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diastereoisomeric mixture
A mixture composed of two or more diastereoisomers (stereoisomers not related as mirror images).
ChEBI ID: 60915
Members (4)
Member | Definition | Role |
---|---|---|
alloin | A diastereoisomeric mixture of aloin A (barbaloin) and aloin B (isobarbaloin), which have similar properties. It is a bitter-tasting, yellow-brown colored compound found in the exudate of at least 68 Aloe species at levels of up to 6.6% of leaf dry weight (making between 3% and 35% of the total exudate), and in another 17 species at indeterminate levels. It is used as a stimulant-laxative, treating constipation by inducing bowel movements. | aloin |
amrubicinol | A diastereoisomeric mixture resulting from the formal reduction of the acetyl group at position 9 of amrubicin to the corresponding 1-hydroxyethyl group. The active metabolite of amrubicin in lung cancer patients. | amrubicinol |
buthionine sulfoximine | A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl. | 2-amino-4-(S-butylsulfonimidoyl)butanoic acid; S-butyl-DL-homocysteine (S,R)-sulfoximine |
golgicide a | A diastereoisomeric mixture comprising racemic cis- and racemic trans-goglioside A in a 10:1 ratio. It is a potent and rapidly reversible GBF1 (Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1) inhibitor. The (3aS,4R,9bR) isomer is the most active (see Bioorg. Med. Chem. Lett., 2012, 22, 5177-5181). | golgicide A |
Research
Studies (2,574)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 328 (12.74) | 18.7374 |
1990's | 912 (35.43) | 18.2507 |
2000's | 743 (28.87) | 29.6817 |
2010's | 487 (18.92) | 24.3611 |
2020's | 104 (4.04) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 13 (0.49%) | 5.53% |
Reviews | 36 (1.35%) | 6.00% |
Case Studies | 4 (0.15%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 2,606 (98.01%) | 84.16% |