Page last updated: 2024-08-05 11:42:12
7-oxo steroid
Any oxo steroid carrying an oxo group at position 7.
ChEBI ID: 47789
Members (7)
| Member | Definition | Role |
|---|---|---|
| 3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a hydroxy group at position 3, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic, anticholinergic and antiserotonergic activities. | zhankuic acid B |
| 3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity. | zhankuic acid C |
| 4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity. | zhankuic acid A |
| 7-ketocholesterol | A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7. | 7-ketocholesterol |
| 7-ketodeoxycholic acid | 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid | |
| 7-oxodehydroepiandrosterone | A 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7. | 7-ketodehydroepiandrosterone |
| dehydrocholic acid | An oxo-5beta-cholanic acid in which three oxo substituents are located at positions 3, 7 and 12 on the cholanic acid skeleton. | 3,7,12-trioxo-5beta-cholanic acid |
Research
Studies (969)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 396 (40.87) | 18.7374 |
| 1990's | 103 (10.63) | 18.2507 |
| 2000's | 174 (17.96) | 29.6817 |
| 2010's | 236 (24.36) | 24.3611 |
| 2020's | 60 (6.19) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 35 (3.26%) | 5.53% |
| Reviews | 34 (3.17%) | 6.00% |
| Case Studies | 13 (1.21%) | 4.05% |
| Observational | 2 (0.19%) | 0.25% |
| Other | 989 (92.17%) | 84.16% |