Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
Member | Definition | Class |
1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine | A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has octadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. | 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine |
1-hexadecyl-2-acetyl-glycero-3-phosphocholine | A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. | 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine |
aminocaproic acid | An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator. | 6-aminohexanoic acid zwitterion; 6-aminohexanoic acid |
arginine vasopressin | The predominant form of mammalian vasopressin (antidiuretic hormone). It is a nonapeptide containing an arginine at residue 8 and two disulfide-linked cysteines at residues of 1 and 6. | argipressin |
s-nitrosocysteine | An L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor. | S-nitroso-L-cysteine |
ticlopidine | A thienopyridine that is 4,5,6,7-tetrahydrothieno[3,2-c]pyridine in which the hydrogen attached to the nitrogen is replaced by an o-chlorobenzyl group. | ticlopidine |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.0050 | 1 | 1 |
acetylcholinesterase | Homo sapiens (human) | Potency | 5.1288 | 2 | 2 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 11.9669 | 1 | 2 |
AR protein | Homo sapiens (human) | Potency | 15.4467 | 3 | 3 |
arylsulfatase A | Homo sapiens (human) | Potency | 0.3381 | 1 | 1 |
ATAD5 protein, partial | Homo sapiens (human) | Potency | 15.8364 | 2 | 2 |
Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 22.3696 | 2 | 3 |
Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 8.8923 | 1 | 4 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 81.7864 | 2 | 3 |
cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 4.8975 | 1 | 1 |
cytochrome P450 2D6 | Homo sapiens (human) | Potency | 0.5495 | 1 | 1 |
cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 0.3981 | 1 | 1 |
cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 12.3417 | 1 | 2 |
D(1A) dopamine receptor | Homo sapiens (human) | Potency | 0.1299 | 1 | 1 |
Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 8.4368 | 1 | 1 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 19.0224 | 3 | 3 |
euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 7.3260 | 1 | 3 |
EWS/FLI fusion protein | Homo sapiens (human) | Potency | 13.6566 | 3 | 4 |
G | Vesicular stomatitis virus | Potency | 4.8975 | 1 | 1 |
GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
geminin | Homo sapiens (human) | Potency | 0.2060 | 1 | 1 |
glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 4.0664 | 2 | 2 |
heat shock protein beta-1 | Homo sapiens (human) | Potency | 21.1300 | 1 | 1 |
histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 4.8975 | 1 | 1 |
Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 4.8975 | 1 | 2 |
Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 2.2387 | 1 | 1 |
Interferon beta | Homo sapiens (human) | Potency | 4.8975 | 1 | 1 |
lamin isoform A-delta10 | Homo sapiens (human) | Potency | 5.6294 | 1 | 2 |
Luciferase | Photinus pyralis (common eastern firefly) | Potency | 8.7090 | 1 | 1 |
nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 10.0000 | 1 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 26.8325 | 1 | 1 |
nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 18.1382 | 3 | 3 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 19.0115 | 1 | 1 |
peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0642 | 1 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
progesterone receptor | Homo sapiens (human) | Potency | 18.8336 | 1 | 1 |
Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 0.2586 | 1 | 2 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 29.8493 | 1 | 1 |
Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 19.9526 | 1 | 1 |
TDP1 protein | Homo sapiens (human) | Potency | 29.4742 | 1 | 2 |
thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 29.8493 | 2 | 2 |
thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.3981 | 1 | 1 |
thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 19.2704 | 3 | 3 |
ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 25.3735 | 2 | 2 |
vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |