilepsy are symptomatic therapies that suppress seizures but do not affect the underlying course or prognosis of epilepsy." | ( Wong, M, 2010) |
| "Topiramate is licensed for the treatment of epilepsy and for migraine prophylaxis, but is also used off-licence for a wide range of indications." | ( Marson, AG; Mirza, N; Pirmohamed, M, 2009) |
| "P is being evaluated as a treatment for epilepsy, traumatic brain injury, and other complex neurological conditions." | ( Briyal, S; Gangisetty, O; Reddy, DS, 2010) |
| "Two cohorts of patients with valproate-treated epilepsy and sex- and age-matched individuals (controls) from the general Danish population were identified by individual-level-linkage of nationwide registries and followed for 10 years." | ( Abildstrøm, SZ; Andersson, C; Erdal, J; Gislason, GH; Hansen, PR; Olesen, JB; Schmiegelow, M; Torp-Pedersen, C; Weeke, P, 2011) |
| "Medical treatment of epilepsy is quite different for women than for men." | ( Chiba, S, 2011) |
| "Approximately one third of newly treated epilepsy patients do not respond to antiepileptic drugs (AEDs)." | ( Haerian, BS; Lim, KS; Mohamed, EH; Mohamed, Z; Raymond, AA; Tan, CT; Tan, HJ; Wong, CP; Wong, SW, 2011) |
| "Although bromide (Br) is used to treat intractable epilepsy, serum Br concentrations are not routinely analyzed." | ( Fukuda, M; Ishii, E; Kikuchi, C; Motoki, T; Ohmori, H; Okamoto, K; Suemaru, K; Suzuki, Y; Wakamoto, H, 2011) |
| "(Passifloraceae) has been used for the treatment of epilepsy in several traditional systems of medicine." | ( Goel, RK; Singh, B; Singh, D, 2012) |
| "Our findings may have implications for treatment of epilepsy in female patients." | ( Aurlien, D; Gjerstad, L; Larsen, JP; Taubøll, E, 2012) |
| "Bacopa monnieri and Bacoside-A treatment reverses epilepsy associated changes to near control suggesting that decreased GABA receptors in the cerebral cortex have an important role in epileptic occurrence; Bacopa monnieri and Bacoside-A have therapeutic application in epilepsy management." | ( Abraham, PM; Antony, S; Balakrishnan, S; Mathew, J; Paulose, CS, 2012) |
| "Phenobarbital is an effective treatment for epilepsy but concerns remain over its potential neurocognitive toxicity." | ( Bell, GS; de Boer, HM; Ding, D; Hong, Z; Kwan, P; Li, S; Lin, W; Sander, JW; Sun, J; Thompson, PJ; Wang, W; Wu, J; Wu, Q; Yu, P; Zhang, Q; Zhao, Q; Zhou, D, 2012) |
| "He had been on a lamotrigine treatment due to epilepsy, and after cessation of lamotrigine, his cardiac enzyme levels returned to normal." | ( Bayhan, T; Karagöz, T; Sahin, M; Yıldırım, I, 2012) |
| "Subsequently, others using the drug to treat epilepsy failed to obtain the degree of benefit that the reports of Locock's comments would have led them to expect." | ( Eadie, MJ, 2012) |
| "For this reason, novel approaches to treat epilepsy are highly needed." | ( Kokaia, M; Sørensen, AT, 2013) |
| "Despite the use in treatment of epilepsy since 1924, the clinical efficacy was not demonstrated in a controlled, randomized trial until 2008, showing its capability of reducing seizure frequency with more than 50%." | ( Korsholm, K; Law, I, 2013) |
| "One indirect pathway for the treatment of epilepsy includes the inhibition of carbonic anhydrase (CA), thereby increasing CO(2) levels in the brain." | ( Aggarwal, M; Kondeti, B; McKenna, R, 2013) |
| "Therefore, we tried to use GA to treat PTZ-induced epilepsy rats." | ( Bai, H; Liu, Z; Meng, F; Xu, R; You, Y; Zhang, H; Zhao, Y, 2013) |
| "Valproate is used for the treatment of epilepsy and other neuropsychological disorders and may be the only treatment option for women of childbearing potential." | ( Christensen, J; Grønborg, TK; Parner, ET; Pedersen, LH; Schendel, D; Sørensen, MJ; Vestergaard, M, 2013) |
| "Early treatment of epilepsy is warranted to avoid possible severe consequences." | ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Long-term untreated epilepsy may expose to accident proneness and further psychiatric deterioration." | ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "The ultimate treatment goal in epilepsy therapy is always freedom from seizures with as few treatment adverse effects as possible." | ( Ben-Menachem, E, 2014) |
| "Medical treatment of epilepsy is quite different for women than for men." | ( Chiba, S; Yoshizawa, M, 2014) |
| "To explore a possible link between the treatment of AD and epilepsy, the molecular interactions of recently Food and Drug Administration approved antiepileptic drug Aptiom (Eslicarbazepine acetate) with BACE and VSC were studied." | ( Biswas, D; Hameed, N; Kamal, MA; Khan, M; Rizvi, SM; Shaikh, S; Shakil, S, 2014) |
| "Mitchell had distinct opinions on the treatment of epilepsy, and helped to advance its therapeutics during his career." | ( Boes, CJ; Burkholder, DB, 2014) |
| "Neurologists treating epilepsy continued to be more likely to prescribe folate (86." | ( Cavitt, J; Moseley, BD; Privitera, M; Sharma, A, 2015) |
| "Its role in the treatment of epilepsy in individuals with tuberous sclerosis complex (TSC) has yet to be determined." | ( Belt, OD; Geffrey, AL; Paolini, JL; Thiele, EA, 2015) |
| "The development of new drugs for the treatment of epilepsy is a major challenge for modern neurology and its first steps demand basic research." | ( Cambiaghi, M; Cursi, M; Magri, L, 2015) |
| "We asked all pediatric neurologists treating pediatric epilepsy in Finland if they had seen patients with pyridoxine-responsive infantile epilepsy." | ( Gaily, E; Mankinen, K; Riikonen, R, 2015) |
| "Lamotrigine (LTG) is used to treat epilepsy." | ( Hirai, K; Imai, K; Inoue, K; Inoue, Y; Itoh, K; Suzuki, E; Takahashi, T; Takahashi, Y; Tsuji, D; Umemura, A; Yamamoto, Y, 2016) |
| "Use of LCM to treat children with epilepsy has been supported by multiple studies with limited information on iv use in children." | ( Arkilo, D; Gustafson, M; Ritter, FJ, 2016) |
| "An unmet need in the treatment of epilepsy has been targeted therapies that prevent the onset or progression of seizures in the susceptible individual." | ( Jeong, A; Wong, M, 2016) |
| "Successful treatment of the epilepsy may alleviate anxiety symptoms." | ( Brandt, C; Mula, M, 2016) |
| "Cannabis has been associated with the treatment of epilepsy throughout history, and if ancient Assyrian sources referring to "hand of ghost" are considered credible, this relationship may span four millennia." | ( Russo, EB, 2017) |
| "The use of cannabis products in the treatment of epilepsy has long been of interest to researchers and clinicians alike; however, until recently very little published data were available to support its use." | ( Friedman, D; Gaston, TE, 2017) |
| "In spite of recent advances in the treatment of epilepsy, up to 35% of people living with the condition do not respond to accessible anti-epileptic drugs (AEDs) and continue to experience regular, devastating and potentially life-threatening seizures." | ( Asadi-Shekaari M, M; Esmaeili-Mahani, S; Kalantaripour, TP; Najafipour, H; Sheibani, V, 2017) |
| "Use of perampanel for the treatment of epilepsy was associated with significant reduction in all-cause and epilepsy-related health care resource utilization, including hospitalizations, especially for status epilepticus, and outpatient visits." | ( Barghout, V; Choi, J; Duh, MS; Faught, E; Germain, G; Haider, B; Laliberté, F; Lejeune, D; Wagh, A; Wang, Z, 2017) |
| "Presently, treatment of epilepsy is palliative in nature, providing only symptomatic relief to patients." | ( Jamwal, S; Koshal, P; Kumar, P, 2018) |
| "The ESL group was all patients with treatment-resistant epilepsy who developed intolerable PBSEs to LEV, subsequently trialed on ESL." | ( Ahmed, A; Henley, W; Jalihal, V; McLean, BN; Parrett, M; Sander, JW; Shankar, R; Tittensor, P, 2018) |
| "Twenty-one CSWS patients treated for epilepsy from January 2006 to December 2016 in Pediatric Department of Peking University First Hospital were enrolled into the study." | ( Bian, KG; Gong, P; Liu, XY; Qian, P; Xue, J; Yang, HP; Yang, ZX, 2018) |
| "Although some drugs used in the treatment of epilepsy are known to affect body weight, the hormonal factors responsible have not been sufficiently described." | ( Alver, A; Cansu, A; Çiçek, NP; Kamaşak, T; Okten, A; Serin, M, 2018) |
| "Carbamazepine (CBZ) is used for the treatment of epilepsy and other neurological and psychiatric disorders." | ( Fricke-Galindo, I; Jung-Cook, H; LLerena, A; López-López, M, 2018) |
| "Valproic acid (VPA) provides a common treatment for both epilepsy and bipolar disorder; however, common cellular mechanisms relating to both disorders have yet to be proposed." | ( Kelly, E; Sharma, D; Wilkinson, CJ; Williams, RSB, 2018) |
| "Future research strategies for new drug treatments in epilepsy will probably take comorbidities into account." | ( Mula, M, 2018) |
| "Patients with onset of AED-treated epilepsy after stroke in 2005-2010 were included." | ( Åsberg, S; Kumlien, E; Larsson, D; Zelano, J, 2019) |
| "Neurotrophic factors are candidates for treating epilepsy, but their development has been hampered by difficulties in achieving stable and targeted delivery of efficacious concentrations within the desired brain region." | ( Barbieri, M; Bell, WJ; Emerich, DF; Falcicchia, C; Fradet, T; Kokaia, M; Lovisari, F; Paolone, G; Simonato, M; Wahlberg, LU, 2019) |
| "Antiepileptic drugs are the mainstream treatment for epilepsy; however, the drug resistance occurring in 20-30% of patients and side effects of available medications have resulted in a search for natural remedies that can support disease therapy." | ( Andres-Mach, M; Bryda, J; Szewczyk, A; Zagaja, M, 2019) |
| "Na+ channel blockers in the treatment of SCN8A epilepsy may correlate with the effect of such agents on pathological Na+ current observed in heterologous systems." | ( Abou Tayoun, A; Goldberg, EM; Zaman, T, 2019) |
| "In India, it is used for the treatment of epilepsy as traditional medicine." | ( Dinda, AK; Kaleekal, T; Katyal, J; Pattnaik, SS; Sarangi, SC, 2020) |
| "We reviewed records of patients treated for epilepsy due to posterior reversible encephalopathy syndrome after liver transplant seen at our pediatric neurology clinic between January 2010 and March 2019." | ( Akdur, A; Balcı Sezer, O; Haberal, M; Özçay, F; Sezer, T; Torgay, A, 2020) |
| "The drugs currently available for treating epilepsy are only partially effective in managing this condition." | ( Dukhinova, M; Kopeikina, E; Kuznetsova, IS; Lau, TYB; Levchuk, K; Ponomarev, ED; Veremeyko, T; Yung, AWY, 2020) |
| "To study the efficacy of reamberin in treatment of epilepsy in children and to evaluate its effect on the antioxidant status." | ( Dorovskikh, VA; Nosal', LA; Shtarberg, MA; Simonova, NV, 2019) |
| "It is successfully used in treatment of epilepsy for 30 years." | ( Belova, YA; Kotov, AS; Romanova, MV; Rudakova, IG, 2019) |
| "In addition to medical treatment, epilepsy surgery may be offered to drug-resistant patients but carries a high risk of relapse of herpetic encephalitis." | ( Chipaux, M; Delalande, O; Dorfmuller, G; Ferrand-Sorbets, S; Fohlen, M; Maurey, H; Petrescu, A; Taussig, D, 2020) |
| "This study provided children with treatment-resistant epilepsy (TRE) access to plant-derived highly purified cannabidiol (CBD; Epidiolex® in the US; Epidyolex® in the EU; 100 mg/mL oral solution)." | ( Diamond, MP; Flamini, JR; Linder, DF; Long, SA; Moretz, K; Park, YD; Pope, J, 2020) |
| "Thirty-nine patients with treatment-resistant epilepsy completed the study protocol, i." | ( Geiger, MJ; Hirsch, M; Klotz, KA; Metternich, B; Schulze-Bonhage, A; Wagner, K, 2021) |
| "To study the efficacy of reamberin in treatment of epilepsy in children and to evaluate its effect on the cognitive functions." | ( Dorovskikh, VA; Nosal', LA; Simonova, NV, 2020) |
| "Rhynchophylline target genes to treat epilepsy were identified using PharmMapper, SwissTargetPrediction and DrugBank databases integration." | ( Chen, X; Geng, H; Wang, C, 2021) |
| "Twenty-two days after tacrolimus treatment, epilepsy occurred." | ( Mo, Y; Ren, R; Wang, F; Yang, Y; Zhang, L, 2021) |
| "Valproic acid, a first-line drug to treat epilepsy, is associated with serious side effects, which precludes its wider use." | ( Gao, M; Qu, K; Wang, X; Zhang, W, 2021) |
| "Cannabis has been used to treat epilepsy for millennia, with such use validated by regulatory approval of cannabidiol (CBD) for Dravet syndrome." | ( Absalom, NL; Anderson, LL; Arnold, JC; Bahceci, D; Benson, MJ; Bowen, MT; Chebib, M; Doohan, PT; Hawkins, NA; Heblinski, M; Kearney, JA; McGregor, IS; Zhang, F, 2021) |
| "OV329, a novel drug candidate for the treatment of epilepsy and addiction, has been shown in vitro to be substantially more potent as a GABA-AT inactivator than vigabatrin, an antiseizure drug approved as an add-on therapy for adult patients with refractory complex partial seizures and monotherapy for pediatric patients with infantile spasms." | ( Deking, LS; During, MJ; Feja, M; Gernert, M; Kaczmarek, E; Meller, S; Silverman, RB, 2021) |
| "Valproic acid (VPA) is used for the treatment of epilepsy and bipolar disorder (BD)." | ( Hsieh, TC; Lin, CC; Wu, LS, 2022) |
| "We included beneficiaries with newly treated epilepsy (International Classification of Diseases codes for epilepsy/convulsions 2014-2017, no ASM in the previous 2 years)." | ( Burke, JF; Choi, H; Terman, SW; Youngerman, BE, 2022) |
| "Valproate (VPA) is an effective treatment for epilepsy and also used in bipolar disorder." | ( Eriksson, SH; Sisodiya, SM; Tittensor, P, 2022) |
| "We evaluated everolimus in 14 treatment resistant epilepsy patients undergoing surgical resection (4." | ( Askenazi, M; Devinsky, O; Devore, S; Friedman, D; Jones, D; Kanshin, E; Leitner, DF; Siu, Y; Ueberheide, B; Wisniewski, T, 2022) |
| "LEV seems as a rational drug for treatment of epilepsy patients, particularly for those with osteoporosis, since the comparative results of one year and longer than 5-years usage data did not show any statistically significant difference." | ( Aydın, Z; Gözükızıl, ST; Yalçın, AD, 2022) |
| "Currently, the treatment for epilepsy includes the administration of drugs or surgery, but about 30% of the patients treated with antiepileptic drugs develop time-dependent pharmacoresistence." | ( Belperio, G; Corso, C; Duarte, CB; Mele, M, 2022) |
| "The outcome was the development of treatment resistant epilepsy (TRE), defined as having at least three distinct antiseizure medications in 1 year." | ( Cepeda, MS; Kern, DM; Novak, G; Teneralli, RE, 2022) |
| "CBD is a recognized novel treatment for epilepsy." | ( Castro, LHM; Oshiro, CA, 2022) |
| "Both the prevalence of treatment for epilepsy and of treatment for psychosis was 0." | ( Bakken, IJ; Bråthen, G; Brodtkorb, E; Landmark, CJ; Morken, G; Revdal, E, 2022) |
| "In the histopathological examination of treatment-resistant epilepsy, focal cortical dysplasia (FCD) is the most common diagnosis in the pediatric group." | ( Bilgic, B; Dolgun, M; Gurkan, ZM; Gürses, C; Kapar, O; Sencer, A, 2022) |
| "Pharmacologic treatment of epilepsy in pregnant women is balancing between risks for the mother and fetus." | ( Edens, M; Schelhaas, M; Ter Horst, P; Touw, D; Wammes-Van Der Heijden, E; Wegner, I, 2023) |
| "Most comparative studies focusing on treatment of epilepsy in older adults have found that levetiracetam has the best chance of long-term seizure freedom." | ( Akamatsu, N; Beghi, E; Costa, C; Cretin, B; Dhakar, MB; DiFrancesco, JC; Faught, E; Giussani, G; Krämer, G; Kwan, P; Leppik, I; O'Dwyer, R; Piccenna, L, 2023) |
| "Topiramate (TPM) is effective for treating epilepsy, but executive dysfunction is a common side effect that could significantly affect everyday life." | ( Elger, CE; Hansen, N; Helmstaedter, C; von Wrede, R; Widman, G; Witt, JA, 2022) |
| "Pharmacotherapy is the main treatment for epilepsy, but at least 30% of patients with epilepsy have pharmacoresistant epilepsy." | ( Chou, IC; Wang, HS; Yang, MT, 2023) |
| "Effective treatment of epilepsy is a major challenge in the field of neurology." | ( Alyan NajafAbadi, S; Maghbooli, M; MalekMahmoudi, G; Molseghi, MH, 2023) |
| "Difficult-to-treat epilepsy related to conditions including tuberous sclerosis complex (TSC), Lennox Gastaut syndrome (LGS) and Dravet syndrome (DS) have been the target of recent developments." | ( Klein, P; Pong, AW; Xu, KJ, 2023) |
| "Medicinal treatment against epilepsy is faced with intractable problems, especially epileptogenesis that cannot be blocked by clinical antiepileptic drugs (AEDs) during the latency of epilepsy." | ( Chen, Q; Fan, H; Guo, Y; Jiang, C; Li, K; Liu, P; Sun, T; Zhou, Z, 2023) |
| "Patients with WHS who were treated for epilepsy at the Saitama Children's Medical Center under 5 years of age were included." | ( Daida, A; Hamano, SI; Hirata, Y; Horiguchi, A; Kikuchi, K; Koichihara, R; Matsuura, R; Nonoyama, H; Oba, D; Ohashi, H, 2023) |
| "However, the efficacy of perampanel treatment in epilepsy patients younger than 4 years has been less documented." | ( Handy, MJ; Hashimoto, K; Ito, Y; Jensen, FE; Roberts, NS; Talos, DM, 2023) |
| "Levetiracetam (LEV), clinically used to treat epilepsy, may have pro-cognitive effects by restoring balance to neuronal signalling." | ( Botha, TL; Brouwer, G; Finger-Baier, K; van der Westhuizen, C; Wolmarans, W, 2023) |
| "ZNS may be available to treat idiopathic epilepsy in cats." | ( Maeda, S; Motegi, T; Yonezawa, T; Yoshida, S, 2023) |
| "Moreover, DMF treatment reversed epilepsy-induced behavioral deficits in the treated rats." | ( Deeb, L; Guignet, M; Saadi, A; Sandouka, S; Sheeni, Y; Shekh-Ahmad, T; Singh, PK; Taiwo, RO; White, SH; Zhang, T, 2023) |