| Member | Definition | Class |
|---|
| 1,4-dihydroxyanthraquinone | A dihydroxyanthraquinone having the two hydroxy substituents at the 1- and 4-positions; formally derived from anthraquinone by replacement of two hydrogen atoms by hydroxy groups | quinizarin |
| 4-anisyltetrazolium blue | An organic chloride salt having tetrazolium blue(1+) as the counterion. | tetrazolium blue |
| 4-phenylenediamine | A phenylenediamine in which the amino functions are at positions 1 and 4 of the benzene nucleus. | 1,4-phenylenediamine |
| alizarin | A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2. | alizarin |
| bromcresol purple | A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3-bromo-4-hydroxy-5-methylphenyl groups. A hydrophilic dye that is used as a pH indicator and to measure serum albumin concentrations. | bromocresol purple |
| bromphenol blue | 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye. | bromophenol blue |
| bromthymol blue | A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3-bromo-4-hydroxy-5-isopropyl-2-methylphenyl groups. | bromothymol blue |
| c.i. solvent yellow 56 | An azobenzene that is N,N-diethylaniline substituted at position 4 by a phenylazo group. | Solvent yellow 56 |
| clofazimine | 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. | clofazimine |
| cresol red | A member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups. | cresol red |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| disperse blue 124 | A monoazo compound consisting of diazene with a 5-nitrothiazol-2-yl group attached to one nitrogen and a substituted 4-aminophenyl group attached to the other; used as a dye standard for the assay of allergy-releasing dyes in textiles. | Disperse Blue 124 |
| disperse orange 3 | Azobenzene substituted at the phenyl 4-positions by an amino and a nitro group. | 4-(4-nitrophenylazo)aniline |
| indophenol | A quinone imine obtained by formal condensation of one of the keto groups of benzoquinone with the amino group of 4-hydroxyaniline. | indophenol |
| janus green b | | Janus Green B chloride |
| lac dye | A glycoside comprising beta-lactose having a p-(p-dimethylaminophenylazo)phenyl group at the 1-position. | 4-{[4-(dimethylamino)phenyl]diazenyl}phenyl-beta-lactoside |
| neutral red | A hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. | neutral red |
| neutral red base | A member of the class of phenazines carrying methyl, amino and dimethylamino substituents at positions 2, 3 and 7 respectively. The free base of neutral red, which acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. | neutral red base |
| procion brilliant blue hgr | Anthraquinone carrying amino, sulfo and [3-({4-chloro-6-[(3-sulfophenyl)amino]-1,3,5-triazin-2-yl}amino)-4-sulfophenyl]amino substituents at positions 1, 2 and 4 respectively. | Reactive Blue 5 |
| procion orange mx-2r | A 2,4-dichloro-1,3,5-triazine with a multi-substituted napthalen-2-yldiazenyl substituent at the 6-position. | procion orange MX-2R |
| quinophthalone | A quinoline derivative with a 1,3-dioxoindan-2-yl substituent at C-2. | quinoline yellow |
| reactive red 120 dye | A bis(azo) compound that consists of a benzene core having two (4-amino-6-chloro-1,3,5-triazin-2-yl)amino groups attached at positions 1 and 4 and which in turn have 5-hydroxy-6-[(2-sulfophenyl)diazenyl]-2,7-disulfonaphthalen-4-yl groups attached to their 4-amino functions. | Reactive red 120 |
| sulfobromophthalein | An organosulfonic acid that consists of phthalide bearing four bromo substituents at positions 4, 5, 6 and 7 as well as two 4-hydroxy-3-sulfophenyl groups both located at position 1. | bromosulfophthalein |
| sulfobromophthalein sodium | An organic sodium salt that is the disodium salt of bromosulfophthalein. | bromosulfophthalein sodium |
| tetrazolium violet | An organic chloride salt having tetrazolium violet(1+) as the counterion. | tetrazolium violet |
| thiazolyl blue | The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium. | 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide |
| triphenyltetrazolium chloride | An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion. | 2,3,5-triphenyltetrazolium chloride |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 29.4003 | 1 | 4 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 10.8625 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 10.0000 | 2 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 54.7481 | 4 | 11 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 44.0124 | 2 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.5416 | 1 | 5 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 13.8964 | 1 | 3 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 4.9490 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 18.6635 | 10 | 43 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 24.6325 | 3 | 20 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 9.7453 | 2 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 36.2399 | 1 | 8 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 35.4813 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 38.1994 | 2 | 13 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 3.3814 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 46.5900 | 1 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 46.5900 | 1 | 3 |
| Caspase-7 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.3009 | 3 | 11 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 20.6328 | 2 | 4 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 28.3179 | 1 | 4 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 31.6228 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 7.0795 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 26.7594 | 2 | 4 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 46.6874 | 1 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 29.2212 | 2 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 10.8466 | 1 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.9560 | 1 | 3 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 26.7594 | 2 | 4 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 5.7732 | 1 | 2 |
| ClpP | Bacillus subtilis | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 11.5191 | 1 | 3 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 19.5020 | 1 | 4 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 20.4767 | 2 | 10 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 10.0694 | 2 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 34.7674 | 1 | 7 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 27.2454 | 2 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 48.0098 | 2 | 4 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 54.9213 | 2 | 6 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 25.6884 | 1 | 7 |
| endonuclease IV | Escherichia coli | Potency | 12.5893 | 1 | 1 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 14.1254 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 14.1254 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.0183 | 11 | 49 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 28.5441 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 17.7845 | 6 | 39 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 9.2302 | 1 | 3 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 1.9015 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 39.9983 | 4 | 7 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 32.2706 | 2 | 6 |
| G | Vesicular stomatitis virus | Potency | 11.5191 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 20.4767 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 10.4648 | 2 | 7 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 17.8397 | 3 | 19 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 11.4442 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 19.7020 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 40.3879 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 24.8394 | 3 | 9 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 32.8014 | 2 | 6 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 20.0461 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 28.0682 | 2 | 3 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 27.3162 | 2 | 2 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| hepatitis C virus polyprotein | | Potency | 24.9988 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 10.5785 | 1 | 6 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 26.6628 | 2 | 11 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 54.1188 | 2 | 11 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 51.6252 | 1 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 11.5191 | 1 | 3 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 35.4813 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 45.1632 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 4.2907 | 2 | 8 |
| IDH1 | Homo sapiens (human) | Potency | 14.6777 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 59.4390 | 2 | 5 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 11.5191 | 1 | 6 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 13.6758 | 2 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 20.1044 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 20.1044 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 11.5191 | 1 | 3 |
| interleukin 8 | Homo sapiens (human) | Potency | 84.1267 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 16.1599 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 0.0794 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 21.9722 | 4 | 15 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 39.5068 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 10.8736 | 2 | 10 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 19.2256 | 2 | 7 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 20.3510 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 11.4748 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 8.4038 | 4 | 21 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 6.9460 | 1 | 4 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 3.4895 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 22.6874 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 17.4171 | 2 | 12 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 25.5799 | 3 | 26 |
| P53 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 38.8931 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 32.6272 | 1 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 10.0318 | 1 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 23.0736 | 5 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 25.2963 | 5 | 10 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 22.8469 | 2 | 2 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 54.7049 | 1 | 4 |
| PINK1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 16.0825 | 1 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 17.9008 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 10.5785 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 12.5475 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 23.0268 | 3 | 12 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 26.5096 | 1 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 38.7265 | 2 | 5 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 14.1254 | 2 | 2 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 28.1838 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 16.9433 | 2 | 17 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 14.6730 | 3 | 22 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 26.3953 | 4 | 11 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 12.3109 | 1 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 39.9629 | 2 | 5 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 39.9629 | 2 | 5 |
| Smad3 | Homo sapiens (human) | Potency | 22.0649 | 1 | 7 |
| snurportin-1 | Homo sapiens (human) | Potency | 59.4390 | 2 | 5 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 11.6936 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 32.5597 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.7920 | 2 | 24 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 39.8107 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 29.8257 | 2 | 13 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 50.2657 | 3 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 33.7608 | 7 | 18 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 27.7247 | 1 | 1 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 38.4369 | 2 | 4 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 34.2268 | 2 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 16.0825 | 1 | 2 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 16.0825 | 1 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 33.1557 | 2 | 8 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 15.6824 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 37.0876 | 5 | 6 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 29.6165 | 5 | 10 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 36.1919 | 1 | 5 |
| Vpr | Human immunodeficiency virus 1 | Potency | 37.8425 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 47.3936 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 9.6995 | 2 | 2 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 3.0000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 8.3000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 1.7300 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 3.0000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 8.3000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 132.1300 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 81.0100 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 8.1330 | 5 | 5 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 0.3745 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 35.5440 | 5 | 5 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 21.5000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 15.5000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 15.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.8541 | 30 | 30 |
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | Ki | 1.1500 | 1 | 1 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 67.0000 | 2 | 2 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 8.8840 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 0.9000 | 3 | 3 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 7.7510 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 343.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 16.8500 | 4 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 2.4150 | 2 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | Ki | 2.5250 | 2 | 2 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 14.5000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 14.5000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 2.3600 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 300.0000 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 25.0000 | 4 | 4 |
| Cruzipain | Trypanosoma cruzi | IC50 | 23.0000 | 4 | 4 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 7.7500 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 1.0700 | 2 | 2 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 1,160.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 200.0000 | 6 | 6 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | IC50 | 200.0000 | 6 | 6 |
| Gag-Pol polyprotein | HIV-1 M:B_HXB2R | IC50 | 79.0000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 17.9500 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 0.0660 | 1 | 1 |
| Hematopoietic prostaglandin D synthase | Homo sapiens (human) | IC50 | 27.0000 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 21.9167 | 6 | 6 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 50.7900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 97.6700 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 64.9800 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| hypothetical protein SA1422 | Staphylococcus aureus subsp. aureus N315 | IC50 | 42.9000 | 2 | 2 |
| Ileal sodium/bile acid cotransporter | Homo sapiens (human) | Ki | 144.0000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 1.6200 | 1 | 1 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 27.4755 | 2 | 2 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 18.7000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 0.0050 | 1 | 1 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 27.4755 | 2 | 2 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 9.6000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 54.8750 | 4 | 4 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 44.5000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 24.2000 | 1 | 1 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | Mus musculus (house mouse) | IC50 | 2.2000 | 1 | 1 |
| Nuclear hormone receptor family member daf-12 | Caenorhabditis elegans | IC50 | 67.5470 | 1 | 1 |
| oxysterols receptor LXR-beta isoform 1 | Homo sapiens (human) | IC50 | 67.5470 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 9.1670 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 10.2320 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 1.8000 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 63.8350 | 1 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 63.8350 | 1 | 2 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 1,160.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 31.7500 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 31.7500 | 1 | 2 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 100.0000 | 1 | 1 |
| RmtA | Aspergillus nidulans | IC50 | 1,220.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 3.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | Ki | 8.6000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 1.9800 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A3 | Rattus norvegicus (Norway rat) | Ki | 21.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.0500 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.0440 | 1 | 1 |
| Solute carrier organic anion transporter family member 2A1 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sortase A | Streptococcus mutans | IC50 | 10.2000 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 200.0000 | 1 | 1 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 56.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0132 | 1 | 1 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 8.3620 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 19.7000 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| Tyrosinase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |