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Mycoplasma genitalium metabolite

Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.

ChEBI ID: 131604

Members (38)

MemberDefinitionClass
2-deoxyglucose-6-phosphateA deoxyaldohexose phosphate comprising 2-deoxy-D-glucose having the phosphate group at the 6-position.2-deoxy-D-glucose 6-phosphate
2-phenyl-2-propanolA tertiary alcohol that is isopropanol in which the hydrogen attached to the carbon bearing the hydroxy group has been replaced by a phenyl group.2-phenylpropan-2-ol
2'-deoxycytidine diphosphateA 2'-deoxycytidine phosphate that is the 2'- deoxy derivative of cytidine 5'-diphosphate (CDP).dCDP
5-(carboxymethylaminomethyl)-2-thiouridineA thiouridine that is 2-thiouridine bearing an additional carboxymethylaminomethyl substituent at position 5 on the thiouracil ring.5-carboxymethylaminomethyl-2-thiouridine
5,6-dihydrothymidineA pyrimidine 2'-deoxyribonucleoside having dihydrothymine as the nucleobase.5,6-dihydrothymidine
6-azathymineA nucleobase analogue that is thymine in which the CH group at position 6 is replaced by nitrogen.6-azathymine
8-azaadenineA triazolopyrimidine that is [1,2,3]triazolo[4,5-d]pyrimidine bearing an amino substituent at position 7.8-azaadenine
8,5'-cyclo-2'-deoxyadenosineAn organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of 2'-deoxyadenosine.8,5'-cyclo-2'-deoxyadenosine
8,5'-cyclo-2'-deoxyguanosineAn organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of 2'-deoxyguanosine.8,5'-cyclo-2'-deoxyguanosine
adenosine 5'-phosphoramidateThe phosphoramadite analogue of AMP.adenosine 5'-phosphoramidate
alanylalanineA dipeptide consisting of two L-alanine units joined by a peptide linkage.Ala-Ala zwitterion; L-alanyl-L-alanine
arginylarginineA dipeptide formed from two L-arginine residues.Arg-Arg
aspartyl-aspartic acidA dipeptide formed from two L-aspartic acid units.Asp-Asp
butyric acidA straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.butyric acid
chloramphenicolAn organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions.chloramphenicol
cifostodineA 2',3'-cyclic pyrimidine nucleotide in which cytidine is the parent nucleoside.2',3'-cyclic CMP
cumene hydroperoxideA peroxol that is cumene in which the alpha-hydrogen is replaced by a hydroperoxy group.cumene hydroperoxide
cyclic diadenosine phosphateA cyclic purine dinucleotide that is the 3',5'-cyclic dimer of AMP.cyclic di-AMP
cysteinylcysteineA dipeptide formed from two L-cysteine residues.Cys-Cys
deoxydiguanosine diphosphosphateA single-stranded DNA oligonucleotide comprising two 2'-deoxyguanosine residues connected by a 3'->5 linkage and with a phosphoric group at the 5'-terminus.5'-d(pGpG)-3'
deoxyinosine monophosphateA deoxyinosine phosphate that is 5'-inosinic acid in which the hydroxy group at position 2' by a hydrogen atom.2'-deoxyinosine-5'-monophosphate
difloxacinA quinolone that is pefloxacin in which the ethyl group at position 1 of the quinolone has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usually as the monohydrochloride salt) for the treatment of bacterial infections in dogs.difloxacin
glutamyl-glutamic acidA dipeptide composed of two L-glutamic acid units joined by a peptide linkage.Glu-Glu
histidylhistidineA dipeptide formed from two L-histidine residues.His-His
isodialuric acidA nucleobase analogue that is uracil substituted at positions 5 and 6 by hydroxy groups.5,6-dihydroxyuracil
leucylleucineA dipeptide formed from two L-leucine residues.Leu-Leu zwitterion; Leu-Leu
lysyllysineA dipeptide formed from two L-lysine residues.Lys-Lys
menaquinone 7A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.menaquinone-7
methanolThe primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.methanol
n-palmitoylsphingosineA N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl).N-hexadecanoylsphingosine
phenylalanylphenylalanineA dipeptide formed from two L-phenylalanine residues.Phe-Phe zwitterion; Phe-Phe
prolyl-prolineA dipeptide formed from two L-proline residues.Pro-Pro
s-adenosylmethionineA sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine.S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine
streptogramin aA macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus.pristinamycin IIA
Trp-TrpA dipeptide formed from two L-tryptophan residues.Trp-Trp
tryptophyl adenylateAn L-tryptophan derivative that is the ester obtained by formal condensation of the carboxy group of L-tryptophan with the 3'-hydroxy group of AMP.3'-L-tryptophyl-AMP
tyrosyltyrosineTyrosyltyrosine in which each tyrosine residue has L-configuration.Tyr-Tyr
valylvalineA dipeptide formed from two L-valine residues.Val-Val

Research

Studies (58,680)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199023,264 (39.65)18.7374
1990's5,385 (9.18)18.2507
2000's9,710 (16.55)29.6817
2010's15,166 (25.85)24.3611
2020's5,155 (8.78)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials896 (1.44%)5.53%
Reviews2,357 (3.79%)6.00%
Case Studies2,193 (3.52%)4.05%
Observational33 (0.05%)0.25%
Other56,737 (91.19%)84.16%

Protein Targets (150)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-lipoxygenase, partialHomo sapiens (human)Potency0.125911
activating transcription factor 6Homo sapiens (human)Potency31.257812
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency26.968012
AR proteinHomo sapiens (human)Potency21.016044
aryl hydrocarbon receptorHomo sapiens (human)Potency76.958811
Cellular tumor antigen p53Homo sapiens (human)Potency15.355311
cytochrome P450 2C9, partialHomo sapiens (human)Potency89.358411
cytochrome P450 2D6Homo sapiens (human)Potency89.358411
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency60.404312
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency89.125111
estrogen nuclear receptor alphaHomo sapiens (human)Potency31.675147
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency26.615046
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency3.981111
EWS/FLI fusion proteinHomo sapiens (human)Potency0.020912
farnesoid X nuclear receptorHomo sapiens (human)Potency27.298311
GVesicular stomatitis virusPotency89.358411
gemininHomo sapiens (human)Potency0.005522
GLI family zinc finger 3Homo sapiens (human)Potency17.571423
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency8.485211
heat shock protein beta-1Homo sapiens (human)Potency56.402023
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency14.162612
Histone H2A.xCricetulus griseus (Chinese hamster)Potency44.987811
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency39.810711
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency89.358411
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency89.358412
Interferon betaHomo sapiens (human)Potency89.358411
interleukin 8Homo sapiens (human)Potency66.824211
lamin isoform A-delta10Homo sapiens (human)Potency17.782811
lethal factor (plasmid)Bacillus anthracis str. A2012Potency31.622811
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency48.555736
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency0.500412
Nuclear receptor ROR-gammaHomo sapiens (human)Potency42.163211
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency35.481311
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency38.668923
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency24.541211
pregnane X nuclear receptorHomo sapiens (human)Potency70.794611
progesterone receptorHomo sapiens (human)Potency65.739811
RAR-related orphan receptor gammaMus musculus (house mouse)Potency48.957124
regulator of G-protein signaling 4Homo sapiens (human)Potency0.211911
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency45.630524
SMAD family member 2Homo sapiens (human)Potency23.006511
SMAD family member 3Homo sapiens (human)Potency23.006511
TDP1 proteinHomo sapiens (human)Potency9.396027
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency41.681034
thyroid stimulating hormone receptorHomo sapiens (human)Potency30.979555
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency30.961034

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
30S ribosomal protein S1Escherichia coli K-12IC500.430011
30S ribosomal protein S10Escherichia coli K-12IC500.430011
30S ribosomal protein S11Escherichia coli K-12IC500.430011
30S ribosomal protein S12Escherichia coli K-12IC500.430011
30S ribosomal protein S13Escherichia coli K-12IC500.430011
30S ribosomal protein S14Escherichia coli K-12IC500.430011
30S ribosomal protein S15Escherichia coli K-12IC500.430011
30S ribosomal protein S16Escherichia coli K-12IC500.430011
30S ribosomal protein S17Escherichia coli K-12IC500.430011
30S ribosomal protein S18Escherichia coli K-12IC500.430011
30S ribosomal protein S19Escherichia coli K-12IC500.430011
30S ribosomal protein S2Escherichia coli K-12IC500.430011
30S ribosomal protein S20Escherichia coli K-12IC500.430011
30S ribosomal protein S21Escherichia coli K-12IC500.430011
30S ribosomal protein S3Escherichia coli K-12IC500.430011
30S ribosomal protein S4Escherichia coli K-12IC500.430011
30S ribosomal protein S5Escherichia coli K-12IC500.430011
30S ribosomal protein S6Escherichia coli K-12IC500.430011
30S ribosomal protein S7Escherichia coli K-12IC500.430011
30S ribosomal protein S8Escherichia coli K-12IC500.430011
30S ribosomal protein S9Escherichia coli K-12IC500.430011
50S ribosomal protein L1Escherichia coli K-12IC500.430011
50S ribosomal protein L10Escherichia coli K-12IC500.430011
50S ribosomal protein L11Escherichia coli K-12IC500.430011
50S ribosomal protein L13Escherichia coli K-12IC500.430011
50S ribosomal protein L14Escherichia coli K-12IC500.430011
50S ribosomal protein L15Escherichia coli K-12IC500.430011
50S ribosomal protein L16Escherichia coli K-12IC500.430011
50S ribosomal protein L17Escherichia coli K-12IC500.430011
50S ribosomal protein L18Escherichia coli K-12IC500.430011
50S ribosomal protein L19Escherichia coli K-12IC500.430011
50S ribosomal protein L2Escherichia coli K-12IC500.430011
50S ribosomal protein L20Escherichia coli K-12IC500.430011
50S ribosomal protein L21Escherichia coli K-12IC500.430011
50S ribosomal protein L22Escherichia coli K-12IC500.430011
50S ribosomal protein L23Escherichia coli K-12IC500.430011
50S ribosomal protein L24Escherichia coli K-12IC500.430011
50S ribosomal protein L25Escherichia coli K-12IC500.430011
50S ribosomal protein L27Escherichia coli K-12IC500.430011
50S ribosomal protein L28Escherichia coli K-12IC500.430011
50S ribosomal protein L29Escherichia coli K-12IC500.430011
50S ribosomal protein L3Escherichia coli K-12IC500.430011
50S ribosomal protein L30Escherichia coli K-12IC500.430011
50S ribosomal protein L31Escherichia coli K-12IC500.430011
50S ribosomal protein L31 type BEscherichia coli K-12IC500.430011
50S ribosomal protein L32Escherichia coli K-12IC500.430011
50S ribosomal protein L33Escherichia coli K-12IC500.430011
50S ribosomal protein L34Escherichia coli K-12IC500.430011
50S ribosomal protein L35Escherichia coli K-12IC500.430011
50S ribosomal protein L36Escherichia coli K-12IC500.430011
50S ribosomal protein L36 2Escherichia coli K-12IC500.430011
50S ribosomal protein L4Escherichia coli K-12IC500.430011
50S ribosomal protein L5Escherichia coli K-12IC500.430011
50S ribosomal protein L6Escherichia coli K-12IC500.430011
50S ribosomal protein L7/L12Escherichia coli K-12IC500.430011
Angiotensin-converting enzyme Homo sapiens (human)IC50616.595011
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
Bile salt export pumpHomo sapiens (human)IC50408.633333
Chain A, Nitrile Hydratase alpha subunitPseudonocardia thermophilaKi1,300.000011
Chain A, Oligo-peptide Binding ProteinSalmonella enterica subsp. enterica serovar TyphimuriumKi125.000011
Chain B, Nitrile Hydratase beta subunitPseudonocardia thermophilaKi1,300.000011
Cytochrome P450 3A4Homo sapiens (human)Ki10.600011
EndoplasminHomo sapiens (human)Ki10.000011
Glutamate carboxypeptidase 2Rattus norvegicus (Norway rat)IC500.750011
Glutamate receptor 1Homo sapiens (human)Ki260.000012
Glutamate receptor 2Homo sapiens (human)Ki260.000012
Glutamate receptor 3Homo sapiens (human)Ki260.000012
Glutamate receptor 4Homo sapiens (human)Ki260.000012
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)Ki260.000012
Heat shock protein HSP 90-alphaHomo sapiens (human)Ki3.000011
Histone deacetylase 1Homo sapiens (human)IC50158.000022
Histone deacetylase 1Homo sapiens (human)Ki136.000011
Histone deacetylase 11 Homo sapiens (human)Ki136.000011
Histone deacetylase 2Homo sapiens (human)IC50206.000022
Histone deacetylase 2Homo sapiens (human)Ki136.000011
Histone deacetylase 3Homo sapiens (human)IC509.000011
Histone deacetylase 3Homo sapiens (human)Ki136.000011
Histone deacetylase 4Homo sapiens (human)IC502,000.000011
Histone deacetylase 4Homo sapiens (human)Ki136.000011
Histone deacetylase 5Homo sapiens (human)IC502,000.000011
Histone deacetylase 5Homo sapiens (human)Ki136.000011
Histone deacetylase 6Homo sapiens (human)IC502,000.000011
Histone deacetylase 6Homo sapiens (human)Ki136.000011
Histone deacetylase 7Homo sapiens (human)IC501,150.000022
Histone deacetylase 7Homo sapiens (human)Ki136.000011
Histone deacetylase 8Homo sapiens (human)IC5015.000011
Histone deacetylase 8Homo sapiens (human)Ki136.000011
Histone deacetylase 9Homo sapiens (human)IC502,000.000011
Histone deacetylase 9Homo sapiens (human)Ki136.000011
Lysine-specific demethylase 4EHomo sapiens (human)IC5010,000.000011
Mu-type opioid receptorCavia porcellus (domestic guinea pig)IC501,963.6364111
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000011
Polyamine deacetylase HDAC10Homo sapiens (human)Ki136.000011
Solute carrier family 15 member 1Homo sapiens (human)IC501,805.2500212
Solute carrier family 15 member 1Homo sapiens (human)Ki569.750038
Solute carrier family 15 member 1Rattus norvegicus (Norway rat)Ki4,495.000012
Solute carrier family 15 member 2Homo sapiens (human)Ki43.903329
Solute carrier family 15 member 2Rattus norvegicus (Norway rat)Ki123.000012
Solute carrier family 22 member 20Mus musculus (house mouse)Ki81.641612
Solute carrier family 22 member 6Mus musculus (house mouse)Ki3,483.685012
Thymidine kinase 2 Rattus norvegicus (Norway rat)Ki77.000011
Tripeptidyl-peptidase 2Rattus norvegicus (Norway rat)Ki1,670.000011
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)IC503.800011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
EndoplasminHomo sapiens (human)Kd50.000011
Free fatty acid receptor 3Homo sapiens (human)EC5012.000011
Heat shock protein HSP 90-alphaHomo sapiens (human)Kd50.000011
Methionine--tRNA ligase, mitochondrialHomo sapiens (human)EC507.900011
Methyl-accepting chemotaxis protein NahYPseudomonas putidaKd92.000011
Solute carrier family 15 member 1Homo sapiens (human)EC50418.750018
Stimulator of interferon genes proteinHomo sapiens (human)EC503.287377
streptokinase A precursorStreptococcus pyogenes M1 GASEC500.973011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
5-hydroxytryptamine receptor 1DHomo sapiens (human)KA65.500012
Carbonic anhydrase 1Homo sapiens (human)KA44.500012
Carbonic anhydrase 2Homo sapiens (human)KA65.500012
Carbonic anhydrase 4Bos taurus (cattle)KA56.500012
Dihydroxyacetone phosphate acyltransferaseHomo sapiens (human)Radius of inhibition zone9,214.285777