An antidepressant whose molecular structure consists of four ring-like structures in a T-shape.
| Member | Definition | Role |
|---|
| demethylmirtazapine | A benzazepine metabolite resulting from demethylation of the antidpressant, mirtazapine. | N-demethylmirtazapine |
| dizocilpine | An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory. | dizocilpine |
| dizocilpine maleate | A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid. | dizocilpine maleate |
| mirtazapine | | mirtazapine |
| setiptiline | A tetracyclic antidepressant that is 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine carrying a methyl group at position 2. Its maleate salt is used for the treatment of depression in Japan. | setiptiline |