Pleural Effusion, Malignant

Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. Malignant pleural effusions often contain actual malignant cells.

Synonym
Pleural Effusion, Malignant

Excerpt	Reference
"Once a malignant pleural effusion is diagnosed, appropriate therapy may provide symptomatic relief and improved quality of life."	( Moffett, MJ; Ruckdeschel, JC, 1992)
"Malignant pleural effusions are a common and significant problem in patients with advanced malignancies."	( Kreuser, ED, 1992)
"Malignant pleural effusions are often symptomatic and tend to recur after simple aspiration."	( Hulks, G; McAlpine, LG; Thomson, NC, 1990)
"Chronic malignant pleural effusions are usually treated with an intrapleurally administered irritant that creates an inflammatory reaction."	( Agrenius, V; Blombäck, M; Chmielewska, J; Widström, O, 1991)
"Malignant pleural effusions are a common and significant problem in patients with advanced malignancies."	( Figlin, R; Godwin, D; Piantadosi, S; Rusch, VW, 1991)
"Malignant pleural effusions are a common and significant problem in patients with advanced malignancies."	( Figlin, R; Mendoza, E; Piantadosi, S; Rusch, V, 1994)
"Malignant pleural effusion is a frequent complication of metastatic breast cancer leading to a significant degree of morbidity."	( Coombes, RC; Evans, TR; Ford, HT; Gazet, JC; Pepper, JR; Stein, RC, 1993)
"Malignant pleural effusions are commonly managed with tube thoracostomy drainage followed by chemical pleurodesis."	( Aparicio, J; Gil-Suay, V; Martínez-Moragón, E; Rogado, MC; Sanchis, F; Sanchis, J, 1997)
"Malignant pleural effusions are classically exudative, though occasionally they can be transudative."	( Ashchi, M; Eng, P; Golish, J; O'Donovan, P, 1998)
"Malignant pleural effusion is a frequent complication of patients with advanced malignant tumors."	( Cheng, D; Tang, X, 1997)
"The management of malignant pleural effusions are a common, and sometimes difficult, therapeutic problem."	( Antunes, G; Weatherhead, M, 2004)
"Malignant pleural effusion is a common complication of primary and metastatic pleural malignancies."	( Akay, H; Cangir, AK; Enön, S; Kadilar, C; Kavukçu, S; Kilic, D; Kutlay, H, 2005)
"Malignant pleural effusion is typical of complications in advanced lung cancer patients, most of whom complain of dyspnea."	( Akusawa, H; Horie, T; Kisohara, A; Sato, M; Shimizu, T; Sugane, T; Takahashi, N; Terakado, M; Tsujino, I, 2005)
"Malignant pleural effusion is a common and devastating complication of metastatic breast cancer."	( Itoh, K; Matsubara, N; Mukai, H; Nagai, S, 2012)
"Malignant pleural effusion is a common complication in certain malignancies."	( Alavi, AA; Eshraghi, M; Hajian, H; Meysami, AP; Morteza, A; Rahim, MB, 2011)
"The diagnosis of malignant pleural effusions is an important issue in the management of malignancy patients."	( Chang, TC; Huang, WC; Jan, IS; Kang, CC; Lin, IT; Lin, MY; Lou, PJ; Shih, JY; Tsai, TH; Tsai, YL; Wang, CL; Wang, HC; Wu, HD, 2014)
"Malignant pleural effusion is a common complication of non-small cell lung cancer (NSCLC); however, treatment options remain limited."	( Gao, M; Li, C; Li, T; Li, Y; Qi, Q; Wang, A; Wang, B; Xu, L; Zhang, Y, 2018)
"malignant pleural effusion is a devastating condition as it heralds the end-of-life processes of a primary malignancy."	( Okugbo, S; Omoregbee, BI, 2021)
"Malignant pleural effusion is common in mesothelioma."	( Duckworth, A; Foo, CT; Herre, J; Paterson, A, 2021)

Excerpt	Reference
"Several techniques for palliative treatment of malignant pleural effusions (MPE) are recommended; in particular, sclerosing agents have been instilled into the pleural cavity."	( Furrer, M; Inderbitzi, R, 1992)
"For the treatment of malignant pleural effusions, we prepared doxorubicin hydrochloride (Adriamycin)-containing poly(L-lactic acid) microspheres (ADR-MS)."	( Hitomi, S; Ikada, Y; Ike, O; Shimizu, Y; Wada, R, 1991)
"Chemical pleurodesis is an effective treatment of malignant pleural effusions, but indications must be individualised to optimise its results."	( Aparicio, J; Cruz Rogado, M; Martínez-Moragón, E; Menéndez, R; Sanchis, F; Sanchis, J, 1998)
"To evaluate the efficacy of treating malignant pleural effusion with cisplatine and vindesine by injection through thoracic tube intubation."	( Li, D; Wu, Z; Zhang, Z, 2001)
"Hypotonic cisplatin treatment for malignant pleural effusion of NSCLC is therefore considered to be feasible and effective."	( Araki, J; Ichinose, Y; Inoue, Y; Ito, K; Semba, H; Seto, T; Ushijima, S; Yamamoto, H, 2006)
"When conventional treatments of malignant pleural effusion, such as repeated thoracentesis, closed thoracotomy and pleurodesis by instilled sclerosing agents, are ineffective, there are few alternative therapies available."	( Cho, BC; Choi, HJ; Choi, ST; Kim, YT; Moon, YW, 2007)
"IC-CDDP was effective in treating malignant pleural effusions and may be a palliative option for refractory disease."	( George, B; Katzenstein, HM; Olson, TA; Petricca, S; Powell, C; Rapkin, L; Ricketts, R; Wasilewski-Masker, K; Woods, WG, 2010)
"The approach to palliative treatment of malignant pleural effusion (MPE) should be individualized because these patients generally have poor survival."	( Baretta, R; Cardoso, GP; Cunha, ET; da Silva, CT; Zamboni, MM, 2015)
"Elemene is widely used to treat malignant pleural effusion in China."	( Li, J; Liang, J; Wang, QT; Wang, YF; Xiong, H; Zhang, ZL; Zhou, DS, 2018)
"(ZJ), is usually used for treating malignant pleural effusions (MPE), but the toxicity of EK and EP limits its clinical safe application."	( Bao, BH; Guo, SJ; Li, ZL; Tang, YP; Xu, JD; Xu, QQ; Yao, WF; Zhang, L; Zhang, Q; Zhang, Y, 2021)
"In the clinical treatment of malignant pleural effusion and ascites, bevacizumab combined with cisplatin intracavitary perfusion can improve the clinical treatment effect, reduce the depression and anxiety of patients, optimize patient quality of life, and improve the safety of treatment."	( Hu, D; Li, H; Xie, L; Zhou, Z, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	14 (1.77)	23.3326
1990's	230 (29.11)	12.5806
2000's	237 (30.00)	18.1394
2010's	253 (32.03)	28.8240
2020's	56 (7.09)	9.53

Drug	Relationship Strength	Studies	Trials
aminolevulinic acid	medium	1	1
acetic acid	low	1	0
adenine	low	3	0
ammonium hydroxide	low	1	0
quinacrine	medium	13	3
carnitine	low	1	0
salicylic acid	low	1	0
creatine	low	1	0
lactic acid	medium	3	1
formaldehyde	low	4	0
dalteparin	low	1	0
iodine	medium	4	1
kynurenine	low	1	0
methanol	low	1	0
melatonin	low	1	0
niacinamide	low	1	0
nitrates	low	2	0
nitrites	low	2	0
thiosulfates	low	2	0
uracil	low	2	0
diatrizoic acid	low	1	0
anastrozole	low	2	0
azathioprine	low	1	0
busulfan	low	1	0
verapamil	low	1	0
celecoxib	low	1	0
chlorothiazide	low	1	0
ciprofloxacin	low	1	0
dapi	low	1	0
pentetic acid	low	1	0
flucytosine	low	1	0
fluorouracil	medium	10	2
flutamide	low	1	0
gentamicin	low	1	0
hydroxyurea	low	1	0
lidocaine	low	2	0
ifosfamide	medium	8	1
staurosporine aglycone	low	1	0
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1	0
mechlorethamine	medium	7	1
mitoxantrone	medium	16	5
oxonic acid	low	3	0
pamidronate	low	1	0
phenacetin	low	1	0
propofol	low	2	0
sobuzoxane	low	1	0
sodium iodide	low	1	0
vorinostat	low	1	0
tegafur	low	4	0
thalidomide	low	7	0
thiotepa	low	1	0
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2h-tetrazolium hydroxide	low	1	0
mitomycin	medium	4	2
prednisolone	low	8	0
thymidine	low	1	0
floxuridine	low	2	0
thyroxine	low	1	0
aldosterone	low	1	0
prednisone	low	13	0
methylprednisolone acetate	medium	2	1
cantharidin	low	1	0
edetic acid	low	1	0
tyrosine	low	1	0
methylene blue	low	3	0
phenylalanine	medium	3	1
colchicine	low	1	0
cytarabine	medium	7	3
medroxyprogesterone acetate	low	2	0
tryptophan	low	1	0
arginine	low	1	0
methylprednisolone	medium	4	2
n-vinyl-2-pyrrolidinone	medium	3	1
thymol	low	2	0
3,3'-diaminobenzidine	low	1	0
xanthenes	low	2	0
nonoxynol	low	1	0
2-ethylhexanol	low	1	0
maleic anhydride	low	1	0
pyrroles	low	2	0
thiophenes	medium	3	1
1-hexanol	low	1	0
quinazolines	medium	24	3
indazoles	low	2	0
thiazoles	medium	3	1
pyrazines	low	5	0
evans blue	low	1	0
azacitidine	low	1	0
elemene	medium	6	1
hematoxylin	low	3	0
medroxyprogesterone	low	1	0
eosine yellowish-(ys)	low	3	0
erythromycin	medium	3	1
deoxycytidine	medium	13	3
carmine	low	1	0
sodium hydroxide	low	1	0
thorium dioxide	low	1	0
arsenic trioxide	low	1	0
vancomycin	low	1	0
pseudouridine	medium	1	1
doxifluridine	low	2	0
mannose	low	1	0
megestrol	low	1	0
vidarabine	low	2	0
iodinated glycerol	low	2	0
platinum	low	11	0
technetium	low	1	0
chromium	low	3	0
gold	low	1	0
yttrium	low	1	0
phosphoric acid, trisodium salt	low	1	0
camptothecin	low	7	0
potassium nitrate	low	1	0
sodium sulfate	medium	1	1
silver nitrate	medium	10	5
sodium thiosulfate	low	2	0
4-chloro-7-nitrobenzofurazan	low	1	0
levamisole	low	1	0
tetradecanoylphorbol acetate	low	2	0
iodine	low	1	0
gallium citrate	low	1	0
s-adenosylmethionine	low	1	0
paclitaxel	medium	31	7
etoposide	medium	11	1
lentinan	low	5	0
ng-nitroarginine methyl ester	low	1	0
vindesine	medium	3	1
epirubicin	low	5	0
fadrozole	low	1	0
aromasil	low	1	0
gemcitabine	medium	13	3
temoporfin	medium	1	1
irinotecan	low	7	0
adenosine	low	1	0
chromic phosphate	low	5	0
deoxyuridine triphosphate	low	1	0
thomsen-friedenreich antigen	low	1	0
distearoyl phosphatidylglycerol	low	1	0
tomatidine	low	1	0
triazoles	low	3	0
fluorodeoxyglucose f18	medium	23	2
zoledronic acid	medium	4	1
honokiol	low	1	0
tetrandrine	low	1	0
clarithromycin	low	1	0
fibrinogen	low	3	0
homocysteine	low	3	0
fulvestrant	low	1	0
uftoral	low	2	0
yttrium radioisotopes	low	3	0
vitamin b 6	low	1	0
tesmilifene	low	1	0
deoxyglucose	low	1	0
bis-neodecanoato-1,2-diaminocyclohexaneplatinum(ii)	medium	1	1
disodium cantharidin	low	1	0
imatinib mesylate	medium	5	1
gefitinib	medium	17	1
t-kinin	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
methotrexate	medium	6	1
pomalidomide	low	2	0
docetaxel anhydrous	medium	18	4
vatalanib	low	1	0
resiquimod	low	1	0
angiotensin ii	low	1	0
atropine	low	1	0
erlotinib hydrochloride	medium	11	2
sorafenib	low	1	0
lenalidomide	low	1	0
3-nitrotyrosine	low	1	0
bortezomib	low	7	0
povidone-iodine	medium	20	8
carboplatin	medium	37	7
n-acetylneuraminic acid	low	5	0
fibrin	low	4	0
bradykinin	low	1	0
n-acetyllactosamine	low	1	0
meropenem	low	1	0
cyclopamine	low	1	0
lignans	low	1	0
tretinoin	low	2	0
keratan sulfate	low	1	0
cefoxitin	low	2	0
diethylstilbestrol	low	1	0
afimoxifene	low	1	0
texas red	low	1	0
melphalan	low	5	0
sodium bicarbonate	low	1	0
potassium nitrite	low	1	0
bromochloroacetic acid	medium	34	1
isomethyleugenol	low	2	0
picibanil	medium	35	5
leuprolide	low	1	0
fludarabine	low	2	0
sesquiterpenes	medium	6	1
curcumin	medium	2	1
sulindac	low	1	0
tamoxifen	low	7	0
krn 7000	low	2	0
toremifene	low	1	0
dasatinib	medium	6	2
zd 6474	medium	3	1
2-fluoro-2-deoxyglucose-6-phosphate	low	1	0
mtt formazan	low	1	0
cathepsin g	low	1	0
dinoprostone	low	1	0
dinoprost	low	1	0
vitamin k semiquinone radical	low	2	0
leukotriene b4	low	1	0
8-epi-prostaglandin f2alpha	low	1	0
zinostatin	low	1	0
sirolimus	low	3	0
alvocidib	low	1	0
morphine	low	1	0
goserelin	low	1	0
bosutinib	low	1	0
semaxinib	low	1	0
orantinib	low	1	0
arsenic	low	1	0
gallium	low	1	0
batimastat	medium	3	1
phosphorus	low	2	0
strontium radioisotopes	low	1	0
axitinib	low	1	0
gadolinium dtpa	low	1	0
romurtide	medium	1	1
belinostat	medium	1	1
cysmethynil	low	1	0
taxane	low	2	0
formazans	low	1	0
lenvatinib	low	1	0
mart-1 antigen	low	1	0
tae226	low	1	0
pazopanib	low	1	0
yttrium silicate	low	1	0
artenimol	low	1	0
pirarubicin	low	5	0
crizotinib	low	6	0
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc	low	2	0
2-(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose	low	1	0
acid phosphatase	low	1	0
bleomycetin	medium	2	1
cytochrome c-t	low	2	0
atrial natriuretic factor	low	1	0
calpain	low	1	0
technetium tc 99m sestamibi	medium	4	1
gdc 0449	low	1	0
pci 32765	low	3	0
fibrinopeptide a	low	1	0
piperidines	medium	8	1
thymosin	low	1	0
interleukin-8	low	20	0
apatinib	low	1	0
alectinib	low	1	0
natriuretic peptide, brain	low	7	0
heparitin sulfate	low	2	0
ascorbic acid	low	1	0
tetracycline	medium	41	11
oxytetracycline, anhydrous	medium	3	1
minocycline	low	3	0
warfarin	low	2	0
s 1 (combination)	low	3	0
calca protein, human	low	4	0
transforming growth factor beta	low	16	0
ceritinib	low	1	0
rome	medium	1	1
osimertinib	medium	6	2
agar	low	2	0
cyclin d1	low	3	0
fluconazole	low	1	0
lewis x antigen	low	3	0
hyaluronoglucosaminidase	low	3	0
transforming growth factor alpha	low	1	0
lactoferrin	low	1	0
tomatine	low	1	0
technetium tc 99m medronate	low	8	0
apyrase	low	1	0
thromboplastin	low	3	0
muramidase	low	2	0
nedaplatin	medium	2	1
lewis y antigen	low	1	0
exudates	low	1	0
angiogenin	low	2	0
levoleucovorin	low	2	0
deoxyguanosine	low	1	0
guanine	medium	12	1
neopterin	low	4	0
dacarbazine	low	2	0
pemetrexed	medium	18	3
8-hydroxy-2'-deoxyguanosine	low	1	0
lipoteichoic acid	medium	2	1
phosphorus radioisotopes	low	2	0

Protein Targets (2,123)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
thyroid stimulating hormone receptor	19	0	0	19
estrogen nuclear receptor alpha	83	0	0	83
vitamin D (1,25- dihydroxyvitamin D3) receptor	32	0	0	32
thyroid hormone receptor beta isoform a	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 1	58	0	0	58
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
Chain A, 2-oxoglutarate Oxygenase	21	0	0	21
Chain A, Cruzipain	10	0	0	10
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	35	0	0	35
15-lipoxygenase, partial	12	0	0	12
ATAD5 protein, partial	18	0	0	18
NFKB1 protein, partial	8	0	0	8
TDP1 protein	76	0	0	76
Thrombopoietin	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	30	0	0	30
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
regulator of G-protein signaling 4	17	0	0	17
EWS/FLI fusion protein	54	0	0	55
67.9K protein	32	0	0	32
Parkin	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	50	0	0	50
cytochrome P450 2D6 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	14	0	0	14
cytochrome P450 2C19 precursor	9	0	0	9
cytochrome P450 2C9 precursor	7	0	0	7
chromobox protein homolog 1	31	0	0	31
flap endonuclease 1	20	0	0	20
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
survival motor neuron protein isoform d	20	0	0	20
cytochrome P450 3A4 isoform 1	23	0	0	23
M-phase phosphoprotein 8	15	0	0	15
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	4	10	15
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	4	17	21
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	10	11
Gamma-aminobutyric acid receptor subunit pi	23	2	1	26
Polyunsaturated fatty acid lipoxygenase ALOX15B	11	0	0	11
Bromodomain-containing protein 4	0	4	0	4
5-hydroxytryptamine receptor 4	0	14	0	14
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Integrin beta-3	11	1	0	12
Cytochrome P450 1A2	0	8	1	10
Integrin alpha-IIb	11	0	0	11
Neuronal acetylcholine receptor subunit alpha-4	1	3	0	4
Serine/threonine-protein kinase pim-1	0	2	17	19
Neuronal acetylcholine receptor subunit beta-2	1	3	0	4
Gamma-aminobutyric acid receptor subunit beta-1	23	2	1	26
Gamma-aminobutyric acid receptor subunit delta	23	2	1	26
Gamma-aminobutyric acid receptor subunit gamma-2	23	2	1	26
Casein kinase II subunit alpha'	0	2	17	19
Gamma-aminobutyric acid receptor subunit alpha-5	23	2	1	26
Gamma-aminobutyric acid receptor subunit alpha-3	23	2	1	26
Gamma-aminobutyric acid receptor subunit gamma-1	23	2	1	26
Gamma-aminobutyric acid receptor subunit alpha-2	23	2	1	26
Proteinase-activated receptor 1	0	1	1	3
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	2	0	3
5-hydroxytryptamine receptor 2A	0	11	0	11
5-hydroxytryptamine receptor 2C	0	15	0	15
Gamma-aminobutyric acid receptor subunit alpha-4	23	2	1	26
Gamma-aminobutyric acid receptor subunit gamma-3	23	2	1	26
Gamma-aminobutyric acid receptor subunit alpha-6	23	2	1	26
Sodium-dependent serotonin transporter	0	6	1	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	15	0	15
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	6	10	17
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	4	10	16
Serine/threonine-protein kinase mTOR	0	5	11	16
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	16	1	0	18
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	4	10	15
Glycogen synthase kinase-3 beta	0	6	17	23
D(1A) dopamine receptor	6	0	0	6
Serine/threonine-protein kinase PLK1	0	5	15	20
Gamma-aminobutyric acid receptor subunit alpha-1	23	3	1	27
Gamma-aminobutyric acid receptor subunit beta-3	23	2	1	26
Gamma-aminobutyric acid receptor subunit beta-2	23	2	1	26
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	10	12
DNA-dependent protein kinase catalytic subunit	0	5	0	5
Mu-type opioid receptor	0	6	0	6
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	6	7
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	10	11
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	23	2	1	26
Gamma-aminobutyric acid receptor subunit epsilon	23	2	1	26
Serine/threonine-protein kinase PLK3	0	5	10	15
Serine/threonine-protein kinase PLK2	0	4	10	14
ATP-dependent phosphofructokinase	22	0	0	22
estrogen receptor 2 (ER beta)	33	0	0	33
retinoid X nuclear receptor alpha	45	0	0	45
peroxisome proliferator activated receptor gamma	39	0	0	39
aryl hydrocarbon receptor	36	0	0	36
DNA polymerase iota isoform a (long)	28	0	0	28
geminin	68	0	0	68
Cellular tumor antigen p53	57	0	0	57
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
Chain A, JmjC domain-containing histone demethylation protein 3A	13	0	0	13
phosphopantetheinyl transferase	23	0	0	23
bromodomain adjacent to zinc finger domain 2B	12	0	0	12
pyruvate kinase PKM isoform a	3	0	0	3
Glycoprotein hormones alpha chain	3	0	0	3
Guanine nucleotide-binding protein G	6	0	0	6
Tubulin--tyrosine ligase	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	21	0	0	21
Luciferase	22	0	0	22
RAR-related orphan receptor gamma	53	0	0	53
GLI family zinc finger 3	60	0	0	60
AR protein	73	0	0	73
nuclear receptor subfamily 1, group I, member 3	52	0	0	52
progesterone receptor	40	0	0	40
glucocorticoid receptor [Homo sapiens]	65	0	0	65
retinoic acid nuclear receptor alpha variant 1	51	0	0	51
estrogen-related nuclear receptor alpha	69	0	0	69
farnesoid X nuclear receptor	40	0	0	40
pregnane X nuclear receptor	56	0	0	56
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	48	0	0	48
thyroid stimulating hormone receptor	28	0	0	28
activating transcription factor 6	25	0	0	25
v-jun sarcoma virus 17 oncogene homolog (avian)	25	0	0	25
Histone H2A.x	29	0	0	29
histone deacetylase 9 isoform 3	9	0	0	9
heat shock protein beta-1	19	0	0	19
Voltage-dependent calcium channel gamma-2 subunit	36	0	0	36
Glutamate receptor 2	37	0	0	37
NPYLR7B	0	0	4	4
Replicase polyprotein 1ab	0	1	4	5
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	10	18	28
Tyrosine-protein kinase Fyn	0	10	18	28
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	33	0	0	33
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	50	0	0	50
nuclear factor erythroid 2-related factor 2 isoform 2	27	0	0	27
importin subunit beta-1 isoform 1	10	0	0	10
snurportin-1	10	0	0	10
tumor susceptibility gene 101 protein	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	7	0	0	7
lamin isoform A-delta10	50	0	0	50
Bile salt export pump	0	59	0	59
Cyclin-dependent kinase 1	0	8	17	26
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	9	1	0	10
Protein mono-ADP-ribosyltransferase PARP15	0	3	0	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	10	12
ATPase family AAA domain-containing protein 5	31	0	0	31
Ataxin-2	35	0	0	35
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
arylsulfatase A	15	0	0	15
IDH1	25	0	0	25
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
mitogen-activated protein kinase 1	14	0	0	14
nuclear receptor ROR-gamma isoform 1	23	0	0	23
peripheral myelin protein 22	31	0	0	31
high affinity choline transporter 1 isoform a	0	3	0	3
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	11	11
Sodium/nucleoside cotransporter 2	0	3	0	3
Rap guanine nucleotide exchange factor 3	9	0	0	9
Purine nucleoside phosphorylase	0	3	0	3
Epidermal growth factor receptor	0	28	21	50
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	15	12	27
Insulin receptor	0	8	17	26
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	2	4
Platelet-derived growth factor receptor beta	0	12	17	30
Adenosine receptor A3	0	11	2	14
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	10	17	30
Inosine-5'-monophosphate dehydrogenase 2	0	1	16	17
Endoplasmin	0	1	1	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	3	10	14
Fibroblast growth factor receptor 4	0	2	10	13
Fibroblast growth factor receptor 3	0	3	10	14
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	2	1	5
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	6	2	9
Adenosine receptor A2b	0	0	1	2
Adenosine receptor A2b	0	1	1	2
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	7	2	10
Adenosine receptor A2a	0	1	1	4
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	2	0	3
Adenosine receptor A1	0	0	1	1
Adenosine kinase	0	0	17	18
Adenosine deaminase	0	0	0	3
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	3
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	3	0	3
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	3
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	2	10	13
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Beta-lactamase	23	0	0	23
Chain A, Ferritin light chain	16	0	0	16
acetylcholinesterase	26	0	0	26
glp-1 receptor, partial	15	0	0	15
pregnane X receptor	11	0	0	11
hypoxia-inducible factor 1 alpha subunit	22	0	0	22
SMAD family member 2	16	0	0	16
SMAD family member 3	16	0	0	16
Microtubule-associated protein tau	23	0	0	23
Smad3	20	0	0	20
apical membrane antigen 1, AMA1	9	0	0	9
caspase 7, apoptosis-related cysteine protease	17	0	0	17
nonstructural protein 1	12	0	0	12
glucocerebrosidase	10	0	0	10
peroxisome proliferator-activated receptor delta	33	0	0	33
caspase-3	17	0	0	17
thyrotropin-releasing hormone receptor	6	0	0	6
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	18	0	0	18
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
thyroid hormone receptor beta isoform 2	60	0	0	60
ubiquitin-conjugating enzyme E2 N	0	2	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	16	0	0	16
plasminogen precursor	16	0	0	16
urokinase plasminogen activator surface receptor precursor	16	0	0	16
neuropeptide S receptor isoform A	8	0	0	8
Phospholipase D2	0	1	0	1
Estrogen receptor	0	10	5	19
Aromatase	0	10	0	10
Estrogen-related receptor gamma	0	2	2	4
Phospholipase D1	0	2	0	2
Estrogen receptor beta	0	10	3	13
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	4	3	7
Androgen receptor	0	14	0	14
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	17	17
Cell division cycle 7-related protein kinase	0	0	11	11
ATP-dependent RNA helicase DDX3X	0	0	17	17
Pyridoxal kinase	0	0	17	17
Citron Rho-interacting kinase	0	0	17	17
Serine/threonine-protein kinase Chk1	0	0	18	18
Aurora kinase A	0	3	17	20
Cyclin-G-associated kinase	0	2	17	19
Ephrin type-B receptor 6	0	0	17	17
Peroxisomal acyl-coenzyme A oxidase 3	0	0	17	17
Receptor-interacting serine/threonine-protein kinase 2	0	3	17	20
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	17	17
Dynamin-like 120 kDa protein, mitochondrial	0	0	17	17
Eukaryotic translation initiation factor 5B	0	0	12	12
Rho-associated protein kinase 2	0	1	17	18
Serine/threonine-protein kinase ULK1	0	0	17	17
Serine/threonine-protein kinase/endoribonuclease IRE1	0	2	17	19
Ribosomal protein S6 kinase alpha-5	0	0	17	17
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	17	17
Ribosomal protein S6 kinase alpha-4	0	0	17	17
Serine/threonine-protein kinase 16	0	0	17	17
Cyclin-dependent kinase-like 5	0	0	15	15
Serine/threonine-protein kinase 10	0	1	17	18
Serine/threonine-protein kinase D3	0	3	18	21
Structural maintenance of chromosomes protein 2	0	0	17	17
Mitogen-activated protein kinase kinase kinase 6	0	0	17	17
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	17	17
Serine/threonine-protein kinase LATS1	0	0	17	17
Serine/threonine-protein kinase PAK 4	0	0	17	17
Tyrosine-protein kinase ABL1	0	18	20	41
High affinity nerve growth factor receptor	0	3	16	19
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	14	14
ADP/ATP translocase 2	0	0	17	17
Protein kinase C beta type	0	4	18	22
Glycogen phosphorylase, liver form	0	0	17	17
Tyrosine-protein kinase Fes/Fps	0	1	17	18
Adenine phosphoribosyltransferase	0	0	13	13
Tyrosine-protein kinase Yes	0	3	17	20
Tyrosine-protein kinase Lyn	0	4	17	21
Proto-oncogene tyrosine-protein kinase receptor Ret	0	12	17	29
Insulin-like growth factor 1 receptor	0	9	17	26
Signal recognition particle receptor subunit alpha	0	0	16	16
Cytochrome c1, heme protein, mitochondrial	0	0	17	17
Hepatocyte growth factor receptor	0	7	16	23
Tyrosine-protein kinase HCK	0	6	17	23
Proto-oncogene tyrosine-protein kinase ROS	0	6	10	16
Tyrosine-protein kinase Fgr	0	4	13	17
Serine/threonine-protein kinase A-Raf	0	1	17	18
Mast/stem cell growth factor receptor Kit	0	11	11	22
Glycogen phosphorylase, brain form	0	0	17	17
Breakpoint cluster region protein	0	6	19	28
DNA topoisomerase 2-alpha	0	4	17	30
Cyclin-dependent kinase 4	0	5	17	23
ADP/ATP translocase 3	0	0	17	17
Proto-oncogene tyrosine-protein kinase Src	0	14	17	31
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	17	17
Serine/threonine-protein kinase B-raf	0	4	18	22
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	17	17
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	17	19
Tyrosine-protein kinase Fer	0	1	17	18
Protein kinase C alpha type	0	5	18	23
cAMP-dependent protein kinase catalytic subunit alpha	0	3	17	20
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	17	17
Ras-related protein Rab-6A	0	0	15	15
Ephrin type-A receptor 1	0	0	17	17
Multifunctional protein ADE2	0	0	17	17
cAMP-dependent protein kinase catalytic subunit gamma	0	3	15	18
cAMP-dependent protein kinase catalytic subunit beta	0	3	17	20
Ferrochelatase, mitochondrial	0	0	17	17
Ribosomal protein S6 kinase beta-1	0	1	16	17
Tyrosine-protein kinase JAK1	0	4	17	21
Cyclin-dependent kinase 2	0	8	18	28
Beta-adrenergic receptor kinase 1	0	0	17	17
Probable ATP-dependent RNA helicase DDX6	0	0	17	17
Mitogen-activated protein kinase 3	0	2	17	19
MAP/microtubule affinity-regulating kinase 3	0	0	17	17
Deoxycytidine kinase	0	0	17	21
Mitogen-activated protein kinase 1	0	2	17	19
Ephrin type-A receptor 2	0	4	17	21
Ephrin type-B receptor 2	0	3	17	20
Non-receptor tyrosine-protein kinase TYK2	0	1	17	18
UMP-CMP kinase	0	0	10	10
Phosphatidylethanolamine-binding protein 1	0	0	14	14
Wee1-like protein kinase	0	0	17	17
Heme oxygenase 2	0	0	17	17
S-adenosylmethionine synthase isoform type-2	0	0	15	15
DnaJ homolog subfamily A member 1	0	0	17	17
RAC-alpha serine/threonine-protein kinase	0	2	17	19
RAC-beta serine/threonine-protein kinase	0	2	17	19
Dual specificity protein kinase TTK	0	0	15	15
DNA replication licensing factor MCM4	0	0	17	17
Myosin-10	0	0	13	13
Vascular endothelial growth factor receptor 2	0	18	12	32
Dual specificity mitogen-activated protein kinase kinase 2	0	2	17	19
Receptor-type tyrosine-protein kinase FLT3	0	9	17	26
Bone morphogenetic protein receptor type-1A	0	0	17	17
Activin receptor type-1B	0	0	17	17
TGF-beta receptor type-1	0	0	17	17
TGF-beta receptor type-2	0	0	16	16
Electron transfer flavoprotein subunit beta	0	0	13	13
Tyrosine-protein kinase CSK	0	3	17	20
Glycine--tRNA ligase	0	0	17	17
Protein kinase C iota type	0	3	18	21
Exosome RNA helicase MTR4	0	0	17	17
Tyrosine-protein kinase Tec	0	3	17	20
Tyrosine-protein kinase ABL2	0	1	17	18
Tyrosine-protein kinase FRK	0	2	17	19
G protein-coupled receptor kinase 6	0	0	14	14
Tyrosine-protein kinase SYK	0	4	17	21
26S proteasome regulatory subunit 6B	0	1	17	18
Mitogen-activated protein kinase 8	0	0	17	17
Mitogen-activated protein kinase 9	0	0	17	17
Dual specificity mitogen-activated protein kinase kinase 3	0	0	17	17
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	15	15
Casein kinase I isoform alpha	0	3	16	19
Casein kinase I isoform delta	0	0	17	17
MAP kinase-activated protein kinase 2	0	1	17	18
Elongation factor Tu, mitochondrial	0	0	17	17
Choline-phosphate cytidylyltransferase A	0	0	11	11
Cysteine--tRNA ligase, cytoplasmic	0	0	15	15
Casein kinase I isoform epsilon	0	0	17	17
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	17	17
Dual specificity protein kinase CLK1	0	0	17	17
Dual specificity protein kinase CLK2	0	0	17	17
Dual specificity protein kinase CLK3	0	0	15	15
Glycogen synthase kinase-3 alpha	0	2	17	19
Cyclin-dependent kinase 7	0	2	17	19
Cyclin-dependent kinase 9	0	2	17	19
Ras-related protein Rab-27A	0	0	17	17
Interleukin-1 receptor-associated kinase 1	0	0	17	17
Ribosomal protein S6 kinase alpha-3	0	1	17	18
Serine/threonine-protein kinase Nek2	0	0	17	17
Serine/threonine-protein kinase Nek3	0	0	17	17
Dual specificity mitogen-activated protein kinase kinase 6	0	0	17	17
LIM domain kinase 1	0	1	17	18
LIM domain kinase 2	0	1	17	18
Mitogen-activated protein kinase 10	0	0	17	17
Tyrosine--tRNA ligase, cytoplasmic	0	0	17	17
5'-AMP-activated protein kinase subunit gamma-1	0	0	17	18
Ephrin type-B receptor 3	0	0	17	17
Ephrin type-A receptor 5	0	0	17	17
Ephrin type-B receptor 4	0	5	17	22
Ephrin type-A receptor 4	0	0	17	17
Adenylate kinase 2, mitochondrial	0	0	17	17
Spike glycoprotein	33	0	4	37
Ras-related protein Rab-10	0	0	16	16
Actin-related protein 3	0	0	17	17
Actin-related protein 2	0	0	17	17
GTP-binding nuclear protein Ran	0	0	17	17
Casein kinase I isoform gamma-2	0	0	16	16
Cyclin-dependent kinase 3	0	0	15	15
Cyclin-dependent kinase 6	0	2	17	19
Cyclin-dependent-like kinase 5	0	1	17	18
Cyclin-dependent kinase 16	0	0	17	17
Cyclin-dependent kinase 17	0	0	17	17
ATP-dependent 6-phosphofructokinase, platelet type	0	0	16	16
Dual specificity mitogen-activated protein kinase kinase 1	0	3	17	20
DNA topoisomerase 2-beta	0	1	18	27
Protein kinase C theta type	0	3	18	21
Activin receptor type-1	0	0	17	17
Macrophage-stimulating protein receptor	0	3	17	20
Focal adhesion kinase 1	0	3	17	20
Protein kinase C zeta type	0	4	13	17
Protein kinase C delta type	0	5	18	23
Tyrosine-protein kinase BTK	0	8	18	26
Cyclin-dependent kinase 18	0	0	12	12
Activated CDC42 kinase 1	0	2	17	19
Epithelial discoidin domain-containing receptor 1	0	3	17	20
Potassium voltage-gated channel subfamily H member 2	0	20	0	21
Mitogen-activated protein kinase kinase kinase kinase 2	0	1	17	18
Tyrosine-protein kinase Mer	0	3	14	17
Serine/threonine-protein kinase 4	0	1	17	18
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	17	18
Dual specificity mitogen-activated protein kinase kinase 5	0	0	17	17
Mitogen-activated protein kinase 7	0	0	17	17
Serine/threonine-protein kinase PAK 2	0	1	17	18
Serine/threonine-protein kinase 3	0	0	17	17
Mitogen-activated protein kinase kinase kinase 1	0	0	17	17
Integrin-linked protein kinase	0	0	17	17
Rho-associated protein kinase 1	0	0	17	17
Non-receptor tyrosine-protein kinase TNK1	0	0	17	17
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	2	17	19
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	1	17	18
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	17	17
Activin receptor type-2B	0	0	17	17
Bone morphogenetic protein receptor type-2	0	0	17	17
Protein-tyrosine kinase 6	0	2	17	19
cGMP-dependent protein kinase 1	0	0	17	17
Cyclin-dependent kinase 13	0	0	17	17
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	17	17
Protein-tyrosine kinase 2-beta	0	1	17	18
Maternal embryonic leucine zipper kinase	0	0	17	17
Structural maintenance of chromosomes protein 1A	0	0	17	17
Chromodomain-helicase-DNA-binding protein 4	0	0	17	17
Peroxisomal acyl-coenzyme A oxidase 1	0	0	15	15
Cyclin-dependent kinase 10	0	0	5	5
Ephrin type-A receptor 7	0	0	15	15
Delta(24)-sterol reductase	0	0	17	17
Ribosomal protein S6 kinase alpha-1	0	2	17	19
Dual specificity testis-specific protein kinase 1	0	0	15	15
Myosin light chain kinase, smooth muscle	0	0	17	17
Mitogen-activated protein kinase 11	0	1	17	18
Serine/threonine-protein kinase STK11	0	0	17	17
Serine/threonine-protein kinase N1	0	0	17	17
Serine/threonine-protein kinase N2	0	1	17	18
Mitogen-activated protein kinase 14	0	5	18	23
Calcium/calmodulin-dependent protein kinase type IV	0	0	17	17
Mitogen-activated protein kinase kinase kinase 11	0	1	17	18
MAP kinase-activated protein kinase 3	0	0	7	7
Discoidin domain-containing receptor 2	0	4	17	21
AP2-associated protein kinase 1	0	0	17	17
Myosin light chain kinase 3	0	0	17	17
Uncharacterized aarF domain-containing protein kinase 5	0	0	11	11
Putative heat shock protein HSP 90-beta 2	0	0	17	17
Rab-like protein 3	0	0	12	12
Serine/threonine-protein kinase MRCK alpha	0	0	17	17
Serine/threonine-protein kinase MRCK gamma	0	0	17	17
Acyl-CoA dehydrogenase family member 10	0	0	16	16
Serine/threonine-protein kinase N3	0	0	15	15
Serine/threonine-protein kinase ULK3	0	0	17	17
Uncharacterized protein FLJ45252	0	0	17	17
Acyl-CoA dehydrogenase family member 11	0	0	16	16
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	16	16
Serine/threonine-protein kinase MARK2	0	0	17	17
ATP-dependent RNA helicase DHX30	0	0	14	14
Serine/threonine-protein kinase TAO1	0	0	17	17
STE20-related kinase adapter protein alpha	0	0	17	17
Myosin-14	0	0	17	17
AarF domain-containing protein kinase 1	0	0	17	17
ATP-dependent RNA helicase DDX42	0	0	15	15
Mitogen-activated protein kinase kinase kinase kinase 3	0	1	17	18
MAP kinase-activated protein kinase 5	0	0	16	16
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	5	5
Misshapen-like kinase 1	0	1	17	18
Atypical kinase COQ8A, mitochondrial	0	0	17	17
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	17	17
Mitogen-activated protein kinase 15	0	0	17	17
Serine/threonine-protein kinase Nek9	0	0	17	17
ATP-dependent RNA helicase DDX1	0	0	17	17
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	17	17
Aurora kinase B	0	2	17	19
MAP/microtubule affinity-regulating kinase 4	0	0	17	17
Serine/threonine-protein kinase Nek1	0	0	17	17
PAS domain-containing serine/threonine-protein kinase	0	0	13	13
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	17	17
EKC/KEOPS complex subunit TP53RK	0	0	17	17
Dual specificity testis-specific protein kinase 2	0	0	10	10
SRSF protein kinase 1	0	1	10	11
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	4	17	21
Mitogen-activated protein kinase kinase kinase 5	0	0	17	17
Mitogen-activated protein kinase kinase kinase 3	0	0	17	17
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	17	17
Nucleolar GTP-binding protein 1	0	0	17	17
Serine/threonine-protein kinase D2	0	0	17	17
NUAK family SNF1-like kinase 2	0	0	16	16
RNA cytidine acetyltransferase	0	0	17	17
Serine/threonine-protein kinase SIK2	0	1	17	18
STE20-like serine/threonine-protein kinase	0	0	17	17
Serine/threonine-protein kinase TAO3	0	0	17	17
dCTP pyrophosphatase 1	0	0	17	17
Dual specificity protein kinase CLK4	0	0	15	15
Echinoderm microtubule-associated protein-like 4	0	3	2	6
Casein kinase I isoform gamma-1	0	0	17	17
Serine/threonine-protein kinase PAK 6	0	0	14	14
Phenylalanine--tRNA ligase beta subunit	0	0	17	17
BMP-2-inducible protein kinase	0	0	17	17
Obg-like ATPase 1	0	0	14	14
Midasin	0	0	17	17
Interleukin-1 receptor-associated kinase 4	0	1	17	18
Mitogen-activated protein kinase kinase kinase 20	0	0	17	17
Cyclin-dependent kinase 12	0	1	17	18
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	16	16
Serine/threonine-protein kinase pim-2	0	0	12	12
Serine/threonine-protein kinase 26	0	0	17	17
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	14	14
Serine/threonine-protein kinase NLK	0	0	17	17
5'-AMP-activated protein kinase subunit gamma-2	0	0	17	18
Serine/threonine-protein kinase TBK1	0	2	17	19
Septin-9	0	0	17	17
Ribosomal protein S6 kinase alpha-6	0	0	17	17
TRAF2 and NCK-interacting protein kinase	0	0	17	17
Serine/threonine-protein kinase TAO2	0	0	17	17
ALK tyrosine kinase receptor	0	10	16	27
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	12	2	16
Serine/threonine-protein kinase ICK	0	0	16	16
RAC-gamma serine/threonine-protein kinase	0	1	17	18
Serine/threonine-protein kinase SIK3	0	1	17	18
Mitogen-activated protein kinase kinase kinase 2	0	0	17	17
Thyroid hormone receptor-associated protein 3	0	0	16	16
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	14	14
Mitogen-activated protein kinase kinase kinase kinase 5	0	1	17	18
Receptor-interacting serine/threonine-protein kinase 3	0	1	17	18
Serine/threonine-protein kinase MRCK beta	0	0	17	17
Interleukin-1 receptor-associated kinase 3	0	0	17	17
Casein kinase I isoform gamma-3	0	0	17	17
Mitogen-activated protein kinase kinase kinase 4	0	0	17	17
Chain A, Protein (glycogen Phosphorylase)	0	1	0	1
Leukotriene C4 synthase	0	0	10	10
Glycogen synthase kinase-3 beta	0	1	0	1
[Tau protein] kinase	0	1	0	1
Serine/threonine-protein kinase 25	0	0	10	10
Serine/threonine-protein kinase RIO3	0	0	10	10
Dual specificity mitogen-activated protein kinase kinase 7	0	0	10	10
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	10	12
Peripheral plasma membrane protein CASK	0	0	10	10
Serine/threonine-protein kinase DCLK1	0	0	10	10
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	10	11
Muscle, skeletal receptor tyrosine-protein kinase	0	0	10	10
Mitogen-activated protein kinase 13	0	1	10	11
3-phosphoinositide-dependent protein kinase 1	0	1	10	11
Mitogen-activated protein kinase kinase kinase 13	0	0	10	10
Death-associated protein kinase 3	0	0	10	10
NUAK family SNF1-like kinase 1	0	0	10	10
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	10	10
Cyclin-T1	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	0	0	2
Tyrosine-protein kinase JAK2	0	5	12	17
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	10	10
Cyclin-K	0	1	0	1
Serine/threonine-protein kinase PAK 3	0	0	10	10
Serine/threonine-protein kinase 17B	0	0	10	10
Cyclin-dependent kinase 14	0	0	10	10
G2/mitotic-specific cyclin-B2	0	1	0	2
Serine/threonine-protein kinase OSR1	0	0	10	10
Serine/threonine-protein kinase Chk2	0	0	10	10
G1/S-specific cyclin-E2	0	2	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	3	10	13
Vitamin K-dependent protein C	0	1	0	1
Protein kinase C gamma type	0	4	1	5
Protein kinase C alpha type	0	2	0	2
Macrophage colony-stimulating factor 1 receptor	0	8	10	18
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
Wee1-like protein kinase 2	0	0	10	10
Uncharacterized serine/threonine-protein kinase SBK3	0	0	10	10
Myosin light chain kinase, smooth muscle	0	0	7	7
Insulin receptor-related protein	0	0	10	10
G2/mitotic-specific cyclin-B1	0	3	0	4
G2/mitotic-specific cyclin-B	0	1	0	1
Platelet-derived growth factor receptor alpha	0	9	11	20
Vascular endothelial growth factor receptor 1	0	9	10	19
Glycogen synthase kinase-3 beta	0	2	0	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	10	10
Cyclin-A2	0	3	0	4
Serine/threonine-protein kinase MAK	0	0	10	10
Cyclin-dependent kinase 11B	0	0	10	10
Receptor tyrosine-protein kinase erbB-3	0	3	10	13
Nucleoside diphosphate kinase B	0	0	3	3
Dual specificity protein kinase CLK1	0	1	0	1
G1/S-specific cyclin-D1	0	3	0	4
Protein kinase C eta type	0	3	11	14
G1/S-specific cyclin-E1	0	3	0	3
Activin receptor type-2A	0	0	10	10
Ephrin type-A receptor 3	0	0	10	10
Ephrin type-A receptor 8	0	0	10	10
Leukocyte tyrosine kinase receptor	0	0	10	10
G1/S-specific cyclin-D2	0	1	0	2
G1/S-specific cyclin-D3	0	1	0	2
Tyrosine-protein kinase receptor UFO	0	2	10	12
Mitogen-activated protein kinase 4	0	0	10	10
G protein-coupled receptor kinase 4	0	0	10	10
Prostaglandin G/H synthase 2	0	8	11	20
Tyrosine-protein kinase receptor Tie-1	0	0	10	10
Vascular endothelial growth factor receptor 3	0	7	10	17
Serine/threonine-protein kinase receptor R3	0	0	11	11
Megakaryocyte-associated tyrosine-protein kinase	0	0	10	10
Tyrosine-protein kinase TXK	0	3	11	14
Tyrosine-protein kinase ZAP-70	0	4	10	14
Dual specificity mitogen-activated protein kinase kinase 4	0	0	11	11
Cyclin-dependent kinase 8	0	1	10	11
Tyrosine-protein kinase Blk	0	2	11	13
Cytoplasmic tyrosine-protein kinase BMX	0	4	11	15
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	11	11
Cyclin-H	0	1	0	1
CDK-activating kinase assembly factor MAT1	0	1	0	1
Serine/threonine-protein kinase Nek4	0	0	10	10
Tyrosine-protein kinase JAK3	0	5	11	16
Death-associated protein kinase 1	0	0	10	10
Mitogen-activated protein kinase 12	0	1	10	11
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	10	11
Ephrin type-B receptor 1	0	0	10	10
Hormonally up-regulated neu tumor-associated kinase	0	0	10	10
Serine/threonine-protein kinase SIK1	0	2	10	12
Receptor-interacting serine/threonine-protein kinase 4	0	0	10	10
Cell division control protein 2 homolog	0	0	10	10
Calcium-dependent protein kinase 1	0	0	10	10
Protein kinase C gamma type	0	2	0	2
Tubulin alpha-1A chain	0	0	7	7
Protein kinase C beta type	0	2	0	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	10	10
SRSF protein kinase 2	0	0	10	10
Cyclin-A1	0	3	0	4
Mitogen-activated protein kinase kinase kinase 9	0	1	10	11
Serine/threonine-protein kinase PknB	0	0	10	10
Cyclin-dependent kinase-like 1	0	0	10	10
Cyclin homolog	0	1	0	1
Protein kinase C epsilon type	0	4	11	15
Angiopoietin-1 receptor	0	5	10	15
Mitogen-activated protein kinase kinase kinase 10	0	1	10	11
Tyrosine-protein kinase receptor TYRO3	0	1	10	11
Tyrosine-protein kinase ITK/TSK	0	3	11	14
Myotonin-protein kinase	0	0	10	10
Mitogen-activated protein kinase kinase kinase 12	0	0	10	10
Serine/threonine-protein kinase PAK 1	0	1	10	11
cGMP-dependent protein kinase 2	0	0	10	10
Serine/threonine-protein kinase PRP4 homolog	0	0	10	10
Receptor-interacting serine/threonine-protein kinase 1	0	2	10	12
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	10	11
Calcium/calmodulin-dependent protein kinase type 1	0	0	10	10
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Serine/threonine-protein kinase D1	0	4	11	15
Serine/threonine-protein kinase 38	0	0	13	13
Receptor tyrosine-protein kinase erbB-4	0	3	11	14
Ribosomal protein S6 kinase alpha-2	0	0	10	10
Rhodopsin kinase GRK1	0	0	10	10
NT-3 growth factor receptor	0	0	10	10
BDNF/NT-3 growth factors receptor	0	3	10	13
Mitogen-activated protein kinase 6	0	0	10	10
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	10	10
La-related protein 7	0	1	0	1
Serine/threonine-protein kinase SBK1	0	0	10	10
Mitogen-activated protein kinase kinase kinase 19	0	0	10	10
Serine/threonine-protein kinase TNNI3K	0	1	10	11
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Protein kinase C eta type	0	2	0	2
Serine/threonine-protein kinase Nek5	0	0	10	10
Dual serine/threonine and tyrosine protein kinase	0	0	10	10
Mitogen-activated protein kinase kinase kinase 15	0	0	10	10
Serine/threonine-protein kinase tousled-like 2	0	0	10	10
Serine/threonine-protein kinase 32C	0	0	10	10
Serine/threonine-protein kinase VRK2	0	0	10	10
Myosin light chain kinase family member 4	0	0	10	10
Homeodomain-interacting protein kinase 1	0	1	10	11
Calcium/calmodulin-dependent protein kinase type 1D	0	1	10	11
Cyclin-dependent kinase-like 3	0	0	10	10
Serine/threonine-protein kinase BRSK2	0	0	10	10
Serine/threonine-protein kinase NIM1	0	0	10	10
Serine/threonine-protein kinase ULK2	0	0	10	10
Serine/threonine-protein kinase DCLK2	0	0	10	10
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	10	10
Casein kinase I isoform alpha-like	0	0	10	10
Homeodomain-interacting protein kinase 4	0	1	10	11
Myosin-IIIa	0	0	10	10
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	10	10
Serine/threonine-protein kinase Nek11	0	0	10	10
Serine/threonine-protein kinase BRSK1	0	0	10	10
Serine/threonine-protein kinase 35	0	0	10	10
Serine/threonine-protein kinase Nek7	0	0	15	15
Rhodopsin kinase GRK7	0	0	10	10
Serine/threonine-protein kinase 32A	0	0	10	10
G2/mitotic-specific cyclin-B3	0	1	0	2
Myosin-IIIb	0	0	10	10
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	10	10
Cyclin-dependent kinase-like 2	0	0	10	10
Serine/threonine-protein kinase Sgk3	0	0	10	10
Atypical kinase COQ8B, mitochondrial	0	0	10	10
Calcium/calmodulin-dependent protein kinase type 1G	0	0	13	13
Cyclin-dependent kinase 15	0	0	10	10
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	10	10
Serine/threonine-protein kinase RIO1	0	0	10	10
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	10	10
Serine/threonine-protein kinase RIO2	0	0	10	10
Cyclin-dependent kinase 19	0	1	10	11
Transient receptor potential cation channel subfamily M member 6	0	0	10	10
Testis-specific serine/threonine-protein kinase 1	0	1	10	11
Serine/threonine-protein kinase 33	0	0	10	10
Serine/threonine-protein kinase DCLK3	0	0	10	10
Cyclin-dependent kinase 1	0	1	0	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	10	10
Homeodomain-interacting protein kinase 2	0	1	10	11
Tyrosine-protein kinase Srms	0	0	10	10
Homeodomain-interacting protein kinase 3	0	1	10	11
MAP kinase-interacting serine/threonine-protein kinase 2	0	2	10	12
Serine/threonine-protein kinase Nek6	0	0	10	10
SNF-related serine/threonine-protein kinase	0	0	10	10
Serine/threonine-protein kinase LATS2	0	0	10	10
Serine/threonine-protein kinase 36	0	0	10	10
Isoleucine--tRNA ligase, mitochondrial	0	0	12	12
Serine/threonine-protein kinase 32B	0	0	10	10
Serine/threonine-protein kinase MARK1	0	0	10	10
Serine/threonine-protein kinase PAK 5	0	0	10	10
eIF-2-alpha kinase GCN2	0	0	10	10
Serine/threonine-protein kinase 17A	0	0	10	10
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	10	10
Ephrin type-A receptor 6	0	0	10	10
Death-associated protein kinase 2	0	0	10	10
Serine/threonine-protein kinase tousled-like 1	0	0	10	10
Long-chain-fatty-acid--CoA ligase 5	0	0	13	13
SRSF protein kinase 3	0	0	10	10
Cyclin-dependent kinase 11A	0	0	10	10
Aurora kinase C	0	1	10	11
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	10	11
Protein kinase C theta type	0	2	0	2
Serine/threonine-protein kinase 38-like	0	0	12	12
Microtubule-associated serine/threonine-protein kinase 1	0	0	10	10
Serine/threonine-protein kinase 24	0	1	13	14
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
G	36	0	0	36
ATP-binding cassette sub-family C member 3	0	46	0	46
Multidrug resistance-associated protein 4	0	46	0	48
Interferon beta	57	0	0	57
HLA class I histocompatibility antigen, B alpha chain	36	0	0	36
Cytochrome P450 2C9	0	16	1	19
Amine oxidase [flavin-containing] A	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	3	0	4
Inositol hexakisphosphate kinase 1	36	0	0	36
Canalicular multispecific organic anion transporter 1	0	46	0	47
cytochrome P450 2C9, partial	36	0	0	36
DNA polymerase kappa isoform 1	14	0	0	14
histone acetyltransferase KAT2A isoform 1	20	0	0	20
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	2	2	4
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
GLS protein	20	0	0	20
alpha-galactosidase	5	0	0	5
muscarinic acetylcholine receptor M1	11	0	0	11
lethal factor (plasmid)	11	0	0	11
Cytochrome P450 3A4	0	22	4	31
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	1	1	4
Cationic amino acid transporter 3	0	1	0	1
PPM1D protein	33	0	0	33
thioredoxin glutathione reductase	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	17	0	0	17
Cytochrome P450 2B6	0	5	0	6
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Polyphenol oxidase 2	0	3	0	5
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	8	1	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	3	0	3
DNA polymerase beta	7	0	0	7
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	6	0	8
Muscarinic acetylcholine receptor M2	0	9	1	13
Muscarinic acetylcholine receptor M4	0	10	1	13
Muscarinic acetylcholine receptor M1	0	5	1	8
Muscarinic acetylcholine receptor M3	0	5	1	8
Muscarinic acetylcholine receptor M4	0	5	1	8
Muscarinic acetylcholine receptor M5	0	5	1	8
Muscarinic acetylcholine receptor M5	0	6	1	9
Muscarinic acetylcholine receptor M2	0	5	1	9
Muscarinic acetylcholine receptor M1	0	10	1	14
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	8	1	11
Alpha-1D adrenergic receptor	0	8	0	8
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	0	1	2
Muscarinic acetylcholine receptor	0	1	1	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	2	0	2
cytochrome P450 2D6	29	0	0	29
tyrosine-protein kinase Yes	12	0	0	12
Cytochrome P450 2D6	0	9	3	12
interleukin 8	11	0	0	11
Fumarate hydratase	31	0	0	31
polyprotein	31	0	0	31
Bloom syndrome protein isoform 1	16	0	0	16
peripheral myelin protein 22 isoform 1	13	0	0	13
hemoglobin subunit beta	6	0	0	6
huntingtin isoform 2	11	0	0	11
ras-related protein Rab-9A	7	0	0	7
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
Nuclear receptor ROR-gamma	13	1	1	15
Multidrug and toxin extrusion protein 1	0	6	0	6
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
P53	1	0	0	1
muscleblind-like protein 1 isoform 1	12	0	0	12
Bile salt export pump	0	6	0	6
Protein-arginine deiminase type-4	0	5	0	5
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Interstitial collagenase	0	2	0	2
Low affinity immunoglobulin epsilon Fc receptor	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	4	2	6
Matrilysin	0	2	0	2
Matrix metalloproteinase-9	0	5	0	5
Neutrophil collagenase	0	3	0	3
Metabotropic glutamate receptor 5	0	1	0	1
Collagenase 3	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Matrix metalloproteinase-14	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	2	1	0	3
Snake venom metalloproteinase BaP1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Histone deacetylase 3	0	10	2	15
Leukotriene A-4 hydrolase	0	3	0	3
Cytochrome P450 3A5	0	2	0	3
Histone deacetylase 4	0	9	2	14
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Histone deacetylase 1	0	11	3	17
Histone deacetylase 7	0	9	3	15
Histone deacetylase 2	0	11	3	17
Polyamine deacetylase HDAC10	0	9	2	14
Histone deacetylase 11	0	9	2	14
Histone deacetylase 8	0	11	3	17
Histone deacetylase 6	0	10	3	16
Histone deacetylase 9	0	9	2	14
Histone deacetylase 5	0	9	2	14
Histone deacetylase	0	2	0	2
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	4	0	7
Prothrombin	0	1	0	3
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 1	0	18	0	21
Carbonic anhydrase 2	0	19	1	24
Carbonic anhydrase 3	0	3	0	6
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	2
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	11	0	14
Carbonic anhydrase 6	0	3	0	6
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	4	0	5
Carbonic anhydrase 5A, mitochondrial	0	9	0	12
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	4	0	7
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	2	0	2
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	11	0	15
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	2	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	6	0	9
Carbonic anhydrase 14	0	4	0	7
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	0	8
Membrane-associated progesterone receptor component 1	0	0	10	10
Nucleophosmin	0	3	0	3
Glycogen phosphorylase, muscle form	0	1	0	1
Tyrosine-protein kinase Blk	0	2	0	2
Platelet-derived growth factor receptor alpha	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Synaptic vesicular amine transporter	0	2	0	2
Platelet-derived growth factor receptor beta	0	1	0	1
Angiotensin-converting enzyme	0	2	0	3
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
DNA topoisomerase	0	1	0	1
putative alpha-glucosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	12	0	0	12
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
relaxin receptor 1 isoform 1	1	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	9
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
Type-2 restriction enzyme HindIII	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
Inositol monophosphatase 1	9	0	0	9
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	5	0	5
DNA topoisomerase type IB small subunit	0	0	1	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Protein phosphatase 1B	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	4	0	6
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit	0	1	0	1
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B	0	1	0	1
vitamin D3 receptor isoform VDRA	18	0	0	18
histone-lysine N-methyltransferase 2A isoform 2 precursor	7	0	0	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	7	0	0	7
USP1 protein, partial	27	0	0	27
luciferase	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	14	0	0	14
eyes absent homolog 2 isoform a	4	0	0	4
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Tyrosine-protein phosphatase 1	0	2	0	2
Alpha-synuclein	11	3	1	15
C-terminal-binding protein 1	3	0	0	3
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	4	0	4
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
interferon gamma precursor	0	0	0	5
prostaglandin E2 receptor EP2 subtype	1	0	0	2
Prostaglandin E synthase	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Procathepsin L	0	1	4	5
Aldo-keto reductase family 1 member B1	0	12	0	12
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	7	0	8
Quinolone resistance protein NorA	0	3	0	3
Beta-3 adrenergic receptor	0	4	0	4
Alpha-1B adrenergic receptor	0	13	0	13
Calpain-2 catalytic subunit	0	1	0	1
5-hydroxytryptamine receptor 1A	0	8	0	8
D(1A) dopamine receptor	0	6	0	6
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	7
Sodium-dependent noradrenaline transporter	0	12	2	14
Cruzipain	0	3	0	3
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Sodium-dependent serotonin transporter	0	8	0	8
Delta-type opioid receptor	0	3	1	5
Delta-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	9	1	13
Bifunctional epoxide hydrolase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase	0	7	0	10
Alpha-1A adrenergic receptor	0	14	0	14
Urotensin-2 receptor	0	1	0	1
Carbonic anhydrase	0	1	0	4
Ras-related protein Rab-2A	0	0	1	1
D(2) dopamine receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	4
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Sodium-dependent dopamine transporter	0	6	0	6
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	4	0	4
Delta carbonic anhydrase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase	0	1	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Rap guanine nucleotide exchange factor 4	3	0	0	3
Carbonic anhydrase 4	0	2	0	2
P2Y purinoceptor 12	0	1	0	1
ATP-dependent translocase ABCB1	0	15	5	31
Replicase polyprotein 1ab	0	6	5	11
Transcription factor ETV6	0	1	0	1
transcriptional regulator ERG isoform 3	8	0	0	8
ORF73	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	3
DNA gyrase subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	8	1	10
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
streptokinase A precursor	0	0	5	5
Solute carrier organic anion transporter family member 1B3	0	7	0	8
Solute carrier organic anion transporter family member 1B1	0	6	0	7
endonuclease IV	5	0	0	5
PAX8	0	0	0	2
nuclear receptor subfamily 0 group B member 1	0	2	0	2
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	2	0	2
caspase-1 isoform alpha precursor	3	0	0	3
Solute carrier family 22 member 3	0	4	0	4
Tubulin alpha-1A chain	0	4	2	7
Tubulin beta chain	0	4	2	6
Plasma kallikrein	0	0	0	4
Tubulin beta-4A chain	0	3	3	8
ATP-dependent translocase ABCB1	0	6	0	6
Tubulin beta chain	0	3	3	8
Tubulin alpha-3C chain	0	3	3	8
ATP-dependent translocase ABCB1	0	7	0	8
Tubulin alpha-1B chain	0	3	3	8
Tubulin alpha-4A chain	0	3	3	8
Tubulin beta-4B chain	0	3	3	8
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	4	3	9
Tubulin beta-2A chain	0	3	3	8
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	3	3	8
Tubulin beta-2B chain	0	4	1	7
Tubulin alpha-3E chain	0	3	3	8
Tubulin alpha-1A chain	0	3	3	8
Similar to alpha-tubulin isoform 1	0	3	1	6
Similar to alpha-tubulin isoform 1	0	3	0	5
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	3	3	8
Tubulin beta-6 chain	0	3	3	8
Tubulin beta-2B chain	0	3	3	8
Tubulin beta-1 chain	0	3	3	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	0	1	0	1
Sodium-dependent phosphate transport protein 2B	0	1	0	1
Tyrosine-protein kinase ABL1	0	3	0	3
HLA class II histocompatibility antigen gamma chain	0	1	0	1
Androgen receptor	0	7	2	9
ALK tyrosine kinase receptor	0	1	0	1
Angiopoietin-1 receptor	0	1	0	1
Lysine--tRNA ligase	0	1	0	1
Macrophage-stimulating protein receptor	0	1	0	1
Mixed lineage kinase domain-like protein	0	0	1	1
Aurora kinase A-interacting protein	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Nrf2	2	0	0	2
alkaline phosphatase, intestinal	0	1	1	2
PINK1	3	0	0	3
toll-like receptor 9	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
TPA: protein transporter TIM10	0	2	0	2
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	1	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	1	2
perilipin-1	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	5	1	0	6
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	4	0	0	4
Acetylcholinesterase	0	3	0	3
Lysine-specific histone demethylase 1A	0	3	0	3
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Amyloid-beta precursor protein	2	5	0	8
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	2
Cholinesterase	0	2	0	2
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
60 kDa chaperonin	0	5	0	5
Replicase polyprotein 1ab	0	1	5	6
Microtubule-associated protein tau	0	4	1	6
60 kDa heat shock protein, mitochondrial	0	6	0	6
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	2	0	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Amine oxidase [flavin-containing] A	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Acetylcholinesterase	0	8	0	8
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	6	0	6
Amine oxidase [flavin-containing] B	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Caspase-7	2	0	0	2
Beta-secretase 1	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	6	0	6
Cholinesterase	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	0	1	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Thiosulfate sulfurtransferase	0	6	0	6
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
60 kDa chaperonin	0	6	0	6
10 kDa chaperonin	0	6	0	6
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Smoothened homolog	0	2	1	3
Sonic hedgehog protein	0	2	0	3
Sonic hedgehog protein	0	2	1	3
Smoothened homolog	0	4	3	7
Protein-S-isoprenylcysteine O-methyltransferase	0	1	0	1
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	4	0	8
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	5	0	7
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	2
Deoxynucleoside kinase	0	1	0	1
Isocitrate lyase	0	1	0	1
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
GALC protein	7	0	0	7
Spike glycoprotein	0	0	4	4
Transmembrane protease serine 2	0	0	4	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Transthyretin	0	1	1	3
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Replicase polyprotein 1a	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Cytochrome P450 2A6	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Sodium channel protein type 5 subunit alpha	0	3	0	3
Breakpoint cluster region protein	0	1	0	1
Protein cereblon	0	8	4	18
Angiotensin-converting enzyme 2	0	0	5	5
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
NF-kappa-B essential modulator	0	1	0	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
P2Y purinoceptor 2	0	0	1	1
serine/threonine-protein kinase PLK1	9	0	0	9
Nuclear receptor subfamily 1 group I member 2	0	1	5	6
Glucocorticoid receptor	0	14	3	22
Glycine receptor subunit alpha-1	0	14	0	14
Beta-1 adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	9	1	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
D(2) dopamine receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	6	0	6
Glycine receptor subunit beta	0	14	0	14
Substance-K receptor	0	6	0	6
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Thromboxane-A synthase	0	2	0	2
Mu-type opioid receptor	0	6	1	8
D(3) dopamine receptor	0	8	0	8
Vasopressin V1a receptor	0	2	0	2
Delta-type opioid receptor	0	9	1	11
Kappa-type opioid receptor	0	6	1	8
5-hydroxytryptamine receptor 6	0	8	0	8
Aldehyde oxidase	0	2	0	2
UDP-glucose 4-epimerase	0	1	0	1
Cysteinyl leukotriene receptor 1	0	2	0	2
Solute carrier family 22 member 2	0	2	0	4
Thromboxane A2 receptor	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	3	1	4
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 6	0	2	0	5
Solute carrier family 22 member 7	0	0	0	3
Solute carrier family 22 member 8	0	1	0	5
Solute carrier organic anion transporter family member 2A1	0	1	0	3
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier family 22 member 11	0	0	0	4
Solute carrier family 22 member 7	0	0	0	3
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Serum paraoxonase/arylesterase 1	0	5	0	5
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
Thymidylate kinase	0	2	0	2
Uridine phosphorylase 1	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	2
Genome polyprotein	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	2	0	3
Serine/threonine-protein kinase B-raf	0	2	0	2
Motilin receptor	0	0	1	1
acid sphingomyelinase	3	0	0	3
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
30S ribosomal protein S6	0	2	1	3
30S ribosomal protein S7	0	2	1	3
50S ribosomal protein L15	0	2	1	3
Albumin	0	3	7	10
50S ribosomal protein L10	0	2	1	3
50S ribosomal protein L11	0	2	1	3
50S ribosomal protein L7/L12	0	2	1	3
50S ribosomal protein L19	0	2	1	3
50S ribosomal protein L1	0	2	1	3
50S ribosomal protein L20	0	2	1	3
50S ribosomal protein L27	0	2	1	3
50S ribosomal protein L28	0	2	1	3
50S ribosomal protein L29	0	2	1	3
50S ribosomal protein L31	0	2	1	3
50S ribosomal protein L31 type B	0	2	1	3
50S ribosomal protein L32	0	2	1	3
50S ribosomal protein L33	0	2	1	3
50S ribosomal protein L34	0	2	1	3
50S ribosomal protein L35	0	2	1	3
50S ribosomal protein L36	0	2	1	3
30S ribosomal protein S10	0	2	1	3
30S ribosomal protein S11	0	2	1	3
30S ribosomal protein S12	0	2	1	3
30S ribosomal protein S13	0	2	1	3
30S ribosomal protein S16	0	2	1	3
30S ribosomal protein S18	0	2	1	3
30S ribosomal protein S19	0	2	1	3
30S ribosomal protein S20	0	2	1	3
30S ribosomal protein S2	0	2	1	3
30S ribosomal protein S3	0	2	1	3
30S ribosomal protein S4	0	2	1	3
30S ribosomal protein S5	0	2	1	3
30S ribosomal protein S8	0	2	1	3
30S ribosomal protein S9	0	2	1	3
50S ribosomal protein L13	0	2	1	3
50S ribosomal protein L14	0	2	1	3
50S ribosomal protein L16	0	2	1	3
50S ribosomal protein L23	0	2	1	3
30S ribosomal protein S15	0	2	1	3
50S ribosomal protein L17	0	2	1	3
50S ribosomal protein L21	0	2	1	3
50S ribosomal protein L30	0	2	1	3
50S ribosomal protein L6	0	2	1	3
30S ribosomal protein S14	0	2	1	3
30S ribosomal protein S17	0	2	1	3
30S ribosomal protein S1	0	2	1	3
50S ribosomal protein L18	0	2	1	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 2J2	0	5	0	5
50S ribosomal protein L2	0	2	1	3
50S ribosomal protein L3	0	2	1	3
50S ribosomal protein L24	0	2	1	3
50S ribosomal protein L4	0	2	1	3
50S ribosomal protein L22	0	2	1	3
50S ribosomal protein L5	0	2	1	3
30S ribosomal protein S21	0	2	1	3
50S ribosomal protein L25	0	2	1	3
Cytochrome P450 1B1	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	0	1
50S ribosomal protein L36 2	0	2	1	3
Regulatory protein E2	0	0	1	1
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
Glutamate receptor ionotropic, NMDA 1	0	0	0	4
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	4
Glutamate receptor ionotropic, NMDA 2B	0	1	0	6
Glutamate receptor ionotropic, NMDA 2C	0	0	0	4
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	4
Glutamate receptor ionotropic, NMDA 3B	0	0	0	4
Glutamate receptor ionotropic, NMDA 3A	0	0	0	4
Luciferin 4-monooxygenase	0	1	1	2
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	0	2	0	2
Vesicular glutamate transporter 3	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Thymidine phosphorylase	0	0	0	2
Thymidine kinase	0	0	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	1	2
Skn7p	0	0	0	2
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	3
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
5'-nucleotidase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Vpr	4	0	0	4
Solute carrier family 22 member 8	0	0	0	1
D(1A) dopamine receptor	5	0	0	5
Cocaine esterase	0	1	0	2
Arylacetamide deacetylase	0	0	0	2
Arylacetamide deacetylase	0	0	0	2
Arylacetamide deacetylase	0	0	0	2
Estrogen receptor	0	1	1	3
Progesterone receptor	0	6	1	8
Steroid hormone receptor ERR1	0	2	0	2
Beta-lactamase TEM	0	1	0	2
Bile acid receptor	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	3	0	3
Albumin	0	0	2	2
Sodium-dependent dopamine transporter	0	2	0	2
epidermal growth factor receptor isoform a precursor	1	1	0	2
Cytochrome P450 2E1	0	1	0	1
Cytochrome P450 2C8	0	4	0	6
Mitogen-activated protein kinase kinase kinase 8	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain E, Fibrin beta chain	0	2	0	2
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
WRN	3	0	0	3
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
hypothetical protein, conserved	3	0	0	3
pyruvate kinase	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
CDK5	0	0	0	1
serine-protein kinase ATM isoform a	2	0	0	2
major prion protein preproprotein Prp precursor	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
DNA polymerase eta isoform 1	6	0	0	6
Vif	0	1	0	1
Tat	0	1	0	1
endoribonuclease toxin MazF	0	0	1	1
Pyruvate kinase PKM	0	1	0	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
phosphoglycerate kinase	4	0	0	4
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Neuraminidase	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	5	0	0	5
Spike glycoprotein	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Retinoic acid receptor RXR-alpha	0	3	5	9
Cannabinoid receptor 1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	2	3
Cannabinoid receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	2	3
Gamma-aminobutyric acid receptor subunit beta-2	0	1	2	3
G-protein coupled bile acid receptor 1	0	1	0	1
Platelet glycoprotein VI	0	1	1	2
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	2	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Urease subunit alpha	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Urease subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	3
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	2	1	4
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Cereblon isoform 4	0	4	0	4
DNA-binding protein Ikaros	0	0	2	7
DNA damage-binding protein 1	0	3	2	5
Zinc finger protein Aiolos	0	0	2	2
Kinesin-1 heavy chain	0	2	0	2
Nuclear receptor coactivator 4	0	1	0	1
Coiled-coil domain-containing protein 6	0	2	0	2
Leukotriene B4 receptor 1	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
dopamine D1 receptor	4	0	0	4
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	4
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
5'-nucleotidase	0	2	0	2
Phospholipase A-2-activating protein	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
[tau protein] kinase	0	1	0	1
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	1	2
5-hydroxytryptamine receptor 2C	0	2	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Androgen receptor	0	0	1	1
Histamine H2 receptor	0	8	0	8
5-hydroxytryptamine receptor 1B	0	5	0	5
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
ClpP	2	0	0	2
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A2	0	1	0	3
Myeloperoxidase	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	1	2
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	1	2
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	1	2
Beta-lactamase	0	0	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	2	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	7	0	8
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	3	2	5
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	2	0	2
Dihydrofolate reductase	0	4	0	4
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Bifunctional purine biosynthesis protein ATIC	0	4	0	4
Multidrug resistance-associated protein 1	0	3	1	6
Kappa-type opioid receptor	0	3	1	5
Reduced folate transporter	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	3	0	4
Multidrug resistance associated protein	0	1	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	2	2
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Multidrug transporter MdfA	0	2	0	2
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
DNA polymerase III, partial	2	0	0	2
nonstructural protein 1	0	1	0	1
LANA	0	0	0	1
phospholipase A2, group III	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Ornithine decarboxylase	1	0	0	2
Angiotensin-converting enzyme	0	4	0	4
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Single-stranded DNA cytosine deaminase	1	0	0	1
P2Y purinoceptor 12	0	2	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	0	1	1
Kappa-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Kappa-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Chain A, SusD homolog	0	0	1	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Galectin-1	0	0	1	1
Galectin-3	0	0	1	1
Galectin-7	0	0	1	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	4	0	4
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
Platelet-derived growth factor receptor beta	0	3	0	3
Platelet-derived growth factor receptor alpha	0	2	0	2
Putative nucleoside diphosphate kinase	0	0	2	2
von Hippel-Lindau disease tumor suppressor	0	1	0	1
Dipeptidyl peptidase 1	0	1	0	1
Epidermal growth factor receptor	0	2	0	2
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Integrin alpha-V	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	2	0	2
Bcl-2-like protein 1	0	1	0	1
Beta-tubulin	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	3	0	4
Farnesyl pyrophosphate synthase	0	4	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	3	0	3
Receptor protein-tyrosine kinase	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Peroxiredoxin-like 2A	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	4
SLC16A10 protein	0	0	0	3
Carbonic anhydrase-like protein, putative	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
Carbonic anhydrase 13	0	1	0	3
Programmed cell death protein 1	0	1	0	1
E3 ubiquitin-protein ligase ZFP91	0	0	0	1
Programmed cell death 1 ligand 1	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
N	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	3
Toll-like receptor 7	0	0	1	3
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Met repressor	0	0	2	2
Protein arginine N-methyltransferase 5	0	0	1	1
Histone H3K27 methylase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	0	1	2
S-adenosylmethionine decarboxylase proenzyme	0	1	0	2
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
Methylosome protein 50	0	0	1	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET	0	1	0	1
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET	0	1	0	1
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	2
vasopressin V1a receptor	0	0	1	1
oxytocin receptor	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
Vascular endothelial growth factor receptor 2	0	2	0	2
Vascular endothelial growth factor receptor 1	0	1	0	1
Vascular endothelial growth factor receptor 2	0	3	0	3
1,25-dihydroxyvitamin D-3 receptor	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Regulatory-associated protein of mTOR	0	1	0	1
Target of rapamycin complex subunit LST8	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Carbonic anhydrase	0	3	0	3
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
melanocortin receptor 4	0	1	1	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Cyclin-C	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Protein delta homolog 1	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
B2 bradykinin receptor	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Beta-lactamase	0	1	0	1
Zinc finger protein GLI1	0	1	0	1
Zinc finger protein GLI2	0	1	0	1
Malate dehydrogenase	0	1	0	1
Aldo-keto reductase family 1 member B10	0	1	0	1
Complement C5	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Chain A, FOCAL ADHESION KINASE 1	0	1	0	1
Chain A, FOCAL ADHESION KINASE 1	0	1	0	1
Chain A, FOCAL ADHESION KINASE 1	0	1	0	1
Chain A, FOCAL ADHESION KINASE 1	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Transcriptional activator protein LuxR	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Substance-P receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 3	0	2	0	2
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Estrogen receptor beta	0	0	1	2
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Cytochrome P450 2B1	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Thymidine kinase	0	0	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain B, Odorant-binding Protein	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Secreted chorismate mutase	0	1	0	1
Heat sensitive channel TRPV3	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Envelope glycoprotein	0	0	2	2
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
Histone deacetylase 1	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Nuclear receptor corepressor 1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Protein Tat	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Apoptosis regulator BAX	0	0	1	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	1	3
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Butyrophilin subfamily 3 member A1	0	0	1	2
Farnesyl diphosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Pleural Effusion, Malignant

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (790)

Protein Targets (2,123)

Pleural Effusion, Malignant

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (790)

Drugs Studied (326)

Protein Targets (2,123)