Granulomatous Mastitis

A rare, benign, inflammatory breast disease occurring in premenopausal women shortly after a recent pregnancy. The origin is unknown but it is commonly mistaken for malignancy and sometimes associated with BREAST FEEDING and the use of ORAL CONTRACEPTIVES.

Synonym
Granulomatous Mastitis

Excerpt	Reference
"Granulomatous mastitis is a rare breast disease characterized by chronic inflammation."	( Bes, C; Sengul, N; Soy, M; Vardi, S; Yilmaz, F, 2010)
"Idiopathic granulomatous mastitis is an inflammatory mass in the breast."	( Karimifar, M; Mahzouni, P; Salesi, M; Salimi, F, 2011)
"Idiopathic granulomatous mastitis is a rare inflammatory breast disease of unknown etiology."	( Peña-Santos, G; Ruiz-Moreno, JL, 2011)
"Granulomatous mastitis is an uncommon chronic inflammatory breast condition that is characterized by granulomatous inflammation."	( Joseph, KA; Luu, X; Mor, A, 2014)
"Idiopathic granulomatous mastitis is an uncommon inflammatory disease of the non-lactating breast."	( Gopalakrishnan Nair, C; Jacob, P; Menon, RR, 2015)
"Idiopathic granulomatous mastitis is a distinct benign breast condition of unknown etiology but several triggers are suspected, including inflammatory, infectious, and hormonal factors."	( Gharib, M; Naderi, H; Sarvghad, M; Sheybani, F, 2015)
"Granulomatous mastitis is a very rare, chronic inflammatory disease and only ten patients with granulomatous mastitis with erythema nodosum and polyarthitis have been described."	( Abdulla, MC; Alungal, J; Narayan, R, 2016)
"Idiopathic granulomatous mastitis is a rare, benign inflammatory disease of breast."	( Çinar, M; Çolak, S; Tekgöz, E; Yilmaz, S, 2020)
"Idiopathic granulomatous mastitis is a rare inflammatory disease of the breast, for which there is a lack of consensus on the treatment protocol; it requires long-term follow-up and is associated with a high rate of relapse after surgical treatment."	( Duran, TI; Kehribar, DY; Ozgen, M; Polat, AK, 2020)
"Granulomatous mastitis is a rare inflammatory disease of varying etiology."	( Bauer, A; Gere, M; Hofmeyer, S; Nilsson, K; Tot, T, 2021)
"Granulomatous mastitis is a rare inflammatory disease of the breast, typically seen in woman of child-bearing age."	( Fakioglu, E; Ganguli, S; Laor, L, 2022)
"Idiopathic granulomatous mastitis is a benign, inflammatory disease of breasts characterized by non-caseating granulomas."	( Abbi, B; Ayesha, B; Fineberg, S; Gupta, A; Kumthekar, A; Lanjewar, S; Sanghavi, N; Xie, X, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	44 (53.01)	28.8240
2020's	39 (46.99)	9.53

Drug	Relationship Strength	Studies	Trials
formaldehyde	low	2	0
pyrazinamide	low	1	0
azathioprine	low	3	0
cefuroxime	low	1	0
ciprofloxacin	low	1	0
hydroxychloroquine	low	2	0
isoniazid	low	1	0
metronidazole	low	1	0
risperidone	low	3	0
sulpiride	low	1	0
prednisolone	medium	20	1
prednisone	low	13	0
methylprednisolone acetate	low	1	0
colchicine	low	2	0
triamcinolone acetonide	low	2	0
methylprednisolone	medium	7	2
hematoxylin	low	1	0
eosine yellowish-(ys)	low	1	0
gentian violet	low	2	0
ethambutol	low	1	0
ozone	low	3	0
trolamine salicylate	low	7	0
bromocriptine	low	4	0
triamcinolone	medium	3	1
calcium oxalate	low	1	0
amoxicillin	low	2	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	low	1	0
clarithromycin	low	1	0
methotrexate	low	25	0
levofloxacin	low	1	0
naproxen	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
mycophenolic acid	low	1	0
zithromax	low	1	0
mercaptopurine	low	1	0
clavulanic acid	low	1	0
desonide	medium	1	1
hypericum	low	1	0
interleukin-8	low	1	0
tetracycline	low	1	0
transforming growth factor beta	low	6	0
rifampin	low	2	0
clozapine	low	1	0

Protein Targets (742)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	12	0	0	12
Chain A, Beta-lactamase	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	9	0	0	9
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
AR protein	21	0	0	21
apical membrane antigen 1, AMA1	4	0	0	4
estrogen nuclear receptor alpha	27	0	0	27
Beta-lactamase	0	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	5	0	0	5
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
DNA polymerase kappa isoform 1	5	0	0	5
ATP-binding cassette sub-family C member 3	0	20	0	20
Multidrug resistance-associated protein 4	0	20	0	21
Bile salt export pump	0	10	0	10
Bile salt export pump	0	23	0	23
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase SHV-1	0	2	0	3
Cytochrome P450 2C9	0	7	0	8
Beta-lactamase	0	1	0	2
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Cytochrome P450 2J2	0	6	0	7
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	20	0	20
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
Chain A, Ferritin light chain	4	0	0	4
interleukin 8	4	0	0	4
acetylcholinesterase	7	0	0	7
thioredoxin reductase	12	0	0	12
phosphopantetheinyl transferase	6	0	0	6
RAR-related orphan receptor gamma	13	0	0	13
SMAD family member 2	7	0	0	7
ATAD5 protein, partial	9	0	0	9
Fumarate hydratase	5	0	0	5
SMAD family member 3	7	0	0	7
TDP1 protein	20	0	0	20
GLI family zinc finger 3	16	0	0	16
Microtubule-associated protein tau	7	0	0	8
thioredoxin glutathione reductase	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	11	0	0	11
EWS/FLI fusion protein	13	0	0	13
glucocorticoid receptor [Homo sapiens]	19	0	0	19
retinoic acid nuclear receptor alpha variant 1	13	0	0	13
retinoid X nuclear receptor alpha	12	0	0	12
estrogen-related nuclear receptor alpha	19	0	0	19
farnesoid X nuclear receptor	7	0	0	7
pregnane X nuclear receptor	15	0	0	15
G	8	0	0	8
polyprotein	5	0	0	5
P53	1	0	0	1
peroxisome proliferator-activated receptor delta	12	0	0	12
peroxisome proliferator activated receptor gamma	10	0	0	10
arylsulfatase A	4	0	0	4
IDH1	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
aryl hydrocarbon receptor	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
thyroid stimulating hormone receptor	6	0	0	6
activating transcription factor 6	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Histone H2A.x	9	0	0	9
Bloom syndrome protein isoform 1	6	0	0	6
peripheral myelin protein 22 isoform 1	4	0	0	4
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	6	0	0	6
thyroid hormone receptor beta isoform 2	13	0	0	13
heat shock protein beta-1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	14	0	0	14
geminin	15	0	0	15
peripheral myelin protein 22	7	0	0	7
survival motor neuron protein isoform d	8	0	0	8
cytochrome P450 3A4 isoform 1	9	0	0	9
M-phase phosphoprotein 8	3	0	0	3
muscleblind-like protein 1 isoform 1	6	0	0	6
muscarinic acetylcholine receptor M1	4	0	0	4
lamin isoform A-delta10	12	0	0	12
Gamma-aminobutyric acid receptor subunit pi	9	2	0	11
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Interferon beta	13	0	0	13
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Cellular tumor antigen p53	13	0	0	13
Gamma-aminobutyric acid receptor subunit beta-1	9	2	0	11
Gamma-aminobutyric acid receptor subunit delta	9	2	0	11
Gamma-aminobutyric acid receptor subunit gamma-2	9	2	0	11
Glutamate receptor 2	10	1	0	11
Gamma-aminobutyric acid receptor subunit alpha-5	9	2	0	11
Gamma-aminobutyric acid receptor subunit alpha-3	9	2	0	11
Gamma-aminobutyric acid receptor subunit gamma-1	9	2	0	11
Gamma-aminobutyric acid receptor subunit alpha-2	9	2	0	11
Gamma-aminobutyric acid receptor subunit alpha-4	9	2	0	11
Gamma-aminobutyric acid receptor subunit gamma-3	9	2	0	11
Gamma-aminobutyric acid receptor subunit alpha-6	9	2	0	11
Nuclear receptor ROR-gamma	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	9	2	0	11
Gamma-aminobutyric acid receptor subunit beta-3	9	2	0	11
Gamma-aminobutyric acid receptor subunit beta-2	9	2	0	11
GABA theta subunit	9	2	0	11
Inositol hexakisphosphate kinase 1	8	0	0	8
ATPase family AAA domain-containing protein 5	14	0	0	14
Ataxin-2	14	0	0	14
Gamma-aminobutyric acid receptor subunit epsilon	9	2	0	11
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	8	0	0	8
Genome polyprotein	0	2	1	3
dopamine D1 receptor	3	0	0	3
GLS protein	4	0	0	4
regulator of G-protein signaling 4	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
D(1A) dopamine receptor	3	0	0	3
vitamin D3 receptor isoform VDRA	6	0	0	6
chromobox protein homolog 1	9	0	0	9
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
ATP-dependent translocase ABCB1	0	2	0	2
ATP-dependent translocase ABCB1	0	3	0	7
Beta-1 adrenergic receptor	0	2	0	2
Cytochrome P450 3A4	0	9	0	10
5-hydroxytryptamine receptor 1A	0	4	2	6
Alpha-2A adrenergic receptor	0	11	0	11
D(2) dopamine receptor	0	10	2	16
Androgen receptor	0	7	0	7
Alpha-2B adrenergic receptor	0	9	0	9
Alpha-2C adrenergic receptor	0	9	0	9
D	0	5	0	5
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	6	0	6
Alpha-2B adrenergic receptor	0	4	1	5
ATP-dependent translocase ABCB1	0	2	0	2
D(1A) dopamine receptor	0	8	0	9
Alpha-2C adrenergic receptor	0	4	1	5
Alpha-2A adrenergic receptor	0	4	1	5
Alpha-1D adrenergic receptor	0	10	0	10
D(1B) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	8	1	11
5-hydroxytryptamine receptor 2C	0	6	2	8
5-hydroxytryptamine receptor 1B	0	6	0	6
D(4) dopamine receptor	0	4	0	4
D(3) dopamine receptor	0	10	1	15
Alpha-synuclein	1	3	0	4
5-hydroxytryptamine receptor 2B	0	6	1	7
5-hydroxytryptamine receptor 6	0	5	0	6
D(2) dopamine receptor	0	7	1	8
ATP-dependent phosphofructokinase	7	0	0	7
progesterone receptor	13	0	0	13
Chain A, HADH2 protein	7	0	0	7
Chain B, HADH2 protein	7	0	0	7
Chain A, Cruzipain	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	8	0	0	8
cytochrome P450 2C9 precursor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
Cytochrome P450 1A2	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
Cytochrome P450 2D6	0	3	0	4
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	2	0	3
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	6	0	0	6
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	4	0	4
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Potassium voltage-gated channel subfamily H member 2	0	10	0	11
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
importin subunit beta-1 isoform 1	3	0	0	3
mitogen-activated protein kinase 1	5	0	0	5
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
streptokinase A precursor	0	0	3	3
Solute carrier organic anion transporter family member 1B3	0	3	0	5
Solute carrier organic anion transporter family member 1B1	0	3	0	5
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Neutrophil elastase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Beta-lactamase TEM	0	2	0	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Class D beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase	0	1	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	2
Beta-lactamase class B VIM-2	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
5-hydroxytryptamine receptor 3E	0	1	0	1
Luciferase	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	7	0	0	7
NFKB1 protein, partial	2	0	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
thyroid stimulating hormone receptor	9	0	0	9
estrogen receptor 2 (ER beta)	8	0	0	8
cytochrome P450 2D6	5	0	0	5
Beta-1 adrenergic receptor	0	1	0	1
glucocerebrosidase	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
caspase-3	3	0	0	3
Adenylate cyclase type 1	0	1	0	1
cytochrome P450 2D6 isoform 1	4	0	0	4
cytochrome P450 2C19 precursor	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
DNA polymerase beta	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	6	0	0	6
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
lethal factor (plasmid)	4	0	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Albumin	0	0	2	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	8	1	9
Muscarinic acetylcholine receptor M4	0	6	1	7
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 2C	0	5	0	6
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	6	0	6
Calmodulin-1	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M1	0	6	1	7
Angiotensin-converting enzyme	0	4	0	4
5-hydroxytryptamine receptor 2A	0	5	0	5
Alpha-1B adrenergic receptor	0	6	1	7
Beta-1 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	7	1	8
Endothelin receptor type B	1	1	0	2
D(4) dopamine receptor	0	4	0	6
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Alpha-1D adrenergic receptor	0	4	1	5
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	6	0	6
Adenosine receptor A1	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	1	5
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Sodium-dependent serotonin transporter	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Alpha-1A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
Histamine H1 receptor	0	4	2	8
Alpha-1B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Adenylate cyclase type 8	0	1	0	1
Alpha-1A adrenergic receptor	0	6	1	7
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Spike glycoprotein	6	0	1	7
D(2) dopamine receptor	0	2	0	2
Calmodulin	0	0	1	1
Inositol monophosphatase 1	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Sodium-dependent dopamine transporter	0	3	0	3
5-hydroxytryptamine receptor 2B	0	2	0	2
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
5-hydroxytryptamine receptor 3D	0	1	0	1
Adenylyl cyclase 7	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
D	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Histamine H4 receptor	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Transporter	0	2	0	2
Histamine H3 receptor	0	2	0	2
endonuclease IV	1	0	0	1
PAX8	0	0	0	1
pregnane X receptor	3	0	0	3
USP1 protein, partial	7	0	0	7
PPM1D protein	5	0	0	5
Thrombopoietin	1	0	0	1
Smad3	3	0	0	3
67.9K protein	7	0	0	7
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
nuclear receptor subfamily 0 group B member 1	0	1	0	1
thyroid hormone receptor beta isoform a	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	10	0	0	10
flap endonuclease 1	3	0	0	3
ras-related protein Rab-9A	1	0	0	1
steroidogenic factor 1	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	3	2	6
Tubulin beta chain	0	3	2	6
Tubulin alpha-3C chain	0	3	2	6
Serine/threonine-protein kinase pim-1	0	1	0	1
Tubulin alpha-1B chain	0	3	2	6
Tubulin alpha-4A chain	0	3	2	6
Tubulin beta-4B chain	0	3	2	6
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	3	2	6
Tubulin beta-2A chain	0	3	2	6
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	2	6
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	3	2	6
Tubulin alpha-1A chain	0	3	2	6
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	3	2	6
Tubulin beta-6 chain	0	3	2	6
Tubulin beta-2B chain	0	3	2	6
Tubulin beta-1 chain	0	3	2	6
Serum paraoxonase/arylesterase 1	0	1	0	1
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
alpha synuclein, partial	1	0	0	1
hypothetical protein, conserved	2	0	0	2
luciferase	2	0	0	2
thyrotropin-releasing hormone receptor	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
Caspase-7	1	0	0	1
tumor necrosis factor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
huntingtin isoform 2	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Solute carrier family 22 member 1	0	0	0	1
Epidermal growth factor receptor	0	1	0	1
Integrin beta-3	4	0	0	4
Tyrosine-protein kinase Fyn	0	1	0	1
Integrin alpha-IIb	4	0	0	4
60 kDa chaperonin	0	1	0	1
Adenosine receptor A3	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Substance-K receptor	0	2	0	2
Acetylcholinesterase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Adenosine receptor A2a	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
10 kDa heat shock protein, mitochondrial	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Fatty-acid amide hydrolase 1	1	1	0	2
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Leukotriene B4 receptor 1	1	0	0	1
Thiosulfate sulfurtransferase	0	2	0	2
60 kDa chaperonin	0	2	0	2
Glutamate receptor ionotropic, kainate 5	1	0	0	1
10 kDa chaperonin	0	2	0	2
Leukotriene B4 receptor 2	1	0	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
15-lipoxygenase, partial	3	0	0	3
WRN	1	0	0	1
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
pyruvate kinase	1	0	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
intestinal alkaline phosphatase precursor	0	0	1	1
serine/threonine-protein kinase PLK1	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Vif	0	1	0	1
Tat	0	1	0	1
histone acetyltransferase KAT2A isoform 1	6	0	0	6
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	1	0	1
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Pyruvate kinase PKM	0	1	0	1
Endothelin-1 receptor	1	0	0	1
phosphoglycerate kinase	1	0	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	1	0	1
Myeloperoxidase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA primase	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
transcriptional regulator ERG isoform 3	3	0	0	3
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Purine nucleoside phosphorylase	0	0	1	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	1	0	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Carbonic anhydrase 2	0	2	1	4
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
TAR DNA-binding protein 43	5	0	0	5
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
nonstructural protein 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
glp-1 receptor, partial	3	0	0	3
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	1	0	2
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Caspase-1	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	2
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Albumin	0	0	1	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 12	0	1	0	1
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (83)

Protein Targets (742)

Granulomatous Mastitis

Synonyms(1)

Research Excerpts

Overview

Research

Studies (83)

Drugs Studied (45)

Protein Targets (742)