A role played by a molecular entity used to study the microscopic environment.
ChEBI ID: 50406
| Member | Definition | Class |
|---|---|---|
| 6 beta-hydroxycortisol | A C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. | 6beta-hydroxycortisol |
| carbon monoxide | A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas. | carbon monoxide |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 6,293 (34.82) | 18.7374 |
| 1990's | 2,112 (11.68) | 18.2507 |
| 2000's | 4,037 (22.33) | 29.6817 |
| 2010's | 4,550 (25.17) | 24.3611 |
| 2020's | 1,083 (5.99) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 743 (3.89%) | 5.53% |
| Reviews | 1,330 (6.97%) | 6.00% |
| Case Studies | 185 (0.97%) | 4.05% |
| Observational | 71 (0.37%) | 0.25% |
| Other | 16,757 (87.80%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.5821 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 23.9341 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 2.3270 | 2 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |