Dysautonomia, Familial

An autosomal disorder of the peripheral and autonomic nervous systems limited to individuals of Ashkenazic Jewish descent. Clinical manifestations are present at birth and include diminished lacrimation, defective thermoregulation, orthostatic hypotension (HYPOTENSION, ORTHOSTATIC), fixed pupils, excessive SWEATING, loss of pain and temperature sensation, and absent reflexes. Pathologic features include reduced numbers of small diameter peripheral nerve fibers and autonomic ganglion neurons. (From Adams et al., Principles of Neurology, 6th ed, p1348; Nat Genet 1993;4(2):160-4)

Synonym
Dysautonomia, Familial

Excerpt	Reference
"Familial dysautonomia is a rare inherited disease of the nervous system, involving mainly peripheral sensory and sympathetic nerves."	( Sigurdsson, J; Stenqvist, O, 1982)
"Familial dysautonomia is a challenging condition for the eye because of the presence of alacrymia and lack of corneal sensitivity."	( Carrasquillo, K; Michaud, L, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	249 (76.15)	23.3326
1990's	11 (3.36)	12.5806
2000's	26 (7.95)	18.1394
2010's	34 (10.40)	28.8240
2020's	7 (2.14)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
aminolevulinic acid	low	1	0
adenine	low	1	0
ammonium hydroxide	low	1	0
chlorine	low	2	0
hydrochloric acid	low	2	0
3,4-dihydroxyphenylacetic acid	low	1	0
creatine	low	2	0
histamine	low	17	0
iodine	low	3	0
dihydroxyphenylalanine	low	4	0
nitrous oxide	low	2	0
porphobilinogen	low	1	0
thiamine	low	3	0
urea	low	3	0
normetanephrine	low	1	0
vanilmandelic acid	low	6	0
homovanillic acid	low	3	0
hydroxyindoleacetic acid	low	3	0
theophylline	low	1	0
amitriptyline	low	2	0
amobarbital	low	1	0
aspirin	low	1	0
azathioprine	low	1	0
bemegride	low	1	0
bromhexine	low	1	0
carbamazepine	low	1	0
chlordiazepoxide	low	1	0
chlorpromazine	low	3	0
clonidine	medium	3	1
desipramine	low	1	0
diazepam	medium	7	1
disulfiram	low	1	0
domperidone	low	1	0
fentanyl	low	2	0
fluphenazine	low	1	0
flumazenil	low	1	0
haloperidol	low	1	0
halothane	low	1	0
hydroxyzine	low	1	0
phenelzine	low	1	0
imipramine	low	2	0
isoflurane	low	1	0
2-propanol	low	2	0
isoproterenol	low	2	0
ketamine	low	1	0
kinetin	low	13	0
meprobamate	low	2	0
metaproterenol	low	1	0
methoxyflurane	low	1	0
metoclopramide	medium	1	1
midazolam	medium	2	1
midodrine	medium	1	1
apnea	low	2	0
neostigmine	low	6	0
oxazepam	low	5	0
perphenazine	low	1	0
phenacetin	low	1	0
phenobarbital	medium	4	1
phenoxybenzamine	low	1	0
potassium chloride	low	2	0
probenecid	low	1	0
procaine	low	2	0
promethazine	low	1	0
propofol	low	2	0
propranolol	low	8	0
secobarbital	low	1	0
succinylcholine	low	3	0
thalidomide	low	1	0
thioridazine	low	1	0
tyramine	low	4	0
estriol	medium	4	1
phentolamine	low	1	0
thyroxine	low	1	0
carbachol	low	2	0
aldosterone	low	5	0
penicillamine	low	1	0
prednisone	low	1	0
pilocarpine	low	2	0
pentylenetetrazole	low	1	0
alanine	low	2	0
chloramphenicol	low	1	0
lysine	low	1	0
physostigmine	low	1	0
sucrose	low	2	0
ethinyl estradiol	medium	4	2
tubocurarine	low	2	0
phenylephrine	low	2	0
levodopa	low	2	0
tyrosine	low	2	0
methacholine chloride	low	4	0
methandrostenolone	low	1	0
phencyclidine	low	1	0
trichloroethylene	low	1	0
dehydrocholic acid	medium	1	1
xanthenes	low	1	0
pyridostigmine bromide	low	2	0
ergotamine	low	8	0
ambenonium chloride	low	1	0
methohexital	low	1	0
catechin	low	2	0
quinazolines	low	1	0
acridines	low	1	0
thiazoles	low	1	0
ephedrine	low	4	0
opipramol	medium	5	1
betamethasone	low	1	0
prenylamine	low	1	0
limestone	low	1	0
dihydroergotamine	low	1	0
echothiophate iodide	low	1	0
medroxyprogesterone	medium	3	1
methoxyhydroxyphenylglycol	low	3	0
chlorotrianisene	low	2	0
clopenthixol	low	1	0
d-alpha tocopherol	low	2	0
metanephrine	low	1	0
barium sulfate	low	2	0
trolamine salicylate	low	1	0
fludrocortisone	medium	6	1
substance p	low	2	0
propiconazole	low	1	0
atracurium	low	1	0
fomesafen	low	20	0
epigallocatechin gallate	low	2	0
amezinium	low	1	0
methotrimeprazine	low	2	0
nicotine	low	1	0
fibrinogen	low	1	0
3,4-dihydroxyphenylglycol	low	2	0
valerates	low	1	0
5-fluorodopamine	low	1	0
angiotensin ii	low	5	0
atropine	low	7	0
cortisone	low	3	0
bortezomib	low	1	0
lanatosides	low	1	0
bradykinin	low	2	0
glucosamine	low	1	0
inositol 3-phosphate	low	3	0
indican	low	1	0
carnosol	low	1	0
acetyl coenzyme a	low	1	0
cocaine	low	3	0
capsaicin	low	1	0
digoxin	low	1	0
thiouridine	low	1	0
17-ketosteroids	low	3	0
genistein	low	1	0
daidzein	low	1	0
tocotrienol, delta	low	1	0
phenylephrine hydrochloride	low	1	0
dexmedetomidine	low	3	0
lead	low	1	0
barium	low	1	0
thallium	low	1	0
sulfur	low	1	0
veratrine	low	1	0
phosphorus	low	1	0
pregabalin	low	1	0
oxalates	low	1	0
pregnanediol	low	1	0
pridopidine	low	1	0
tocotrienols	medium	6	1
scopolamine hydrobromide	low	1	0
pituitrin	low	3	0
atrial natriuretic factor	medium	3	2
oligonucleotides	low	1	0
sodium salicylate	low	1	0
sodium ethylxanthate	low	1	0
piperidines	low	3	0
heme	low	1	0
tetracycline	low	1	0
salicylates	low	1	0
globotriaosylceramide	low	1	0
vitamin b 12	low	1	0
lactoferrin	low	1	0
muramidase	low	1	0
methylnitronitrosoguanidine	low	1	0
eye	low	9	0
carbidopa	medium	2	2

Protein Targets (1,392)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
RAR-related orphan receptor gamma	42	0	0	42
GLI family zinc finger 3	43	0	0	43
AR protein	56	0	0	56
aldehyde dehydrogenase 1 family, member A1	33	0	0	33
retinoic acid nuclear receptor alpha variant 1	36	0	0	36
retinoid X nuclear receptor alpha	26	0	0	26
estrogen nuclear receptor alpha	61	0	0	61
peroxisome proliferator-activated receptor delta	24	0	0	24
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	27	0	0	27
activating transcription factor 6	20	0	0	20
v-jun sarcoma virus 17 oncogene homolog (avian)	27	0	0	27
Histone H2A.x	19	0	0	19
thyroid hormone receptor beta isoform a	16	0	0	16
heat shock protein beta-1	16	0	0	16
nuclear factor erythroid 2-related factor 2 isoform 1	44	0	0	44
lamin isoform A-delta10	45	0	0	45
Voltage-dependent calcium channel gamma-2 subunit	22	0	0	22
Glutamate receptor 2	23	0	0	23
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	29	0	0	29
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
Chain A, JmjC domain-containing histone demethylation protein 3A	6	0	0	6
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
Chain A, Protocatechuate 3,4-dioxygenase	0	0	1	1
Chain M, Protocatechuate 3,4-dioxygenase	0	0	1	1
Olfactory receptor class A-like protein 1	0	0	1	1
Luciferase	16	0	0	16
endonuclease IV	7	0	0	7
thioredoxin reductase	41	0	0	41
RGS12	1	0	0	1
phosphopantetheinyl transferase	19	0	0	19
NFKB1 protein, partial	15	0	0	15
GLS protein	35	0	0	35
TDP1 protein	56	0	0	56
Microtubule-associated protein tau	27	0	0	27
Thrombopoietin	10	0	0	10
alkaline phosphatase, intestinal	0	0	1	1
thioredoxin glutathione reductase	6	0	0	6
apical membrane antigen 1, AMA1	7	0	0	7
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	13	0	0	13
thyroid stimulating hormone receptor	22	0	0	22
hypothetical protein, conserved	4	0	0	4
regulator of G-protein signaling 4	31	0	0	31
euchromatic histone-lysine N-methyltransferase 2	56	0	0	56
Bloom syndrome protein isoform 1	19	0	0	19
lysosomal alpha-glucosidase preproprotein	5	0	0	5
peripheral myelin protein 22 isoform 1	11	0	0	11
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
intestinal alkaline phosphatase precursor	0	1	0	1
chromobox protein homolog 1	33	0	0	33
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
DNA polymerase beta	5	0	0	5
flap endonuclease 1	11	0	0	11
DNA polymerase iota isoform a (long)	18	0	0	18
geminin	46	0	0	46
M-phase phosphoprotein 8	18	0	0	18
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
POsterior Segregation	0	0	2	2
muscarinic acetylcholine receptor M1	23	0	0	23
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	28	3	31
Zinc finger protein mex-5	0	0	2	2
ATP-dependent phosphofructokinase	23	0	0	23
Alpha-1B adrenergic receptor	0	29	4	33
Beta-1 adrenergic receptor	0	7	2	11
Alpha-2B adrenergic receptor	0	17	4	21
Alpha-2C adrenergic receptor	0	17	4	21
Alpha-2A adrenergic receptor	0	17	4	21
Alpha-1D adrenergic receptor	0	22	4	27
Alpha-1A adrenergic receptor	0	30	5	35
Beta-2 adrenergic receptor	0	3	0	3
N-alpha-acetyltransferase 50	0	0	1	1
Chain A, Ferritin light chain	10	0	0	10
Smad3	11	0	0	11
alpha-galactosidase	6	0	0	6
DNA topoisomerase 2-alpha	0	0	0	1
Acetylcholinesterase	0	7	0	8
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	34	0	0	34
cytochrome P450 family 3 subfamily A polypeptide 4	32	0	0	32
glucocorticoid receptor [Homo sapiens]	46	0	0	46
estrogen-related nuclear receptor alpha	47	0	0	47
pregnane X nuclear receptor	40	0	0	40
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Bile salt export pump	0	60	0	60
Cyclin-dependent kinase 1	0	2	0	2
Heat shock protein HSP 90-beta	0	2	0	2
Xanthine dehydrogenase/oxidase	0	4	0	4
TAR DNA-binding protein 43	10	0	0	10
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	15	0	0	15
Ataxin-2	27	0	0	27
Carbonic anhydrase 1	0	11	0	15
Carbonic anhydrase 2	0	12	1	18
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	1	0	3
Glutamate receptor ionotropic, NMDA 1	0	9	1	13
Proton-coupled amino acid transporter 1	0	3	0	3
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	2
glp-1 receptor, partial	14	0	0	14
NPYLR7B	0	0	3	3
arylsulfatase A	28	0	0	28
thyroid stimulating hormone receptor	21	0	0	21
peripheral myelin protein 22	29	0	0	29
ATP-binding cassette sub-family C member 3	0	33	0	33
Multidrug resistance-associated protein 4	0	33	0	33
Beta-2 adrenergic receptor	0	8	7	16
Beta-1 adrenergic receptor	0	6	5	11
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
Beta-3 adrenergic receptor	0	5	4	9
Delta-type opioid receptor	0	4	1	5
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
Beta-2 adrenergic receptor	0	1	3	6
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Beta-2 adrenergic receptor	0	2	5	8
Canalicular multispecific organic anion transporter 1	0	32	0	32
Sex hormone-binding globulin	0	0	5	5
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	1	2	3
Androgen receptor	0	8	0	8
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
Guanine nucleotide-binding protein G	5	0	0	5
acetylcholinesterase	20	0	0	20
cytochrome P450 2D6	26	0	0	26
Spike glycoprotein	21	4	5	30
Chain A, Beta-lactamase	12	0	0	12
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
Gamma-aminobutyric acid receptor subunit rho-1	0	1	2	3
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
USP1 protein, partial	19	0	0	19
cytochrome P450 2D6 isoform 1	17	0	0	17
D(1A) dopamine receptor	24	0	0	24
atrial natriuretic peptide receptor 2 precursor	10	0	0	10
serine/threonine-protein kinase mTOR isoform 1	13	0	0	13
Solute carrier family 22 member 1	0	17	0	22
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	1	0	11
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	30	0	30
Albumin	0	0	8	8
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	21	0	21
Muscarinic acetylcholine receptor M2	0	19	5	28
Muscarinic acetylcholine receptor M4	0	17	3	23
Muscarinic acetylcholine receptor M1	0	15	3	23
Muscarinic acetylcholine receptor M3	0	13	3	20
Muscarinic acetylcholine receptor M4	0	14	2	20
5-hydroxytryptamine receptor 2C	0	11	2	13
Muscarinic acetylcholine receptor M5	0	14	2	20
Muscarinic acetylcholine receptor M5	0	16	3	22
Alpha-2A adrenergic receptor	0	30	6	38
Muscarinic acetylcholine receptor M2	0	15	3	23
Muscarinic acetylcholine receptor M1	0	20	6	30
Angiotensin-converting enzyme	0	17	0	17
D(2) dopamine receptor	0	31	2	36
5-hydroxytryptamine receptor 2A	0	11	2	13
Alpha-2B adrenergic receptor	0	26	3	31
Alpha-2C adrenergic receptor	0	26	6	34
5-hydroxytryptamine receptor 1A	0	28	3	32
Muscarinic acetylcholine receptor M3	0	17	4	24
D(1A) dopamine receptor	0	21	1	25
D(1B) dopamine receptor	0	5	0	7
UDP-glucuronosyltransferase 1A4	0	2	0	7
Histamine H2 receptor	0	13	2	15
Alpha-1D adrenergic receptor	0	25	5	31
5-hydroxytryptamine receptor 2A	0	30	1	31
5-hydroxytryptamine receptor 2C	0	31	1	32
5-hydroxytryptamine receptor 1B	0	23	1	24
5-hydroxytryptamine receptor 1D	0	6	1	7
5-hydroxytryptamine receptor 1F	0	6	1	7
5-hydroxytryptamine receptor 2B	0	11	2	13
5-hydroxytryptamine receptor 6	0	4	1	5
Histamine H1 receptor	0	8	1	9
Sodium-dependent serotonin transporter	0	28	0	28
5-hydroxytryptamine receptor 7	0	6	1	7
5-hydroxytryptamine receptor 5A	0	4	1	5
5-hydroxytryptamine receptor 5B	0	4	1	5
Histamine H1 receptor	0	23	2	25
D(3) dopamine receptor	0	24	1	28
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	6	0	7
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 3A	0	7	1	8
5-hydroxytryptamine receptor 2B	0	28	1	29
Histamine H2 receptor	17	3	2	26
D(1A) dopamine receptor	9	1	0	10
5-hydroxytryptamine receptor 6	0	20	1	21
5-hydroxytryptamine receptor 7	0	12	0	12
Voltage-dependent N-type calcium channel subunit alpha-1B	0	5	0	5
Sodium channel protein type 7 subunit alpha	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	19	0	19
Potassium voltage-gated channel subfamily H member 2	0	27	0	27
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	8	0	8
Sodium channel protein type 5 subunit alpha	0	8	0	8
Sodium channel protein type 9 subunit alpha	0	6	0	6
Sigma non-opioid intracellular receptor 1	0	5	2	7
5-hydroxytryptamine receptor 4	0	5	1	7
Nuclear receptor subfamily 3 group C member 3	0	16	0	16
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	25	1	26
5-hydroxytryptamine receptor 3B	0	7	1	8
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	4	0	4
Sodium channel protein type 8 subunit alpha	0	4	0	4
Histamine H3 receptor	0	5	2	7
Sodium channel protein type 10 subunit alpha	0	4	0	4
farnesoid X nuclear receptor	21	0	0	21
glucocerebrosidase	9	0	0	9
DNA polymerase kappa isoform 1	10	0	0	10
histone acetyltransferase KAT2A isoform 1	12	0	0	12
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	2	1	3
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
ATAD5 protein, partial	16	0	0	16
neuropeptide S receptor isoform A	8	0	0	8
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	8	0	0	8
EWS/FLI fusion protein	24	0	0	24
Rac1 protein	0	0	1	1
IDH1	17	0	0	17
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
lethal factor (plasmid)	13	0	0	13
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	8	0	8
Fatty acid-binding protein, liver	0	2	0	2
Integrin beta-3	8	1	0	9
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	4	1	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	8	1	0	9
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	6	0	6
Adenosine receptor A1	1	5	0	10
Adenosine receptor A2a	0	4	2	11
Substance-P receptor	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	11	1	1	13
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	18	12	4	34
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	7	1	8
Amine oxidase [flavin-containing] A	0	1	1	2
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	1	3	6
Muscarinic acetylcholine receptor M4	0	2	1	4
Reverse transcriptase/RNaseH	0	1	0	2
Muscarinic acetylcholine receptor	0	3	1	4
SMAD family member 2	7	0	0	7
Fumarate hydratase	12	0	0	12
SMAD family member 3	7	0	0	7
G	14	0	0	14
polyprotein	12	0	0	12
P53	2	0	0	2
peroxisome proliferator activated receptor gamma	31	0	0	31
aryl hydrocarbon receptor	19	0	0	19
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	12	0	0	12
thyroid hormone receptor beta isoform 2	38	0	0	38
survival motor neuron protein isoform d	17	0	0	17
cytochrome P450 3A4 isoform 1	18	0	0	18
muscleblind-like protein 1 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	18	11	3	32
Bile salt export pump	0	9	0	9
Interferon beta	19	0	0	19
HLA class I histocompatibility antigen, B alpha chain	14	0	0	14
Cellular tumor antigen p53	32	0	0	32
Gamma-aminobutyric acid receptor subunit beta-1	18	11	3	32
Gamma-aminobutyric acid receptor subunit delta	18	11	3	32
Gamma-aminobutyric acid receptor subunit gamma-2	18	11	4	33
Gamma-aminobutyric acid receptor subunit alpha-5	18	11	3	32
Gamma-aminobutyric acid receptor subunit alpha-3	18	11	3	32
Gamma-aminobutyric acid receptor subunit gamma-1	18	11	3	32
Gamma-aminobutyric acid receptor subunit alpha-2	18	11	3	32
Gamma-aminobutyric acid receptor subunit alpha-4	18	11	3	32
Gamma-aminobutyric acid receptor subunit gamma-3	18	11	3	32
Gamma-aminobutyric acid receptor subunit alpha-6	18	11	3	32
Gamma-aminobutyric acid receptor subunit beta-3	18	11	3	32
Gamma-aminobutyric acid receptor subunit beta-2	18	11	4	33
GABA theta subunit	18	11	3	32
Inositol hexakisphosphate kinase 1	14	0	0	14
Gamma-aminobutyric acid receptor subunit epsilon	18	11	3	32
Protein-arginine deiminase type-4	0	2	0	2
cytochrome P450 2C9, partial	14	0	0	14
cytochrome P450 2C19 precursor	13	0	0	13
pregnane X receptor	6	0	0	6
progesterone receptor	31	0	0	31
vitamin D (1,25- dihydroxyvitamin D3) receptor	25	0	0	25
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
galanin receptor type 3	0	2	0	2
Glucocorticoid receptor	0	12	1	15
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	2
PPM1D protein	6	0	0	6
caspase 7, apoptosis-related cysteine protease	13	0	0	13
estrogen receptor 2 (ER beta)	21	0	0	21
caspase-3	13	0	0	13
Caspase-7	8	0	0	8
caspase-3	8	0	0	8
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	2
Histone deacetylase 3	0	2	0	2
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	3	0	6
Prothrombin	0	2	1	3
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	1	0	4
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	3
Carbonic anhydrase 4	0	6	0	9
Carbonic anhydrase 6	0	4	0	7
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	2
Proteasome subunit alpha type-2	0	1	0	2
Proteasome subunit alpha type-3	0	1	0	2
Proteasome subunit alpha type-4	0	1	0	2
Proteasome subunit beta type-8	0	1	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	2
Proteasome subunit alpha type-5	0	1	0	2
Proteasome subunit beta type-4	0	1	0	2
Proteasome subunit beta type-6	0	1	0	2
Proteasome subunit beta type-5	0	5	0	7
Carbonic anhydrase 5A, mitochondrial	0	3	0	6
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	2
Carbonic anhydrase 7	0	3	0	6
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	2
Proteasome subunit beta type-2	0	1	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	2	4
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	2	0	2
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	5	1	9
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	2
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	1	0	2
Histone deacetylase 2	0	2	0	2
Proteasome subunit beta type-7	0	1	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	2	0	5
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Carbonic anhydrase 14	0	1	0	4
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
Angiotensin-converting enzyme	0	0	0	1
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	3	3
Cytochrome P450 2D6	0	10	1	11
15-lipoxygenase, partial	8	0	0	8
67.9K protein	10	0	0	10
mitogen-activated protein kinase 1	11	0	0	11
nuclear receptor ROR-gamma isoform 1	11	0	0	11
transient receptor potential cation channel subfamily V member 1	3	0	0	3
Transient receptor potential cation channel subfamily V member 1	0	4	1	5
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cytochrome P450 1A2	0	6	1	9
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Cannabinoid receptor 2	0	2	0	2
D(2) dopamine receptor	0	14	3	19
Inositol monophosphatase 1	11	0	0	11
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
GALC protein	8	0	0	8
thyrotropin-releasing hormone receptor	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-4	2	5	2	10
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-2	2	5	2	10
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Delta-type opioid receptor	0	5	0	7
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	5	2	8
Muscarinic acetylcholine receptor M3	0	0	2	5
Muscarinic acetylcholine receptor M2	0	0	1	5
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Vpr	5	0	0	5
Major prion protein	0	0	5	5
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	9	0	9
UDP-glucuronosyltransferase 2B7	0	3	0	6
Cytochrome P450 2B6	0	2	1	3
Cytochrome P450 2J2	0	8	0	8
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Prostaglandin E synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
DNA polymerase eta isoform 1	4	0	0	4
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	2	0	2
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	15	3	19
Delta-type opioid receptor	0	7	1	9
Kappa-type opioid receptor	0	15	1	17
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	2	0	2
Beta-secretase 1	0	2	1	3
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
streptokinase A precursor	0	0	1	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
Cytochrome P450 3A4	0	12	0	14
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	15	0	0	15
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	5	12
Translocator protein	0	4	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	7	4	11
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	6	5	11
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	4	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	3	9
Carbonic anhydrase	0	2	0	5
Chain A, Cruzipain	6	0	0	6
Rap guanine nucleotide exchange factor 4	2	0	0	2
NADPH oxidase 1	0	4	0	4
Snq2p	0	0	0	8
Adenylate cyclase type 1	0	3	0	3
Spike glycoprotein	0	4	5	9
Replicase polyprotein 1ab	0	5	5	10
vitamin D3 receptor isoform VDRA	12	0	0	12
histone deacetylase 9 isoform 3	6	0	0	6
ras-related protein Rab-9A	10	0	0	10
Transmembrane protease serine 2	0	4	5	9
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Potassium channel subfamily K member 2	0	3	2	5
Albumin	0	2	5	8
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	6	0	6
Procathepsin L	0	4	5	9
ATP-dependent translocase ABCB1	0	14	1	19
5-hydroxytryptamine receptor 1A	0	7	0	7
Replicase polyprotein 1a	0	4	5	9
Replicase polyprotein 1ab	0	4	5	9
Replicase polyprotein 1ab	0	8	5	13
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	2	5
Replicase polyprotein 1ab	0	10	5	15
Polyunsaturated fatty acid lipoxygenase ALOX15	0	8	0	8
Sphingomyelin phosphodiesterase	0	2	0	2
D	0	10	0	11
D(3) dopamine receptor	0	11	0	11
D(2) dopamine receptor	0	4	0	4
Substance-K receptor	0	6	0	6
D(4) dopamine receptor	0	12	1	16
Adenylate cyclase type 3	0	3	0	3
Sodium-dependent dopamine transporter	0	10	0	10
D(1B) dopamine receptor	0	9	0	9
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Trypanothione reductase	0	8	0	8
D(4) dopamine receptor	0	9	0	9
Histamine H1 receptor	0	2	2	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	8	0	16
5-hydroxytryptamine receptor 7	0	6	1	7
Adenylate cyclase type 8	0	3	0	3
Melanocortin receptor 3	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Calmodulin	0	1	4	5
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	8	1	12
Glutamate receptor ionotropic, NMDA 2B	0	8	1	12
Glutamate receptor ionotropic, NMDA 2C	0	8	1	13
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	5	0	5
Aldehyde oxidase	0	5	0	7
Glutamate receptor ionotropic, NMDA 2A	0	5	0	5
Glutamate receptor ionotropic, NMDA 2B	0	5	0	5
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	8	1	12
Adenylyl cyclase 7	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	8	1	12
D	0	2	0	2
Angiotensin-converting enzyme 2	0	4	5	9
Glutamate receptor ionotropic, NMDA 3A	0	8	1	12
Beta-1 adrenergic receptor	0	1	3	6
Alpha-1B adrenergic receptor	0	0	3	3
cytochrome P450 2C9 precursor	9	0	0	9
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	6	0	7
Alpha-1A adrenergic receptor	0	2	3	5
Amine oxidase [flavin-containing] A	0	8	0	9
Amine oxidase [flavin-containing] B	0	7	0	8
Adenosine receptor A2b	0	1	1	3
Alpha-2B adrenergic receptor	0	0	0	2
Alpha-1A adrenergic receptor	0	6	7	14
Alpha-1B adrenergic receptor	0	5	6	12
Mu-type opioid receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	0	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Solute carrier family 22 member 1	0	8	0	9
Multidrug and toxin extrusion protein 1	0	8	0	8
Nischarin	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Amyloid-beta precursor protein	1	2	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	5	2	7
Liver carboxylesterase 1	0	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
Sodium-dependent serotonin transporter	0	9	0	10
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	2	7
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	2	7
Sodium-dependent dopamine transporter	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
Transporter	0	7	1	9
dopamine D1 receptor	6	0	0	6
atrial natriuretic peptide receptor 1 precursor	6	0	0	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Rap guanine nucleotide exchange factor 3	5	0	0	5
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Neuraminidase	0	2	0	2
Parkin	4	0	0	4
pyruvate kinase	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	3	0	0	3
Aldo-keto reductase family 1 member B10	0	1	0	1
Transthyretin	0	3	1	5
Estrogen receptor	0	8	2	10
Aldehyde dehydrogenase, mitochondrial	0	2	0	2
Ornithine decarboxylase	3	0	0	3
Androgen receptor	0	1	0	3
Tyrosinase	0	2	0	2
Aromatase	0	2	0	2
Urease subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	6	0	7
Estrogen receptor	0	0	1	1
Urease subunit beta	0	2	0	2
Transporter	0	2	0	2
Substance-K receptor	0	2	0	2
Estrogen receptor beta	0	5	2	7
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	3	0	3
Prenyltransferase homolog	0	0	0	2
Estrogen receptor beta	0	0	1	1
huntingtin isoform 2	4	0	0	4
Solute carrier family 22 member 2	0	7	0	8
Solute carrier family 22 member 3	0	1	0	1
Histamine H3 receptor	0	1	0	2
Solute carrier family 22 member 2	0	6	0	7
Solute carrier family 22 member 4	0	1	0	1
Gamma-aminobutyric acid	0	1	1	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
PAX8	0	0	0	2
STAT3, partial	0	1	0	1
tumor necrosis factor	1	0	0	1
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
ATP-dependent translocase ABCB1	0	4	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	3	0	3
Solute carrier organic anion transporter family member 1B1	0	3	0	4
Multidrug and toxin extrusion protein 2	0	5	0	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Caspase-7	1	0	0	1
nonstructural protein 1	4	0	0	4
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
LacZ protein (plasmid)	0	0	1	1
beta-2 adrenergic receptor	4	0	0	4
type-1 angiotensin II receptor	0	1	0	1
perilipin-5	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
perilipin-1	0	1	0	1
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
apelin receptor	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	2	0	2
Fructose-1,6-bisphosphatase 1	0	1	0	1
Adenosine receptor A3	0	8	1	9
C-X-C chemokine receptor type 2	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
Caspase-1	0	1	0	1
Alpha-synuclein	2	2	0	4
C-C chemokine receptor type 2	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Monoglyceride lipase	0	1	0	1
Gasdermin-D	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
heat shock protein 90, putative	0	0	0	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Retinoic acid receptor RXR-alpha	0	0	3	3
Disintegrin and metalloproteinase domain-containing protein 17	3	1	0	4
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	1	0	1
galactokinase	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	0	0	1
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Polymerase acidic protein	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Heme oxygenase 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
72 kDa type IV collagenase	0	2	0	2
Hepatocyte growth factor receptor	0	2	0	2
Matrilysin	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Apoptosis regulator Bcl-2	0	2	0	2
Microtubule-associated protein tau	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
CPG DNA methylase	0	1	0	1
Lethal factor	0	1	0	1
Phosphoglycerate mutase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	2	0	2
Dipeptidyl peptidase 4	0	2	0	2
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
BH3-interacting domain death agonist	0	1	0	1
Lactoperoxidase	0	1	0	2
Bcl-2-like protein 1	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Bcl-2-related protein A1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	0	1
CREB-binding protein	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	0	2
Thromboxane-A synthase	0	2	0	2
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 5A	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	1	0	2
Cytochrome P450 2B1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Adenosine receptor A2a	0	7	3	11
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Mu-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	1	0	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	2	2
transcriptional regulator ERG isoform 3	3	0	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Histone deacetylase 7	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, Estrogen receptor 1 (alpha)	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
acid sphingomyelinase	1	0	0	1
BRCA1	1	0	0	1
Alpha-mannosidase	0	1	0	1
hexokinase-4 isoform 1	4	0	0	4
glucokinase regulatory protein	4	0	0	4
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	2	0	2
Steroid hormone receptor ERR2	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	0	1
Triosephosphate isomerase	0	1	0	1
Sialidase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
Ornithine decarboxylase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Protein kinase C alpha type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cruzipain	0	1	0	1
Adenosine receptor A1	0	4	1	7
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Acetylcholinesterase	0	2	0	2
Alpha-glucosidase MAL32	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Tyrosine-protein kinase CSK	0	1	0	1
Tyrosine-protein kinase ABL2	0	1	0	1
Tyrosine-protein kinase SYK	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 4	0	1	0	1
Quinone oxidoreductase	0	0	0	1
Cytoplasmic tyrosine-protein kinase BMX	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Oxysterols receptor LXR-beta	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
MO15-related protein kinase Pfmrk	0	1	0	1
Oxysterols receptor LXR-alpha	0	1	0	1
Tissue alpha-L-fucosidase	0	1	0	1
Integrase	0	2	0	2
Carboxylic ester hydrolase	0	2	0	3
Dipeptidyl peptidase 3	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Sialidase-2	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Cocaine esterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
UDP-glucuronosyltransferase 1A9	0	2	0	4
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Beta-2 adrenergic receptor	0	6	1	8
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Beta-3 adrenergic receptor	0	4	1	5
C-8 sterol isomerase	0	3	0	3
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	0	3
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	3
Macrophage migration inhibitory factor	0	3	0	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase	0	0	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 13	0	1	0	3
Histamine H4 receptor	0	2	2	4
Histamine H3 receptor	0	1	0	1
ClpP	2	0	0	2
Solute carrier family 22 member 8	0	2	0	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Sodium-dependent noradrenaline transporter	0	1	0	1
Cytochrome P450 2C19	0	4	0	5
D(2) dopamine receptor	0	1	0	1
Envelope glycoprotein	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	3	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	5
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	2	2
Beta-3 adrenergic receptor	0	0	1	1
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Oxytocin receptor	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	3
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Acetylcholinesterase	0	4	0	5
Cholinesterase	0	4	0	5
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Endochitinase	0	1	0	1
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Endochitinase A1	0	1	0	1
Acidic mammalian chitinase	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Polyphenol oxidase 2	0	0	0	3
Tyrosinase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
phosphoglycerate kinase	1	0	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
PINK1	1	0	0	1
5-hydroxytryptamine receptor 3E	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	2	3
5-hydroxytryptamine receptor 3D	0	1	1	2
5-hydroxytryptamine receptor 3C	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	3	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
Cholinesterase	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	3	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
bcl-2-related protein A1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	0	0	1
Solute carrier family 22 member 6	0	3	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Kappa-type opioid receptor	0	0	0	1
Cholinesterase	0	2	0	2
Muscarinic acetylcholine receptor M5	0	0	1	2
Cytochrome P450 2C8	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Membrane primary amine oxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
estrogen receptor beta isoform 1	0	2	0	2
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	2	0	2
POU domain, class 2, transcription factor 1	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 11	0	2	0	3
Solute carrier family 22 member 7	0	2	0	3
Chloroquine resistance transporter	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Renin	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Genome polyprotein	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Lysozyme C-1	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Protein kinase C alpha type	0	1	0	1
Beta-glucuronidase	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Protein kinase C eta type	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
WD repeat-containing protein 48	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
Protein kinase C theta type	0	1	0	1
guanine nucleotide-binding protein subunit alpha-15	0	1	1	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
D(3) dopamine receptor isoform e	1	0	0	1
trace amine-associated receptor 1	0	1	1	2
Phenylethanolamine N-methyltransferase	0	1	0	1
Dopamine beta-hydroxylase	0	0	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Carbonic anhydrase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (327)

Protein Targets (1,392)

Dysautonomia, Familial

Synonyms(1)

Research Excerpts

Overview

Research

Studies (327)

Drugs Studied (214)

Protein Targets (1,392)