celesticetin a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

celesticetin A: antibiotic produced by Streptomyces caelestis from soil; active against gram positive & plant pathogens; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	20054860
SCHEMBL ID	3674068
MeSH ID	M0045780

Synonyms (15)

Synonym
4-22-00-00026 (beilstein handbook reference)
unii-8562x82net
8562x82net ,
nsc 9147
d-erythro-d-galacto-octopyranoside, 2-hydroxyethyl 6,8-dideoxy-7-o-methyl-6-(1-methyl-l-2-pyrrolidinecarboxamido)-1-thio-, monosalicylate (ester), alpha-
d-erythro-d-galacto-octopyranoside, 2-hydroxyethyl-6,8-dideoxy-7-o-methyl-6-(1-methyl-l-2-pyrrolidinecarboxamido)-1-thio-, monosalicylate (ester), alpha-
d-erythro-alpha-d-galacto-octopyranoside, 2-((2-hydroxybenzoyl)oxy)ethyl 6,8-dideoxy-7-o-methyl-6-(((1-methyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (s)-
brn 0068470
nsc-9147
celesticetin a
SCHEMBL3674068
d-erythro-.alpha.-d-galacto-octopyranoside, 2-((2-hydroxybenzoyl)oxy)ethyl 6,8-dideoxy-7-o-methyl-6-((((2s)-1-methyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-
celesticetin [mi]
Q27269597
DTXSID501043250

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (14.29)	18.7374
1990's	2 (28.57)	18.2507
2000's	1 (14.29)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
inositol Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.. inositol : Any cyclohexane-1,2,3,4,5,6-hexol.. 1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.. muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.	2.11	1	cyclitol; hexol
chloramphenicol Amphenicol: Chloramphenicol and its derivatives.	1.98	1	C-nitro compound; carboxamide; diol; organochlorine compound	antibacterial drug; antimicrobial agent; Escherichia coli metabolite; geroprotector; Mycoplasma genitalium metabolite; protein synthesis inhibitor
puromycin [no description available]	1.98	1	puromycins	antiinfective agent; antimicrobial agent; antineoplastic agent; EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor; EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor; nucleoside antibiotic; protein synthesis inhibitor
mycothiol mycothiol: a glyco-inositol-cysteine found in MYCOBACTERIUM BOVIS which conjugates exogenous compounds for detoxication; it is a microbe counterpart to eucaryotic GLUTATHIONE; acted on by mycothiol disulfide reductase and mycothiol S-conjugate amidase and MDF dehydrogenase;. mycothiol S-conjugate : Any S-conjugate of mycothiol.. mycothiol : A pseudodisaccharide, 1D-myo-inosityl-alpha-D-glucopyranoside, in which the hydroxy group at the 2-position of the glucose moiety is replaced by an (N-acetyl-L-cysteinyl)amido group.	2.11	1
lincomycin Lincomycin: An antibiotic produced by Streptomyces lincolnensis var. lincolnensis. It has been used in the treatment of staphylococcal, streptococcal, and Bacteroides fragilis infections.. lincomycin : A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis.	3.39	7	carbohydrate-containing antibiotic; L-proline derivative; monocarboxylic acid amide; pyrrolidinecarboxamide; S-glycosyl compound	antimicrobial agent; bacterial metabolite
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.	2.11	1	cysteinium	fundamental metabolite
carbomycin carbomycin: from Streptomyces halstedii	1.98	1
prolyl-proline Pro-Pro : A dipeptide formed from two L-proline residues.	2.08	1	dipeptide	human urinary metabolite; Mycoplasma genitalium metabolite
thiostrepton Thiostrepton: One of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.. thiostrepton : A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitumor agent.	1.98	1
tetracycline Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.. tetracycline : A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.	1.98	1
sparsomycin Sparsomycin: An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems.	1.98	1

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