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phenazines
Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives.
ChEBI ID: 39201
Members (17)
| Member | Definition | Role |
|---|---|---|
| 1-hydroxyphenazine | A phenazine carrying a hydroxy substituent at the 1-position. | 1-hydroxyphenazine |
| 1-phenazinecarboxylic acid | An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group. | phenazine-1-carboxylic acid |
| 1,8-dimethoxyphenazine | 1,8-dimethoxyphenazine | |
| 2-hydroxyphenazine | 2-Hydroxyphenazine | |
| 4-bromo-N-(2-phenazinyl)benzamide | 4-bromo-N-(2-phenazinyl)benzamide | |
| 4-chloro-N-(2-methoxy-1-phenazinyl)benzamide | 4-chloro-N-(2-methoxy-1-phenazinyl)benzamide | |
| clofazimine | 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. | clofazimine |
| methanophenazine | methanophenazine | |
| methylphenazonium methosulfate | 5-methylphenazinium methyl sulfate | |
| N-(2-methylphenyl)-1-phenazinecarboxamide | N-(2-methylphenyl)-1-phenazinecarboxamide | |
| neutral red base | A member of the class of phenazines carrying methyl, amino and dimethylamino substituents at positions 2, 3 and 7 respectively. The free base of neutral red, which acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. | neutral red base |
| phenazine | An azaarene that is anthracene in which the carbon atoms at positions 9 and 10 are replaced by nitrogen atoms. | phenazine |
| phenazine-1-carboxamide | An aromatic amide that is phenazine substituted at C-1 with a carbamoyl group. | phenazine-1-carboxamide |
| Polycartine B | Polycartine B | |
| pyocyanine | An iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. An antibiotic pigment produced by Pseudomonas aeruginosa. | pyocyanine |
| saphenamycin | Saphenamycin | |
| Saphenic acid methyl ester | Saphenic acid methyl ester |
Research
Studies (2,648)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 688 (25.98) | 18.7374 |
| 1990's | 394 (14.88) | 18.2507 |
| 2000's | 389 (14.69) | 29.6817 |
| 2010's | 828 (31.27) | 24.3611 |
| 2020's | 349 (13.18) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 130 (4.33%) | 5.53% |
| Reviews | 162 (5.40%) | 6.00% |
| Case Studies | 300 (10.00%) | 4.05% |
| Observational | 12 (0.40%) | 0.25% |
| Other | 2,395 (79.86%) | 84.16% |