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rotenones
Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton and its substituted products.
ChEBI ID: 72581
Members (6)
| Member | Definition | Role |
|---|---|---|
| (6aS,12aS)-9-hydroxy-2,3-dimethoxy-8-(3-methylbut-2-enyl)-6a,12a-dihydro-6H-[1]benzopyrano[3,4-b][1]benzopyran-12-one | (6aS,12aS)-9-hydroxy-2,3-dimethoxy-8-(3-methylbut-2-enyl)-6a,12a-dihydro-6H-[1]benzopyrano[3,4-b][1]benzopyran-12-one | |
| amorphigenin | Amorphigenin | |
| deguelin | A rotenone that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted by methoxy groups at positions 9 and 10, and by two methyl groups at position 3 (the 7aS,13aS-stereoisomer). It exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants and reported to exert anti-tumour effects in various cancers. | deguelin |
| Dehydrodeguelin,7a,13a-Didehydrodeguelin | Dehydrodeguelin,7a,13a-Didehydrodeguelin | |
| rotenone | A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica). | rotenone |
| tephrosin | A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a and methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities. | tephrosin |
Research
Studies (4,293)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,174 (27.35) | 18.7374 |
| 1990's | 414 (9.64) | 18.2507 |
| 2000's | 930 (21.66) | 29.6817 |
| 2010's | 1,267 (29.51) | 24.3611 |
| 2020's | 508 (11.83) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 6 (0.13%) | 5.53% |
| Reviews | 94 (2.03%) | 6.00% |
| Case Studies | 13 (0.28%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4,525 (97.56%) | 84.16% |