Any bridged diphenyl antifungal agent used for the treatment of fungal infections in humans or animals.
ChEBI ID: 87110
| Member | Definition | Role |
|---|---|---|
| bithionol | An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders. | bithionol |
| fentichlor | An aryl sulfide having two 5-chloro-2-hydroxyphenyl groups attached to sulfur; an antiinfective drug mostly used in veterinary medicine. | fenticlor |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 97 (47.78) | 18.7374 |
| 1990's | 29 (14.29) | 18.2507 |
| 2000's | 22 (10.84) | 29.6817 |
| 2010's | 39 (19.21) | 24.3611 |
| 2020's | 16 (7.88) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (1.26%) | 5.53% |
| Reviews | 14 (5.88%) | 6.00% |
| Case Studies | 41 (17.23%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 180 (75.63%) | 84.16% |