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dihydrochalcones

Any ketone that is 1,3-diphenylpropanone and its derivatives obtained by substitution.

ChEBI ID: 71230

Members (14)

MemberDefinitionRole
2',6'-dihydroxy-4'-methoxydihydrochalconeA member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 2' and 6' and a methoxy group at position 4' respectively.2',6'-dihydroxy-4'-methoxydihydrochalcone
3-(4-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-1-phenyl-1-propanone3-(4-methoxyphenyl)-3-(4-methylphenyl)sulfonyl-1-phenyl-1-propanone
3-(benzenesulfonyl)-3-(4-methoxyphenyl)-1-phenyl-1-propanone3-(benzenesulfonyl)-3-(4-methoxyphenyl)-1-phenyl-1-propanone
asebogeninA member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin.asebogenin
aspalathinA member of the class of dihydrochalcones that is the 2-C-beta-D-glucopyranide of phloroglucinol and which is substituted at position 4 by a 3-(3,4-dihydroxyphenyl)propanoyl group. A metabolite of red bush, Aspalathus linearis (and present in the herbal tea made from the leaves), aspalathin exhibits significant hypoglycemic activity.aspalathin
avobenzoneavobenzone
davidigeninA member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', and 4' respectively.davidigenin
dihydrochalconeA member of the class of dihydrochalcones that is acetophenone in which one of the hydrogens of the methyl group is replaced by a benzyl group.dihydrochalcone
dihydroxanthohumolA member of the class of dihydrochalcones that is the alpha,beta-dihydro derivative of xanthohumol. Isolated from Humulus lupulus, it exhibits inhibition of NO production.dihydroxanthohumol
neohesperidin dihydrochalconeA member of the dihydrochalcones that is 3,2',4',6'-tetrahydroxy-4-methoxydihydrochalcone attached to a neohesperidosyl residue at position 4' via glycosidic linkage. It is found in sweet orange.neohesperidin dihydrochalcone
phloretinA member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'.phloretin
phlorhizinAn aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2' via a glycosidic linkage.phlorizin
trilobatinAn aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. It is isolated from the leaves of the Chinese sweet tea Lithocarpus polystachyus and exhibits significant anti-hyperglycemic, anti-oxidative and anti-inflammatory properties.trilobatin
uvaretinA member of the class of dihydrochalcones that is 1,3-diphenylpropan-1-one in which the phenyl group that is bonded to the carbonyl group is substituted by hydroxy groups at positions 2 and 4, an o-hydroxybenzyl group at position 3, and a methoxy group at position 6. A cytotoxic natural product found particularly in Uvaria acuminata and Uvaria chamae.uvaretin

Research

Studies (3,173)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,434 (45.19)18.7374
1990's420 (13.24)18.2507
2000's450 (14.18)29.6817
2010's612 (19.29)24.3611
2020's257 (8.10)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials27 (0.75%)5.53%
Reviews110 (3.06%)6.00%
Case Studies10 (0.28%)4.05%
Observational0 (0.00%)0.25%
Other3,450 (95.91%)84.16%