An organic heterotetracyclic compound that consists of an indole moiety ortho-fused to any benzazepine.
ChEBI ID: 138606
| Member | Definition | Role |
|---|---|---|
| nsc 664704 | An indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta). | kenpaullone |
| paullone | An indolobenzazepine that is 5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine carrying an oxo substituent at position 6. | paullone |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (2.75) | 18.2507 |
| 2000's | 31 (28.44) | 29.6817 |
| 2010's | 59 (54.13) | 24.3611 |
| 2020's | 16 (14.68) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 9 (7.56%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 110 (92.44%) | 84.16% |