Any tetrahydropyrimidine in which the double bond is between positions 1 and 2.
ChEBI ID: 78715
Member | Definition | Role |
---|---|---|
ectoine | A carboxamidine heterocycle obtained by formal condensation of (2S)-2,4-diaminobutanoic acid with acetic acid. | ectoine zwitterion; ectoine |
pyrantel | A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'. | pyrantel |
pyrostatin a | A carboxamidine heterocycle which is obtained by formal condensation of 4-amino-L-allothreonine with acetic acid. | 5-hydroxyectoine zwitterion; 5-hydroxyectoine |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 167 (26.30) | 18.7374 |
1990's | 57 (8.98) | 18.2507 |
2000's | 133 (20.94) | 29.6817 |
2010's | 194 (30.55) | 24.3611 |
2020's | 84 (13.23) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 64 (8.32%) | 5.53% |
Reviews | 39 (5.07%) | 6.00% |
Case Studies | 8 (1.04%) | 4.05% |
Observational | 2 (0.26%) | 0.25% |
Other | 656 (85.31%) | 84.16% |