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ChEBI ID: 26089
| Member | Definition | Class |
|---|---|---|
| diuron | A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group. | diuron |
| fenuron | A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of weeds in beetroot as well as various vegetable and ornamental crops. | fenuron |
| fluometuron | A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-(trifluoromethyl)phenyl group while the other is substituted by two methyl groups. It is a herbicide used for the control of broadleaf weeds and annual grasses in cotton. | fluometuron |
| methoxuron | A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which one of the nitrogens is substituted by a 3-chloro-4-methoxyphenyl group while the other is substituted by two methyl groups. It is a plant growth regulator and a pre- and post-emergence herbicide used for the control of grasses and broad-leaved weeds in carrots and cereals (e.g. wheat, barley and rye). | metoxuron |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 504 (33.25) | 18.7374 |
| 1990's | 125 (8.25) | 18.2507 |
| 2000's | 376 (24.80) | 29.6817 |
| 2010's | 406 (26.78) | 24.3611 |
| 2020's | 105 (6.93) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (0.06%) | 5.53% |
| Reviews | 13 (0.81%) | 6.00% |
| Case Studies | 2 (0.13%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,580 (99.00%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| AR protein | Homo sapiens (human) | Potency | 28.2571 | 6 | 10 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 41.1688 | 3 | 7 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0100 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 25.7877 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 38.4531 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 0.2239 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 44.5352 | 5 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 68.3804 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 54.1734 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0100 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0100 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 68.5896 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 36.9391 | 3 | 11 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 54.7509 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 60.9441 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.0041 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 24.3547 | 2 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 4.1095 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.3060 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 76.7241 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Photosystem II protein D1 | Spinacia oleracea (spinach) | IC50 | 1.0849 | 2 | 2 |