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1,2-benzoxazoles

Compounds based on a fused 1,2-oxazole and benzene bicyclic ring skeleton, with the O atom positioned adjacent to one of the positions of ring fusion.

ChEBI ID: 51545

Members (6)

MemberDefinitionRole
1,2-benzisoxazoleA benzoxazole in which the benzene ring is fused to a 1,2-oxazole ring across positions 4 and 5.1,2-benzoxazole
hp 873A member of the class of piperidines that is the 4-acetyl-2-methoxyphenyl ether of 3-(piperidin-1-yl)propan-1-ol which is substituted at position 4 of the piperidine ring by a 6-fluoro-1,2-benzoxazol-3-yl group. A member of the group of second generation antipsychotics (also known as an atypical antipsychotics), it is used for the treatment of schizophrenia.iloperidone
paliperidoneA member of the class of pyridopyrimidines that is 9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
paliperidone palmitateA fatty acid ester obtained by the formal condensation of the carboxy group of hexadecanoic acid with the hydroxy group of 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one.3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4-oxo-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-9-yl hexadecanoate
risperidoneA member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.risperidone
zonisamideA 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.zonisamide

Research

Studies (7,990)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199033 (0.41)18.7374
1990's1,012 (12.67)18.2507
2000's3,134 (39.22)29.6817
2010's3,040 (38.05)24.3611
2020's771 (9.65)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,851 (20.47%)5.53%
Reviews1,150 (12.72%)6.00%
Case Studies1,678 (18.56%)4.05%
Observational112 (1.24%)0.25%
Other4,250 (47.01%)84.16%