Page last updated: 2024-08-05 14:40:25
probe
A role played by a molecular entity used to study the microscopic environment.
ChEBI ID: 50406
Members (2)
| Member | Definition | Class |
|---|
| 6 beta-hydroxycortisol | A C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. | 6beta-hydroxycortisol |
| carbon monoxide | A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. | carbon monoxide |
Research
Studies (18,075)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 6,293 (34.82) | 18.7374 |
| 1990's | 2,112 (11.68) | 18.2507 |
| 2000's | 4,037 (22.33) | 29.6817 |
| 2010's | 4,550 (25.17) | 24.3611 |
| 2020's | 1,083 (5.99) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 743 (3.89%) | 5.53% |
| Reviews | 1,330 (6.97%) | 6.00% |
| Case Studies | 185 (0.97%) | 4.05% |
| Observational | 71 (0.37%) | 0.25% |
| Other | 16,757 (87.80%) | 84.16% |
Protein Targets (5)
Potency Measurements