Any compound that inhibits collagen cross-linking.
ChEBI ID: 91085
| Member | Definition | Class |
|---|---|---|
| aminopropionitrile | An aminopropionitrile carrying an amino group at the beta-position. | beta-aminopropionitrile |
| beta-aminopropionitrile fumarate (2:1) | A fumarate salt prepared from beta-aminopropionitrile by reaction of one molecule of fumaric acid for every two molecules of beta-aminopropionitrile. | beta-aminopropionitrile hemifumarate |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 580 (63.81) | 18.7374 |
| 1990's | 98 (10.78) | 18.2507 |
| 2000's | 53 (5.83) | 29.6817 |
| 2010's | 117 (12.87) | 24.3611 |
| 2020's | 61 (6.71) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 4 (0.42%) | 5.53% |
| Reviews | 38 (3.97%) | 6.00% |
| Case Studies | 2 (0.21%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 914 (95.41%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| arylsulfatase A | Homo sapiens (human) | Potency | 0.7569 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 23.0999 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 7.4978 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 0.7519 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 79.4328 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 0.5650 | 13 | 13 |
| Lysyl oxidase homolog 2 | Mus musculus (house mouse) | IC50 | 0.1280 | 1 | 1 |
| Lysyl oxidase homolog 2 | Rattus norvegicus (Norway rat) | IC50 | 0.1270 | 1 | 1 |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | IC50 | 0.2400 | 2 | 2 |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Bos taurus (cattle) | IC50 | 1.9953 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 33.7000 | 3 | 3 |