Page last updated: 2024-08-05 15:30:46

base

A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).

ChEBI ID: 22695

Members (1)

MemberDefinitionClass
piperidineAn azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.piperidine

Research

Studies (771)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990157 (20.36)18.7374
1990's59 (7.65)18.2507
2000's198 (25.68)29.6817
2010's299 (38.78)24.3611
2020's58 (7.52)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews20 (2.49%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other784 (97.51%)84.16%

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
estrogen nuclear receptor alphaHomo sapiens (human)Potency63.853611

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Proton-coupled amino acid transporter 1Homo sapiens (human)Ki54,000.000011