Leukoplakia

A white patch lesion found on a MUCOUS MEMBRANE that cannot be scraped off. Leukoplakia is generally considered a precancerous condition, however its appearance may also result from a variety of HEREDITARY DISEASES.

Synonym
Leukoplakia

Excerpt	Reference
"Leukoplakia is associated with increased risk of oral cancer and is considered a premalignant lesion."	( Elletson, H; Garewal, HS; Kiersch, TA; Killen, D; King, D; Meyskens, FL; Reeves, D; Steinbronn, K; Strosberg, A, 1990)
"Leukoplakia is only a descriptive clinical term designating a white patch or plaque of the mucosa and must be complemented by histology."	( Frangez, I; Gale, N; Luzar, B, 1997)
"In research, oral leukoplakia is used as a model to study the value of chemoprevention as a strategy to prevent cancer, because its effect is directly visible and material for analysis is easily obtainable from the mouth."	( de Vries, N; Pastorino, U; van Zandwijk, N, 1999)
"Leukoplakia is the most common potentially-malignant disorder."	( Ashwatappa, D; Chaudhry, A; Krishna, AG; Krishna, S; Manjunath, M, 2016)
"Laryngeal leukoplakia is a common disorder in otolaryngology."	( Hou, Q; Li, G; Ren, H; Zhang, C, 2022)

Excerpt	Reference
"Crisaborole ointment can effectively treat vulvar leukoplakia, improving the symptoms and pathological changes of the vulvar skin."	( Li, L, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	210 (68.40)	23.3326
1990's	34 (11.07)	12.5806
2000's	23 (7.49)	18.1394
2010's	29 (9.45)	28.8240
2020's	11 (3.58)	9.53

Drug	Relationship Strength	Studies	Trials
aminolevulinic acid	low	6	0
adenine	low	1	0
benzene	low	1	0
salicylic acid	low	1	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	1	0
glycine	low	1	0
niacinamide	low	1	0
niacin	low	1	0
nitrates	low	1	0
nitrous oxide	low	1	0
pyridoxine	low	1	0
uracil	low	1	0
3-methylcholanthrene	low	1	0
albuterol	low	1	0
aspirin	low	1	0
chloroquine	low	4	0
clioquinol	low	1	0
diclofenac	low	1	0
fluconazole	low	1	0
fluorouracil	low	7	0
guaifenesin	low	2	0
2-propanol	low	1	0
khellin	low	3	0
metformin	low	1	0
omeprazole	low	1	0
pioglitazone	low	1	0
praziquantel	medium	1	1
rabeprazole	medium	2	1
sanguinarine	low	2	0
sulfanilamide	low	1	0
urethane	low	1	0
mitomycin	low	1	0
estriol	medium	1	1
thymidine	low	3	0
prednisone	low	2	0
4-nitroquinoline-1-oxide	low	1	0
aspartic acid	low	1	0
9,10-dimethyl-1,2-benzanthracene	low	2	0
bromodeoxyuridine	low	1	0
tyrosine	low	2	0
methylene blue	low	1	0
dimethylnitrosamine	low	1	0
desoxycorticosterone	low	1	0
gallamine triethiodide	low	1	0
triaziquone	low	1	0
triamcinolone acetonide	low	1	0
isoprene	low	1	0
aminacrine	low	1	0
tolonium chloride	low	4	0
framycetin	low	1	0
catechin	low	1	0
acridines	low	5	0
cyclopentane	low	1	0
triethylenephosphoramide	low	1	0
hematoporphyrin	low	2	0
nitrosomethylurethane	low	1	0
6-methyluracil	low	1	0
c.i. 42510	low	1	0
nitrosobenzylmethylamine	low	1	0
deoxyuridine	low	1	0
sodium hydroxide	low	2	0
d-alpha tocopherol	medium	5	1
fucose	low	1	0
carbonates	low	1	0
mercury	low	1	0
neon	low	1	0
tantalum	low	1	0
helium	low	1	0
barium sulfate	low	1	0
iodine	low	2	0
phenyl acetate	low	2	0
triamcinolone	low	1	0
zidovudine	medium	1	1
ribavirin	low	1	0
7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	low	1	0
salmeterol xinafoate	low	1	0
temoporfin	low	1	0
metaperiodate	low	1	0
nicotine	low	11	0
fibrinogen	low	2	0
homocysteine	low	1	0
alphaprodine	low	1	0
methotrexate	low	1	0
1-nitrohydroxyphenyl-n-benzoylalanine	low	1	0
erlotinib hydrochloride	low	1	0
cortisone	low	1	0
benzofurans	low	1	0
glycogen	low	17	0
fibrin	low	1	0
inositol 3-phosphate	low	26	0
tretinoin	medium	5	1
retinol	medium	38	2
tacrolimus	low	1	0
cocaine	low	2	0
lycopene	low	1	0
diethylstilbestrol	low	1	0
riboflavin	low	3	0
bromochloroacetic acid	low	27	0
17-ketosteroids	low	1	0
apigenin	low	1	0
beta carotene	medium	8	3
retinol palmitate	medium	3	1
pulmicort	low	1	0
etretinate	medium	1	1
isotretinoin	medium	5	2
acitretin	medium	2	1
naloxone	low	1	0
fenretinide	low	1	0
morphine	low	1	0
fluticasone	low	1	0
lead	low	1	0
strontium	low	1	0
arsenic	low	4	0
phosphorus	low	1	0
phytochlorin	low	1	0
radium	low	2	0
salvianolic acid B	low	1	0
mocetinostat	low	1	0
nystatin a1	low	1	0
podophyllin	low	1	0
acid phosphatase	low	5	0
methyl jasmonate	low	1	0
pci 32765	low	1	0
piperidines	low	1	0
an2728	medium	1	1
vasoactive intestinal peptide	low	1	0
ascorbic acid	low	4	0
tetracycline	low	2	0
transforming growth factor beta	low	1	0
cyclin d1	low	2	0
vitamin b 12	low	2	0
cyclosporine	low	2	0
orabase	low	1	0
exudates	low	2	0
deoxyguanosine	low	1	0
folic acid	medium	3	1
neopterin	medium	1	1
methylnitronitrosoguanidine	low	1	0
enng	low	1	0
eye	low	2	0
aluminum tetrasulfophthalocyanine	low	1	0
phosphorus radioisotopes	low	2	0

Protein Targets (1,514)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	22	0	0	22
RAR-related orphan receptor gamma	37	0	0	37
GLI family zinc finger 3	42	0	0	42
AR protein	57	0	0	57
aldehyde dehydrogenase 1 family, member A1	43	0	0	43
retinoic acid nuclear receptor alpha variant 1	45	0	0	45
retinoid X nuclear receptor alpha	39	0	0	39
estrogen nuclear receptor alpha	62	0	0	62
peroxisome proliferator-activated receptor delta	31	0	0	31
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	36	0	0	36
activating transcription factor 6	22	0	0	22
v-jun sarcoma virus 17 oncogene homolog (avian)	23	0	0	23
Histone H2A.x	17	0	0	17
thyroid hormone receptor beta isoform a	13	0	0	13
heat shock protein beta-1	25	0	0	25
nuclear factor erythroid 2-related factor 2 isoform 1	40	0	0	40
lamin isoform A-delta10	22	0	0	22
Voltage-dependent calcium channel gamma-2 subunit	29	0	0	29
Glutamate receptor 2	29	0	0	29
Chain A, Phenazine biosynthesis protein phzF	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
thioredoxin reductase	22	0	0	22
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
GLS protein	13	0	0	13
TDP1 protein	46	0	0	46
isocitrate dehydrogenase 1, partial	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	19	0	0	19
DNA polymerase iota isoform a (long)	15	0	0	15
DNA polymerase kappa isoform 1	9	0	0	9
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
Caspase-7	5	0	0	6
Caspase-9	0	0	0	1
large T antigen	0	1	0	1
Luciferase	17	0	0	17
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	15	0	0	15
SMAD family member 2	18	0	0	18
SMAD family member 3	18	0	0	18
Microtubule-associated protein tau	22	0	0	22
caspase 7, apoptosis-related cysteine protease	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	33	0	0	33
estrogen-related nuclear receptor alpha	44	0	0	44
farnesoid X nuclear receptor	26	0	0	26
pregnane X nuclear receptor	36	0	0	36
peroxisome proliferator activated receptor gamma	35	0	0	35
caspase-3	8	0	0	8
euchromatic histone-lysine N-methyltransferase 2	31	0	0	31
aryl hydrocarbon receptor	25	0	0	25
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	21	0	0	21
Cellular tumor antigen p53	38	0	0	38
Cytochrome P450 1A2	0	7	1	8
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	3	1	4
Aldo-keto reductase family 1 member B1	0	8	0	8
Adenosine receptor A3	0	13	0	13
Alpha-1B adrenergic receptor	0	15	1	16
Acetylcholinesterase	0	7	0	7
Sodium-dependent noradrenaline transporter	0	8	1	9
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	15	1	16
Carbonic anhydrase 1	0	17	0	21
Chain A, Beta-lactamase	5	0	0	5
Chain A, HADH2 protein	19	0	0	19
Chain B, HADH2 protein	19	0	0	19
Chain A, Cruzipain	11	0	0	11
acid sphingomyelinase	4	0	0	4
ATAD5 protein, partial	14	0	0	14
apical membrane antigen 1, AMA1	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
thyroid stimulating hormone receptor	14	0	0	14
estrogen receptor 2 (ER beta)	26	0	0	26
progesterone receptor	29	0	0	29
glucocorticoid receptor [Homo sapiens]	44	0	0	44
glucocerebrosidase	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
P53	2	0	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	32	0	0	32
IDH1	15	0	0	15
thyroid stimulating hormone receptor	16	0	0	16
Caspase-7	10	0	0	10
serine-protein kinase ATM isoform a	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	16	0	0	16
chromobox protein homolog 1	18	0	0	18
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
caspase-3	10	0	0	10
thyroid hormone receptor beta isoform 2	39	0	0	39
mitogen-activated protein kinase 1	13	0	0	13
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
ras-related protein Rab-9A	4	0	0	4
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
nuclear receptor ROR-gamma isoform 1	18	0	0	18
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
geminin	39	0	0	39
cytochrome P450 3A4 isoform 1	21	0	0	21
caspase-1 isoform alpha precursor	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	21	1	0	22
Gamma-aminobutyric acid receptor subunit beta-1	21	1	0	22
Gamma-aminobutyric acid receptor subunit delta	21	1	0	22
Gamma-aminobutyric acid receptor subunit gamma-2	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-5	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-3	21	1	0	22
Gamma-aminobutyric acid receptor subunit gamma-1	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-2	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-4	21	1	0	22
Gamma-aminobutyric acid receptor subunit gamma-3	21	1	0	22
Gamma-aminobutyric acid receptor subunit alpha-6	21	1	0	22
Nuclear receptor ROR-gamma	15	1	1	17
Gamma-aminobutyric acid receptor subunit alpha-1	21	4	0	25
Gamma-aminobutyric acid receptor subunit beta-3	21	1	0	22
Gamma-aminobutyric acid receptor subunit beta-2	21	1	0	22
GABA theta subunit	21	1	0	22
ATPase family AAA domain-containing protein 5	21	0	0	21
Ataxin-2	24	0	0	24
Gamma-aminobutyric acid receptor subunit epsilon	21	1	0	22
USP1 protein, partial	20	0	0	20
vitamin D3 receptor isoform VDRA	13	0	0	13
flap endonuclease 1	14	0	0	14
serine/threonine-protein kinase PLK1	5	0	0	5
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	6	0	0	6
peripheral myelin protein 22	20	0	0	20
survival motor neuron protein isoform d	23	0	0	23
histone acetyltransferase KAT2A isoform 1	11	0	0	11
ATP-binding cassette sub-family C member 3	0	28	0	28
Multidrug resistance-associated protein 4	0	28	0	30
Bile salt export pump	0	9	0	9
Bile salt export pump	0	41	0	41
Rap guanine nucleotide exchange factor 3	7	0	0	7
Rap guanine nucleotide exchange factor 4	3	0	0	3
Chain A, Ferritin light chain	14	0	0	14
Smad3	12	0	0	12
alpha-galactosidase	5	0	0	5
DNA topoisomerase 2-alpha	0	0	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	31	0	0	31
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
Cyclin-dependent kinase 1	0	2	1	3
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	5	0	5
TAR DNA-binding protein 43	11	0	0	11
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
glp-1 receptor, partial	13	0	0	13
regulator of G-protein signaling 4	13	0	0	13
NPYLR7B	0	0	2	2
arylsulfatase A	11	0	0	11
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	2	2	4
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-3 adrenergic receptor	0	2	1	3
Delta-type opioid receptor	0	8	4	13
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	4	0	4
Beta-2 adrenergic receptor	0	0	1	3
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Beta-2 adrenergic receptor	0	3	2	5
Canalicular multispecific organic anion transporter 1	0	26	0	26
ATP-dependent phosphofructokinase	12	0	0	12
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	16	0	0	16
67.9K protein	14	0	0	14
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	1	3
Amine oxidase [flavin-containing] A	0	4	0	4
Amine oxidase [flavin-containing] B	0	4	0	4
Trypanothione reductase	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Fumarate hydratase	10	0	0	10
EWS/FLI fusion protein	17	0	0	17
polyprotein	10	0	0	10
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Spike glycoprotein	15	1	2	18
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Beta-lactamase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
PPM1D protein	9	0	0	9
G	17	0	0	17
Interferon beta	23	0	0	23
HLA class I histocompatibility antigen, B alpha chain	17	0	0	17
Replicase polyprotein 1ab	0	3	2	5
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Signal transducer and activator of transcription 3	0	0	1	1
Hexokinase-2	0	1	0	1
Inositol hexakisphosphate kinase 1	17	0	0	17
Bile acid receptor	0	1	0	1
cytochrome P450 2C9, partial	17	0	0	17
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
interleukin 8	13	0	0	13
endonuclease IV	4	0	0	4
BRCA1	2	0	0	2
RGS12	2	0	0	2
15-lipoxygenase, partial	11	0	0	11
NFKB1 protein, partial	6	0	0	6
Thrombopoietin	7	0	0	7
cytochrome P450 2D6	20	0	0	20
Neuraminidase	0	2	0	2
Parkin	5	0	0	5
pyruvate kinase	2	0	0	2
Replicase polyprotein 1ab	0	2	2	4
cytochrome P450 2D6 isoform 1	4	0	0	4
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
peripheral myelin protein 22 isoform 1	9	0	0	9
hemoglobin subunit beta	2	0	0	2
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C19 precursor	5	0	0	5
cytochrome P450 2C9 precursor	2	0	0	2
histone deacetylase 9 isoform 3	6	0	0	6
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	2	0	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5	0	0	5
M-phase phosphoprotein 8	7	0	0	7
pyruvate kinase PKM isoform b	2	0	0	2
neuropeptide S receptor isoform A	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Polyphenol oxidase 2	0	5	0	7
Aldo-keto reductase family 1 member B10	0	3	0	3
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Lysozyme C-1	0	1	0	1
Cationic trypsin	0	1	0	1
Carbonic anhydrase 2	0	17	2	23
Transthyretin	0	0	2	4
Estrogen receptor	0	6	1	7
Glucocorticoid receptor	0	14	2	17
Cytochrome P450 1A1	0	4	0	4
Amyloid-beta precursor protein	1	8	0	9
Integrin beta-3	9	1	0	10
Myeloperoxidase	0	3	0	3
Beta-glucuronidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	4	0	6
ATP-dependent translocase ABCB1	0	3	1	5
Neutrophil elastase	0	2	0	2
Integrin alpha-IIb	9	1	0	10
Ornithine decarboxylase	2	0	0	3
Poly [ADP-ribose] polymerase 1	0	2	0	2
Replicase polyprotein 1a	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Androgen receptor	0	1	0	2
Sialidase	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	3
Aromatase	0	3	0	3
Angiotensin-converting enzyme	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	1	1	2
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Pyruvate kinase PKM	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Urease subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	4	0	4
G2/mitotic-specific cyclin-B	0	1	0	1
Mucin-1	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Casein kinase II subunit alpha'	0	1	1	2
Carbonic anhydrase 4	0	9	0	11
Dipeptidyl peptidase 4	0	2	0	2
Proteasome subunit beta type-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Substance-P receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Prostaglandin G/H synthase 2	0	9	1	11
Mu-type opioid receptor	0	6	2	12
Receptor-type tyrosine-protein kinase FLT3	0	3	1	4
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	1	2	3
Delta-type opioid receptor	0	6	2	12
Kappa-type opioid receptor	0	6	3	13
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	2	2	4
Histamine H2 receptor	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Glycogen synthase kinase-3 alpha	0	1	1	2
Glycogen synthase kinase-3 beta	0	1	1	2
Estrogen receptor	0	0	1	1
Death-associated protein kinase 1	0	2	0	2
Mitogen-activated protein kinase 10	0	1	1	2
Beta-secretase 1	0	3	0	4
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
Lactoperoxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
MO15-related protein kinase Pfmrk	0	2	0	2
Inositol monophosphatase 1	7	0	0	7
Cyclin-dependent kinase 6	0	1	1	2
Cyclin-dependent-like kinase 5	0	1	1	2
Cyclin homolog	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Mitogen-activated protein kinase 14	0	4	1	5
Cytochrome P450 1B1	0	3	0	3
Carbonic anhydrase 3	0	2	0	2
Substance-K receptor	0	1	0	1
Reverse transcriptase/RNaseH	0	3	2	8
Integrase	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Casein kinase II subunit alpha 3	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Estrogen receptor beta	0	4	1	5
Enoyl-acyl-carrier protein reductase	0	1	0	1
Aurora kinase B	0	1	1	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Myocilin	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
Prenyltransferase homolog	0	0	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Estrogen receptor beta	0	0	1	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	0	7
Sialidase-2	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	13	0	0	13
thioredoxin glutathione reductase	7	0	0	7
lethal factor (plasmid)	8	0	0	8
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	9	1	10
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Bloom syndrome protein isoform 1	12	0	0	12
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	4	1	6
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	6
Glutamate receptor ionotropic, NMDA 2B	0	4	1	6
Glutamate receptor ionotropic, NMDA 2C	0	4	1	6
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	4	1	6
Glutamate receptor ionotropic, NMDA 3B	0	4	1	6
Carbonic anhydrase 4	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	4	1	6
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	2	0	0	2
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
muscarinic acetylcholine receptor M1	7	0	0	7
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	3
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Epidermal growth factor receptor	0	5	2	7
Fatty acid-binding protein, liver	0	2	0	2
Prostaglandin G/H synthase 1	0	4	1	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	9
Adenosine receptor A1	0	3	0	4
Adenosine receptor A2a	0	2	0	3
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	6	0	6
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	5	1	6
Sigma non-opioid intracellular receptor 1	0	1	1	2
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	1	1
core protein, partial	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	6
Solute carrier organic anion transporter family member 1B1	0	5	0	6
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	6	0	11
Thymidine phosphorylase	0	0	0	3
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	0	0	2
Thymidylate kinase	0	3	0	3
Carbonic anhydrase	0	5	0	6
Carbonic anhydrase 15	0	7	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
DNA polymerase beta	4	0	0	4
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	1	2
Carbonic anhydrase 6	0	5	0	7
Sucrase-isomaltase, intestinal	0	1	0	1
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Dihydroorotate dehydrogenase	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
thyrotropin-releasing hormone receptor	4	0	0	4
interferon gamma precursor	0	0	0	1
prostaglandin E2 receptor EP2 subtype	0	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	5	0	5
3-phosphoinositide-dependent protein kinase 1	0	1	0	1
Carbonic anhydrase 12	0	3	0	5
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	3	0	3
Carbonic anhydrase 3	0	3	0	5
Procathepsin L	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	1	3	2	7
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Quinolone resistance protein NorA	0	1	0	1
Cytochrome P450 2D6	0	5	1	6
Cytochrome P450 2C9	0	10	2	14
Neuronal acetylcholine receptor subunit beta-2	1	3	2	7
Calpain-2 catalytic subunit	0	2	0	2
5-hydroxytryptamine receptor 1A	0	4	0	4
D(1A) dopamine receptor	0	4	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Cruzipain	0	2	0	2
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	3
Sodium-dependent serotonin transporter	0	8	0	8
Sodium-dependent serotonin transporter	0	4	1	6
Delta-type opioid receptor	0	6	1	9
Mu-type opioid receptor	0	8	3	14
Bifunctional epoxide hydrolase 2	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
Prostaglandin G/H synthase 2	0	3	0	3
Carbonic anhydrase 7	0	3	0	5
Carbonic anhydrase	0	2	0	3
Histone deacetylase 4	0	4	0	4
D(2) dopamine receptor	0	3	0	3
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	9	1	10
Beta-carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Prostaglandin G/H synthase 2	0	3	0	3
Histone deacetylase 1	0	5	0	5
Carbonic anhydrase 9	0	7	0	9
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Carbonic anhydrase	0	2	0	3
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Cyclooxygenase-2	0	1	0	1
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	4	0	4
Histone deacetylase 8	0	4	0	4
P2Y purinoceptor 12	0	2	0	2
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	3	0	3
Carbonic anhydrase 14	0	3	0	5
Histone deacetylase 5	0	4	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	5
Spike glycoprotein	0	1	2	3
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	2
Muscarinic acetylcholine receptor M2	0	4	0	4
Muscarinic acetylcholine receptor M4	0	1	0	1
Cytochrome P450 3A4	0	11	2	14
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	3	1	4
Spike glycoprotein	0	2	0	2
Muscarinic acetylcholine receptor M1	0	3	0	3
Alpha-2C adrenergic receptor	0	3	0	3
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	0	3
Serine/threonine-protein kinase mTOR	0	2	0	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	8	0	8
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	2	3
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
nonstructural protein 1	5	0	0	5
LAP4	0	0	1	1
MEP2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
huntingtin isoform 2	7	0	0	7
heat shock protein HSP 90-alpha isoform 2	0	2	0	4
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Botulinum neurotoxin type A	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Alpha-1D adrenergic receptor	0	4	1	5
Alpha-synuclein	5	5	0	10
Beta-galactosidase	0	0	1	1
Carbonic anhydrase 13	0	2	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	4	1	5
5-hydroxytryptamine receptor 2C	0	4	0	5
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
D	0	2	0	2
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Transporter	0	3	1	5
dopamine D1 receptor	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
Sex hormone-binding globulin	0	0	3	3
Glycine receptor subunit alpha-1	0	14	0	14
Corticosteroid-binding globulin	0	3	0	3
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Discoidin domain-containing receptor 2	0	1	1	2
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain B, Avidin	0	0	1	1
Deoxycytidine kinase	0	0	1	2
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	2	0	2
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
GALC protein	3	0	0	3
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
Dihydrofolate reductase	0	4	0	5
Albumin	0	2	3	5
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	2	0	6
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Cytochrome P450 2J2	0	4	0	4
Solute carrier family 22 member 6	0	2	0	4
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	2
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
5-hydroxytryptamine receptor 4	0	2	0	2
Nuclear receptor subfamily 1 group I member 2	0	1	2	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
D(2) dopamine receptor	0	2	0	2
Androgen receptor	0	4	0	4
Substance-K receptor	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Adenosine receptor A2a	0	3	0	3
Adenosine receptor A1	0	4	0	4
D(3) dopamine receptor	0	4	0	4
Vasopressin V1a receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	6	0	6
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	0	1	1
Aldehyde oxidase	0	1	0	1
UDP-glucose 4-epimerase	0	1	0	1
Cysteinyl leukotriene receptor 1	0	2	0	2
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	4	0	4
ORF73	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Serine/threonine-protein kinase B-raf	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Lanosterol 14-alpha demethylase	0	0	2	2
Olfactory receptor 51E2	0	1	2	3
D(1A) dopamine receptor	3	0	0	3
Glycoprotein hormones alpha chain	2	0	0	2
Retinol-binding protein 4	0	0	3	3
Prosaposin	0	0	1	1
Retinoic acid receptor gamma	0	3	2	8
Alpha-1A adrenergic receptor	0	2	0	2
Retinoic acid receptor RXR-alpha	0	3	2	5
Retinoic acid receptor RXR-beta	0	3	2	5
Retinoic acid receptor RXR-gamma	0	3	2	5
D(1A) dopamine receptor	2	0	0	2
Guanine nucleotide-binding protein G	3	0	0	3
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Lanosterol 14-alpha demethylase	0	1	1	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	1	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	2	0	0	2
muscleblind-like protein 1 isoform 1	5	0	0	5
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	4	0	5
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	2	0	2
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	1	0	1
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	3	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	2	0	3
Cytochrome P450 2A6	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Cytochrome P450 2C19	0	5	1	8
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	3
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	2	1	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 1	0	1	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	2	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Kappa-type opioid receptor	0	4	3	8
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	4
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	3
Protein-arginine deiminase type-4	0	2	0	2
Chain E, Fibrin beta chain	0	2	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	3	0	0	3
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	3	1	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	3	1	4
Muscarinic acetylcholine receptor M4	0	4	1	5
Muscarinic acetylcholine receptor M5	0	3	1	4
Muscarinic acetylcholine receptor M2	0	3	1	4
Translocator protein	0	1	1	2
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	3	1	6
Kappa-type opioid receptor	0	4	1	5
Mu-type opioid receptor	0	3	1	7
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Sodium/iodide cotransporter	0	1	0	1
Mcl-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Fatty acid synthase	0	4	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	2	0	2
Glutathione S-transferase omega-1	0	2	0	2
Histone-lysine N-methyltransferase 2A	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	2	0	2
Muscarinic acetylcholine receptor	0	1	0	1
tyrosine-protein kinase Yes	3	0	0	3
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	2
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	0	2
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Solute carrier family 22 member 3	0	1	0	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	1	2
Insulin receptor	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	0	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Cytochrome P450 2B6	0	1	1	3
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	1	1	2
G protein-coupled receptor kinase 6	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	2	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	1	1	2
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Peroxiredoxin-like 2A	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Platelet glycoprotein VI	0	1	0	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	0	1
Steryl-sulfatase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	2	0	4
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	0	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	2	5
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Progesterone receptor	0	1	0	1
Glucocorticoid receptor	0	1	0	1
Mineralocorticoid receptor	0	1	1	2
Matrix metalloproteinase-9	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Beta-lactoglobulin	0	0	1	1
NS5	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
tumor necrosis factor	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
inositol monophosphatase 1	1	0	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
beta-2 adrenergic receptor	1	0	1	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
galanin receptor type 3	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
phospholipase A2, group III	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Cholinesterase	0	2	0	2
Alanine aminotransferase 1	0	0	0	2
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Regulator of G-protein signaling 17	0	1	1	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Protein argonaute-2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Thymidine kinase	0	1	0	2
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	3
Thymidine kinase	0	2	0	4
Thymidine kinase	0	1	0	3
Thymidine kinase	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Nuclear receptor ROR-alpha	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Plasma kallikrein	0	0	0	1
SLC16A10 protein	0	0	0	1
Tubulin--tyrosine ligase	0	1	0	1
Monocarboxylate transporter 10	0	0	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
DNA polymerase beta	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protease	0	1	1	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (307)

Protein Targets (1,514)

Leukoplakia

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (307)

Drugs Studied (166)

Protein Targets (1,514)