Any inhibitor of erythropoietin, a glycoprotein hormone that controls erythropoiesis (red blood cell production).
ChEBI ID: 91025
| Member | Definition | Class |
|---|---|---|
| resorcinol | A benzenediol that is benzene dihydroxylated at positions 1 and 3. | resorcinol |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 213 (30.78) | 18.7374 |
| 1990's | 73 (10.55) | 18.2507 |
| 2000's | 138 (19.94) | 29.6817 |
| 2010's | 220 (31.79) | 24.3611 |
| 2020's | 48 (6.94) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 3 (0.41%) | 5.53% |
| Reviews | 22 (3.00%) | 6.00% |
| Case Studies | 22 (3.00%) | 4.05% |
| Observational | 1 (0.14%) | 0.25% |
| Other | 685 (93.45%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 30.5375 | 4 | 5 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 42.0040 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 42.0040 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.3981 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 10.9640 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 0.3778 | 1 | 1 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 8.9082 | 1 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 0.0188 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 13.3359 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 33.3579 | 2 | 3 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 1.0000 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 50.1566 | 2 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 35.4813 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 47.1292 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 1.1883 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 26.5027 | 2 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 42.3894 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 6.4200 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 388.5429 | 6 | 21 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 278.2500 | 2 | 14 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 282.1857 | 2 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 278.4786 | 2 | 14 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 385.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 276.0714 | 6 | 21 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 377.2800 | 2 | 5 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 320.9286 | 2 | 14 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 333.9158 | 4 | 19 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 278.3357 | 2 | 14 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 278.2214 | 2 | 14 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 308.9333 | 3 | 15 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 323.7143 | 2 | 14 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 282.6929 | 2 | 14 |
| Chain A, Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 7.7000 | 1 | 3 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 1,072.3333 | 3 | 3 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 10,200.0000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 3,000.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Chain A, Bacterial regulatory proteins, tetR family | Corynebacterium glutamicum ATCC 13032 | Kd | 0.1900 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | Kd | 86.9000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Polyphenol oxidase 2 | Agaricus bisporus | ID50 | 1,200.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | Km | 460.0000 | 1 | 1 |