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7-oxo steroid

Any oxo steroid carrying an oxo group at position 7.

ChEBI ID: 47789

Members (7)

MemberDefinitionRole
3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a hydroxy group at position 3, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic, anticholinergic and antiserotonergic activities.zhankuic acid B
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity.zhankuic acid C
4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity.zhankuic acid A
7-ketocholesterolA cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.7-ketocholesterol
7-ketodeoxycholic acid3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid
7-oxodehydroepiandrosteroneA 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7.7-ketodehydroepiandrosterone
dehydrocholic acidAn oxo-5beta-cholanic acid in which three oxo substituents are located at positions 3, 7 and 12 on the cholanic acid skeleton.3,7,12-trioxo-5beta-cholanic acid

Research

Studies (969)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990396 (40.87)18.7374
1990's103 (10.63)18.2507
2000's174 (17.96)29.6817
2010's236 (24.36)24.3611
2020's60 (6.19)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials35 (3.26%)5.53%
Reviews34 (3.17%)6.00%
Case Studies13 (1.21%)4.05%
Observational2 (0.19%)0.25%
Other989 (92.17%)84.16%