A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
| Member | Definition | Class |
|---|
| 1,25-dihydroxyergocalciferol | A hydroxycalciol that is vitamin D2 bearing additional hydroxy substituents at positions 1alpha and 25. | 1alpha,25-dihydroxyvitamin D2 |
| 25-hydroxyvitamin d 2 | A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group. | 25-hydroxyvitamin D2 |
| 7-oxodehydroepiandrosterone | A 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7. | 7-ketodehydroepiandrosterone |
| 8,11,14-eicosatrienoic acid | An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14. | all-cis-icosa-8,11,14-trienoic acid |
| adenosine monophosphate | A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. | adenosine 5'-monophosphate |
| alpha-linolenic acid | A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect. | alpha-linolenic acid |
| arginine | An L-alpha-amino acid that is the L-isomer of arginine. | L-arginine |
| asparagine | An optically active form of asparagine having L-configuration. | L-asparagine zwitterion; L-asparagine |
| aspartame | A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. | aspartame zwitterion; aspartame |
| benphothiamine | A thioester that is a synthetic analogue of thiamine obtained by acylative cleavage of the thiazole ring and O-phospohorylation. | benfotiamine |
| berlition | The (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. | (R)-lipoic acid |
| biotin | An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. | biotin |
| calcifediol | A hydroxycalciol that is calciol in which the hydrogen at position 25 has been replaced by a hydroxy group. A prehormone resulting from the oxidation of calciol in the liver, it is further hydroxylated in the kidney to give calcitriol, the active form of vitamin D3. | calcidiol |
| calcitriol | A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol. | calcitriol |
| calcium citrate | An organic calcium salt composed of calcium cations and citrate anions in a 3:2 ratio. | calcium citrate |
| calcium gluconate | The calcium salt of D-gluconic acid. | calcium gluconate |
| chromium tripicolinate | | tris(picolinato)chromium |
| citrulline | The L-enantiomer of citrulline. | L-citrulline zwitterion; L-citrulline |
| creatine | A glycine derivative having methyl and amidino groups attached to the nitrogen. | creatine zwitterion; creatine |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| d-alpha tocopherol | An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. | (R,R,R)-alpha-tocopherol |
| docosahexaenoate | A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19. | all-cis-docosa-4,7,10,13,16,19-hexaenoic acid |
| eicosapentaenoic acid | An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. | all-cis-5,8,11,14,17-icosapentaenoic acid |
| ferric citrate | An iron chelate resulting from the combination of iron(3+) and citrate(3-). | iron(III) citrate |
| glutamic acid | An optically active form of glutamic acid having L-configuration. | L-glutamic acid |
| glutamine | An optically active form of glutamine having L-configuration. | L-glutamine zwitterion; L-glutamine |
| glycine | The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. | glycine zwitterion; glycine |
| glycocyamine | The N-amidino derivative of glycine. | guanidinoacetic acid zwitterion; guanidinoacetic acid |
| histidine | The L-enantiomer of the amino acid histidine. | L-histidine zwitterion; L-histidine |
| levocarnitine | The (R)-enantiomer of carnitine. | (R)-carnitine |
| lysine | An L-alpha-amino acid; the L-isomer of lysine. | L-Lysine zwitterion; L-lysine |
| manganese chloride | A hydrate that is the tetrahydrate form of manganese(II) chloride. | manganese(II) chloride tetrahydrate |
| methionine | The L-enantiomer of methionine. | L-methionine zwitterion; L-methionine |
| n-acetylaspartic acid | An N-acyl-L-aspartic acid in which the acyl group is specified as acetyl. | N-acetyl-L-aspartic acid |
| n-acetylmethionine | An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. | N-acetyl-L-methionine |
| oleuropein | A secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars. | oleuropein |
| pantethine | An organic disulfide that consists of two molecules of pantothenic acid linked by amide bonds to a cysteamine disulfide bridging group. | pantethine |
| phenylalanine | The L-enantiomer of phenylalanine. | L-phenylalanine zwitterion; L-phenylalanine |
| proline | Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. | L-proline zwitterion; L-proline |
| s-adenosylmethionine | A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine |
| sodium selenite | An inorganic sodium salt composed of sodium and selenite ions in a 2:1 ratio. | disodium selenite |
| succinic acid | An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. | succinic acid |
| threonine | An optically active form of threonine having L-configuration. | L-threonine zwitterion; L-threonine |
| tryptophan | The L-enantiomer of tryptophan. | L-tryptophan zwitterion; L-tryptophan |
| tyrosine | An optically active form of tyrosine having L-configuration. | L-tyrosine zwitterion; L-tyrosine |
| valine | The L-enantiomer of valine. | L-valine zwitterion; L-valine |
| vitamin d 2 | A vitamin D supplement and has been isolated from alfalfa. | vitamin D2 |
| vitamin k 3 | A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia. | menadione |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 30.0229 | 1 | 5 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 17.0937 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 0.3162 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 51.0944 | 4 | 5 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 40.3535 | 2 | 8 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 21.8820 | 1 | 12 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 18.8541 | 1 | 2 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 3.6978 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 22.8348 | 9 | 43 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 25.7446 | 3 | 16 |
| arylsulfatase A | Homo sapiens (human) | Potency | 6.9252 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 21.3180 | 3 | 4 |
| Ataxin-2 | Homo sapiens (human) | Potency | 33.8168 | 1 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 14.6718 | 2 | 6 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 41.3244 | 2 | 5 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 21.7154 | 2 | 8 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 33.3098 | 1 | 3 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 52.2158 | 1 | 2 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 52.2158 | 1 | 2 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.1060 | 3 | 17 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 25.4659 | 2 | 5 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 30.6345 | 1 | 4 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 20.7945 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 15.5796 | 2 | 7 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 23.2863 | 1 | 3 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 8.5398 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 16.0644 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.1989 | 1 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 15.1978 | 2 | 7 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 6.4856 | 2 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 22.8147 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 16.0644 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 6.2560 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 15.4871 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 16.9784 | 2 | 10 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.9046 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 34.9936 | 1 | 6 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 26.1464 | 2 | 5 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 30.3134 | 2 | 4 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 26.6169 | 2 | 7 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 33.6254 | 2 | 9 |
| endonuclease IV | Escherichia coli | Potency | 0.8913 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 35.2510 | 11 | 46 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 32.0049 | 2 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 22.1769 | 7 | 27 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 15.5322 | 1 | 22 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 28.3491 | 4 | 8 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 45.6031 | 4 | 11 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 22.9214 | 1 | 6 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 6.3096 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 38.9018 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 16.9784 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 15.7168 | 2 | 16 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 23.2243 | 3 | 13 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 9.2000 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 19.7568 | 2 | 10 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 32.4648 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 37.0641 | 5 | 13 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 45.9719 | 1 | 3 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 18.4697 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 29.4822 | 2 | 9 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 26.2000 | 1 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 8.7725 | 2 | 9 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 24.9054 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 24.3365 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 50.0541 | 2 | 5 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 41.8736 | 1 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 38.3186 | 2 | 7 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 10.4961 | 2 | 6 |
| IDH1 | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 44.6701 | 2 | 4 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 38.9018 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 13.5836 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 24.9765 | 1 | 3 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 24.9765 | 1 | 3 |
| Interferon beta | Homo sapiens (human) | Potency | 30.9338 | 2 | 7 |
| interleukin 8 | Homo sapiens (human) | Potency | 84.1267 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 17.8146 | 3 | 12 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 6.4140 | 1 | 4 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 39.8445 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 50.6583 | 3 | 3 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 25.4565 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 19.4899 | 2 | 17 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 24.8366 | 2 | 5 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.3981 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 26.9680 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 56.2341 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 56.2341 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.2512 | 2 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 29.3620 | 4 | 14 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 2.5929 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 26.3962 | 2 | 6 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 16.5545 | 2 | 19 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 36.6743 | 3 | 10 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 25.9206 | 2 | 4 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 13.6819 | 2 | 6 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 67.8835 | 1 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 27.3007 | 5 | 21 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 31.7303 | 5 | 14 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 62.1486 | 1 | 13 |
| PINK1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 3.9811 | 1 | 1 |
| polyprotein | Zika virus | Potency | 25.1189 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 10.0040 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 9.8843 | 1 | 4 |
| PPM1D protein | Homo sapiens (human) | Potency | 29.6058 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 46.1731 | 2 | 5 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 79.4328 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 40.7437 | 2 | 5 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 22.0164 | 2 | 4 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 12.6914 | 2 | 3 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 19.0819 | 2 | 11 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 4.2336 | 1 | 7 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 36.5684 | 3 | 15 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 21.3645 | 4 | 12 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 16.8336 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 42.0493 | 2 | 7 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 42.0493 | 2 | 7 |
| Smad3 | Homo sapiens (human) | Potency | 31.1166 | 1 | 3 |
| snurportin-1 | Homo sapiens (human) | Potency | 44.6701 | 2 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 1.5849 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 19.1498 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 20.0000 | 2 | 26 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 32.4570 | 1 | 7 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 32.0840 | 2 | 10 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 33.6650 | 2 | 17 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 31.4603 | 4 | 5 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 22.7637 | 6 | 14 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 27.7247 | 1 | 1 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 22.0164 | 1 | 2 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 3.9811 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 3.9811 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 35.1471 | 2 | 13 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 21.7557 | 2 | 11 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 32.0340 | 5 | 12 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 36.9525 | 1 | 12 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 45.9719 | 1 | 3 |
| WRN | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 9.1905 | 2 | 4 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 14.4167 | 2 | 6 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 22.7667 | 1 | 3 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 1.7300 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 6,300.0000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Homo sapiens (human) | Ki | 19.2000 | 1 | 1 |
| 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 40.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | IC50 | 80.2000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 3 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 14.4167 | 2 | 6 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 22.7667 | 1 | 3 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 132.1300 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 501.2502 | 4 | 4 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 80.0000 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Ki | 580.0000 | 1 | 1 |
| Alcohol dehydrogenase E chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Alcohol dehydrogenase S chain | Equus caballus (horse) | Ki | 38.0000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.2000 | 1 | 1 |
| Aldehyde oxidase 1 | Macaca fascicularis (crab-eating macaque) | IC50 | 0.1100 | 1 | 1 |
| Aldehyde oxidase 1 | Mus musculus (house mouse) | IC50 | 0.1500 | 1 | 1 |
| Aldehyde oxidase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 2.0000 | 1 | 1 |
| Aldehyde oxidase 1 | Cavia porcellus (domestic guinea pig) | Ki | 7.2300 | 1 | 1 |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.1900 | 1 | 1 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 77.5250 | 3 | 4 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Bos taurus (cattle) | IC50 | 80.2033 | 3 | 3 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.4000 | 1 | 1 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 59.0067 | 3 | 3 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 4.7440 | 4 | 5 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 13.3550 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 2.5733 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.4400 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 10.9500 | 2 | 2 |
| Amino acid transporter | Rattus norvegicus (Norway rat) | IC50 | 1,486.1222 | 6 | 9 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 15.5000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 15.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.8541 | 30 | 30 |
| Androgen receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Angiotensin-converting enzyme | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 43.5333 | 1 | 3 |
| Asc-type amino acid transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 300.0000 | 1 | 1 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 7.7510 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 343.0000 | 1 | 1 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | Escherichia coli K-12 | Ki | 38,000.0000 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 528.8750 | 2 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 1.6300 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Carnitine O-palmitoyltransferase 1, muscle isoform | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 6.7600 | 1 | 1 |
| Cationic amino acid transporter 3 | Homo sapiens (human) | IC50 | 220.5000 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 2.3600 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Chain A, ADP-dependent glucokinase | Pyrococcus furiosus | Ki | 60.0000 | 1 | 1 |
| Chain A, AMINOPEPTIDASE | Streptomyces griseus | Ki | 11,366.6667 | 1 | 3 |
| Chain A, Arginase 1 | Rattus norvegicus (Norway rat) | Ki | 3,600.0000 | 1 | 1 |
| Chain A, CHORISMATE MUTASE | Saccharomyces cerevisiae (brewer's yeast) | Ki | 50.0000 | 1 | 1 |
| Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | Escherichia coli | Ki | 15.0000 | 1 | 1 |
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 2 |
| Chain A, Methionine aminopeptidase | Pyrococcus furiosus | Ki | 150,000.0000 | 1 | 1 |
| Chain A, phosphodiesterase-nucleotide pyrophosphatase | Xanthomonas citri pv. citri str. 306 | Ki | 260.0000 | 1 | 1 |
| Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta)) | Homo sapiens (human) | IC50 | 4.0000 | 1 | 1 |
| Chain A, Ribonuclease pancreatic | Bos taurus (cattle) | Ki | 46.0000 | 1 | 2 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | Pisum sativum (garden pea) | Ki | 36,600.0000 | 1 | 2 |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | IC50 | 0.8210 | 1 | 1 |
| Choline O-acetyltransferase | Homo sapiens (human) | IC50 | 1,800,000,000.0000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 300.0000 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 668.3333 | 3 | 3 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 53.2500 | 1 | 4 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 25.0000 | 4 | 4 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 7.7500 | 1 | 1 |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | IC50 | 15.3000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 6.9620 | 1 | 2 |
| Cytochrome P450 2C19 | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 1.3046 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 0.0093 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.0001 | 1 | 1 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 1.0700 | 2 | 2 |
| Delta-aminolevulinic acid dehydratase | Escherichia coli K-12 | Ki | 12,500.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 6,500.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 2,800.0000 | 1 | 1 |
| DNA gyrase subunit A | Mycobacterium tuberculosis H37Rv | IC50 | 200.0000 | 2 | 2 |
| DNA gyrase subunit B | Mycobacterium tuberculosis H37Rv | IC50 | 200.0000 | 1 | 1 |
| Dual specificity protein phosphatase 1 | Mus musculus (house mouse) | IC50 | 24.0000 | 1 | 1 |
| Dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 20.5000 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 80.2000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | IC50 | 3,362.7667 | 3 | 3 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | IC50 | 76.4503 | 4 | 6 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Ki | 33.3114 | 1 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | IC50 | 65.9784 | 2 | 4 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Ki | 62.5478 | 1 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | IC50 | 41.1195 | 2 | 4 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Ki | 25.0848 | 1 | 2 |
| Excitatory amino acid transporter 4 | Rattus norvegicus (Norway rat) | IC50 | 12.6930 | 2 | 4 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 150,000.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 0.3900 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.6436 | 11 | 11 |
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | IC50 | 1.3000 | 2 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | IC50 | 428.0000 | 2 | 2 |
| Glutamate receptor 1 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 1.3607 | 3 | 3 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.6345 | 2 | 2 |
| Glutamate receptor 2 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 0.9400 | 3 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Ki | 0.4452 | 4 | 5 |
| Glutamate receptor 3 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Ki | 2.3122 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | IC50 | 0.6130 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 0.5885 | 4 | 4 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 0.8680 | 3 | 3 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.7270 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | Ki | 0.7010 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Ki | 0.1284 | 5 | 7 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | Ki | 1.1060 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Ki | 0.9566 | 7 | 9 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | Ki | 0.7890 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 0.4201 | 4 | 6 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 0.3800 | 3 | 5 |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | Ki | 0.7337 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 42.2039 | 9 | 10 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 0.0700 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 0.2270 | 7 | 7 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 7.3057 | 6 | 7 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 4,400.0000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 57.4500 | 1 | 2 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 31.3750 | 3 | 4 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 34.7500 | 2 | 2 |
| Glycine--tRNA ligase | Bombyx mori (domestic silkworm) | Ki | 80.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 17.9500 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 0.0660 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5880 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 2 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 21.9167 | 6 | 6 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 50.7900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 97.6700 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 64.9800 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| hypothetical protein SA1422 | Staphylococcus aureus subsp. aureus N315 | IC50 | 42.9000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 100.4540 | 5 | 5 |
| Inosine-5'-monophosphate dehydrogenase | Escherichia coli K-12 | Ki | 450.0000 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 18.7000 | 1 | 1 |
| Intestinal-type alkaline phosphatase | Bos taurus (cattle) | IC50 | 80.2060 | 5 | 5 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 47.5500 | 3 | 4 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 0.0050 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 115.8182 | 3 | 11 |
| Large neutral amino acids transporter small subunit 1 | Rattus norvegicus (Norway rat) | Ki | 55.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 710.0000 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 9.6000 | 1 | 1 |
| M-phase inducer phosphatase 1 | Homo sapiens (human) | IC50 | 4.5500 | 2 | 2 |
| M-phase inducer phosphatase 2 | Homo sapiens (human) | IC50 | 3.1600 | 3 | 3 |
| M-phase inducer phosphatase 3 | Homo sapiens (human) | IC50 | 18.9000 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 3.6067 | 3 | 3 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | Ki | 0.3400 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 7.6500 | 4 | 4 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Ki | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 5.6000 | 4 | 4 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 4.3167 | 3 | 3 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Ki | 38.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Ki | 5,400.0000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | IC50 | 0.0057 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | Ki | 9.5000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | Ki | 3.4000 | 2 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 54.8750 | 4 | 4 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 2.2500 | 1 | 1 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | Homo sapiens (human) | Ki | 5,000.0000 | 1 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 24.2000 | 1 | 1 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | Mus musculus (house mouse) | IC50 | 2.2000 | 1 | 1 |
| Neutral amino acid transporter A | Homo sapiens (human) | IC50 | 2,056.0000 | 1 | 3 |
| Neutral amino acid transporter B(0) | Homo sapiens (human) | IC50 | 3,738.3333 | 1 | 3 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Ki | 2,350.0000 | 1 | 2 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 0.2000 | 1 | 1 |
| Oxoeicosanoid receptor 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 3 |
| perilipin-1 | Homo sapiens (human) | IC50 | 8.5310 | 1 | 2 |
| perilipin-5 | Homo sapiens (human) | IC50 | 9.8500 | 1 | 2 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| phospholipase A2 precursor | Homo sapiens (human) | IC50 | 22.3000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 1,000.0000 | 1 | 2 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 1.8000 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 63.8350 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 4.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 40.3333 | 1 | 3 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 63.8350 | 1 | 2 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 9.6333 | 1 | 3 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.0002 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Protein-glutamine gamma-glutamyltransferase 2 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 2,850.0000 | 1 | 4 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Receptor protein-tyrosine kinase | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase eta | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 23.8200 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 23.8200 | 1 | 3 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 6.9620 | 1 | 2 |
| S-ribosylhomocysteine lyase | Bacillus subtilis subsp. subtilis str. 168 | Ki | 61.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 3.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | Ki | 8.6000 | 1 | 1 |
| Serine racemase | Homo sapiens (human) | Ki | 366.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 2,238.7200 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 1,348.9600 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 68.8000 | 2 | 2 |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Solute carrier family 13 member 3 | Homo sapiens (human) | IC50 | 107.0000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 27,542.3000 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 837.2547 | 3 | 3 |
| Sortase A | Streptococcus mutans | IC50 | 10.2000 | 1 | 1 |
| Sterol regulatory element-binding protein 1 | Homo sapiens (human) | IC50 | 1.1760 | 1 | 1 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 500.0000 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | IC50 | 19.9526 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 50.3333 | 1 | 3 |
| Tissue factor | Homo sapiens (human) | IC50 | 42.6026 | 2 | 5 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 8.3620 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 19.7000 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 70.0000 | 2 | 2 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 0.0001 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | IC50 | 55.0000 | 2 | 2 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 3 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Ki | 11,500.0000 | 1 | 1 |
| Tubulin--tyrosine ligase | Homo sapiens (human) | Ki | 25.0000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | Homo sapiens (human) | IC50 | 290.0000 | 1 | 1 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 | Mus musculus (house mouse) | IC50 | 180.5000 | 1 | 2 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L3 | Homo sapiens (human) | IC50 | 71.0000 | 2 | 2 |
| Ubiquitin carboxyl-terminal hydrolase isozyme L3 | Mus musculus (house mouse) | IC50 | 180.5000 | 1 | 2 |
| Uracil nucleotide/cysteinyl leukotriene receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Vitamin D3 receptor | Bos taurus (cattle) | IC50 | 0.0000 | 1 | 1 |
| Vitamin D3 receptor | Homo sapiens (human) | IC50 | 0.3401 | 19 | 19 |
| Vitamin D3 receptor | Rattus norvegicus (Norway rat) | Ki | 0.0001 | 11 | 11 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Mus musculus (house mouse) | Ki | 0.9786 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | Homo sapiens (human) | EC50 | 0.0030 | 1 | 1 |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Burkholderia pseudomallei K96243 | Kd | 1,000.0000 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Kd | 5,000.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | EC50 | 3.7095 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | EC50 | 3.6500 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | EC50 | 2.9397 | 3 | 3 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 3.7000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | EC50 | 5.9000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | EC50 | 0.5000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Kd | 3.5000 | 4 | 4 |
| Alpha-tocopherol transfer protein | Homo sapiens (human) | Kd | 2.4200 | 1 | 1 |
| Chain A, Aspartate Aminotransferase | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, Avidin | Gallus gallus (chicken) | Kd | 0.3000 | 1 | 2 |
| Chain A, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain A, FATTY ACID-BINDING PROTEIN, BRAIN | Homo sapiens (human) | Kd | 0.0534 | 1 | 2 |
| Chain A, Glutamine Binding Protein | Escherichia coli | Kd | 0.5000 | 1 | 1 |
| Chain A, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 101.8000 | 1 | 5 |
| Chain A, HISTIDINE-BINDING PROTEIN | Escherichia coli | Kd | 0.0640 | 1 | 1 |
| Chain A, Methionyl-tRNA synthetase | Escherichia coli | Kd | 11.0000 | 1 | 2 |
| Chain A, Protein (aspartate Aminotransferase) | Escherichia coli | Kd | 2,400.0000 | 1 | 1 |
| Chain A, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain A, Slr1257 protein | Synechocystis sp. PCC 6803 substr. Kazusa | Kd | 0.2400 | 1 | 1 |
| Chain A, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 13 |
| Chain A, Streptavidin Complex With Biotin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Chain A, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Chain A, TYROSYL-tRNA SYNTHETASE | Geobacillus stearothermophilus | Kd | 11.6000 | 1 | 1 |
| Chain A, Vitamin D Nuclear Receptor | Homo sapiens (human) | Kd | 0.0006 | 1 | 1 |
| Chain B, GLYCOGEN PHOSPHORYLASE B | Oryctolagus cuniculus (rabbit) | Kd | 85.3333 | 1 | 3 |
| Chain B, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain B, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 4 |
| Chain B, tryptophanyl-tRNA synthetase | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain C, Tryptophanyl-tRNA synthetase II | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain D, Circularly Permuted Core-streptavidin E51/a46 | Streptomyces avidinii | Kd | 0.0439 | 1 | 1 |
| Chain D, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain D, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 9 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | Salmonella enterica subsp. enterica serovar Typhimurium | Kd | 0.2570 | 1 | 6 |
| Chain K, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | Kd | 100.0000 | 2 | 2 |
| Free fatty acid receptor 1 | Homo sapiens (human) | EC50 | 10.4338 | 6 | 7 |
| Free fatty acid receptor 4 | Homo sapiens (human) | EC50 | 2.9180 | 2 | 2 |
| Glutamate receptor 1 | Homo sapiens (human) | EC50 | 792,445,056.0762 | 12 | 20 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 27.3799 | 6 | 7 |
| Glutamate receptor 2 | Homo sapiens (human) | EC50 | 722,116,393.1444 | 8 | 11 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 1,482,620,106.9400 | 4 | 5 |
| Glutamate receptor 3 | Homo sapiens (human) | EC50 | 2,264,128,594.8718 | 5 | 7 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 54.8048 | 5 | 6 |
| Glutamate receptor 4 | Homo sapiens (human) | EC50 | 9,952,675,009.4244 | 2 | 4 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 18.6392 | 4 | 5 |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | EC50 | 57.3333 | 3 | 3 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | EC50 | 129.1633 | 2 | 3 |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | EC50 | 25.0000 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | EC50 | 65.9615 | 2 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 0.8959 | 12 | 13 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 1.1223 | 6 | 7 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | EC50 | 0.4856 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | EC50 | 0.3196 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | EC50 | 0.1858 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | EC50 | 0.1293 | 3 | 3 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 94.7496 | 1 | 2 |
| Histidine-binding periplasmic protein | Escherichia coli K-12 | Kd | 0.1140 | 1 | 1 |
| insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 2.4495 | 2 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.0000 | 1 | 1 |
| L-lactate dehydrogenase A chain | Homo sapiens (human) | Kd | 650.0000 | 1 | 1 |
| Lymphocyte antigen 96 | Homo sapiens (human) | Kd | 379.0000 | 1 | 1 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | EC50 | 45.2375 | 4 | 4 |
| Metabotropic glutamate receptor 1 | Rattus norvegicus (Norway rat) | EC50 | 13.1512 | 10 | 12 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 7.3849 | 12 | 13 |
| Metabotropic glutamate receptor 2 | Rattus norvegicus (Norway rat) | EC50 | 8.7450 | 8 | 10 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | EC50 | 2.8572 | 5 | 5 |
| Metabotropic glutamate receptor 3 | Rattus norvegicus (Norway rat) | EC50 | 1.6294 | 3 | 4 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 14.9333 | 3 | 3 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 6.3776 | 8 | 10 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | EC50 | 163.5500 | 4 | 4 |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | EC50 | 6.4817 | 8 | 10 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | EC50 | 98.3000 | 3 | 3 |
| Metabotropic glutamate receptor 6 | Rattus norvegicus (Norway rat) | EC50 | 35.7000 | 5 | 5 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | EC50 | 625.2950 | 4 | 4 |
| Metabotropic glutamate receptor 7 | Rattus norvegicus (Norway rat) | EC50 | 800.0000 | 2 | 3 |
| Metabotropic glutamate receptor 8 | Mus musculus (house mouse) | EC50 | 0.0220 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Rattus norvegicus (Norway rat) | EC50 | 14.4933 | 3 | 3 |
| Methyl-accepting chemotaxis protein NahY | Pseudomonas putida | Kd | 82.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 245.0000 | 2 | 2 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Kd | 7.0000 | 2 | 2 |
| Nuclear factor erythroid 2-related factor 2 | Homo sapiens (human) | EC50 | 21.0000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 1.7673 | 2 | 3 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0580 | 1 | 1 |
| P2Y purinoceptor 1 | Homo sapiens (human) | EC50 | 4.3500 | 1 | 2 |
| P2Y purinoceptor 1 | Meleagris gallopavo (turkey) | EC50 | 3.1500 | 1 | 2 |
| P2Y purinoceptor 11 | Homo sapiens (human) | EC50 | 17.2500 | 1 | 1 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 1.8925 | 1 | 2 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Kd | 2.0000 | 1 | 2 |
| Protease | Human immunodeficiency virus 1 | Kd | 0.0011 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | EC50 | 7.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 10.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 10.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | EC50 | 0.0016 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | Kd | 64.3000 | 1 | 1 |
| Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Vitamin D-binding protein | Homo sapiens (human) | Kd | 0.0240 | 1 | 1 |
| Vitamin D3 receptor | Bos taurus (cattle) | EC50 | 0.0001 | 2 | 2 |
| Vitamin D3 receptor | Homo sapiens (human) | EC50 | 0.0394 | 36 | 36 |
| Vitamin D3 receptor | Mus musculus (house mouse) | EC50 | 0.3500 | 1 | 2 |
| Vitamin D3 receptor | Rattus norvegicus (Norway rat) | EC50 | 0.0002 | 7 | 7 |
| Vitamin D3 receptor | Homo sapiens (human) | Kd | 0.0001 | 1 | 1 |
| Vitamin D3 receptor | Sus scrofa (pig) | Kd | 0.0001 | 1 | 1 |
| Vitamin D3 receptor A | Danio rerio (zebrafish) | EC50 | 0.0055 | 1 | 1 |
| Vitamin D3 receptor A | Danio rerio (zebrafish) | Kd | 1.2000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial | Mus musculus (house mouse) | Km | 0.4800 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 113.0000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | Km | 14.0000 | 1 | 1 |
| Adenosine deaminase-like protein | Homo sapiens (human) | Km | 32.8000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 3.6413 | 1 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 3.6413 | 1 | 6 |
| Adenylate cyclase type 5 | Homo sapiens (human) | Km | 15.6000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Km | 380.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Adenylate kinase isoenzyme 1 | Homo sapiens (human) | Km | 175.0000 | 1 | 1 |
| Adenylate kinase isoenzyme 1 | Rattus norvegicus (Norway rat) | Km | 580.0000 | 1 | 1 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | Km | 441.0000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | DC50 | 0.7550 | 2 | 2 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 26.2250 | 1 | 4 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 49.5000 | 1 | 4 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 41.6000 | 1 | 4 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 86.0000 | 2 | 8 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 36.8250 | 1 | 4 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 23.3500 | 1 | 4 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Activity | 0.0300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 11.5713 | 17 | 53 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ka | 22.2971 | 3 | 7 |
| Carbonic anhydrase 13 | Homo sapiens (human) | KA | 0.5650 | 1 | 2 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 8.2875 | 2 | 4 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 8.0829 | 3 | 7 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 21.9750 | 1 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Activity | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ka | 18.0170 | 20 | 62 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ka | 31.0364 | 4 | 11 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 39.0000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ka | 25.3462 | 5 | 13 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 3.8514 | 3 | 7 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 3.4591 | 3 | 7 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 14.1483 | 4 | 12 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 22.5100 | 3 | 7 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 20.1525 | 4 | 8 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 33.3871 | 1 | 7 |
| Carnitine O-acetyltransferase | Homo sapiens (human) | Km | 300.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | ED50 | 0.0002 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | ED50 | 0.0002 | 1 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Activity | 25.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | ED50 | 0.0002 | 1 | 1 |
| Dihydrolipoyl dehydrogenase, mitochondrial | Sus scrofa (pig) | Km | 72.0000 | 1 | 1 |
| EWS/FLI fusion protein | Homo sapiens (human) | AbsAC35_uM | 40.2500 | 1 | 1 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | Km | 8.5500 | 2 | 2 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | Km | 21.0000 | 2 | 2 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | Km | 17.4500 | 2 | 2 |
| Excitatory amino acid transporter 3 | Rattus norvegicus (Norway rat) | Ks | 5.1000 | 1 | 1 |
| General amino-acid permease GAP1 | Saccharomyces cerevisiae S288C | Km | 37.0000 | 1 | 1 |
| Glutamate 5-kinase | Escherichia coli K-12 | I0.5 | 2.5000 | 1 | 1 |
| Glutamate racemase | Enterococcus faecalis V583 | Km | 1,200.0000 | 1 | 1 |
| Glutamate racemase | Helicobacter pylori 26695 | Km | 5,176.6667 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 22.4125 | 1 | 4 |
| Glutathione reductase | Plasmodium falciparum 3D7 | Km | 82.2000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Km | 31.2000 | 1 | 1 |
| GTP:AMP phosphotransferase AK3, mitochondrial | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Km | 15.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | Km | 12.6000 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Activity | 1.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Activity | 9.0000 | 1 | 1 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Activity | 12.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Activity | 4.0000 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Activity | 20.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Activity | 5,400.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | DC50 | 200.0000 | 1 | 1 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 4,443.3333 | 1 | 3 |
| NAD | Homo sapiens (human) | Km | 1.3000 | 3 | 3 |
| NAD | Homo sapiens (human) | Vmax | 7,286.0000 | 1 | 1 |
| NADP-dependent malic enzyme, mitochondrial | Homo sapiens (human) | Activity | 2,100.0000 | 1 | 1 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Activity | 14.5000 | 1 | 1 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Km | 2.7000 | 1 | 1 |
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | Activity | 25.0000 | 1 | 1 |
| Nitric oxide synthase, endothelial | Bos taurus (cattle) | Km | 1.1000 | 1 | 1 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Activity | 14.0000 | 1 | 1 |
| Nitric oxide synthase, inducible | Homo sapiens (human) | Km | 5.7000 | 2 | 2 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | Km | 9.5000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 3.0885 | 1 | 4 |
| Platelet-activating factor acetylhydrolase | Homo sapiens (human) | Km | 72.0000 | 1 | 5 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 230.0000 | 2 | 2 |
| Receptor-type tyrosine-protein phosphatase beta | Homo sapiens (human) | Kis | 2,330.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | ED50 | 50.0000 | 1 | 1 |
| S-adenosylmethionine synthase isoform type-1 | Rattus norvegicus (Norway rat) | Km | 42.8000 | 2 | 2 |
| S-adenosylmethionine synthase isoform type-2 | Rattus norvegicus (Norway rat) | Km | 10.3000 | 2 | 2 |
| SLC16A10 protein | Homo sapiens (human) | Km | 609.6667 | 1 | 3 |
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | Km | 0.0619 | 1 | 1 |
| Taste receptor type 2 member 14 | Homo sapiens (human) | Activity | 1,000.0000 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | Km | 21.0000 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | x fold | 375.0000 | 1 | 1 |
| Tryprostatin B synthase | Aspergillus fumigatus Af293 | Km | 820.0000 | 1 | 1 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Km | 167.0000 | 1 | 1 |
| Vitamin D3 receptor | Homo sapiens (human) | Activity | 1,254.0000 | 2 | 2 |
| Vitamin D3 receptor | Homo sapiens (human) | ED50 | 0.1007 | 4 | 4 |
| Vitamin D3 receptor | Rattus norvegicus (Norway rat) | ED50 | 500,000.0002 | 6 | 6 |