Page last updated: 2024-08-05 12:40:51

1,4,5,6-tetrahydropyrimidines

Any tetrahydropyrimidine in which the double bond is between positions 1 and 2.

ChEBI ID: 78715

Members (3)

MemberDefinitionRole
ectoineA carboxamidine heterocycle obtained by formal condensation of (2S)-2,4-diaminobutanoic acid with acetic acid.ectoine zwitterion; ectoine
pyrantelA carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.pyrantel
pyrostatin aA carboxamidine heterocycle which is obtained by formal condensation of 4-amino-L-allothreonine with acetic acid.5-hydroxyectoine zwitterion; 5-hydroxyectoine

Research

Studies (635)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990167 (26.30)18.7374
1990's57 (8.98)18.2507
2000's133 (20.94)29.6817
2010's194 (30.55)24.3611
2020's84 (13.23)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials64 (8.32%)5.53%
Reviews39 (5.07%)6.00%
Case Studies8 (1.04%)4.05%
Observational2 (0.26%)0.25%
Other656 (85.31%)84.16%