Roles > bridged diphenyl acaricide
Page last updated: 2024-08-05 15:18:07

bridged diphenyl acaricide

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ChEBI ID: 39412

Members (1)

MemberDefinitionClass
ddtA chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide.DDT

Research

Studies (8,017)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19904,729 (58.99)18.7374
1990's539 (6.72)18.2507
2000's1,180 (14.72)29.6817
2010's1,269 (15.83)24.3611
2020's300 (3.74)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials14 (0.16%)5.53%
Reviews355 (4.05%)6.00%
Case Studies27 (0.31%)4.05%
Observational3 (0.03%)0.25%
Other8,361 (95.45%)84.16%

Protein Targets (59)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency25.118911
activating transcription factor 6Homo sapiens (human)Potency50.836625
AR proteinHomo sapiens (human)Potency27.4652612
aryl hydrocarbon receptorHomo sapiens (human)Potency69.078211
caspase-3Cricetulus griseus (Chinese hamster)Potency69.078211
Caspase-7Cricetulus griseus (Chinese hamster)Potency69.078211
Cellular tumor antigen p53Homo sapiens (human)Potency51.640736
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency31.622811
Chain A, CruzipainTrypanosoma cruziPotency31.622811
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency44.668411
cytochrome P450 2C9, partialHomo sapiens (human)Potency2.187611
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency20.942122
estrogen nuclear receptor alphaHomo sapiens (human)Potency34.5665917
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency48.945425
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency47.4865614
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency28.183811
farnesoid X nuclear receptorHomo sapiens (human)Potency33.761046
GVesicular stomatitis virusPotency2.187611
gemininHomo sapiens (human)Potency18.837511
GLI family zinc finger 3Homo sapiens (human)Potency21.431324
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency42.6082410
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency69.078211
heat shock protein beta-1Homo sapiens (human)Potency57.231424
Histone H2A.xCricetulus griseus (Chinese hamster)Potency58.108225
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency2.187611
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency39.288126
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency79.432811
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency2.187612
Interferon betaHomo sapiens (human)Potency2.187611
interleukin 8Homo sapiens (human)Potency66.824211
lamin isoform A-delta10Homo sapiens (human)Potency0.501211
lethal factor (plasmid)Bacillus anthracis str. A2012Potency6.309611
mitogen-activated protein kinase 1Homo sapiens (human)Potency25.118911
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency38.763035
nuclear factor NF-kappa-B p105 subunit isoform 1Homo sapiens (human)Potency44.668411
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency50.226424
Nuclear receptor ROR-gammaHomo sapiens (human)Potency74.978011
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency12.960438
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency10.181511
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency56.015722
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency41.770033
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency20.811412
pregnane X nuclear receptorHomo sapiens (human)Potency27.193925
pregnane X receptorRattus norvegicus (Norway rat)Potency44.964712
progesterone receptorHomo sapiens (human)Potency42.476526
RAR-related orphan receptor gammaMus musculus (house mouse)Potency45.318125
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency65.468336
retinoid X nuclear receptor alphaHomo sapiens (human)Potency32.741746
SMAD family member 2Homo sapiens (human)Potency54.941011
SMAD family member 3Homo sapiens (human)Potency54.941011
TDP1 proteinHomo sapiens (human)Potency23.109311
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency23.974538
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.089111
thyroid stimulating hormone receptorHomo sapiens (human)Potency23.8002612
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency34.499826
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency39.810711
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency69.078211

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Androgen receptorRattus norvegicus (Norway rat)IC5018.197011