A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
| Member | Definition | Class |
|---|
| 7-deacetylgedunin | A limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica. | 7-deacetylgedunin |
| 8-azahypoxanthine | A triazolopyrimidine that consists of 1,4-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidine bearing an oxo substituent at position 7. | 8-azahypoxanthine |
| acedapsone | A sulfone that is dapsone in which both of the amino groups been acetylation. An antimicrobial drug, it also has antimalarial activity. | acedapsone |
| adefovir | A dimeric naphthopyran with formula C32H26O10, originally isolated from Aspergillus niger. | aurasperone A |
| amodiaquine | A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position. | amodiaquine |
| artemether | An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. | artemether |
| artemisinin | A sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. | (+)-artemisinin |
| artesunate | An artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria. | artesunate |
| asp3026 | A member of the class of diamino-1,3,5-triazines that is 1,3,5-triazine-2,4-diamine in which the amino groups at positions 2 and 4 are respectively carrying 2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl and 2-(propan-2-ylsulfonyl)phenyl substituents. It is a potent inhibitor of anaplastic lymphoma kinase (ALK), Ack and ROS1 activity (IC50 values are 3.5, 5.8 and 8.9 nM respectively) and exhibits anti-cancer properties. | ASP-3026 |
| betulinic acid | A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. | betulinic acid |
| bielschowskysin | A diterpenoid that is isolated from Pseudopterogorgia kallos and exhibits antimalarial and anticancer activity. | bielschowskysin |
| borrelidin | A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties. | borrelidin |
| bromophycolide a | A diterpenoid that is a macrolide isolated from the Fijian red alga Callophycus serratus. It has been found to exhibit moderate cytotoxicity against several human tumour cell lines via specific apotopic cell death. It also displays anti-HIV, antibacterial, antifungal and antimalarial activity. | bromophycolide A |
| caribenol a | A terpene lactone that is 3,4,5,5a,6,7,7a,10,10a,10b-decahydro-2H-1-oxabenzo[cd]cyclopenta[h]azulen-2-one substituted by a hydroxy group at position 10b and methyl groups at positions 3, 6, 9 and 10a. It is isolated from the West Indian gorgonian octocoral Pseudopterogorgia elisabethae and exhibits antitubercular and antimalarial activity. | caribenol A |
| chloroquine | An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis. | chloroquine |
| conessine | A steroid alkaloid that is con-5-enine substituted by a N,N-dimethylamino group at position 3. It has been isolated from the plant species of the family Apocynaceae. | conessine |
| crambescidin 800 | An organic heteropentacyclic guanidine alkaloid isolated from the marine sponge Crambe crambe and Batzella. It exhibits anti-HIV-1 and anti-HSV-1 activity. | crambescidin 800 |
| cryptolepine | An organic heterotetracyclic compound that is 5H-indolo[3,2-b]quinoline in which the hydrogen at position N-5 is replaced by a methyl group. | cryptolepine |
| cycloguanil | A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil. | cycloguanil |
| dapsone | A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. | dapsone |
| dehydroemetine | A pyridoisoquinoline which was developed in response to the cardiovascular toxicity associated with emetine and results from the dehydrogenation of the heterotricylic ring of emetine. It is an antiprotozoal agent and displays antimalarial, antiamoebic, and antileishmanial properties. | dehydroemetine |
| dihydroartemisinin | A sesquiterpenoid compound which is used as a drug for treatment of malaria. | dihydroartemisinin |
| dioncophylline a | An isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 7-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 4,5-dimethoxy-2-methylnaphthalen-1-yl group. It is a naphthylisoquinoline alkaloid isolated from the roots and stem barks of Triphyophyllum peltatum and exhibits antifungal, antimalarial, antineoplastic and molluscicidal activites. | 7-epi-dioncophylline A; dioncophylline A |
| dioncophylline c | An isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 5-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 5-hydroxy-4-methoxy-2-methylnaphthalen-1-yl group. It is a naphthylisoquinoline alkaloid isolated from the roots and stem barks of Triphyophyllum peltatum and exhibits antimalarial activity. | dioncophylline C |
| docetaxel anhydrous | A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group. | docetaxel anhydrous |
| e 64 | | E64 zwitterion; E64 |
| emetine | A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. | emetine |
| emetine dihydrochloride | The dihydrochloride salt of emetine. | emetine dihydrochloride |
| eurycomanone | A quassinoid isolated from Eurycoma longifolia and has been shown to exhibit antineoplastic and antimalarial activties. | eurycomanone |
| gedunin | A pentacyclic triterpenoid natural product found particularly in Azadirachta indica and Cedrela odorata. | gedunin |
| glaucarubinone | A quassinoid with formula C25H34O10. It is a natural product isolated from several plant species and exhibits anti-cancer and anti-malarial properties. | glaucarubinone |
| hydroxychloroquine | An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions. | hydroxychloroquine |
| lactucin | An azulenofuran that is 3-methylidene-3,3a,4,5,9a,9b-hexahydroazuleno[4,5-b]furan-2,7-dione carrying additional hydroxy, methyl and hydroxymethyl substituents at positions 4, 6 and 9 respectively (the 3aR,4S,9aS,9bR-diastereomer). Found in chicory. | lactucin |
| leachianone a | A trihydroxyflavanone that is (2S)-flavanone substituted by a lavandulyl group at position 8, hydroxy groups at positions 5, 7 and 4' and a methoxy group at position 2'. Isolated from the roots of Sophora flavescens and Sophora leachiana, it exhibits antineoplastic and antimalarial activity. | leachianone A |
| lumefantrine | A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria. | lumefantrine |
| lycorine | An indolizidine alkaloid that is 3,12-didehydrogalanthan substituted by hydroxy groups at positions and 2 and a methylenedioxy group across positions 9 and 10. Isolated from Crinum asiaticum, it has been shown to exhibit antimalarial activity. | lycorine |
| manzamine a | An alkaloid of the class of beta-carbolines isolated from Haliclona and Acanthostrongylophora. It exhibits inhibitory activity against Glycogen Synthase Kinase-3 (EC 2.7.11.26). | manzamine A |
| mefloquine | An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown. | (-)-(11S,2'R)-erythro-mefloquine |
| methylene blue | An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties. | methylene blue |
| minquartynoic acid | A straight-chain, C18 polyunsaturated fatty acid having four conjugated C#C bonds at positions 9, 11, 13 and 15 as well as an (S)-hydroxy group at position 17. | minquartynoic acid |
| norlichexanthone | A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 6 and a methyl group at position 8. It has been isolated from Wardomyces anomalus. | norlichexanthone |
| nostocarboline | A member of the class of beta-carbolines that is 9H-beta-carbolin-2-ium substituted by a chloro group at position 6 and a methyl group at position 2. It is isolated from a fresh water cyanobacterium Nostoc 78-12A and acts as an inhibitor of butyrylcholinesterase. | nostocarboline |
| physalin b | A physalin with antimalarial, antitumour and antimicrobial activities isolated from Physalis angulata. | physalin B |
| physalin d | A physalin with antimalarial and antimycobacterial activities isolated from Physalis angulata. | physalin D |
| physalin f | A physalin with antimalarial and antitumour activities isolated from Physalis angulata. | physalin F |
| physalin g | A physalin with antimalarial activity isolated from Physalis angulata. | physalin G |
| piperaquine | An aminoquinoline that is 1,3-di(piperazin-1-yl)propane in which the nitrogen at position 4 of each of the piperazine moieties is replaced by a 7-chloroquinolin-4-yl group. | piperaquine |
| pracinostat | A hydroxamic acid that is N-hydroxyacrylamide which is substituted at position 3 by a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). An orally available pan-histone deacetylase inhibitor with demonstrated activity in the treatment of advanced solid tumours. | pracinostat |
| primaquine | An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia. | primaquine |
| proguanil | A biguanide compound which has isopropyl and p-chlorophenyl substituents on the terminal N atoms. A prophylactic antimalarial drug, it works by inhibiting the enzyme dihydrofolate reductase, which is involved in the reproduction of the malaria parasites Plasmodium falciparum and P. vivax within the red blood cells. | proguanil |
| pyrimethamine | An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis. | pyrimethamine |
| quinacrine | A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9. | quinacrine |
| quinidine | A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. | quinidine |
| quinine | A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy. | quinine |
| simalikalactone D | A quassinoid isolated from Quassia amara and Quassia africana. It has been shown to exhibit antimalarial, cytotoxic and antiviral activities. | simalikalactone D |
| sulfadoxine | A sulfonamide consisting of pyrimidine having methoxy substituents at the 5- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. In combination with the antiprotozoal pyrimethamine (CHEBI:8673) it is used as an antimalarial. | sulfadoxine |
| triacsin c | A nitroso compound that is N-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters. | triacsin C |
| triclosan | An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. | triclosan |
| vexibinol | A tetrahydroxyflavanone having a structure of naringenin bearing an additional hydroxyl substituent at position 2' as well as a (2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl (lavandulyl) substituent at position 8'. | sophoraflavanone G |
| wr-142,490 | An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (+)-(11R,2'S)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown. | (+)-(11R,2'S)-erythro-mefloquine |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 5.3582 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 20.6020 | 2 | 14 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 14.9147 | 4 | 12 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 22.2080 | 2 | 5 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.2000 | 1 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 13.5346 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 16.8462 | 10 | 70 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 22.3539 | 3 | 12 |
| arylsulfatase A | Homo sapiens (human) | Potency | 10.6910 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 7.6058 | 3 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 15.3239 | 2 | 11 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 37.9330 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 19.1257 | 2 | 11 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 22.3961 | 2 | 3 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 69.4562 | 1 | 3 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 33.8009 | 1 | 5 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 42.2620 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 33.8009 | 1 | 5 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 42.2620 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 19.6470 | 3 | 20 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 10.2663 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 23.7358 | 2 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 11.4492 | 2 | 3 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 34.1951 | 1 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 17.7711 | 2 | 5 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 22.3342 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 38.6755 | 2 | 4 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 57.5020 | 2 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 15.8543 | 1 | 7 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 5.0088 | 1 | 9 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 8.9716 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.3841 | 2 | 9 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 19.6227 | 2 | 14 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 19.0440 | 1 | 9 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 11.2202 | 2 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 14.6892 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 6.3143 | 3 | 3 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 8.4882 | 2 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 14.1406 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 32.3912 | 1 | 3 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 39.2465 | 1 | 3 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 24.4561 | 11 | 84 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 37.0980 | 3 | 7 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 13.5238 | 10 | 86 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 36.8199 | 2 | 8 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 15.8081 | 4 | 12 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 22.9005 | 4 | 12 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 29.1761 | 2 | 6 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 33.0836 | 1 | 7 |
| G | Vesicular stomatitis virus | Potency | 15.8543 | 1 | 7 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.9306 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 12.7653 | 4 | 22 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 14.7540 | 3 | 30 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 17.2167 | 1 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 17.9036 | 3 | 14 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 24.3830 | 1 | 9 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 0.5012 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 18.4927 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 36.1692 | 2 | 8 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 0.7943 | 1 | 3 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 33.9972 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 12.3066 | 2 | 4 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 23.8414 | 2 | 16 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 15.8543 | 1 | 7 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 24.0353 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 19.9526 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 31.8362 | 2 | 8 |
| IDH1 | Homo sapiens (human) | Potency | 10.0951 | 1 | 6 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 15.8543 | 1 | 14 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 1.9953 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.3891 | 3 | 30 |
| interleukin 8 | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 52.1194 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 14.5350 | 2 | 11 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 6.3096 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 17.4943 | 2 | 3 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 10.0000 | 1 | 1 |
| luteinizing hormone receptor | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 8.5306 | 2 | 5 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 11.4642 | 1 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 11.3855 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 4.9297 | 3 | 5 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 6.3164 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 58.0479 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 15.4219 | 3 | 25 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 17.4190 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 30.2965 | 2 | 6 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 31.6704 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 27.7170 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 11.7396 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 12.2102 | 3 | 35 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 26.7954 | 1 | 4 |
| Parkin | Homo sapiens (human) | Potency | 18.6919 | 2 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 41.5443 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 18.7303 | 2 | 6 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 0.0757 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 25.2811 | 5 | 20 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 41.4210 | 4 | 9 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 17.7828 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 73.2936 | 3 | 8 |
| PINK1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.8753 | 1 | 5 |
| polyprotein | Zika virus | Potency | 33.0836 | 1 | 7 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 16.3127 | 1 | 5 |
| PPM1D protein | Homo sapiens (human) | Potency | 4.6819 | 1 | 12 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 23.8322 | 3 | 17 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.1187 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 25.0042 | 2 | 11 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 39.8107 | 2 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 16.2993 | 2 | 18 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 32.2327 | 1 | 2 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 12.9683 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 15.4239 | 3 | 24 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 23.1438 | 3 | 10 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 13.0258 | 4 | 4 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 13.8077 | 4 | 6 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 40.0400 | 2 | 6 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 40.0400 | 2 | 6 |
| Smad3 | Homo sapiens (human) | Potency | 11.0729 | 1 | 7 |
| snurportin-1 | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 17.1457 | 2 | 11 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 14.7032 | 1 | 9 |
| T cell receptor, partial | Homo sapiens (human) | Potency | 6.2841 | 1 | 1 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 17.4806 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 8.3603 | 2 | 52 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 31.6228 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 9.6876 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 15.6503 | 3 | 35 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 43.0492 | 3 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 17.3575 | 7 | 22 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 31.1165 | 2 | 3 |
| TSHR protein | Homo sapiens (human) | Potency | 15.5035 | 2 | 2 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 14.6892 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.8753 | 1 | 5 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.8753 | 1 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 29.7322 | 3 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 25.1889 | 2 | 14 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 15.0574 | 2 | 6 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 24.3830 | 1 | 9 |
| Vpr | Human immunodeficiency virus 1 | Potency | 53.0468 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 40.6000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 3-oxoacyl-[acyl-carrier-protein] synthase 3 | Escherichia coli | IC50 | 850.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 2.6630 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.7610 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.1830 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 82.7000 | 1 | 4 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 7.2800 | 1 | 1 |
| 5'-nucleotidase | Mus musculus (house mouse) | IC50 | 68.7900 | 1 | 1 |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase | Plasmodium berghei | IC50 | 12.4100 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 103.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 40.6000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 200.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 119.2223 | 3 | 3 |
| Acidic phospholipase A2 2 | Naja naja (Indian cobra) | IC50 | 2,155.0000 | 2 | 2 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 3.6995 | 3 | 4 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 1.6840 | 3 | 4 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 7.0720 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 6.9410 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Aldehyde oxidase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 10.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 2.8960 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.8720 | 1 | 1 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 41.3000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 3.4185 | 1 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.5000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 1.6805 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.1590 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 2.4703 | 3 | 5 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 1.8250 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 34.9665 | 2 | 3 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 2.0195 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 4.4093 | 3 | 6 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 37.8850 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 94.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 5.9400 | 3 | 5 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 6.2350 | 2 | 2 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 57.7500 | 2 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 10 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 87.7240 | 14 | 25 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 11.5000 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 5.0200 | 5 | 6 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Beta-hexosaminidase subunit alpha | Homo sapiens (human) | IC50 | 11.0833 | 6 | 6 |
| Beta-hexosaminidase subunit beta | Homo sapiens (human) | IC50 | 10.2286 | 7 | 7 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 8.3250 | 3 | 4 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 2.5000 | 1 | 2 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Cryptosporidium parvum | IC50 | 1,000.0000 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum 3D7 | IC50 | 2.4800 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | IC50 | 28.2988 | 10 | 14 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 0.3217 | 11 | 11 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum 3D7 | Ki | 0.0008 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | Ki | 0.2639 | 23 | 40 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium vivax (malaria parasite P. vivax) | Ki | 0.0016 | 1 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 224.0129 | 4 | 24 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 20.0000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | Ki | 14.3000 | 1 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 35.1025 | 3 | 4 |
| Calpain-1 catalytic subunit | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Calpain-1 catalytic subunit | Sus scrofa (pig) | Ki | 3.9600 | 1 | 1 |
| Calpain-9 | Homo sapiens (human) | IC50 | 11.5800 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 10 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | Ki | 0.0600 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 17.0000 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | IC50 | 0.0176 | 4 | 4 |
| Cathepsin B | Homo sapiens (human) | Ki | 16.0000 | 1 | 1 |
| Cathepsin S | Homo sapiens (human) | IC50 | 0.0070 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 39.6500 | 1 | 2 |
| Chain A, enoyl-acyl carrier reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.0500 | 1 | 3 |
| Chain A, Histamine N-methyltransferase | Homo sapiens (human) | Ki | 0.0186 | 1 | 4 |
| Chain C, enoyl-acyl carrier reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.0500 | 1 | 3 |
| Chain E, Fibrin beta chain | Homo sapiens (human) | IC50 | 46.2655 | 2 | 2 |
| Chloroquine resistance transporter | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 68.0000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 70.6233 | 3 | 3 |
| Cholinesterase | Homo sapiens (human) | IC50 | 1.2300 | 1 | 1 |
| Class A sortase SrtA | Staphylococcus aureus | IC50 | 150.0000 | 1 | 1 |
| Cruzipain | Trypanosoma cruzi | IC50 | 35.1050 | 4 | 4 |
| Cyclic GMP-AMP synthase | Homo sapiens (human) | IC50 | 12.3333 | 2 | 3 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 0.0031 | 1 | 1 |
| Cysteine protease | Trypanosoma brucei rhodesiense | Ki | 0.0350 | 1 | 1 |
| Cysteine protease falcipain-3 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.1972 | 3 | 3 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0896 | 8 | 8 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 13.6267 | 3 | 3 |
| cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | IC50 | 19.8800 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.1824 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 0.9900 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 41.7500 | 1 | 2 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 33.2000 | 1 | 2 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 1.4470 | 1 | 2 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 19.4500 | 1 | 2 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 24.4500 | 1 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 2.0632 | 47 | 49 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 3.0286 | 4 | 5 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 0.9900 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 58.8132 | 7 | 11 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.0900 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 1.3180 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.4480 | 1 | 1 |
| Dihydrofolate reductase | Candida albicans | IC50 | 5.0000 | 1 | 1 |
| Dihydrofolate reductase | Escherichia coli K-12 | IC50 | 9.8367 | 3 | 3 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 3.1057 | 7 | 7 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 2.7950 | 9 | 10 |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | IC50 | 1.9092 | 11 | 12 |
| Dihydrofolate reductase | Escherichia coli K-12 | Ki | 0.2230 | 6 | 6 |
| Dihydrofolate reductase | Gallus gallus (chicken) | Ki | 0.1122 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 3.7092 | 10 | 12 |
| Dihydrofolate reductase | Lacticaseibacillus casei | Ki | 17.3780 | 1 | 1 |
| Dihydrofolate reductase | Pneumocystis carinii | Ki | 27.2857 | 3 | 4 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 0.0654 | 2 | 4 |
| Dihydrolipoyl dehydrogenase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1,000.0000 | 1 | 1 |
| Dihydrolipoyl dehydrogenase, mitochondrial | Sus scrofa (pig) | IC50 | 1,000.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 601.0972 | 1 | 4 |
| Dipeptidyl peptidase 1 | Homo sapiens (human) | IC50 | 0.7700 | 1 | 1 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 5.2950 | 2 | 2 |
| DNA gyrase subunit A | Escherichia coli K-12 | IC50 | 1,000.0000 | 1 | 1 |
| DNA gyrase subunit B | Escherichia coli K-12 | IC50 | 1,000.0000 | 1 | 1 |
| DNA ligase | Tequatrovirus T4 | IC50 | 823.0000 | 2 | 4 |
| DNA ligase 1 | Homo sapiens (human) | IC50 | 823.0000 | 2 | 4 |
| DNA ligase A | Mycobacterium tuberculosis H37Rv | IC50 | 823.0000 | 2 | 4 |
| DNA polymerase beta | Homo sapiens (human) | IC50 | 41.1833 | 3 | 3 |
| DNA polymerase beta | Rattus norvegicus (Norway rat) | IC50 | 10.2500 | 2 | 2 |
| DNA-directed RNA polymerase subunit alpha | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| DNA-directed RNA polymerase subunit beta | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| DNA-directed RNA polymerase subunit beta' | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| DNA-directed RNA polymerase subunit omega | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 80.0000 | 2 | 2 |
| Endoplasmic reticulum chaperone BiP | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | IC50 | 2.8712 | 8 | 8 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | Ki | 0.2100 | 4 | 4 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Francisella tularensis subsp. tularensis SCHU S4 | IC50 | 4.3300 | 5 | 5 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 0.5000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | IC50 | 2.9579 | 8 | 12 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Haemophilus influenzae Rd KW20 | IC50 | 7.6425 | 2 | 4 |
| Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | Staphylococcus aureus subsp. aureus MRSA252 | IC50 | 2.6049 | 10 | 14 |
| Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI | Staphylococcus aureus subsp. aureus MRSA252 | Ki | 0.0000 | 1 | 1 |
| Enoyl-ACP reductase II | Streptococcus pneumoniae | IC50 | 32.0000 | 2 | 2 |
| Enoyl-acyl carrier reductase | Toxoplasma gondii | IC50 | 0.0167 | 3 | 3 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0872 | 8 | 8 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.0554 | 17 | 17 |
| Epidermal growth factor receptor | Homo sapiens (human) | GI50 | 1.5080 | 1 | 1 |
| Fatty acid synthase | Rattus norvegicus (Norway rat) | IC50 | 300.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Genome polyprotein | Zika virus | Ki | 92.3000 | 1 | 1 |
| Glucose transporter | Leishmania mexicana | IC50 | 0.0810 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 67.6667 | 3 | 3 |
| Glutathione reductase | Plasmodium falciparum 3D7 | IC50 | 6.4000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 344.1333 | 3 | 3 |
| Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | IC50 | 42.9145 | 3 | 4 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 10.2167 | 6 | 6 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0900 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 6.6716 | 2 | 6 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 3.5350 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 6.2151 | 3 | 7 |
| Histamine H3 receptor | Homo sapiens (human) | Ki | 3.3388 | 5 | 9 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | Ki | 2.7460 | 5 | 11 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 6.6716 | 2 | 6 |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 785,074.7298 | 13 | 16 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 0.0880 | 2 | 2 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 0.0280 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 5.0630 | 2 | 2 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 0.0430 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 0.2080 | 2 | 2 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 0.0270 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 0.0980 | 2 | 2 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 0.0190 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 5.0630 | 2 | 2 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 0.0160 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 2.6195 | 2 | 2 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 0.0210 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 0.1095 | 2 | 2 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 0.2470 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 5.0630 | 2 | 2 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 0.1070 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 1.0337 | 3 | 3 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 0.0480 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 5.0630 | 2 | 2 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 0.0240 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 33.3000 | 1 | 1 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 19.2405 | 2 | 2 |
| Kinesin-like protein KIF11 | Homo sapiens (human) | IC50 | 0.0014 | 8 | 8 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 19.2405 | 2 | 2 |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| Liver carboxylesterase | Sus scrofa (pig) | IC50 | 300.0000 | 1 | 1 |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | IC50 | 15.6150 | 2 | 2 |
| low molecular weight phosphotyrosine protein phosphatase isoform c | Homo sapiens (human) | IC50 | 28.2500 | 2 | 2 |
| Lysosomal protective protein | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Major prion protein | Mus musculus (house mouse) | IC50 | 0.0951 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 9.4250 | 4 | 4 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 150.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 11.2000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Mus musculus (house mouse) | Ki | 0.1450 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 121.3700 | 1 | 10 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 1.4890 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 8.3224 | 2 | 3 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.9575 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 2.7995 | 2 | 4 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 1.2550 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 2.7879 | 2 | 3 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 1.9830 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 3.8423 | 2 | 3 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 3.7360 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 4.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 14.8381 | 2 | 3 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 0.4200 | 1 | 1 |
| N | Leishmania infantum | IC50 | 13.5300 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| NF-kappa-B inhibitor alpha | Homo sapiens (human) | IC50 | 27.1000 | 1 | 1 |
| Non-structural protein 1 | Dengue virus | IC50 | 1.7000 | 1 | 1 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 33.0000 | 1 | 1 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | IC50 | 0.0700 | 1 | 1 |
| Nucleotide-binding oligomerization domain-containing protein 2 | Homo sapiens (human) | IC50 | 5.0119 | 1 | 1 |
| Pancreatic alpha-amylase | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 1 |
| Papain | Carica papaya (papaya) | IC50 | 0.0187 | 3 | 3 |
| Papain | Carica papaya (papaya) | Ki | 5.0800 | 1 | 1 |
| Phosphodiesterase isozyme 4 | Homo sapiens (human) | IC50 | 125.0000 | 1 | 1 |
| Phosphoethanolamine N-methyltransferase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 507.0000 | 1 | 2 |
| Phospholipase A2, membrane associated | Homo sapiens (human) | IC50 | 76,000.0000 | 1 | 1 |
| Phospholipase A2, membrane associated | Rattus norvegicus (Norway rat) | IC50 | 320,000.0000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 1.2388 | 4 | 4 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 0.0230 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 0.5850 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 4.8000 | 1 | 1 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | IC50 | 3.8500 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | IC50 | 2.2000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 4.1172 | 11 | 15 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 3.7685 | 2 | 4 |
| Pro-cathepsin H | Homo sapiens (human) | IC50 | 0.1900 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.9349 | 6 | 6 |
| Procathepsin L | Homo sapiens (human) | Ki | 0.0300 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 219.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 35.0000 | 1 | 1 |
| Pteridine reductase 1 | Leishmania major | IC50 | 13.6000 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 5.4700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 534.1286 | 3 | 7 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 1,221.4900 | 2 | 3 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Ki | 6.7000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 4.5000 | 1 | 2 |
| Serine hydrolase RBBP9 | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Serine hydroxymethyltransferase, mitochondrial | Homo sapiens (human) | IC50 | 0.4365 | 1 | 1 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 54.9000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 75.7000 | 1 | 1 |
| Serum paraoxonase/arylesterase 1 | Homo sapiens (human) | Ki | 291.0000 | 1 | 1 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.7506 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.1027 | 1 | 2 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 11.7500 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 2.8960 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.8720 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.0160 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.0084 | 1 | 1 |
| Sodium/glucose cotransporter 1 | Homo sapiens (human) | IC50 | 18.7000 | 1 | 1 |
| Sodium/glucose cotransporter 2 | Homo sapiens (human) | IC50 | 4.1000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 0.1080 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 0.2800 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 4.7000 | 3 | 4 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | Ki | 3.6000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 6.4575 | 3 | 4 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 50.5925 | 3 | 4 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 20.2000 | 1 | 2 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 2.8000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 21.8667 | 3 | 3 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 3.4000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 37.0500 | 2 | 2 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 42.9850 | 1 | 2 |
| Solute carrier organic anion transporter family member 1A4 | Rattus norvegicus (Norway rat) | Ki | 61.9050 | 1 | 2 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 5.4700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | IC50 | 3.5800 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 5.4700 | 1 | 1 |
| Sterol O-acyltransferase 1 | Homo sapiens (human) | IC50 | 6.3000 | 2 | 2 |
| Sterol O-acyltransferase 2 | Homo sapiens (human) | IC50 | 4.8000 | 1 | 1 |
| Substance-K receptor | Rattus norvegicus (Norway rat) | Ki | 0.0717 | 1 | 1 |
| SUMO-conjugating enzyme UBC9 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| SUMO1 activating enzyme subunit 1 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 9.4000 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 2.9000 | 1 | 1 |
| Toll-like receptor 7 | Homo sapiens (human) | IC50 | 3.4000 | 3 | 3 |
| Toll-like receptor 9 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Transcription factor AP-1 | Homo sapiens (human) | IC50 | 0.0400 | 1 | 1 |
| Transcription factor p65 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 5.4700 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | IC50 | 53.5000 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | IC50 | 133.0000 | 1 | 1 |
| Trypanothione reductase | Trypanosoma cruzi | Ki | 19.0000 | 2 | 2 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 1.5000 | 1 | 1 |
| tyrosine-protein phosphatase non-receptor type 22 isoform 1 | Homo sapiens (human) | IC50 | 80.0000 | 2 | 2 |
| Ubiquitin-like modifier activating enzyme 2 | Homo sapiens (human) | IC50 | 11.2000 | 2 | 2 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 11.7000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 16.6000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 13.1100 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1G | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Voltage-dependent T-type calcium channel subunit alpha-1H | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Zinc finger protein GLI1 | Homo sapiens (human) | IC50 | 21.5533 | 2 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 0.0050 | 1 | 1 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 78.8558 | 4 | 4 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 4.1868 | 1 | 14 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 1.3250 | 1 | 1 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | EC50 | 14.4000 | 1 | 1 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | Kd | 0.1000 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 1.8230 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum K1 | EC50 | 0.0680 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 9.1300 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 0.7040 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 1.4140 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chain A, Repressor | Stenotrophomonas maltophilia | Kd | 0.6300 | 1 | 1 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 2.8200 | 1 | 1 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dihydrofolate reductase | Escherichia coli K-12 | Kd | 2.3604 | 5 | 5 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Egl nine homolog 1 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Env polyprotein | Human immunodeficiency virus 1 | EC50 | 100.0000 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 0.9460 | 2 | 2 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 5.5000 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 20.8270 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 4.0400 | 1 | 1 |
| Estrogen receptor | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 2 |
| Estrogen receptor beta | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 0.0740 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| G-protein coupled bile acid receptor 1 | Homo sapiens (human) | EC50 | 1.0400 | 1 | 1 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Kd | 7.9060 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 9.7220 | 1 | 1 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 3.9780 | 1 | 1 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 5.3060 | 1 | 1 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Major prion protein | Homo sapiens (human) | EC50 | 2.1500 | 1 | 2 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | EC50 | 0.3600 | 2 | 2 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 0.0330 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 3.1500 | 1 | 2 |
| NS5 | Zika virus | EC50 | 0.0308 | 2 | 2 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Nuclear receptor subfamily 4 group A member 2 | Homo sapiens (human) | EC50 | 46.0000 | 4 | 6 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 0.0090 | 1 | 1 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 100.0000 | 1 | 1 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 186.6810 | 1 | 1 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | EC50 | 4.1868 | 1 | 14 |
| Prolyl hydroxylase EGLN2 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Prolyl hydroxylase EGLN3 | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 0.2730 | 1 | 1 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 0.0610 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 0.6270 | 1 | 1 |
| recombinase A | Mycobacterium tuberculosis H37Rv | EC50 | 82.8750 | 2 | 4 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.1868 | 1 | 14 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 4.1868 | 1 | 14 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 4.1868 | 1 | 14 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 4.1868 | 1 | 14 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.1868 | 1 | 14 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Riboflavin-binding protein | Gallus gallus (chicken) | Kd | 1.1820 | 1 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 6.3630 | 1 | 1 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 23.7010 | 1 | 1 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 2.6700 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 0.0700 | 1 | 1 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 0.1230 | 1 | 1 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 12.2010 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 113.8860 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 4.1868 | 1 | 14 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 4.1868 | 1 | 14 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 36.3090 | 1 | 1 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 76.9960 | 2 | 2 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Trace amine-associated receptor 1 | Homo sapiens (human) | EC50 | 10.0000 | 1 | 1 |
| Trace amine-associated receptor 1 | Mus musculus (house mouse) | EC50 | 5.4000 | 1 | 1 |
| Trace amine-associated receptor 5 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 3 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Transcription factor AP-1 | Homo sapiens (human) | EC50 | 0.8100 | 2 | 2 |
| Transmembrane prolyl 4-hydroxylase | Homo sapiens (human) | EC50 | 50.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 4.1868 | 1 | 14 |
| Transthyretin | Homo sapiens (human) | Kd | 144.0000 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 5.2580 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 0.4940 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 0.3630 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 1.1220 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 0.3900 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 1.5330 | 1 | 1 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 1.2470 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 1.2750 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 1.0240 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 0.7810 | 1 | 1 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 0.8220 | 1 | 1 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 113.8860 | 1 | 1 |