A type of benzylisoquinoline alkaloid whose structures are built up of two benzylisoquinoline units linked by ether bridges. Various structural patterns resulting from additional bridging between the two units by direct carbon-carbon bridging or by methylenedioxy groups are common.
| Member | Definition | Role |
|---|
| bebeerine | | (+)-Bebeerine |
| berbamine | | Berbamine |
| cepharanthine | A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation. | cepharanthine |
| cycleanine | | Cycleanine |
| dauricine | A bisbenzylisoquinoline alkaloid resulting from the formal oxidative dimerisation of 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenol by attachment of the phenolic oxygen of one molecule to the benzene ring of the second (ortho to the phenolic hydroxy group of the latter). | dauricine |
| fangchinoline | A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity. | fangchinoline |
| guatteguamerine | | Magnoline |
| hernandezine | | Hernandezine |
| obamegine | | Obamegine |
| oxyacanthine | A macrocycle that is oxyacanthan that is substituted by methoxy groups at positions 6, 6', and 7, methyl groups at positions 2 and 2', and a hydroxy group at the 12' position. | oxyacanthine |
| tetrandrine | | (+)-Tetrandrine |
| thalicarpine | | thalicarpine |
| tubocurarine | A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare. | tubocurarine |