Page last updated: 2024-08-05 10:48:02

ethanolamines

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ChEBI ID: 23981

Members (22)

MemberDefinitionRole
2-diethylaminoethanolA member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.2-diethylaminoethanol
acebutololAn ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.acebutolol
als 8123A carboxylic acid that is 3-phenylpropanoic acid substituted at position 4 by a 2-hydroxy-3-(propan-2-ylamino)propoxy group.3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoic acid
atenololAn ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.atenolol
bitolterolThe di-4-toluate ester of (+-)-N-tert-butylnoradrenaline (colterol). A pro-drug for colterol, a beta2-adrenergic receptor agonist, bitolterol is used as its methanesulfonate salt for relief of bronchospasm in conditions such as asthma, chronic bronchitis and emphysema.bitolterol
clenbuterolA substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.clenbuterol
clorprenalineA member of the class of monochlorobenzenes that is chlorobenzene which is substituted by a 1-hydroxy-2-[(propan-2-yl)amino]ethyl group at position 2.1-(2-chlorophenyl)-2-isopropylaminoethanol
colterolA member of the class of ethanolamines that is catechol in which the hydrogen at position 4 is replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.colterol
deanolA tertiary amine that is ethanolamine having two N-methyl substituents.N,N-dimethylethanolamine
diethanolamineA member of the class of ethanolamines that is ethanolamine having a N-hydroxyethyl substituent.diethanolamine
dipivefrinThe dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.dipivefrin
esmololA methyl ester that is methyl 3-(4-hydroxyphenyl)propanoate in which the hydrogen attached to the phenolic hydroxy group is substituted by a 2-hydroxy-3-(isopropylamino)propyl group.methyl 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoate
ethambutolAn ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.ethambutol
ethanolamineA member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol.ethanolamine
mirabegronA monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome.mirabegron
n-methylaminoethanolAn ethanolamine compound having an N-methyl substituent.N-methylethanolamine
olomoucineA 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a cyclin-dependent kinase inhibitor.olomoucine
penbutololpenbutolol
practololN-(4-Hydroxyphenyl)acetamide in which the hydrogen of the phenolic hydroxy group is substituted by a 3-(isopropylaminoamino)-2-hydroxypropyl group. A selective beta blocker, it has been used in the emergency treatment of cardiac arrhythmias.practolol
sotalolA sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.sotalol
synephrineA phenethylamine alkaloid that is 4-(2-aminoethyl)phenol substituted by a hydroxy group at position 1 and a methyl group at the amino nitrogen.synephrine
tesA Good's buffer substance, pKa = 7.5 at 20 degreeC.N-tris(hydroxymethyl)methyl-2-aminoethanesulfonic acid; N-tris(hydroxymethyl)methyl-2-ammonioethanesulfonate

Research

Studies (18,872)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19907,301 (38.69)18.7374
1990's3,738 (19.81)18.2507
2000's3,472 (18.40)29.6817
2010's3,368 (17.85)24.3611
2020's993 (5.26)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials3,832 (18.38%)5.53%
Reviews1,139 (5.46%)6.00%
Case Studies1,785 (8.56%)4.05%
Observational64 (0.31%)0.25%
Other14,028 (67.29%)84.16%