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L-arginine derivative

A proteinogenic amino acid derivative resulting from reaction of L-arginine at the amino group, the carboxy group, or the guanidyl group, or from the replacement of any hydrogen of L-arginine by a heteroatom.

ChEBI ID: 83965

Members (16)

MemberDefinitionRole
adp-ribosylarginineN(omega)-(ADP-D-ribosyl)-L-arginine
argininamideAn amino acid amide resulting from the formal condensation of the carboxy group of L-arginine with ammonia.L-arginine amide
arginine beta-naphthylamideAn L-arginine derivative that is the amide obtained by formal condensation of the carboxy group of L-arginine with the amino group of 2-naphthylamine.L-arginine 2-naphthylamide
argininehydroxamic acidAn arginine derivative obtained by formal condensation of the carboxy group of L-arginine with the amino group of hydroxylamine.L-arginine hydroxamate
argpyrimidineA member of the class of hydroxypyrimidines obtained by cyclocondensation of L-arginine and methylglyoxal; a methyl glyoxal-derived advanced glycation end-product (AGE) in familial amyloidotic polyneuropathy and human cancers.argpyrimidine
delta-n-methylarginineA non-proteinogenic L-alpha-amino acid that is L-arginine substituted by a methyl group at N(5)-position.N(5)-methyl-L-arginine
EG00229A member of the class of thiophenes that is thiophene substituted by a carbonyl-L-arginine and (2,1,3-benzothiadiazole-4-sulfonyl)amino groups at positions 2 and 3. It is an inhibitor of the neuropilin-1 and VEGF-A interaction and a potential anti-cancer agent.EG00229
l803087A fluoroindole that is 1H-indole substituted by phenyl, 4-{[(2S)-5-carbamimidamido-1-methoxy-1-oxopentan-2-yl]amino}-4-oxobutyl, fluoro and fluoro groups at positions 2, 3, 5 and 7, respectively. It is a selective nonpeptidic agonist of the somatostatin subtype-4 (SST4) receptor with Ki of 0.7 nM.L-803087
n,n-dimethylarginineA L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.N(omega),N(omega)-dimethyl-L-arginine
ng-nitroarginine methyl esterAn alpha-amino acid ester that is the methyl ester of N(gamma)-nitro-L-arginine.N(gamma)-nitro-L-arginine methyl ester
nitroarginineAn L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group.N(gamma)-nitro-L-arginine
nopalineAn amino acid opine resulting from the formal reductive condensation of the amino group of L-arginine with the keto group of 2-oxopentanedioic acid.D-nopaline
omega-n-methylarginineA L-arginine derivative with a N(omega)-methyl substituent.(2S)-2-amino-5-[[amino(methylimino)methyl]amino]pentanoic acid; N(omega)-methyl-L-arginine zwitterion; N(omega)-methyl-L-arginine
phospho-l-arginineAn arginine derivative that is L-arginine substituted by a phosphono group at N(omega)-position.N(omega)-phospho-L-arginine
s-methylthiocitrullineAn L-arginine derivative in which the guanidino NH2 group of L-arginine is replaced by a methylsufanyl group.S-methyl-L-thiocitrulline
symmetric dimethylarginineA L-arginine derivative having two methyl groups at the N(omega)- and N'(omega)-positionsN(omega),N'(omega)-dimethyl-L-arginine zwitterion; N(omega),N'(omega)-dimethyl-L-arginine

Research

Studies (22,042)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990133 (0.60)18.7374
1990's8,685 (39.40)18.2507
2000's8,445 (38.31)29.6817
2010's4,128 (18.73)24.3611
2020's651 (2.95)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials728 (3.02%)5.53%
Reviews504 (2.09%)6.00%
Case Studies20 (0.08%)4.05%
Observational41 (0.17%)0.25%
Other22,834 (94.64%)84.16%