A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Reference |
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| "Hypothyroidism is easily treated with T4." | ( Morrow, LB, 1978) |
| "response in hypothyroidism is significantly correlated with both T3 and T4 levels, suggesting suppression of this inhibitory pathway in increasingly severe hypothyroidism." | ( Hall, R; Heath, M; Mora, B; Scanlon, MF; Shale, DJ; Snow, MH; Weightman, DR, 1977) |
| "Hypothyroidism is induced in rats treated with thiamazole, an antithyroid drug." | ( Faucounau, N; Maraud, R; Stoll, R, 1978) |
| "Hypothyroidism is a common finding in cystinosis, and it is suggested that thyroxine treatment be started when the TSH concentration becomes raised." | ( Burke, JR; Chantler, C; El-Bishti, MM; Maisey, MN, 1978) |
| "Compensated hypothyroidism is frequent in cystinosis and may be one factor in the severe growth retardation in this condition." | ( Broyer, M; Czernichow, P; Lenoir, G; Rappaport, R; Roy, MP, 1978) |
| "The hypothyroidism is probably a consequence of impaired thyroidal elaboration of thyroid hormone, as well as decreased peripheral conversion of T4 to T3." | ( Cohlmia, JB; Grantham, JJ; Meek, JC; Whittier, FC, 1975) |
| "Hypothyroidism is listed as a possible cause of hypercalcemia." | ( Jones, TC; Yium, JJ, 1977) |
| "Subclinical hypothyroidism is an example of the impact of technology on the concept of a disease." | ( Levin, K; Nilsson, G; Nordlander, S, 1976) |
| "-- When hypothyroidism is suspected in newborns or infants no protracted diagnostic procedures are justified with respect to brain development and its requirement of thyroid hormone during this period of life." | ( Kuhn, N; Stahnke, N; Wiebel, J; Willig, RP, 1976) |
| "Changes in hypothyroidism are in good agreement with changes of blood glucose and insulinemia, as described previously." | ( Felt, V; Havelka, J; Nedvédková, J; Nĕmec, J; Zamrazil, V, 1976) |
| "Only in (primary) hypothyroidism is the triiodothyronine estimation diagnostically less important than the T4-test." | ( Ehret, G; Gehring, D; Hoffman, G; Thiele, S, 1975) |
| "Central hypothyroidism is an uncommon condition characterized by insufficient thyroid gland stimulation by TSH, owing to hypothalamic and/or pituitary dysfunction." | ( Ridgway, EC; Samuels, MH, 1992) |
| "Hypothyroidism is associated with abnormalities in renal water handling, which include a delay in excretion of an acute water load, decreased urinary concentrating ability, and increased urine volume." | ( Howard, RL; Kim, JK; Rossi, N; Schrier, RW; Summer, S, 1992) |
| "Subclinical hypothyroidism is found in about 7." | ( Althaus, BU; Burckhardt, D; Engler, H; Girard, J; Marquardt, K; Ryff, AS; Staub, JJ; Trabucco, P; Weintraub, BD, 1992) |
| "For example, hypothyroidism is associated with the development of a marked synergism between alpha 1- and beta-adrenergic pathways to stimulate type II iodothyronine 5'-deiodinase activity." | ( Larsen, PR; Moolten, N; Noronha, M; Raasmaja, A, 1991) |
| "Hypothyroidism is a reversible cause for dementia." | ( Granger, CV; Smith, CL, 1992) |
| "Primary hypothyroidism is a presumptive proximate basis for increased serum PRL concentrations." | ( Iranmanesh, A; Lizarralde, G; Veldhuis, JD, 1992) |
| "Hypothyroidism is a cause of secondary hyperlipidaemia." | ( Ball, MJ; Griffiths, D; Thorogood, M, 1991) |
| "Hypothyroidism is associated with a decreased tyrosine hydroxylase activation between 4 and 50 days, as compared to controls and hyperthyroidism with an increased activation between 6 and 30 days." | ( Bagayoko, A; Blouquit, MF; Gripois, D; Valens, M, 1990) |
| "Hypothyroidism is not commonly considered a complication of radiotherapy for head and neck cancer." | ( Blakeslee, DB; Duncan, NO; Liening, DA; Smith, DB, 1990) |
| "Lithium-induced hypothyroidism is likely to be related to the length of treatment." | ( Antonangeli, L; Bartalena, L; Bogazzi, F; Dell'Osso, L; Meschi, M; Pellegrini, L; Pinchera, A; Placidi, GF, 1990) |
| "Hypothyroidism is associated with a severe retardation of body growth, which appears more marked in thyroidectomized than in MMI treated rats; no significant variations in testis weight are observed." | ( Andó, S; Beraldi, E; Fugassa, E; Palmero, S; Panno, ML; Prati, M; Salerno, M; Tarantino, G, 1990) |
| "A case of juvenile hypothyroidism is presented showing evidence of delayed shedding of deciduous teeth, root development, eruption of permanent teeth as well as retarded skeletal growth." | ( Chindia, ML; Mg'ang'a, PM, 1990) |
| "Hypothyroidism is a major cause of secondary hypercholesterolemia." | ( Bagchi, N; Brown, TR; Jackson, K; Kasim, SE; Khilnani, S; Lehmann, MH; Steinman, RT, 1990) |
| "Congenital hypothyroidism is a preventable cause of mental retardation." | ( Akber, M; Khurshid, M; Lakhani, M; Naqvi, SH, 1989) |
| "Hypothyroidism is gratifying to treat, since the response to hormone replacement therapy is excellent." | ( Miller, JL; Rose, LI; Salman, K, 1989) |
| "Thus, hypothyroidism is characterized by decreased circulating levels of ANP which are reversed by L-T4 therapy." | ( Burnett, JC; Gharib, H; Heublein, D; Zimmerman, D; Zimmerman, RS, 1987) |
| "Hypothyroidism is associated with an enhanced sensitivity of rat fat cells to the inhibitory action of adenosine and adenosine agonists." | ( Malbon, CC; Mangano, TJ; Rapiejko, PJ, 1985) |
| "Subclinical hypothyroidism is common among middle-aged and old women, and our findings indicate that approximately one woman in four with this 'subclinical' condition will benefit from L-thyroxine treatment." | ( Caidahl, K; Fager, G; Lindstedt, G; Lundberg, PA; Nyström, E; Wikkelsö, C, 1988) |
| "Congenital hypothyroidism is a common but preventable cause of mental retardation." | ( Abdallah, A; Postellon, DC, 1986) |
| "The treatment of hypothyroidism is much easier to adapt using the TSH test." | ( Duet, M; Lajeunie, E; Lubetzki, J; Sidibe, EH, 1987) |
| "Congenital hypothyroidism is a relatively common endocrine disorder, affecting one in 4000 newborn infants." | ( LaFranchi, S, 1987) |
| "Hypothyroidism is produced with daily injection of mercazolil (6 mg/kg) 3 weeks before the operation and during the time of the experiment." | ( Antipanova, EM; Pavlov, AV; Zapriagaev, VV, 1988) |
| "The severity of hypothyroidism is closely related to the titer of microsomal antibody, especially the immunoglobulin G1 subclass of microsomal antibody, and partly predictable from the titer in early pregnancy." | ( Jansson, R, 1986) |
| "Pseudohypothyroidism is a prevalent "non-disease" that represents an erroneous diagnosis of hypothyroidism." | ( Schneeberg, NG, 1986) |
| "Although hypothyroidism is known to produce secondary amenorrhea, hyperprolactinemia, and pituitary enlargement, this is believed to be the first computed tomographic documentation of such a "pseudoprolactinoma" presenting as primary amenorrhea." | ( Garber, J; Kleefield, J; Poretsky, L, 1986) |
| "Hypothyroidism is not commonly associated with acanthosis nigricans (AN)." | ( Dix, JH; Fuenning, C; Levy, WJ, 1986) |
| "Hypothyroidism is generally observed in patients with autoimmune thyroiditis." | ( Fragu, P; Schlumberger, M, 1985) |
| "Hypothyroidism is a clinical entity first defined almost 100 years ago; it is caused, for the most part, by an autoimmune disorder or treatment of previous hyperthyroidism and so the vast majority have primary hypothyroidism." | ( Sawin, CT, 1985) |
| "3) Congenital hypothyroidism is not associated with abnormal somatotroph cell responses to TRH." | ( Amado, O; Sack, J; Shafrir, Y; Urbach, D, 1985) |
| "Generally speaking, hypothyroidism is not to be regarded as a complication of radioiodine treatment for hyperthyroidism, but as its natural end result." | ( Eriksson, E; Eriksson, K; Wahlberg, P, 1985) |
| "Neonatal hypothyroidism is known to induce the accumulation of substance P and serotonin in many discrete brain nuclei of the rat." | ( Dupont, A; Mérand, Y; Savard, P, 1984) |
| "Hypothyroidism is a frequently diagnosed endocrine disorder that has characteristic clinical signs and symptoms." | ( Klein, I; Levey, GS, 1984) |
| "An hypothyroidism is discovered." | ( Ferrand, P; Heim, J, 1982) |
| "Acquired hypothyroidism is also associated with a decreased density of alpha 1- and beta-adrenergic receptors in rat myocardium." | ( Noguchi, A; Whitsett, JA, 1982) |
| "When hypothyroidism is induced surgically in early steps of development in the rat, an increase in serum aldosterone concentration (AC), in absence of changes in plasma renin activity (PRA), is observed." | ( Jiménez, E; Montiel, M; Morell, M; Narváez, JA; Ruiz, M, 1984) |
| "Hypothyroidism is frequently associated with abnormal sexual development." | ( Huseman, CA; Kugler, JA, 1983) |
| "Hypothyroidism is associated with hypercholesterolemia and increased risk for atherosclerotic disease." | ( Beaubatie, L; Catanzano, G; Laplaud, PM; Maurel, D, 1984) |
| "Hypothyroidism is known to affect calcium homeostasis by decreasing bone turnover and serum calcium level, and by increasing parathyroid hormone and 1,25-dihydroxyvitamin D concentrations." | ( Eil, C; O'Brian, JT; Zaloga, GP, 1984) |
| "Hypothyroidism is associated with changes in renal function and a decrease in kidney weight." | ( Davis, RG; Fregly, MJ; Madsen, KM; Tisher, CC, 1983) |
| "Indeed neonatal hypothyroidism is known to result in end-organ subsensitivity and the norepinephrine turnover rate, an index of spontaneous activity of the neuron, was found to be markedly subnormal." | ( Slepetis, RJ; Slotkin, TA, 1984) |
| "Moderate hypothyroidism is frequently present in pseudohypoparathyroidism." | ( Stögmann, W, 1981) |
| "If hypothyroidism is associated with cardiovascular disease, other debilitating illness, or advanced age, thyroxine must be given with extreme caution in order to avoid dangerous tachyarrhythmias or too rapid acceleration of the metabolic rate." | ( Hellman, DE, 1980) |
| "An hypothyroidism is discovered." | ( Ferrand, P; Heim, J, 1981) |
| "The hypothyroidism is attributed to the influence of the drug on hypothalamus-pituitary function and the secretion of hormones responsible for the thyroid metabolism." | ( Bhup, R; Dhindsa, KS; Omran, RG, 1981) |
| "Screening for Hypothyroidism is part of the Austrian Newborn Screening for Inborn Errors and centralized (ca." | ( Thalhammer, O, 1981) |
| "Subclinical hypothyroidism is associated not only with elevated LDL-cholesterol levels and low HDL-cholesterol levels but also with elevated lipoprotein (a)." | ( Janus, ED; Kung, AW; Pang, RW, 1995) |
| "In both tissues, hypothyroidism is associated with a marked reduction in the capacity to generate cAMP, but this is not completely restored even after 2 days of a receptor-saturating dose of T3." | ( Raasmaja, A; Rubio, A; Silva, JE, 1995) |
| "Hypothyroidism is known to be associated with abnormalities of kidney function; recently, low atrial natriuretic peptide (ANP) plasma levels have been reported." | ( Barna, I; Büki, B; De Châtel, R; Földes, J; Lang, RE; Tóth, M, 1994) |
| "Hypothyroidism is a common disorder, easily treated with thyroxine therapy." | ( De Whalley, P, 1995) |
| "Hypothyroidism is a common condition that is frequently irreversible and requires lifelong thyroid replacement therapy." | ( Comtois, R; Faucher, L; Laflèche, L, 1995) |
| "Hypothyroidism is a well known cause of secondary hyperlipidemia, which mainly affects low density lipoprotein (LDL) cholesterol levels, but the result on the effects of L-T4 replacement therapy on the Lp(a) concentration is controversial." | ( Alvarez, JJ; Lasunción, MA; Pazos, F; Rubiés-Prat, J; Varela, C, 1995) |
| "Congenital hypothyroidism is a frequently occurring condition with possibly severe and irreversible consequences." | ( Aloj, SM; Gentile, F, 1994) |
| "Since overt hypothyroidism is often associated with infertility, it is uncommon in pregnancy." | ( , 1993) |
| "Hypothyroidism is known to decrease cerebral metabolism." | ( Crosby, N; Hemmings, S; Ijaz, S; Kalra, J; Mazagri, R; Senthilsvlvan, A; Shuaib, A, 1994) |
| "Hypothyroidism is a common cause of rhabomyolysis and hyper-cholesterolaemia and its association with lipid lowering drugs is an additional risk factor for rhabdomyolysis." | ( Gouton, M, 1993) |
| "Since hypothyroidism is associated with decreased expression of Na,K-ATPase alpha 1, alpha 2 and beta 1 subunits in heart and alpha 2 subunit in skeletal muscle, we aimed to test the hypothesis that chronic in vivo administration of amiodarone would result in changes in the expression of Na,K-ATPase isoforms that resembled those seen in hypothyroid rat." | ( Bersohn, MM; Hensley, CB; McDonough, AA; Sarma, JS; Singh, BN, 1994) |
| "Primary hypothyroidism is commonly associated with lethargy, alopecia, hyperpigmentation, alterations in skin and hair coat, anestrus and bradycardia." | ( Glaus, T; Jaggy, A; Tipold, A, 1994) |
| "Hypothyroidism is among the most frequent causes of reversible dementias." | ( Haupt, M; Kurz, A, 1993) |
| "Hypothyroidism is a possible predisposing factor in a number of disorders of companion psittacine birds." | ( Baier, JG; Bruyette, DS; Carpenter, JW; Galland, J; Harms, CA; Hoskinson, JJ; Veatch, JK; Wilson, SC, 1994) |
| "Hypothyroidism is known to lead to a certain degree of functional insufficiency of the adrenal gland by affecting both the hypophyseal axis and peripheral metabolism of cortisol." | ( Bakiri, F; Benmiloud, M, 1994) |
| "Amiodarone-induced hypothyroidism is treated with levothyroxine and hyperthyroidism with antithyroid drugs." | ( Jaffe, CA; Khanderia, U; Theisen, V, 1993) |
| "Hypothyroidism is a common disorder and while the association of overt hypothyroidism with hypercholesterolaemia is clear, the effect upon lipids of the minor abnormalities of thyroid function often found in those receiving T4 replacement therapy is unclear." | ( Betteridge, J; Daykin, J; Franklyn, JA; Holder, R; Hughes, EA; Jones, SR; Sheppard, MC, 1993) |
| "Hyperthyroidism and hypothyroidism are common disorders in the elderly and may remain unrecognised until a patient presents with an apparently unrelated problem." | ( Stockigt, JR, 1993) |
| "Early diagnosis of hypothyroidism is dependent on proper timing and collection of blood samples and an efficient screening program reporting accurate results." | ( Miculan, J; Paes, BA; Turner, S, 1993) |
| "Hypothyroidism is the condition most commonly treated with exogenous thyroid hormone." | ( Kaplan, MM, 1993) |
| ""Subclinical hypothyroidism" is not always a forerunner of primary hypothyroidism." | ( Kabadi, UM, 1993) |
| "Frank hypothyroidism is known to induce neurological and mental dysfunction." | ( Baschieri, L; Caraccio, N; Del Guerra, P; Luisi, M; Monzani, F; Pruneti, CA; Pucci, E, 1993) |
| "We conclude that hypothyroidism is common in peritoneal dialysis patients, usually antedates dialysis therapy, results in lower serum albumin and creatinine concentrations and higher serum triglyceride concentrations, is associated with lower serum PTH concentrations, and that thyroid function surveillance is not necessary in the absence of symptoms suggestive of hypothyroidism." | ( Bello, MJ; Cruz, C; Dumler, F; Gotaas, KA; Macks, H, 1995) |
| "Hypothyroidism is associated with both reduced central 5-HT function and an increased incidence of depression." | ( Chambers, SM; Cleare, AJ; Dawling, S; McGregor, A; O'Keane, V, 1996) |
| "Hypothyroidism is associated with inhibition of hepatic oxidative metabolism of many drugs." | ( Sarich, TC; Wright, JM, 1996) |
| "While foetal hypothyroidism is at present unavoidable, earlier diagnosis and initiation of treatment in neonates with CH are important and highly recommended." | ( Bargagna, S; Chiovato, L; Dinetti, D; Giachetti, C; Marcheschi, M; Montanelli, L; Pinchera, A; Romolini, E, 1997) |
| "Subclinical hypothyroidism is a frequent disorder in populations and has been shown to be a risk factor for coronary heart disease (CHD)." | ( Gündoğan, MA; Kilinç, C; Kutluay, T; Ozata, M; Yildirimkaya, M; Yilmaz, K, 1996) |
| "Patients with hypothyroidism are considered to have an increased risk of developing atherosclerosis; because endothelial dysfunction is an early sign of atherosclerosis, we investigated whether endothelial dysfunction is present in patients with hypothyroidism." | ( Alevizaki, M; Koutras, DA; Lekakis, J; Mantzos, J; Marafelia, P; Papamichael, C; Piperingos, G; Stamatelopoulos, S, 1997) |
| "Congenital hypothyroidism is very rare compared to primary hypothyroidism." | ( de Parscau, L; Giroux, B; Giroux, JD; Metz, C, 1997) |
| "Hypothyroidism is frequently associated with hypercholesterolemia and an increased risk for atherosclerosis, whereas hyperthyroidism is known to precipitate angina or myocardial infarction in patients with underlying coronary heart disease." | ( Falko, JM; Hanna, AN; Koneru, L; Newman, HA; Sundaram, V, 1997) |
| "Hypothyroidism is a relative state, long associated with fatigue and depression." | ( Dzurec, LC, 1997) |
| "Hypothyroidism is a commonly diagnosed endocrine disorder." | ( Westphal, SA, 1997) |
| "Hypothyroidism is a recognised complication of GH therapy in GH deficient children." | ( Frisch, H; Heimann, G; Kim, C; Lebl, J; Martinez, R; Otten, B; Pfäffle, RW, 1997) |
| "Central hypothyroidism is often the presenting feature of combined pituitary hormone deficiency (CPHD), but it is not detected in screening programs that rely upon elevation of TSH." | ( Adess, ME; Brown, MR; Hurley, DL; Parks, JS; Rich, BH; Rosenthal, IM; VanderHeyden, TC; Voss, TC, 1998) |
| "Thus, hypothyroidism is likely to have important physiological consequences under circumstances in which KATP channels are activated, such as during ischemia." | ( French, RJ; Giles, W; Harbison, S; Light, P; Shimoni, Y, 1998) |
| "Hypothyroidism is associated with a reduction in GH pulsatility and in GH-response to stimulatory tests." | ( Boccardo, G; Bona, G; Chiorboli, E; Rapa, A; Silvestro, L, 1998) |
| "Hypothyroidism is associated with an increase in total cholesterol, triglycerides, HDL-C, apolipoprotein A-I and B-100, and Lp(a)." | ( Hernández-Mijares, A; Lluch, I; Lorente, D; Martínez-Triguero, ML; Molina, E; Morillas, C; Muñoz, ML; Nguyen, TT; Peña, H, 1998) |
| "Hypothyroidism is a clinical entity resulting from deficiency of thyroid hormones or, more rarely, from their impaired activity at tissue level." | ( Hallengren, B, 1998) |
| "Overt hypothyroidism is known to be associated with increased serum creatine kinase (CK) levels." | ( Beyer, IW; Cogan, E; Demeester-Mirkine, N; Fuss, MJ; Karmali, R, 1998) |
| "Central hypothyroidism is rare and is often associated with other pituitary deficiencies as it is generally encountered in case of hypothalamo-pituitary tumoral process." | ( Chanson, P, 1998) |
| "Patients with hypothyroidism are usually treated with thyroxine (levothyroxine) only, although both thyroxine and triiodothyronine are secreted by the normal thyroid gland." | ( Bunevicius, R; Kazanavicius, G; Prange, AJ; Zalinkevicius, R, 1999) |
| "Hypothyroidism is widely accepted as a cause of hyponatremia and hypercreatininemia." | ( Baajafer, FS; Hammami, MM; Mohamed, GE, 1999) |
| "Hypothyroidism is an endocrine condition found in elderly patients that is often confused with normal changes associated with aging." | ( Bailes, BK, 1999) |
| "Subclinical hypothyroidism is a common disorder with a prevalence of about 7 to 8% in women (most frequently in females over 50 years), and about 3% in men." | ( Lerch, M; Meier, C; Staub, JJ, 1999) |
| "Congenital hypothyroidism is a common preventable cause of mental retardation." | ( LaFranchi, S, 1999) |
| "Hypothyroidism is more common (two out of three cases) than hyperthyroidism (one out of three cases)." | ( Bailly, F; Broussolle, C; Steineur, MP; Trépo, C; Zoulim, F, 1999) |
| "Subclinical hypothyroidism is a condition characterized by increased levels of thyroid-stimulating hormone (TSH) associated with normal levels of free triiodothyronine (FT3) and free thyroxine (FT4)." | ( Cerutti, R; Colombo, R; Dionisio, P; Grossi, E; Miano, G; Rivolta, G, 1999) |
| "Central hypothyroidism is one of the limitations of the use of sensitive TSH assays as first line screen in evaluating thyroid function." | ( Bakiri, F, 1999) |
| "Hypothyroidism is possibly also associated with an increased risk for coronary artery disease, which may be related to atherogenic changes in lipid profile." | ( Catargi, B; Cochet, C; Ducassou, D; Parrot-Roulaud, F; Roger, P; Tabarin, A, 1999) |
| "Hypothyroidism is associated with increased cardiovascular morbidity, which cannot be fully explained by the atherogenic lipid profile observed in these patients." | ( Aakvaag, A; Lien, EA; Nedrebø, BG; Nygård, O; Ueland, PM; Varhaug, JE, 2000) |
| "Hypothyroidism is associated with abnormalities in lipid metabolism but its effect on LDL size is not known." | ( Lupattelli, G; Mannarino, E; Pagliaricci, S; Pirro, M; Roscini, AR; Siepi, D, 1999) |
| "Hypothyroidism is a common endocrine disorder affecting 1." | ( Elliott, B, 2000) |
| "Hypothyroidism is the most frequent dysfunction but hyperthyroidism is also associated to Down syndrome." | ( Sanz, J, 1999) |
| "Drug induced hypothyroidism is known to occur with several medications." | ( Caley, CF; Feret, BM, 2000) |
| "When hypothyroidism is detected in a patient with suspected dementia, thyroxin should be tried first of all." | ( Fylkesnes, SI; Nygaard, HA, 2000) |
| "Hypothyroidism is associated with a reduction in GH pulsatility and in GH-response to stimulatory tests." | ( Boccardo, G; Bona, G; Chiorboli, E; Rapa, A; Silvestro, L, 1999) |
| "Subclinical hypothyroidism is associated with changes in videodensitometric myocardial structure." | ( Bertini, A; Caraccio, N; Di Bello, V; Ferrannini, E; Giorgi, D; Giusti, C; Monzani, F; Paterni, M; Talini, E; Valenti, G, 2000) |
| "Though hypothyroidism is inevitable side effect after the therapy (replacement therapy is needed) generally proposed doses of I131 should not be limited to avoid low efficacy of the treatment." | ( Gawryś, G; Sztuka-Pietkiewicz, A; Tuchendler, R; Zdrojewicz, Z, 2000) |
| "In conclusion, hypothyroidism is associated with major depressive symptoms." | ( Eriksson, M; Gunnarsson, T; Nordin, C; Sjöberg, S, 2001) |
| "Hypothyroidism is not rare in aged people." | ( Hashizume, K, 2000) |
| "If the hypothyroidism is apparent prior to pregnancy, it should be corrected before conception (target TSH value of 1 mU/l)." | ( Boer, K; Corssmit, EP; Prummel, MF; Wiersinga, WM, 2001) |
| "The hypothyroidism is transient and thyroid function returns to normal in 2 to 3 weeks after iodide withdrawal, but transient T4 replacement therapy may be required in some patients." | ( Georgopoulos, N; Kyriazopoulou, V; Markou, K; Vagenakis, AG, 2001) |
| "The incidence of hypothyroidism is higher among children with Down syndrome than among children in the general population." | ( Arata-Bellabarba, G; Arias, A; Delgado, MC; Jiménez-López, V; Paoli, M; Vivas, E, 2001) |
| "Hypothyroidism is induced in male adult rats by giving 0." | ( Chainy, GB; Das, K, 2001) |
| "Primary hypothyroidism is a common sequela of craniospinal radiotherapy in the treatment of childhood medulloblastoma." | ( Besenzon, L; Corrias, A; di Montezemolo, LC; Einaudi, S; Genitori, L; Madon, E; Ricardi, U; Sandri, A; Urgesi, A, 2001) |
| "Hypothyroidism is often associated with defective memory, psychomotor slowing, and depression." | ( Bol, A; Constant, EL; Cosnard, G; Daumerie, C; de Volder, AG; Ivanoiu, A; Labar, D; Melin, J; Seghers, A, 2001) |
| "Primary hypothyroidism is common in the elderly." | ( Benoit, P; Boeglin, MB; Roche, B; Tauveron, I; Thieblot, P; Yazbeck, R, 2001) |
| "Primary hypothyroidism is still lately discovered in the elderly." | ( Benoit, P; Boeglin, MB; Roche, B; Tauveron, I; Thieblot, P; Yazbeck, R, 2001) |
| "Drug-induced hypothyroidism is an infrequent side effect of therapy with PAS, and only a few cases of PAS-induced hypothyroidism have been reported so far." | ( Horiba, M; Kimura, T; Mizutani, H; Shindoh, J; Son, M; Wakahara, K, 2001) |
| "Hypothyroidism is recognized as a common complication of treatment in patients with head and neck carcinoma (HNC) and is reported in up to 75% of patients who receive combined treatment." | ( Bedrin, L; Dori, S; Horowitz, Z; Kronenberg, J; Mini, S; Peleg, M; Shoshani, Y; Taicher, S; Talmi, YP; Wolf, M, 2001) |
| "Hypothyroidism is common in the renal failure population and is both influenced by the onset of renal failure and its correction with renal transplantation." | ( Mathew, TH; Russ, GR; Thomas, MC, 2002) |
| "Hypothyroidism is frequently accompanied by cardiac dysfunction, increased vascular resistance, and a greater prevalence of hypertension." | ( Dernellis, J; Panaretou, M, 2002) |
| "Secondary hypothyroidism is extremely rare." | ( Basaria, S; Braga, M, 2002) |
| "Symptoms of hypothyroidism are often unspecific and numerous." | ( Norheim, I; Thorsby, A, 2002) |
| "Hypothyroidism is a common disease with a prevalence of 5-6% in women and 1-2% in men." | ( Haug, E, 2002) |
| "Hypothyroidism is associated with atherosclerotic events, however, the mechanism is unclear." | ( Ercan, M; Hatemi, H; Konukoglu, D, 2002) |
| "Hypothyroidism is associated with cardiovascular dysfunction." | ( Davies, JS; Evans, LM; John, R; Lazarus, JH; Obuobie, K; Smith, J, 2002) |
| "Hypothyroidism is very often associated with cardiovascular diseases and neurological complications." | ( Bicíková, M; Hampl, R; Hill, M; Stanická, S; Tallová, J; Vondra, K, 2002) |
| "Infraclinical hypothyroidism is a recognized entity defined in terms of laboratory results which occurs more readily in women." | ( de Talancé, N; Fournier, B; Giordanella, JP; Spyckerelle, Y; Steinmetz, J, 2002) |
| "Hypothyroidism is associated with premature atherosclerosis and cardiovascular disease." | ( Christ-Crain, M; Guglielmetti, M; Huber, PR; Meier, C; Müller, B; Riesen, W; Staub, JJ, 2003) |
| "Hypothyroidism is associated with significant abnormalities in the renal handling of salt and water." | ( Bachmann, S; Ellison, DH; Kahl, T; Klussmann, E; Schmitt, R, 2003) |
| "Primary hypothyroidism is a chronic and insidious disease caused by failure of thyroid hormone production." | ( Baldini, V; Mastropasqua, M; Paggi, A; Spagna, G; Tedesco, I, 2003) |
| "Hypothyroidism is a rare cause of rhabdomyolysis, but should always be considered in a patient with an unexplained increase in creatine kinase concentrations." | ( Barahona, MJ; Mauri, A; Paredes, R; Sucunza, N; Wägner, AM, 2002) |
| "Central hypothyroidism is an exceedingly rare form of hypothyroidism that results from a variety of conditions affecting the hypothalamus and the pituitary gland." | ( Altman, K; Basaria, S; Braga-Basaria, M, 2003) |
| "Primary hypothyroidism is known to be associated with a consistent elevation in serum creatinine levels." | ( del-Río Camacho, G; Hortas Nieto, ML; Picazo Angelín, B; Romero González, J; Ruiz Moreno, JA; Tapia Ceballos, L, 2003) |
| "The hypothyroidism is a frequent endocrinopathos." | ( Ben Amar, H; Ben Slimen, M; Hachicha, M; Kolsi, S; Loulou, F; Mahfoudh, A; Rekik, S; Triki, A, 2002) |
| "Hypothyroidism is associated with a number of abnormalities in lipoprotein metabolism." | ( Adamczewski, Z; de Barros, JP; Dedecjus, M; Gambert, P; Gautier, T; Lagrost, L; Lewinski, A; Masson, D; Moulin, P, 2003) |
| "Early transient hypothyroidism is common in SAT." | ( Aniszewski, JP; Atkinson, EJ; Fatourechi, GZ; Fatourechi, V; Jacobsen, SJ, 2003) |
| "Canine hypothyroidism is a rather rare endocrine disorder in Switzerland." | ( Boretti, FS; Breyer-Haube, I; Kaspers, B; Reusch, CE, 2003) |
| "Hypothyroidism is associated with impaired blood flow to skeletal muscle under whole body exercise conditions." | ( Bausch, L; McAllister, RM, 2003) |
| "Hypothyroidism is associated with intrinsic myocardial changes reflected by alterations in contractility and relaxation." | ( Brenta, G; Fretes, O; Matute, ML; Mutti, LA; Perrone, A; Schnitman, M, 2003) |
| "Congenital hypothyroidism is one of the most frequent endocrine diseases of the newborn and requires an early diagnosis to avoid its deleterious effects on neurological and intellectual functions." | ( Arnello, F; Becerra, C; Brantes, J; Bruggendieck, B; Bustos, ME; Donoso, G; Jiménez, C; Ladrón de Guevara, D; Lobo, G; Pérez, A; Vivanco, X, 2003) |
| "Chronic hypothyroidism is frequently associated with atherosclerosis due to increased cholesterol plasma levels; nevertheless, the contribution of impaired reverse cholesterol transport (RCT) in this process has not been completely elucidated." | ( Castro, G; Franco, M; Huesca-Gómez, C; Medina, A; Montaño, LF; Pérez-Méndez, O; Posadas-Romero, C; Ramírez, S; Regalado, JC; Romero, L, 2003) |
| "Subclinical hypothyroidism is associated with aspecific complaints such as tiredness, cognitive and depressive complaints, subtle disturbances in lipid values, an increased risk of cardiovascular disease, ovulatory dysfunction and a negative effect on foetal psychomotor development and pregnancy outcome." | ( Corssmit, EP; Wiersinga, WM, 2003) |
| "Subclinical hypothyroidism is more common than HO and is most prevalent in the elderly, particularly in women." | ( Davis, JD; Flashman, LA; Stern, RA, 2003) |
| "Hypothyroidism is a common condition." | ( Graves, L; Klein, RM; Walling, AD, 2003) |
| "Data indicate that hypothyroidism is secondary to Hashimoto's disease (HD)." | ( Arifa, N; Boughattas, S; Chatti, K; Essabbah, H; Hassine, H; Kacem, M; Riahi, N, 2003) |
| "Subclinical hypothyroidism is also associated with an increase risk of cardiovascular disease." | ( Jung, CH; Kang, JH; Kim, BS; Kim, H; Kim, SW; Lee, MH; Lee, WY; Park, JR; Rhee, EJ; Shin, HS; Sung, KC, 2003) |
| "Hypothyroidism is a well defined clinical situation managable thanks to common guidelines." | ( Perazza, L; Scardi, S, 2003) |
| "Subclinical hypothyroidism is defined as elevated TSH in the presence of normal free T4 and T3 levels." | ( Weissel, M, 2003) |
| "Subclinical hypothyroidism is defined as an elevation in serum thyroid-stimulating hormone (TSH) above the upper limit of the reference range (0." | ( Col, NF; Daniels, GH; Surks, MI, 2004) |
| "Subclinical hypothyroidism is characterized by normal serum levels of free thyroxine and triiodothyronine with increased serum levels of thyroid-stimulating hormone (TSH) without symptoms." | ( Camagna, A; Carughi, S; De Cata, A; Giuliani, A; Greco, A; La Viola, M; Mazzoccoli, G; Puzzolante, F, 2003) |
| "Hypothyroidism is associated with increased body weight." | ( Avital, S; Brasesco, O; Cabral, JM; Mehran, A; Rosenthal, R; Szomstein, S, 2004) |
| "Hypothyroidism is common, potentially serious, often clinically overlooked, readily diagnosed by laboratory testing, and eminently treatable." | ( Ladenson, PW; Roberts, CG, 2004) |
| "Subclinical hypothyroidism is an entity based on the laboratory findings of a raised serum thyrotrophin (TSH) concentration and a normal free thyroxine (FT(4)) concentration." | ( Goldie, DJ; Gompels, MM; Kemp, HJ; Lock, RJ; Marden, NA; Thomas, PH, 2004) |
| "Hypothyroidism is commonly thought to cause decreased gastric emptying but is mostly associated with autoimmune disease." | ( Chiu, CT; Hsu, HT; Kao, PF; Lin, JD; See, LC; Tzen, KY, 2004) |
| "While clinical hypothyroidism is associated with frank neuropsychological and affective alterations and is considered one of the causes of reversible dementia, the occurrence of these alterations and their treatment in mild hypothyroidism (MH) remains a controversial issue." | ( Blandini, F; Bono, G; Fancellu, R; Mauri, M; Santoro, G, 2004) |
| "The effect of hypothyroidism is tissue-specific; bone from the femora of birds is not significantly affected by induced hypothyroidism, however, there is a strong positive relationship between the levels of circulating thyroid hormones and the mechanical properties of bone from humeri." | ( Bishop, CM; Bonser, RH; Butler, PJ; Deaton, KE, 2004) |
| "Subclinical hypothyroidism is defined as normal serum free thyroxine and tri-iodothyronine concentrations and a slightly eleveted serum thyrotropin (TSH) concentration." | ( Corvilain, B; Heureux, M, 2004) |
| "To determine if hypothyroidism is associated with an increased risk of glaucoma using a large cohort of patients." | ( Girkin, CA; Lee, PP; McGwin, G; McNeal, SF; Owsley, C, 2004) |
| "Hypothyroidism is a common condition and recent epidemiological studies demonstrated that up to 10 percent of subjects may display its subclinical form." | ( Bruckert, E; Jublanc, C, 2004) |
| "Hypothyroidism is cited as an uncommon cause of ventilator-dependent respiratory failure." | ( Datta, D; Scalise, P, 2004) |
| "Hypothyroidism is an uncommon cause of failure to wean in patients receiving PMV (with an incidence of 3%)." | ( Datta, D; Scalise, P, 2004) |
| "Subclinical hypothyroidism is associated with changes in the cholesterol level, cardiovascular effects and neuromuscular symptoms." | ( Gärtner, R, 2004) |
| "Hypothyroidism is frequently associated with hypercholesterolemia and carries increased risk for atherosclerosis." | ( Karaoglu, AO; Oge, A; Sozmen, E, 2004) |
| "Hypothyroidism is the most common type of thyroid gland dysfunction reported in horses." | ( Frank, N; Messer, NT; Sojka, J, 2002) |
| "Some degree of hypothyroidism is common in the elderly." | ( Andersen, S; Bülow Pedersen, I; Carlé, A; Laurberg, P, 2005) |
| "Mild hypothyroidism is often described in the elderly." | ( Alfos, S; Enderlin, V; Féart, C; Higueret, P; Pallet, V; Vallortigara, J, 2004) |
| "Hypothyroidism is associated with increased morbidity from cardiovascular disease, and an increase in serum osteoprotegerin (OPG) has recently been reported to be associated with the severity of coronary heart disease and cardiovascular mortality." | ( Hiura, Y; Inaba, M; Ishikawa, T; Ishimura, E; Jono, S; Nagasaki, T; Nishizawa, Y; Onoda, N; Shirakawa, K; Tahara, H, 2005) |
| "Clinical hypothyroidism is associated with hyperhomocysteinemia, whereas the opposite is seen in hyperthyroidism." | ( Burge, MR; Colleran, KM; Romero, LA; Upton, DA, 2005) |
| "Hypothyroidism is a common condition presenting a challenge to emergency physicians in diagnosing the underlying etiology of vague complaints." | ( Gossain, VV; Shah, SM; Tews, MC, 2005) |
| "Subclinical hypothyroidism is a common finding in patients with Anderson-Fabry disease, showing an excess prevalence as compared to the normal population." | ( Födinger, M; Gessl, A; Hauser, AC; Lorenz, M; Sunder-Plassmann, G; Voigtländer, T, 2005) |
| "Hypothyroidism is associated with increased morbidity from cardiovascular disease, and adiponectin (ApN) is a newly-identified adipocytokine, which is expressed in human adipose cells and may have a protective effect against the development of coronary artery disease." | ( Hiura, Y; Inaba, M; Ishikawa, T; Ishimura, E; Kumeda, Y; Nagasaki, T; Nishizawa, Y; Onoda, N; Shirakawa, K; Tahara, H, 2005) |
| "Hypothyroidism is associated with neurocognitive impairment." | ( Appelhof, BC; Fliers, E; Huyser, J; Schene, AH; Tijssen, JG; Wekking, EM; Wiersinga, WM, 2005) |
| "Studies of hypothyroidism are often based on referred patients, and limited information is available on the incidence rates of subtypes of hypothyroidism in the general population." | ( Carlé, A; Jorgensen, T; Knudsen, N; Laurberg, P; Ovesen, L; Pedersen, IB; Perrild, H; Rasmussen, LB, 2006) |
| "Hypothyroidism is common in the elderly, especially among women." | ( Cesena, FH; Luz, PL; Xavier, HT, 2005) |
| "Acquired hypothyroidism is rare before age 3 years, and rhabdomyolysis due to hypothyroidism has not previously been reported as a cause of delayed gross-motor development in toddlerhood." | ( Chiu, HK; Gunther, DF; Kletter, GB; Numrych, TE, 2006) |
| "Hypothyroidism is associated with increased morbidity from cardiovascular disease." | ( Guang-Da, X; Hui-Ling, S; Lin-Shuang, Z; Zhi-Song, C, 2005) |
| "Subclinical hypothyroidism is an elevation in serum thyroid-stimulating hormone (TSH) while having normal serum free thyroxine (FT4) and triiodothyronine (FT3) levels." | ( Girgin, A; Hekimsoy, Z; Koral, L; Ozmen, B; Yildirim, C; Yorgancioglu, A, 2006) |
| "Subclinical hypothyroidism is defined as an elevated serum thyroid-stimulating hormone (TSH) level in the face of normal free thyroid hormone values." | ( Caraccio, N; Dardano, A; Monzani, F, 2006) |
| "Overt hypothyroidism is always an indication for substitution with levothyroxine." | ( Janssen, OE; Mann, K, 2006) |
| "Neonatal hypothyroidism is associated with multiple and severe brain alterations." | ( Barreto-Chaves, ML; Battastini, AM; Bavaresco, L; Braganhol, E; Bruno, AN; Sarkis, JJ, 2006) |
| "Subclinical hypothyroidism is not associated with hypertension." | ( Bremner, AP; Bulsara, MK; Feddema, P; Leedman, PJ; Michelangeli, V; O'Leary, P; Walsh, JP, 2006) |
| "Hypothyroidism is the most common clinical consequence of the radiotherapy and lifelong thyroid hormone replacement is required in many cases." | ( Hoshikawa, S; Ito, S; Mori, K; Nakagawa, Y; Ozaki, H; Yoshida, K, 2007) |
| "Hypothyroidism is a frequent complication of sunitinib therapy." | ( Alexander, EK; Chen, MH; Demetri, GD; Desai, J; Dychter, SS; Frates, MC; George, S; Larsen, PR; Marqusee, E; Morgan, JA; Yassa, L, 2006) |
| "Hypothyroidism is one of the common causes of the secondary hypercholesterolemia." | ( Brzosko, M; Lukjanowicz, M; Trzcińska-Butkiewicz, B, 2006) |
| "Treatment of hypothyroidism is by giving levothyroxine orally, and the dose is to be titrated to keep the serum TSH within the normal range." | ( Jayakumar, RV, 2006) |
| "Sub-clinical hypothyroidism is defined by elevated serum thyroid-stimulating hormone level in the face of normal free thyroid hormone values." | ( Antonelli, A; Franzoni, F; Galetta, F; Rossi, M; Santoro, G, 2006) |
| "Mild hypothyroidism is associated only with a very mild defect in renal acid handling, which appears to be mainly located in the proximal tubule and is compensated by the distal nephron." | ( Kovacikova, J; Mohebbi, N; Nowik, M; Wagner, CA, 2007) |
| "Usually the hypothyroidism is mild and resolves spontaneously upon cessation of gargling." | ( Kimura, H; Ohmori, T; Sato, K; Shiratori, K; Takano, K; Yamada, E; Yamazaki, K, 2007) |
| "Subclinical hypothyroidism is characterised by elevated serum thyroid stimulating hormone (TSH) concentrations in association with normal free thyroid hormones." | ( Bandyopadhyay, SK; Basu, AK; Chakrabarti, S; Murmu, BK; Pal, SK; Pathak, HS; Roy, P, 2006) |
| "Moreover, hypothyroidism is also associated with obstetric complications and morbidity to the fetus." | ( Da Costa, SM; De Almeida, CA; Neto, LV; Vaisman, M, 2007) |
| "As hypothyroidism is a stress for normal animals, we wanted to explore whether any compensatory pathway exists to balance the reduced lysyl hydroxylation of collagen in hypothyroid rat ovary." | ( Bhattacharya, S; Ghosh, P; Roy, SS; Saha, SK, 2007) |
| "Hypothyroidism is one of the earliest endocrine effects of craniospinal irradiation (CSI)." | ( Biassoni, V; Bombardieri, E; Collini, P; Fossati-Bellani, F; Gandola, L; Marchianò, A; Massimino, M; Pallotti, F; Pignoli, E; Seregni, E; Serra, A; Spreafico, F; Terenziani, M, 2007) |
| "Hypothyroidism is 1 of the complications that follow treatment of various head and neck cancers." | ( Ho, AC; Ho, WK; Lam, PK; Wei, WI; Yuen, AP, 2008) |
| "In conclusion, hypothyroidism is a frequent complication in patients treated with radiotherapy and total laryngectomy for laryngeal cancer, especially when treatment includes hemithyroidectomy." | ( Ho, AC; Ho, WK; Lam, PK; Wei, WI; Yuen, AP, 2008) |
| "Subclinical hypothyroidism is defined as an elevated serum thyroid-stimulating hormone (TSH) level with normal free thyroid hormones values." | ( Atallah, AN; Saconato, H; Valente, O; Villar, HC, 2007) |
| "1." | ( Dirican, M; Sarandöl, E; Taş, S, 2007) |
| "Subclinical hypothyroidism is characterized by high serum TSH concentrations, together with normal free T4 values." | ( Franklyn, JA, 2007) |
| "Hypothyroidism is one of the most common disorders encountered in an endocrine office practice." | ( Burman, KD; Devdhar, M; Ousman, YH, 2007) |
| "Hypothyroidism is often associated with adverse cardiovascular risk factors such as high cholesterol together with hypertension, endothelial dysfunction, and other atherosclerotic cardiovascular risk factors." | ( Feldt-Rasmussen, U, 2007) |
| "Because hypothyroidism is easily accessible to treatment, screening of thyroid abnormalities is mandatory every three months to improve quality of life of these patients." | ( Bihan, H; Cohen, R; des Guetz, G; Krivitzky, A; Uzzan, B, 2007) |
| "Hypothyroidism is a common endocrinopathy in dogs but is rare in cats." | ( Finora, K; Greco, D, 2007) |
| "Hypothyroidism is very often subclinical in nature and not easily recognized without specific screening programs." | ( Rashid, M; Rashid, MH, 2007) |
| "Ascites caused by hypothyroidism is rare and the pathogenesis is unclear." | ( Imaeda, K; Joh, T; Kamiya, Y; Kimura, R; Mizuno, T; Okayama, N; Wakami, K; Yamada, K, 2007) |
| "Hypothyroidism is frequently associated with different neuromuscular disorders." | ( Masmoudi, S; Mrabet, A; Mrabet, H, 2007) |
| "Hypothyroidism is a common disorder, which is mainly treated in primary rather than secondary care." | ( Macleod, AF; Moulik, PK; Rangan, S; Tahrani, AA, 2007) |
| "Hypothyroidism is associated with accumulation of hyaluronic acid within various tissues, additional fluid retention due to reduced cardiac output and reduced thermogenesis." | ( Weaver, JU, 2008) |
| "Defining congenital hypothyroidism is particularly complex in premature neonates because prematurely born infants often have a low free thyroxine value and low or normal TSH value, termed as transient hypothyroxinemia of prematurity." | ( Chace, DH; Clark, RH; Kelleher, AS; Spitzer, AR; Steinbach, M, 2008) |
| "Hypothyroidism is associated with increased body weight." | ( Cohen, S; Fazylov, R; Merola, S; Soto, E, 2008) |
| "Hypothyroidism is associated with an increased risk for cardiovascular disease." | ( Guang-da, X; Hui-ling, S; Jie, H, 2008) |
| "Adult-onset hypothyroidism is associated with neurological changes such as cognitive dysfunction and impaired learning, which may be related to alterations of synaptic plasticity." | ( Alfos, S; Enderlin, V; Higueret, P; Micheau, J; Vallortigara, J, 2008) |
| "Hypothyroidism is a common disease that is often undiagnosed or misdiagnosed because the signs and symptoms are often confused with other conditions." | ( Hennessey, JV; Scherger, JE, 2007) |
| "Acquired hypothyroidism is not often associated with obesity, and ultrasound usually has no added diagnostic value." | ( Bulvik, S; de Vries, L; Phillip, M, 2009) |
| "Hypothyroidism is associated with elevated cardiovascular risk, not fully explained by classical risk factors." | ( Clausen, P; Feldt-Rasmussen, B; Feldt-Rasmussen, U; Mersebach, H; Nielsen, B, 2009) |
| "Hypothyroidism is a manifestation of multi-hormonal resistance in pseudohypoparathyroidism type Ia (PHP Ia)." | ( Balavoine, AS; Cardot-Bauters, C; d'Herbomez, M; Ladsous, M; Velayoudom, FL; Vlaeminck, V; Wemeau, JL, 2008) |
| "MMI-induced mild hypothyroidism is associated with endothelial dysfunction caused by a reduced NO availability, secondary to oxidative excess." | ( Blandizzi, C; Colucci, R; Daghini, E; Dardano, A; Del Tacca, M; Duranti, E; Fornai, M; Ghisu, N; Monzani, F; Polini, A; Taddei, S; Versari, D; Virdis, A, 2009) |
| "Subclinical hypothyroidism is also associated with the risk of progression to overt hypothyroidism and with the risk of neuropsychiatric effects." | ( Krysiak, R; Marek, B; Okopień, B, 2008) |
| "Subclinical hypothyroidism is a rather frequent pathology as its prevalence ranges from 1% among young adults to 10% beyond 55 years of age." | ( Giet, D; Loor, M, 2008) |
| "Hypothyroidism is more frequent in woman and raises with age." | ( Basurto, L; Córdova Pérez, N; Hernández Valencia, M; Manuel Apolinar, L; Ruiz, M; Vargas, A; Vargas, C; Zárate, A, 2008) |
| "Subclinical hypothyroidism is a possible cause of sensory neuropathy and hormone replacement therapy can prompt nerve regeneration." | ( Camozzi, F; Ciano, C; Lauria, G; Lombardi, R; Penza, P, 2009) |
| "Patients with hypothyroidism are at a higher risk for coronary vascular disease." | ( Gerdes, AM; Liu, Y; Redetzke, RA; Sherer, BA; Wang, D, 2009) |
| "Hypothyroidism is a common problem in clinical practice, with diverse manifestations." | ( Mahadevan, S; Radhika, R; Sathya, A; Sriram, U, 2009) |
| "Hypothyroidism is not accompanied by significant changes in circulating Ghrelin." | ( Bartalena, L; Bogazzi, F; Broglio, F; Dalle Mule, I; Gandolfo, M; Genovesi, M; Ghigo, E; Grasso, L; Lai, A; Lombardi, V; Martino, E; Tanda, ML; Ultimieri, F, 2009) |
| "Hypothyroidism is frequently associated with subtle behavioral and psychiatric symptoms." | ( Bauer, M; Berman, SM; Geist, CL; London, ED; Martinez, D; Miller, K; Phelps, ME; Rasgon, N; Schlagenhauf, F; Silverman, DH; van Herle, A; van Herle, K; Whybrow, PC, 2009) |
| "Overt hypothyroidism is associated with cognitive impairment, which can be reversed if treated early and appropriately." | ( Barrett-Connor, E; Kramer, CK; Kritz-Silverstein, D; von Mühlen, D, 2009) |
| "Long-term treated hypothyroidism is not associated with impaired CF or depressed mood in old age." | ( Barrett-Connor, E; Kramer, CK; Kritz-Silverstein, D; von Mühlen, D, 2009) |
| "Chronic hypothyroidism is associated with an increased risk for cardiovascular disease attributed, in part, to increased serum cholesterol and atherosclerosis." | ( Gao, L; Han, Y; Liu, J; Zhao, J; Zhou, X, 2009) |
| "Hypothyroidism is an often underreported complication of cancer treatment." | ( Kurtin, SE, 2009) |
| "Hypothyroidism is one of the common endocrine abnormalities which are central features of POEMS syndrome." | ( Dun, XY; Hou, J; Xi, H; Yuan, ZG; Zhou, F, 2009) |
| "Hypothyroidism is a common endocrine disorder which is easily treatable by an appropriate thyroid hormone replacement therapy in the majority of patients." | ( Georges, G; Häring, HU; Klein, R; Mörike, K; Müssig, K; Schnauder, G; Sträter, J, 2009) |
| "Overt hypothyroidism is associated with elevation of diastolic blood pressure; however the association of subclinical hypothyroidism (SH) with arterial blood pressure (ABP) alteration is unknown." | ( Almeida, CP; Ferreira, MM; Mansur, VA; Reuters, VS; Teixeira, Pde F; Vaisman, M, 2010) |
| "Subclinical hypothyroidism is a common condition and it is often monitored biochemically without treatment." | ( Andersen, S; Karmisholt, J; Laurberg, P, 2010) |
| "Hypothyroidism is associated with a disturbance of behaviour and mood." | ( Banati, RB; Keay, KA; Kilburn-Watt, E, 2010) |
| "Overt hypothyroidism is associated with an increase in oxidative stress, and hypercholesterolemia has a stronger influence on development of oxidative stress in hypothyroid conditions compared with thyroid hormones." | ( Bagatini, MD; Duarte, MM; Loro, VL; Menezes, C; Moresco, RN; Santi, A; Schetinger, MR, 2010) |
| "Most fetal goitrous hypothyroidisms are reportedly caused by the maternal use of an antithyroid drug or fetal dyshormonogenesis." | ( Ashida, T; Hirabayashi, K; Kanai, M; Kikuchi, N; Kobara, H; Miyake, M; Nishio, S; Ohira, S; Osada, R; Shiozawa, T, 2010) |
| "Subclinical hypothyroidism is associated with an increased risk of atherosclerosis." | ( Borawski, J; Budlewski, T; Górska, M; Kowalska, I; Nikołajuk, A; Otziomek, E; Strączkowski, M, 2011) |
| "Hypothyroidism is related to multiple cognitive deficits including working memory dysfunction, of which the underlying neural correlates were rarely studied." | ( He, XS; Li, N; Ma, N; Pan, ZL; Wang, ZX; Zhang, DR; Zhang, XC; Zhou, JN; Zhu, DF, 2011) |
| "Hypothyroidism is related to alterations of TID within DMN regions during working memory processing." | ( He, XS; Li, N; Ma, N; Pan, ZL; Wang, ZX; Zhang, DR; Zhang, XC; Zhou, JN; Zhu, DF, 2011) |
| "Consumptive hypothyroidism is a rare syndrome resulting from increased catabolism of T(4) and T(3) by increased type 3 iodothyronine deiodinase (D3) activity." | ( Howard, D; Huang, S; Klopper, JP; La Rosa, FG; Mulcahey, M; Salvatore, D; Sang-Lee, J; Wachs, M, 2011) |
| "Hypothyroidism is frequently observed under sunitinib therapy." | ( Bladou, F; Boher, JM; Brunelle, S; Deville, JL; Eymard, JC; Gravis, G; Marcy, M; Narbonne, H; Sabatier, R; Salem, N; Viens, P; Walz, J, 2012) |
| "Hypothyroidism is a common complication in patients receiving tyrosine kinase inhibitors." | ( Fujii, M; Fujisawa, M; Kitajima, K; Maeda, T; Miyake, H; Ohno, Y; Sugimura, K; Takahashi, S; Yoshikawa, T, 2012) |
| "Hypothyroidism is six times more common in women, affecting up to 40/10,000 each year (compared with 6/10,000 men)." | ( Nygaard, B, 2010) |
| "Hypothyroidism is associated with an increase in a number of coronary heart disease (CHD) risk factors including dyslipidemia, hypertension, and elevated levels of homocysteine." | ( Brennan, DM; Hoar, B; Hoogwerf, BJ; McQuade, C; Skugor, M; Stevenson, C, 2011) |
| "Conversely, hypothyroidism is accompanied by a marked decrease in sensitivity to sympathetic agonists with an increase of peripheral vascular resistance and arterial stiffness." | ( Al-Nahhas, A; Armigliato, M; Beltramello, G; Grassetto, G; Marzola, MC; Mazza, A; Montemurro, D; Rampin, L; Rubello, D; Zorzan, S; Zuin, M, 2011) |
| "Subclinical hypothyroidism is associated with an increasing number of adverse effects including infertility, miscarriage, preterm delivery, and breech presentation at birth." | ( Brent, GA; Milanesi, A, 2011) |
| "Overt hypothyroidism is a state with thyroid hormone deficiency." | ( Mansourian, AR, 2010) |
| "Congenital hypothyroidism is screened for in the UK using blood spot thyroid-stimulating hormone (TSH) screening at 5-8 d of age." | ( Barton, J; Evans, C; Gregory, JW; Hallett, A; Moat, S; Warner, J, 2011) |
| "Hypothyroidism is known to be one of the causes of this disorder." | ( Nozu, T; Ohira, M; Okumura, T; Yoshida, Y, 2011) |
| "Primary hypothyroidism is the most common side effect, although thyrotoxicosis and effects on thyroid-stimulating hormone secretion and thyroid hormone metabolism have also been described." | ( Hamnvik, OP; Larsen, PR; Marqusee, E, 2011) |
| "Hypothyroidism is an underactive thyroid gland that cannot make enough thyroid hormone to keep the body running normally." | ( Ali, EM; Ibrahim, W; Mansour, MA; Tousson, E, 2012) |
| "Congenital hypothyroidism is a pediatric endocrine disorder caused by insufficient endogenous thyroid hormone production." | ( McAndrews, MP; Rovet, J; Sheard, ED; Wheeler, SM, 2012) |
| "Subclinical hypothyroidism is defined as elevated serum TSH with normal free T(4) and free T(3) levels." | ( Aybike, K; Erdogan, M; Ganidagli, S; Kösenli, A; Kulaksizoglu, M; Mehmet, E; Mustafa, K, 2012) |
| "Primary hypothyroidism is the most common endocrine disease." | ( Chakera, AJ; Pearce, SH; Vaidya, B, 2012) |
| "Hypothyroidism is closely associated with NAFLD independently of known metabolic risk factors, confirming a relevant clinical relationship between these two diseases." | ( Chung, GE; Kim, D; Kim, W; Kim, YJ; Lee, HS; Park, MJ; Yim, JY; Yoon, JH, 2012) |
| "Hypothyroidism is the result of inadequate production of thyroid hormone or inadequate action of thyroid hormone in target tissues." | ( Almandoz, JP; Gharib, H, 2012) |
| "Hypothyroidism is usually treated with thyroxine doses on patient weight." | ( García-Mayor, RV; Luna Cano, R; Penín Álvarez, M; Seoane Cruz, I, 2012) |
| "Hypothyroidism is a protective state against EG because the changes in the renal function were smaller than in the euthyroid state." | ( Cano-Europa, E; Estévez-Carmona, MM; Franco-Colin, M; Meléndez-Camargo, E; Ortiz-Butron, R; Pineda-Reynoso, M, 2013) |
| "Hypothyroidism is often accompanied with decline of kidney function, or inability to maintain electrolyte balance." | ( Dragović, T, 2012) |
| "Consumptive hypothyroidism is a rare condition related to massive infantile hemangiomas producing an excess of the thyroid-hormone-inactivating enzyme type 3 iodothyronine deiodinase." | ( Chiumello, G; Cortinovis, F; Di Frenna, M; Gelmetti, C; Passoni, A; Persani, L; Rabbiosi, S; Vigone, MC; Weber, G, 2012) |
| "Overt hypothyroidism is classically treated using L-thyroxine; elderly patients require a low initial dose that is increased every 4 to 6 weeks until normalization of TSH levels." | ( Bensenor, IM; Lotufo, PA; Olmos, RD, 2012) |
| "Hypothyroidism is a procoagulant state; hypothyroid females have greater risk of DVT than hypothyroid males." | ( Kumar, SS; Prasad, CV; Rajesh, J; Shakir, RM; Umadevi, V; Vijayashankar, C, 2011) |
| "Adult hypothyroidism is a highly prevalent condition that impairs processes, such as learning and memory." | ( Aliaga, E; Bueno, SM; Carreño, LJ; Cortés, C; Court, F; Eugenin, E; Gayol, S; Gonzalez, PA; Ibarra, P; Jadue, C; Kalergis, AM; Keitel, C; Marassi, MP; Naranjo, D; Noches, V; Riedel, CA; Rosenthal, D; Wohllk, N, 2012) |
| "Gestational hypothyroidism is a prevalent disorder in pregnant women." | ( Alves, IG; Badauê-Passos, D; Dias, DP; Jesus, CS; Loureiro, SM; Santana-Filho, VJ; Santos, MR; Santos, PR; Santos, SO, 2012) |
| "Hypothyroidism is a clinical disorder commonly encountered by the primary care physician." | ( Gaitonde, DY; Rowley, KD; Sweeney, LB, 2012) |
| "Hypothyroidism is present in up to 3% of all pregnant women." | ( Pearce, E; Stagnaro-Green, A, 2012) |
| "Secondary hypothyroidism is observed in children after brain damage." | ( Ben-Skowronek, I; Wisniowiecka, M, 2012) |
| "Hypothyroidism is a common endocrine disorder that mainly affects women and the elderly." | ( Grossmann, M; MacIsaac, RJ; So, M, 2012) |
| "Primary hypothyroidism is a common disorder often associated with depression." | ( Neal, JM; Yuhico, RJ, 2012) |
| "Hypothyroidism is accepted as one of the hormonal factors leading to non-allergic rhinitis." | ( Basak, S; Culhaci, N; Dost, T; Eyigor, H; Kozaci, D; Ulutas, P, 2012) |
| "Hypothyroidism is treated with oral levothyroxine." | ( Araki, FS; de Carvalho, GA; Graf, H; Perez, CL, 2013) |
| "Hypothyroidism is associated with increased oxidative stress." | ( Bitla, AR; Reddy, VS; Sachan, A; Srinivas Rao, PV; Suchitra, MM; Suresh, V; Tejovathi, B, 2013) |
| "Hypothyroidism is a rare cause of dilated cardiomyopathy." | ( Agostini, D; Hardouin, J; Legallois, D; Manrique, A; Milliez, P, 2013) |
| "Subclinical hypothyroidism is a health state that is associated with hypercholesterolemia, infertility, iron-deficiency anemia, and poor obstetric outcome." | ( Asadipooya, K; Kalantarhormozi, M; Nabipour, I; Omrani, GR; Ravanbod, M, 2013) |
| "When hypothyroidism is newly discovered during pregnancy, we suggest initiating the treatment with the following LT4 doses: 1." | ( Abalovich, M; Alcaraz, G; Astarita, G; Calabrese, C; Frydman, M; Gutiérrez, S; Kitaigrodsky, A; Szuman, G; Vázquez, A, 2013) |
| "Central hypothyroidism is a well-recognized side effect of bexarotene." | ( Appetecchia, M; Baldelli, R; Barnabei, A; Corsello, SM; Paragliola, R; Torino, F, 2013) |
| "Overt hypothyroidism is associated with an increased risk for developing cardiovascular disease." | ( Aytan, P; Kutluturk, F; Ozturk, B; Tasliyurt, T; Yelken, BM; Yılmaz, A; Yuce, S, 2013) |
| "Hypothyroidism is a chronic condition characterized by abnormally low thyroid hormone production." | ( Afzal, M; Al-Abbasi, FA; Anwar, F; Kazmi, I; Semwal, S, 2014) |
| "Hypothyroidism is a common AE associated with ethionamide, p-aminosalicylic acid (PAS), and stavudine." | ( Andries, A; Dalal, A; Das, M; Desai, C; Fernandes, D; Isaakidis, P; Khan, S; Mansoor, H; Migliori, GB; Paryani, R; Saranchuk, P; Sotgiu, G; Verma, R, 2013) |
| "Hypothyroidism is not commonly considered as a complication of radiotherapy to the head and neck region." | ( Bernát, L; Hrušák, D, 2014) |
| "Subclinical hypothyroidism is the precursor to hypothyroidism because it has a tendency to transform into hypothyroidism." | ( Ardic, C; Cakirca, M; Cikrikcioglu, MA; Erkoc, R; Karatoprak, C; Kesgin, S; Kiskac, M; Yildiz, K; Zorlu, M, 2014) |
| "Hypothyroidism is the most common pregnancy-related thyroid disorder, affecting 3-5% of all pregnant women." | ( Cooper, DS; Patil-Sisodia, K; Shan, Z; Teng, W, 2013) |
| "Hypothyroidism is known to exert significant structural and functional changes to the developing central nervous system, and can lead to the establishment of serious mental retardation and neurological problems." | ( Al-Humadi, H; Koromilas, C; Liapi, C; Skandali, N; Stolakis, V; Tsagianni, A; Tsakiris, S; Zarros, A, 2014) |
| "Subclinical hypothyroidism is a common condition, and its prevalence increases with age." | ( Baumgartner, C; Bischoff, T; Collet, TH; Frey, P; Haller, DM; Pitteloud, N; Rodondi, N; Rosemann, T; Sykiotis, G; Virgini, V, 2014) |
| "Hypothyroidism is a common clinical side effect of lithium treatment, whereas parkinsonism is a very rare adverse event." | ( Basile, G; Epifanio, A; Mandraffino, R; Trifirò, G, 2014) |
| "Hypothyroidism is a very common, yet often overlooked disease." | ( Dubbs, SB; Spangler, R, 2014) |
| "Hypothyroidism is six times more common in women, affecting up to 40 in 10,000 each year (compared with 6/10,000 men)." | ( Nygaard, B, 2014) |
| "Hypothyroidism is a common adverse event in patients treated with anti-VEGFR-2 targeting agents and may be a valuable predictive factor of efficacy." | ( Cao, J; Hu, X; Lv, F; Wang, B; Wang, L; Wang, Z; Zhang, J, 2014) |
| "Hypothyroidism is a growing medical concern." | ( Bhanja, S; Chainy, GB; Mukherjee, S; Roy, A; Samanta, L, 2014) |
| "Hypothyroidism is an endocrine disease with various clinical manifestations." | ( Akbarnia, S; Pourrajab, F; Rahmanian, M; Zare-Khormizi, MR, 2014) |
| "Hypothyroidism is one of the most common endocrinopathies in reproductive-age and pregnant women." | ( Caughey, AB; Patton, PE; Samuels, MH; Trinidad, R, 2014) |
| "Hypothyroidism is a common endocrine disorder frequently accompanied by alterations in lipid metabolism, such as hypercholesterolemia and high circulating triglycerides, both risk factors for nonischemic cardiomyopathy." | ( Baumgartner-Parzer, S; Duan, H; Einwallner, E; Gessl, A; Hoffmann, M; Krebs, M; Krššák, M; Luger, A; Niessner, A; Scherer, T; Trattnig, S; Winhofer, Y; Wolf, P, 2014) |
| "Consumptive hypothyroidism is a rare condition usually described in association with diffuse infantile hemangioma of the liver, over-expressing type 3 iodothyronine-deiodinase." | ( Crivellaro, C; De Corti, F; Luzzatto, C; Zanon, GF, 2015) |
| "However, hypothyroidism is a rare cause of pseudo-obstruction so here we present a case report of Hashimoto's encephalopathy with gut pseudo-obstruction in an undiagnosed hypothyroid patient." | ( Bhat, MS; Shera, IA; Vyas, A; Yousuf, Q, 2014) |
| "Hypothyroidism is associated with increased cardiovascular morbidity, which cannot be fully explained by the atherogenic lipid profile observed in these patients." | ( Dey Sarkar, P; Singh, S, 2014) |
| "Subclinical hypothyroidism is associated with multiple adverse outcomes in the mother and fetus, including spontaneous abortion, pre-eclampsia, gestational hypertension, gestational diabetes, preterm delivery, and decreased IQ in the offspring." | ( Negro, R; Stagnaro-Green, A, 2014) |
| "Subclinical hypothyroidism is suggested to increase cardiovascular risk." | ( Gilowski, W; Krysiak, R; Okopien, B; Szkrobka, W, 2014) |
| "Subclinical hypothyroidism is more likely to be prevalent in the high iodine intake areas than in the iodine deficient or sufficient areas." | ( Du, Y; Fan, Z; Gao, Y; Liu, S; Meng, F; Sun, D; Wu, J, 2014) |
| "Subclinical hypothyroidism is a biochemical diagnosis characterized by raised thyroid stimulating hormone and normal free T4, without clinical features of hypothyroidism." | ( Shriraam, M; Sridhar, M, 2014) |
| "Subclinical hypothyroidism is often a benign problem which requires expectant management with periodic monitoring of thyroid function tests and natural progression to overt hypothyroidism occur lot less frequently than expected." | ( Shriraam, M; Sridhar, M, 2014) |
| "Hypothyroidism is known to be closely associated with lipid metabolism." | ( Chai, Y; Chen, S; Dong, X; Li, W; Lou, Z; Tan, G; Wu, S; Zhu, Z, 2015) |
| "Hypothyroidism is a late side effect after curative radiotherapy in the head and neck region." | ( Endo, K; Kondo, S; Masatani, T; Murono, S; Tsuji, A; Wakisaka, N; Yoshizaki, T, 2015) |
| "TAI and hypothyroidism are not associated with low ovarian reserve." | ( Camus, M; Polyzos, NP; Poppe, K; Sakkas, E; Tournaye, H; Vaiarelli, A, 2015) |
| "TAI and hypothyroidism are not associated with low ovarian reserve." | ( Camus, M; Polyzos, NP; Poppe, K; Sakkas, E; Tournaye, H; Vaiarelli, A, 2015) |
| "Subclinical hypothyroidism is associated with a number of cardiovascular risk factors, yet only limited data exist on long-term outcome of levothyroxine treatment of this condition with respect to hard end-points." | ( Andersen, MN; Faber, J; Gislason, GH; Madsen, JC; Olsen, AM; Selmer, C; Torp-Pedersen, C, 2015) |
| "Hypothyroidism is one of the side-effects caused by regorafenib." | ( Hagino, A; Hama, T; Kawakami, K; Mae, Y; Mizunuma, N; Suenaga, M; Sugita, K; Suzuki, K; Toya, W; Yamaguchi, T; Yokokawa, T, 2015) |
| "Hypothyroidism is associated with an increased risk of coronary artery disease, beyond that which can be explained by its association with conventional cardiovascular risk factors." | ( Gharib, H; Lerman, A; Lerman, LO; Sara, JD; Zhang, M, 2015) |
| "Hypothyroidism is a known cause of pleural, pericardial and abdominal effusions, as reported in several case reports." | ( Čaržavec, D; Gaćina, P; Kruljac, I; Kust, D; Ostojić, J; Peternac, AŠ; Prpić, M, 2016) |
| "Hypothyroidism is one of the most common endocrine disorders in young women and affects 3% to 4% of all pregnancies." | ( Foeller, ME; Silver, RM, 2015) |
| "Hypothyroidism is one condition associated with sluggish erythropoesis." | ( Anantarapu, S; Epuri, S; Mukka, A; Phaneendra, BV; Reddy, AP; Sachan, A; Suchitra, MM; Vaikkakara, S; Vemvakam, D, 2015) |
| "Primary hypothyroidism is a disease commonly encountered by GPs and internal medicine doctors." | ( Kox-van Gastel, P; Susanto, CR; van Moll, CC, 2015) |
| "Hypothyroidism is commonly associated with a variety of psychiatric conditions, most commonly depression and cognitive impairment, but up to 5% to 15% of symptomatically hypothyroid patients may develop a nonaffective psychosis, classically referred to as "myxedema madness." | ( Catalano, G; Hines, A; Stewart, JT, 2015) |
| "Hypothyroidism is a common disorder due to inadequate thyroid hormone secretion." | ( , 2015) |
| "Patients with hypothyroidism are increasingly enquiring about the benefit of using combination therapy of levothyroxine (LT4) and liothyronine (LT3) as a potential treatment for hypothyroidism." | ( Farahani, P; Kraut, E, 2015) |
| "Hypothyroidism is reported to contribute to the development of nonalcoholic fatty liver disease (NAFLD)." | ( Bang, KB; Cho, YK; Kwon, HJ; Lee, KW; Lee, MY; Rhee, EJ, 2015) |
| "TKI-induced hypothyroidism is a highly complicated issue, because of not only the unrealized toxicological mechanisms, but also different incidences of individual TKI drugs." | ( Lin, Z; Shu, M; Wang, R; Zai, X; Zhang, B, 2016) |
| "Obesity and hypothyroidism are both common disorders within the general population." | ( Basolo, A; Ceccarini, G; Fierabracci, P; Magno, S; Martinelli, S; Pelosini, C; Piaggi, P; Querci, G; Ricco, I; Salvetti, G; Santini, F; Scartabelli, G; Tamberi, A; Vitti, P, 2016) |
| "Hypothyroidism is a condition in which the serum levels of thyroid hormones are below that necessary to carry out physiological functions in the body." | ( Aiceles, V; da Fonte Ramos, C, 2016) |
| "Chronic canine hypothyroidism is associated with blood-brain barrier (BBB) disruption." | ( Huckle, WR; Inzana, KD; Pancotto, TE; Rossmeisl, JH; Zimmerman, KL, 2016) |
| "The diagnosis of hypothyroidism is based on the findings of an increased serum TSH (above the reference range) and decreased serum free T4 (below the reference range) concentration." | ( Metso, S; Moilanen, L; Niskanen, L; Nuutila, P; Salmela, P; Schalin-Jäntti, C, 2016) |
| "Hypothyroidism is characterized by elevated lipid profiles and thyroid stimulation hormone (TSH)." | ( Hongasandra, N; Metri, K; Nilakanthan, S; Raghuram, N, 2016) |
| "Fatigue und hypothyroidism are two common side effects of TKI therapy that can often appear simultaneously." | ( Keck, B; Lieb, V; Lüdecke, G; Sikic, D, 2016) |
| "Hypothyroidism is currently a condition that can be treated, but not cured." | ( Jonklaas, J, 2016) |
| "Overt hypothyroidism is frequently found in patients with type 2 diabetes mellitus (T2DM), but it remains unknown the relationship between subclinical hypothyroidism (SCH) and T2DM." | ( Cho, JH; Kim, HJ; Lee, HW; Lee, IK; Lee, JH; Moon, JS; Park, IR; Won, KC; Yoon, JS, 2016) |
| "Hypothyroidism is an adverse effect of certain anti-tuberculosis drugs." | ( Bares, R; Daniel, H; Dittmann, H; Gallwitz, B; Khalid, N; Reimold, M; Schmotzer, C, 2016) |
| "Hypothyroidism is associated with changes in bone metabolism." | ( Aktas Yılmaz, B; Arslan, M; Cakır, N; Elbeg, S; Konca Degertekin, C; Pasaoglu, H; Pasaoglu, OT; Turhan Iyidir, O, 2016) |
| "Hypothyroidism is characterized by hypometabolism, and may be seen as a part of secondary failure due to pituitary insufficiency or tertiary due to hypothalamic disease." | ( Feldt-Rasmussen, U; Klose, M, 2016) |
| "Hypothyroidism is one of the causes of hyponatremia, thus thyroid-stimulating hormone determination is mandatory during the evaluation of patients with reduced serum sodium levels." | ( Elisaf, MS; Filippatos, TD; Liamis, G; Liontos, A, 2017) |
| "Hypothyroidism is an undesirable sequela of both surgery and radiotherapy, the two most commonly used modalities of treatment." | ( Biswas, KD; Dutta, S; Ghatak, S; Haldar, D; Sen, I; Sinha, R, 2016) |
| "Subclinical hypothyroidism is a common condition that may lead to impaired cardiac function." | ( Andersen, MN; Faber, J; Gislason, GH; Kristensen, SL; Madsen, JC; Olsen, AS; Selmer, C; Torp-Pedersen, C, 2016) |
| "Hypothyroidism is a common condition of hormone deficiency, and oral administration of thyroid hormones is currently the only available treatment option." | ( Atala, A; Liu, Y; Opara, EC; Yang, Y; Zhao, W, 2017) |
| "Subclinical hypothyroidism is typically defined as an elevated TSH and normal FT4 levels." | ( Kim, CS; Kroopnick, JM, 2016) |
| "Hypothyroidism is the most common condition linked to a hormone deficiency, nevertheless data on its prevalence are scarce in Spain." | ( Escribano-Serrano, J; García-Bonilla, A; Hormigo-Pozo, A; Mancera-Romero, J; Márquez-Ferrando, M; Méndez-Esteban, MI; Michán-Doña, A; Payá-Giner, C; Santos-Sánchez, V, 2016) |
| "Hypothyroidism is a state of thyroid hormone insufficiency that results in decreased metabolism and secondary effects including fatigue and weight gain." | ( Kelley, S, 2016) |
| "Subclinical hypothyroidism is associated with increased levels of serum endocan, ADMA, and TGF-β, which are new markers for ED." | ( Arpaci, D; Ciftci, IH; Ergenc, H; Gurol, G; Karakece, E; Tamer, A; Tocoglu, AG, 2016) |
| "Subclinical hypothyroidism is defined by elevated serum thyrotropin in presence of normal free thyroid hormones." | ( Delitala, AP; Delitala, G; Fanciulli, G; Maioli, M, 2017) |
| "Hypothyroidism is prevalent in the population, consistent with reported literature." | ( Baumer, N; Berrier, K; Brasington, C; Cannon, S; Crissman, B; Davidson, E; Elsharkawi, I; Florez, JC; Kishnani, P; Lavigne, J; Lombardo, A; Lyerly, J; McDonough, ME; Ozonoff, A; Schwartz, A; Sharr, C; Skotko, BG; Sparks, S; Stock-Guild, K; Toler, TL; Vellody, K; Voelz, L, 2017) |
| "Hypothyroidism is a common condition of thyroid hormone deficiency, which is readily diagnosed and managed but potentially fatal in severe cases if untreated." | ( Bianco, AC; Chaker, L; Jonklaas, J; Peeters, RP, 2017) |
| "Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient stimulation by TSH." | ( Beck-Peccoz, P; Giavoli, C; Lania, A; Rodari, G, 2017) |
| "Hypothyroidism is the most frequent endocrinologic disorder after diabetes." | ( Bashkin, A; Nodelman, M, 2017) |
| "Congenital hypothyroidism is a preventable cause of intellectual disability." | ( Hawke, A; Neylon, OM; Ruth, E; Stanzelova, A, 2017) |
| "Subclinical hypothyroidism is caused by thyroid hormone deficit and can lead to impairments in mood and cognition." | ( Chekhonin, VP; Gurina, OI; Melnikov, PA; Morozova, AY; Zorkina, YA; Zubkov, EA, 2017) |
| "Fetal goitrous hypothyroidism is mainly caused by maternal treatment of Graves' disease." | ( Kobayashi, M; Naito, A; Nemoto, A; Saito, T; Sugita, K; Yagasaki, H, 2017) |
| "Sub-clinical hypothyroidism is very common in Primary Care clinics." | ( Bellido-Moyano, C; González-Rodríguez, ME; Hidalgo-Requena, A; López-Macías, I; Pérez-Membrive, E; Pérula-de Torres, LA, 2018) |
| "Subclinical hypothyroidism is common in children with CHC receiving treatment with pegylated IFN-α-2b and RBV, but in most cases is transient." | ( Azzari, C; Cananzi, M; D'Antiga, L; Indolfi, G; Nebbia, G; Resti, M; Ricci, S; Serranti, D; Stagi, S, 2018) |
| "Hyper- and hypothyroidism are some of the most common endocrinopathies that cause many metabolic disorders including amino acids metabolism." | ( Koloshko, O; Korda, М; Melnyk, A; Nechiporuk, V; Zaichko, N, 2017) |
| "Here, subclinical hypothyroidism is 5." | ( Khan, NZ; Mishu, FA; Muttalib, MA; Nesa, A; Sultana, GS, 2017) |
| "Hypothyroidism is an established adverse effect of radiation therapy for head and neck cancer, and computed tomography (CT) density of the thyroid gland is lower in hypothyroid than euthyroid individuals." | ( Aizawa, T; Ishibashi, N; Maebayashi, T; Matsushita, J; Okada, M; Sakaguchi, M, 2018) |
| "Subclinical hypothyroidism is associated with dyslipidemia and atherosclerosis." | ( Beukhof, CM; de Herder, WW; de Rijke, YB; Korevaar, TIM; Massolt, ET; Medici, M; Mulder, MT; Peeters, RP; Reiners, C; Roeters van Lennep, JE; Verburg, FA; Visser, TJ, 2018) |
| "Hypothyroidism is a common endocrine disorder, which generally results from diminished normal circulating concentrations of serum thyroxine (fT4) and triiodothyronine (fT3)." | ( Aksakal, N; Arici, M; Ozcinar, B; Ozhan, G; Oztas, E; Yanar, F, 2018) |
| "Hypothyroidism is often associated with psychiatric disorders such as depression." | ( Araujo, SM; Bertolazi, BS; Bortolotto, VC; de Almeida, FP; de Freitas Couto, S; de Paula, MT; Jesse, CR; Meichtry, LB; Pinheiro, FC; Poetini, MR; Prigol, M, 2018) |
| "Currently, hypothyroidism is usually treated only with drugs; patients are never told that they could regulate their levels of iodine with dietary recommendations in a complementary way." | ( Cepeda, A; Franco, C; Lopez, Y; Vázquez, B, 2018) |
| "Hypothyroidism is relatively common, occurring in approximately 5% of the general US population aged ≥12 years." | ( Espaillat, R; Hennessey, JV, 2018) |
| "Primary hypothyroidism is a common endocrine disorder, more so in an increasing UK ageing population." | ( Hickey, J; Hrisos, S; Ingoe, LE; Pearce, S; Rapley, T; Razvi, S; Wilkes, S, 2018) |
| "Although overt hypothyroidism is rare (prevalence of 0,3 %), levothyroxine has become the most prescribed medication in the US, while its indications are still debated." | ( Aubert, CE; Baumgartner, C; Blum, MR; Collet, TH; Feller, M; Rodondi, N; Stettler, C; Sykiotis, GP, 2018) |
| "Hypothyroidism is one of the most common hormone deficiencies in adults." | ( de Carvalho, GA; Graf, H; Mesa Junior, C; Paz-Filho, G, 2018) |
| "Hypothyroidism is a common disorder that is associated with psychological disturbances such as dementia, depression, and psychomotor disorders." | ( Fukunaga, K; Husain, N; Shinoda, Y; Yabuki, Y, 2018) |
| "Hypothyroidism is one of the most prevalent diseases in pregnancy, but there is no consensus about its management in pregnant women." | ( Aristides, SMA; de Carvalho, HC; Demarchi, IG; Günther, LSA; Lopes, LCB; Santos, TDS; Shinohara, DR; Teixeira, JJV, 2018) |
| "Hypothyroidism is a common endocrinological disorder in which CEA levels can rise, and is sometimes overlooked as a diagnosis in the absence of typical symptoms or thyroid enlargement." | ( Nomoto, H; Sekizaki, T; Yamamoto, C, 2018) |
| "Hypothyroidism is relatively rare etiology of serositis with effusion, but massive pleural effusion is very unusual." | ( Jo, YS; Lee, JH; Park, M; Park, MJ, 2018) |
| "Hypothyroidism is a condition that becomes more prevalent with age." | ( Blum, D; Chaalal, A; Enderlin, V; Laroche, S; Poirier, R, 2019) |
| "Although hypothyroidism is associated with many comorbidities, the evidence for its association with all-cause mortality in older adults is limited." | ( Huang, HK; Kao, SL; Wang, JH, 2018) |
| "Most patients with hypothyroidism are unable to comply with the proper timings of levothyroxine (LT4) administration." | ( Mahar, SA; Mawani, M; Sheikh, A, 2018) |
| "Radiation-induced hypothyroidism is the most common thyroid disorder after radiotherapy in nasopharyngeal carcinoma (NPC) patients." | ( Gao, X; He, B; Lin, Z; Tam, SY; Wang, D; Wu, VWC; Yang, Z, 2018) |
| "Hypothyroidism is a common clinical problem that is successfully treated with hormone substitutes in the form of levothyroxine (LT4)." | ( Bakula, M; Dumić, J; Jakupović, L; Klobučar, SM; Liberati-Čizmek, AM; Lončar, JV; Lucijanić, M; Lucijanić, T; Marušić, S; Matić, T; Rahelić, D; Romić, Ž; Skelin, M, 2018) |
| "Hypothyroidism is associated with an increased bleeding risk, whereas hyperthyroidism leads to an increased risk of venous thrombosis." | ( Elbers, LPB; Gerdes, VEA; Squizzato, A, 2018) |
| "Hypothyroidism is prevalent in morbidly obese patients and may improve after a weight reduction surgery." | ( Avital, S; Berkovich, L; Inbar, R; Keidar, A; Kent, I; Rudnicki, Y; Slavin, M; Tiomkin, V, 2018) |
| "Hypothyroidism is a chronic and debilitating disease that is estimated to affect 3% of the general population." | ( Alomari, M; Basit, AW; Dodoo, CC; Gaisford, S; Trenfield, SJ; Velaga, S; Vuddanda, PR, 2018) |
| "BACKGROUND Hypothyroidism is the second most common endocrine disorder following diabetes." | ( As'ad, A; Bakkar, S; Obeidat, KA; Saadeh, NA, 2018) |
| "Clinical hyper and hypothyroidism are associated with a risk for depression." | ( Hong, JW; Kim, DJ; Noh, JH, 2018) |
| "Hypothyroidism is associated with an increase in serum cortisol level while the long-term activity of hypothalamic-pituitary-adrenal (HPA) axis in hypothyroid, and subclinical hypothyroid (SCH) subjects has not been studied." | ( Abdulateef, DS; Mahwi, TO, 2019) |
| "Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further." | ( Blum, MR; Dekkers, OM; Den Elzen, WPJ; Du Puy, RS; Ford, I; Gussekloo, J; Jukema, JW; Kean, S; Kearney, PM; Messow, CM; Mooijaart, SP; Peeters, RP; Poortvliet, RKE; Postmus, I; Rodondi, N; Smit, JWA; Stott, DJ; van Munster, BC; Watt, T; Westendorp, RGJ; Wolffenbuttel, BHR, 2018) |
| "Hypothyroidism is commonly associated with sinus bradycardia, low QRS complexes, prolonged QT interval and conduction blocks but rarely may cause arrhythmias." | ( Mak, WW; Mohamed Badrulnizam, LB; Raja Nurazni, RA, 2018) |
| "Hypothyroidism is an endocrine disorder due to decreased thyroid hormone production." | ( Elgoly, AHM; Wahman, LF; Yousef, MH, 2018) |
| "Maternal hypothyroidism is associated with several pregnancy and perinatal complications, but consistent LT4 use may reduce many of the risks." | ( Gissler, M; Hartikainen, AL; Lahesmaa-Korpinen, AM; Männistö, T; Suvanto, E; Turunen, S; Vääräsmäki, M, 2019) |
| "Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA)." | ( Anothaisintawee, T; Chailurkit, LO; Chirakalwasan, N; Manodpitipong, A; Nimitphong, H; Pinyopodjanard, S; Reutrakul, S; Saetang, S; Siwasaranond, N; Sriphrapradang, C; Suntornlohanakul, O, 2019) |
| "Hypothyroidism is a frequent endocrine disorder with common symptoms of increased cold sensitivity and unintended weight gain, indicating changes in energy expenditure (EE) and response to cold exposure." | ( Betz, MJ; Christ-Crain, M; Gashi, G; Loeliger, R; Maushart, CI, 2019) |
| "Central hypothyroidism is uncommon and may be associated with other congenital syndromes and deficiencies of other pituitary hormones." | ( Leung, AAC; Leung, AKC, 2019) |
| "While hypothyroidism is known to result in adverse cardiac effects, the molecular mechanisms that modulate TH signaling are not completely understood." | ( Dewey, CM; Grueter, CE; Hall, DD; Minerath, RA, 2019) |
| "Subclinical hypothyroidism is a common condition in patients with heart failure and is defined as elevated serum thyroid hormone (TSH) with normal circulating free thyroxine (FT4)." | ( An, SM; Chen, J; Liu, YP; Tang, YD; Tian, J; Wang, JJ; Wang, SY; Wang, WY; Yang, M; Zhang, K; Zhang, X; Zhao, Y; Zheng, JL, 2019) |
| "Hypothyroidism is associated with memory impairments." | ( Brabant, G; Göbel, A; Goerges, R; Göttlich, M; Heldmann, M; Münte, TF; Nieberding, R; Sartorius, A, 2019) |
| "Overt hypothyroidism is diagnosed by a decreased FT4, while patients with a normal FT4 are considered to have subclinical disease." | ( Sullivan, SA, 2019) |
| "Sunitinib-induced hypothyroidism is a common side-effect of the drug." | ( Chrisofos, M; Kontzoglou, K; Papazisis, K; Safioleas, M; Sdrolia, A; Vasileiadis, T, 2019) |
| "Hypothyroidism is a chronic illness with simple treatment, yet non-compliance is common." | ( Al-Hajje, A; Awada, S; Bawab, W; El Helou, S; Hallit, S; Rachidi, S; Salameh, P; Zein, S, 2019) |
| "Hypothyroidism is also a frequent complication in patients treated with lenvatinib." | ( Abe, M; Hiasa, Y; Hiraoka, A; Hirooka, M; Imai, Y; Joko, K; Koizumi, Y; Matsuura, B; Michitaka, K; Miyake, T; Ochi, H; Tanaka, T; Watanabe, T; Yoshida, O; Yukimoto, A, 2019) |
| "Although hypothyroidism is a common endocrine abnormality, its clinical significance in TAFRO syndrome remains unclear." | ( Nohgawa, M; Oka, S; Ono, K, 2019) |
| "Hypothyroidism is one of the adverse drug reactions that associated with Multidrug Resistant Tuberculosis (MDR-TB) medications." | ( Holakouie-Naieni, K; Lejisa, T; Mansournia, MA; Mola, M; Tesfaye, E; Tola, HH; Yaseri, M, 2019) |
| "Subclinical hypothyroidism is diagnosed by an elevated thyroid-stimulating hormone concentration with a normal concentration of free thyroxine hormone." | ( Agrawal, R; Akhtar, MA; Brown, J; Craciunas, L; Sajjad, Y, 2019) |
| "Subclinical hypothyroidism is most often caused by autoimmune (Hashimoto) thyroiditis." | ( Biondi, B; Cappola, AR; Cooper, DS, 2019) |
| "Subclinical hypothyroidism is common and most individuals can be observed without treatment." | ( Biondi, B; Cappola, AR; Cooper, DS, 2019) |
| "Hypothyroidism is one of the most common endocrine disorders, affecting as much as 10% of the global population." | ( Hennessey, JV; Mateo, RCI, 2019) |
| "Hypothyroidism is one of the common endocrine complications described in patients with β-thalassemia major (β-TM)." | ( Alquobaili, F; Kabalan, Y; Mukhalalaty, Y; Yassouf, MY, 2019) |
| "Hyper and hypothyroidism are associated with large changes in brain oxidative stress." | ( Bandegi, AR; Pakdel, A; Salami, M; Sameni, HR; Vafaei, AA, 2019) |
| "Fetal goitrous hypothyroidism is a rare entity and is caused mainly by maternal treatment of Graves' disease (GD)." | ( Campos, RA; Castro, JM; Machado, CM; Oliveira, MJ, 2019) |
| "Hypothyroidism is a common medical disorder which results in many metabolic effects, such as dyslipidemia, hypertension, accelerated atherosclerosis, and coronary artery disease." | ( Lokuliyana, PN; Weerakkody, RM, 2019) |
| "Hypothyroidism is diagnosed biochemically, being overt primary hypothyroidism defined as serum thyroid-stimulating hormone (TSH) concentrations above and thyroxine concentrations below the normal reference range." | ( Carlé, A; Chiovato, L; Magri, F, 2019) |
| "Hypothyroidism is the most common endocrine disease in dogs and has been shown to have a hereditary nature in many breeds." | ( Cecere, J; Panciera, D; Purswell, B, 2020) |
| "Hypothyroidism is the most frequent pregnancy-related thyroid dysfunction, including overt and subclinical hypothyroidism." | ( Shan, Z; Teng, W, 2019) |
| "Hypothyroidism is more common among older subjects in comparison to the younger counterparts." | ( Basile, F; Biondi, A; Borzì, AM; Vacante, M, 2020) |
| "Hypothyroidism is an autoimmune disease associated with underactive thyroid gland." | ( Gümrükçü, S; Kök, FN; Kutlu Kaya, C; Saraç, AS, 2020) |
| "Hypothyroidism is commonly associated with substantial adverse impacts on human health, and polybrominated diphenyl ether (PBDE), a kind of classic thyroid hormone disruptor, was speculated to be a potential environmental factor, but its effect on thyroxine metabolism has received little attention." | ( Chen, C; Chen, H; Gong, X; Hu, Y; Ji, M; Shen, J; Wang, C; Wang, SL; Xia, R; Yu, Y; Zhang, Z; Zhu, J, 2020) |
| "Treatment for hypothyroidism is becoming more frequent." | ( Calissendorff, J; Falhammar, H, 2020) |
| "Hypothyroidism is a common endocrine disorder that predominantly occurs in females." | ( Bajic, VB; Essack, MM; Gluvic, ZM; Isenovic, ER; Obradovic, MM; Radak, DJ; Sudar-Milovanovic, EM; Takashi, G; Zafirovic, SS, 2020) |
| "Amiodarone induced hypothyroidism is treated with levothyroxine and amiodarone taking is not interrupted." | ( Brutvan, T; Ježková, J; Krátký, J, 2020) |
| "Primary hypothyroidism is one of the late complications that can occur after radiation therapy for malignant tumors in the head and neck region." | ( Balentová, S; Ďuroška, M; Hajtmanová, E; Kinclová, I; Kozlíková, K; Matula, P; Muríň, P, 2020) |
| "Primary hypothyroidism is characterized by loss of thyroxine feedback inhibition and overproduction of thyrotropin-releasing hormone, which might result in reactive pituitary hyperplasia." | ( Du, J; Gao, S; Hu, S; Ji, H; Jin, J; Yan, X, 2020) |
| "Hypothyroidism is a common adverse event of lenvatinib therapy for hepatocellular carcinoma (HCC), whereas thyrotoxicosis has rarely been reported in clinical trials." | ( Enomoto, M; Fujii, H; Hagihara, A; Inaba, M; Kawada, N; Kotani, K; Nagata, Y; Suoh, M; Tamori, A, 2020) |
| "Adult‑onset hypothyroidism is associated with an increase in cell atrophy of the hippocampal pyramidal neurons." | ( Alva-Sánchez, C; Martínez-Salazar, C; Pacheco-Rosado, J; Villanueva, I, 2020) |
| "Hypothyroidism is a common but often unrecognized condition associated with significant morbidity in the older adult population." | ( Espaillat, R; Hepp, Z; Lage, MJ; Vora, J, 2020) |
| "Hypothyroidism is associated with a lower metabolic rate, impaired glucose tolerance, and increased responsiveness of sympathetic nervous system to glucose ingestion." | ( Assis, GG; Kozacz, A; Sanocka, U; Ziemba, AW, 2021) |
| "Hypothyroidism is frequently found to be associated with morbid obesity." | ( Aggarwal, S; Gupta, Y; Khan, WF; Singla, V, 2020) |
| "Hypothyroidism is one of the most common chronic endocrine conditions." | ( Abdelhamid, E; Adel, A; Al Ali, N; Al Juhani, NR; Al Mourad, M; Alamri, FA; Alhazmi, AS; Almaghamsy, AM; Alsefri, S; Alzahrani, AS; Alzahrani, MDA; El Bahtimy, H; Hafez, K; Hussein, WI; Ismail, M; Saeedi, MY, 2020) |
| "Consumptive hypothyroidism is a rare paraneoplastic syndrome characterized by excessive inactivation of the thyroid hormones due to increased type 3 iodothyronine deiodinase activity of tumors." | ( Hong, KT; Kim, GB; Kim, YH; Ko, JS; Lee, YA; Lee, YJ; Shin, CH, 2020) |
| "Central hypothyroidism is a rare cause of hypothyroidism, consequence of various disorders affecting pituitary (secondary) or hypothalamus (tertiary hypothyroidism)." | ( Martirosian, NS; Petunina, NA; Trukhina, LV, 2019) |
| "Overt hypothyroidism is a common endocrine disorder affecting 1-2% of women of reproductive age." | ( Chan, SY; Li, SW, 2020) |
| "Hypothyroidism is a common condition in which the thyroid gland provides insufficient amounts of thyroid hormone for the needs of peripheral tissues." | ( McDermott, MT, 2020) |
| "Hypothyroidism is one of the most common endocrine disorders encountered by primary care physicians and endocrinologists." | ( Gupta, S; Hennessey, JV; Ritter, MJ, 2020) |
| "Hypothyroidism is a clinical syndrome caused by thyroid hormone deficiency due to reduced production, deranged distribution, or lack of effects of thyroid hormone." | ( Alam, MA; Ansari, S; Quamri, MA; Sofi, G, 2020) |
| "Hypothyroidism is associated with a wide array of medical, neurological, and psychiatric symptoms." | ( Castro-Revoredo, I; Kaplan, JL, 2020) |
| "Hypothyroidism is a thyroid dysfunction characterized by hypometabolism of the gland, with reduced or physiologically normal T3 and T4 serum levels, and high TSH level." | ( Albuquerque, YML; Silva, WED; Souza, FAL; Teixeira, ÁAC; Teixeira, VW, 2020) |
| "Hypothyroidism is the most common thyroid disorder, affects women more frequently, and incidence increases with age." | ( Alam, MA; Quamri, MA, 2020) |
| "Subclinical hypothyroidism is a biochemical condition defined by elevated serum thyroid-stimulating hormone levels in the setting of normal levels of the peripheral thyroid hormones, thyroxine and triiodothyronine." | ( Leung, AM; Sue, LY, 2020) |
| "Hypothyroidism is a common endocrine disorder affecting 3-15% of the adult population in subclinical form and 0." | ( Gietka-Czernel, M; Hubalewska-Dydejczyk, A; Kos-Kudła, B; Lewiński, A; Ruchała, M; Syrenicz, A; Zgliczyński, W, 2020) |
| "Hypothyroidism is associated with reversible decline in kidney function as measured by estimated glomerular filtration rate (eGFR)." | ( Chandrasekaran, A; Gondil, VS; Gupta, KL; Jha, V; Kohli, HS; Kumar, V; Ramachandran, R; Rastogi, A; Rathi, M; Sood, A; Yadav, AK, 2021) |
| "Hypothyroidism is believed to be associated with dyslipidemia and is considered a risk factor for the development of atherosclerotic cardiovascular diseases (ASCVD)." | ( Alsaleem, SA; Alsamghan, AS; Alzahrani, MAS; Mallick, AK; Patel, A; Sheweita, SA, 2020) |
| "Hypothyroidism is the most frequent thyroid dysfunction." | ( , 2021) |
| "The incidence of hypothyroidism is not expected to differ by socioeconomic factors." | ( Andersen, CL; Grand, MK; Jacobsen, RK; Jørgensen, T; Kårhus, LL; Knudsen, N; Kriegbaum, M; Lind, B; Linneberg, A; Medici, BB; Møllehave, LT; Nygaard, B; Pedersen, IB; Ravn-Haren, G; Siersma, V; Skaaby, T; Thuesen, BH, 2021) |
| "Hypothyroidism is one of the most commonly diagnosed endocrine disease in dogs." | ( Cerón, JJ; González-Arostegui, LG; Horvatić, A; Mrljak, V; Muñoz-Prieto, A; Rubić, I; Tvarijonaviciute, A, 2021) |
| "Hypothyroidism is diagnosed on the basis of laboratory tests because of the lack of specificity of the typical clinical manifestations." | ( Aljenaee, K; Dannan, R; Hajji, S, 2021) |
| "Hypothyroidism is an uncommon side effect of pomalidomide." | ( Qureshi, A; Rhee, JH, 2021) |
| "Hypothyroidism is prevalent, mainly found in women, and increasing with age." | ( Ellegård, L; Krantz, E; Landin-Wilhelmsen, K; Trimpou, P, 2021) |
| "Hypothyroidism is a common pathological condition characterized by insufficient activity of the thyroid hormones (THs), thyroxine (T4), and 3,5,3'-triiodothyronine (T3), in the whole body or in specific tissues." | ( Appelbaum, L; Blitz, E; Guenther, S; Kubota, Y; Lerer-Goldshtein, T; Matsuda, H; Morikawa, T; Stainier, DYR; Zada, D, 2021) |
| "Subclinical hypothyroidism is related with increased risk of cardiovascular diseases." | ( Gonulalan, G; Tanrıkulu, Y, 2022) |
| "Subclinical hypothyroidism is associated with adverse obstetric and offspring outcomes." | ( Corsello, A; Locantore, P; Policola, C; Pontecorvi, A, 2021) |
| "Subclinical hypothyroidism is related with cardiac diseases and oxidative stress, but the exact mechanisms underlying these associations are not clear yet." | ( Fırlatan, B; Gürlek, A; Lay, İ; Oğuz, SH; Samadi, A; Savaş, M; Ünlütürk, U; Yüce, D, 2021) |
| "Although hypothyroidism is associated with various comorbidities, its relationship with increased all-cause mortality remains controversial." | ( Chung, JH; Seo, GH; Sohn, SY, 2021) |
| "Hypothyroidism is one of the most common endocrinopathies in dogs." | ( Mischke, R; Rieder, J; Strey, S, 2021) |
| "Hypothyroidism is the most common disorder arising from hormone deficiency." | ( Alam, MA; Haider, N; Quamri, MA, 2021) |
| "Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed." | ( Jonklaas, J, 2022) |
| "Hypothyroidism is a common condition with a prevalence that varies according to local dietary iodine availability, gender and age." | ( Gottwald-Hostalek, U; Schulte, B, 2022) |
| "Hypothyroidism is a condition that affects multiple systems, including the central nervous system, causing, for example, cognitive deficits closely related to Alzheimer's disease." | ( Araujo, SM; Boeira, SP; Bortolotto, VC; Fronza, MG; Meichtry, LB; Pinheiro, FC; Poetini, MR; Prigol, M; Savegnago, L, 2021) |
| "Hypothyroidism is an endocrine disorder whose management raises many challenges in clinical practice." | ( Concepción-Urteaga, LA; Concepción-Zavaleta, MJ; Deutz Gómez-Condori, DC; Herrera-Cabezas, RG; Ildefonso-Najarro, SP; Paz-Ibarra, JL; Rivera-Fabián, KE; Valdivia Fernández-Dávila, FR, 2021) |
| "Hypothyroidism is common after hemithyroidectomy, and almost half of the patients will need thyroid hormone replacement." | ( Cao, Z; Liu, R; Liu, Z; Wu, M; Xu, X, 2022) |
| "Hypothyroidism is the most common endocrine disorder worldwide." | ( Kaushik, P; Kumar Singh, N; Kumari, M; Suri, A, 2022) |
| "Subclinical hypothyroidism is known to increase the risk of cardiovascular diseases and mortality." | ( Chen, S; Gao, B; Guo, X; Jiang, Y; Kang, X; Li, X; Liu, Y; Tao, L; Wang, W; Wu, Z; Zhang, H; Zhang, J; Zhao, Y; Zhou, D, 2022) |
| "Subclinical hypothyroidism is associated with incident metabolic syndrome in young men." | ( Chen, S; Gao, B; Guo, X; Jiang, Y; Kang, X; Li, X; Liu, Y; Tao, L; Wang, W; Wu, Z; Zhang, H; Zhang, J; Zhao, Y; Zhou, D, 2022) |
| "Hypothyroidism is the second most common endocrinological disease during pregnancy, with percentages that can range between 3." | ( Galván, L; Orós, M; Ortega, M; Perejón, D; Serna, MC; Siscart, J, 2022) |
| "Hypothyroidism is caused by deficient thyroid hormone production secondary to autoimmune disease or insufficient iodine consumption or as a complication of hyperthyroidism management." | ( Adams, CS; Bragg, S; Christian, N; Rhodes, MA, 2022) |
| "Hypothyroidism is a frequently occurring side effect in patients under treatment with immune checkpoint inhibitors (ICIs)." | ( Beyens, MMJ; Forceville, K; Th B Twickler, M; Vandenbroucke, E; Verelst, FR, 2022) |
| "Hence, subclinical hypothyroidism is essentially a laboratory diagnosis." | ( Mb, V; S, S, 2022) |
| "Iatrogenic hypothyroidism is a recognised complication of all of the treatment options for hyperthyroidism, and increases the risk of azotaemia." | ( Aguiar, J; Geddes, R, 2022) |
| "Hypothyroidism is a common adverse event of various anticancer treatment modalities, constituting a notable paradigm of the integration of the endocrine perspective into precision oncology." | ( Deligiorgi, MV; Trafalis, DT, 2022) |
| "Hypothyroidism is one of the most common endocrine disorders linked to various systemic diseases ranging from obesity to cancers." | ( Jyothi, N; Nair, PMK, 2021) |
| "Autoimmune hypothyroidism is frequently associated with obesity, it is usually progressive and needs replacement treatment with L-thyroxine." | ( Basolo, A; Bechi Genzano, S; Ceccarini, G; Chiovato, L; Fierabracci, P; Rotondi, M; Salvetti, G; Santini, F; Scartabelli, G; Sotgia, G, 2022) |
| "Consumptive hypothyroidism is a rare complication of IHH, but suggestive of multifocal/diffuse subtypes." | ( Alves, I; Coelho, J; Do Bom-Sucesso, M; Morais, CG; Vilares, AT, 2023) |
| "Hypothyroidism is a systemic hypometabolic syndrome caused by the thyroxine resistance or a reduction in its extent." | ( Chen, D; Chen, X; Huang, R; Li, L; Luo, L; Wang, H, 2022) |
| "Management of hypothyroidism is controversial because of medication cost pressures and scientific uncertainty on how to address treatment dissatisfaction experienced by some patients." | ( Attanasio, R; Field, BCT; Hegedüs, L; Nagy, EV; Negro, R; Papini, E; Perros, P; Younes, YR, 2023) |
| "Maternal hypothyroidism is associated with pre-eclampsia and intrauterine growth restriction, gestational diseases involving oxidative stress (OS) and endoplasmic reticulum stress (ERS) in the placenta." | ( Barbosa, EM; de Freitas, GJC; de Lavor, MSL; de Macêdo, IO; de Oliveira, LS; Dos Anjos Cordeiro, JM; Santos, BR; Santos, DA; Santos, EO; Santos, LC; Silva, JF, 2022) |
| "Hypothyroidism is the most commonly diagnosed endocrine disorder in dogs." | ( Cerón, JJ; González-Arostegui, LG; Gotić, J; Mrljak, V; Muñoz-Prieto, A; Rafaj, RB; Rubić, I; Rubio, CP; Tvarijonaviciute, A, 2022) |
| "On the other hand, hypothyroidism is a common disease that causes cognitive disorders." | ( Beheshti, F; Darroudi, M; Hashemzadeh, A; Hojjati Fard, F; Hosseini, M; Marefati, N; Sabzi, F; Vafaee, F, 2022) |
| "Hypothyroidism is associated with an increased risk of cardiovascular disease and enhanced susceptibility to arrhythmias." | ( Costa, AD; Cruz, JS; Durço, AO; Joviano-Santos, JV; Marques, LP; Rhana, P; Roman-Campos, D; Santos-Miranda, A; Souza, DS; Vasconcelos, CML, 2022) |
| "Adult-onset hypothyroidism is associated with learning and cognitive dysfunctions, which may be related to alterations in synaptic plasticity." | ( Chamas, L; Clerget-Froidevaux, MS; Enderlin, V; Poirier, R; Seugnet, I, 2022) |
| "Clinical hypothyroidism is defined by the inadequate production of thyroid hormone from the thyroid gland to maintain normal organ system functions." | ( Ettleson, MD; Papaleontiou, M, 2022) |
| "Gestational hypothyroidism is a prevalent disorder in pregnant women and also impairs fetal development with relevant outcomes." | ( Batista, TH; Dos Anjos-Garcia, T; Giusti-Paiva, A; Hipólito, LTM; Vilela, FC, 2023) |
| "Gestational hypothyroidism is a prevalent disorder in pregnant women and also impairs fetal development with relevant outcomes." | ( Batista, TH; Dos Anjos-Garcia, T; Giusti-Paiva, A; Hipólito, LTM; Vilela, FC, 2023) |
| "Hypothyroidism is a commonly encountered endocrine disorder presenting in various clinical settings." | ( Dinkar, A; Kumar, K; Kumar, N; Singh, J, 2023) |
| "Hypothyroidism is a commonly encountered endocrine disorder presenting in various clinical settings." | ( Dinkar, A; Kumar, K; Kumar, N; Singh, J, 2023) |
| "Hypothyroidism is an important reversible cause of acute kidney injury (AKI), acting through various mechanisms, including rhabdomyolysis, metabolic, and systemic effects." | ( Bandi, VK; Narilla, NSSH; Ramineni, S; Yarlagadda, S, 2023) |
| "Hypothyroidism is a common clinical condition of thyroid hormone deficiency and is frequently seen in women." | ( Dawadi, P; Kadel, M; Khadka, S; Yadav, GK, 2022) |
| "Subclinical hypothyroidism is common with increasing age and has been associated with reduced muscle strength." | ( Aeberli, D; Aujesky, D; Bauer, DC; Büchi, AE; Chocano-Bedoya, P; Collet, TH; Feller, M; Gussekloo, J; Janett-Pellegri, C; Kearney, PM; Mc Carthy, VJC; Mooijaart, S; Moutzouri, E; Netzer, S; Poortvliet, RKE; Quinn, TJ; Rodondi, N; Rodriguez, EG; Westendorp, R; Wildisen, L, 2023) |
| "Hypothyroidism is one of the common endocrine diseases, and its incidence is increasing year by year." | ( Guo, B; Jia, X; Liang, J; Liao, B; Lu, J; Sun, R; Zhang, T, 2023) |
| "Subclinical hypothyroidism is an independent predictor of CKD in the general population." | ( Byun, DW; Kim, HJ; Park, HK; Park, SJ; Suh, K; Yoo, MH, 2023) |
| "Hypothyroidism is a common endocrine disease in the world that causes morbidity and mortality due to its association with metabolic diseases, especially in old age, and longterm treatment with levothyroxine causes many side effects for patients." | ( Javidi, N; Khorasani, ZM; Niroumand, S; Salari, R; Yousefi, M, 2023) |
| "Hypothyroidism is a common condition, and numerous studies have been published over the last decade to assess the potential risks associated with this disorder when inappropriately treated." | ( Biondi, B; Celi, FS; McAninch, EA, 2023) |
| "Acquired hypothyroidism is generally also referred to as juvenile hypothyroidism." | ( Bhattacharyya, SS; Singh, A, 2023) |
| "Acquired hypothyroidism is the most common thyroid disease in paediatric patients and in iodine-replete areas mainly due to autoimmune thyroiditis (AIT)." | ( Lauridsen, MB; Leunbach, TL; Nærå, RW, 2023) |
| "Hypothyroidism is clinically characterized by a decrease in levels of the circulating thyroid hormones namely thyroxine and triiodothyronine." | ( Abdel Rahman, AM; Alfadda, AA; Almalki, RH; Benabdelkamel, H; Dahabiyeh, LA; Jaber, MA; Masood, A; Musambil, M, 2023) |
| "Hypothyroidism is a common endocrine disorder and requires lifelong treatment." | ( Ara, S; Islam, MN; Moni, SY; Rahman, FB; Sultana, Z; Zubery, MH, 2023) |
| "Hypothyroidism is the most common complication of hemithyroidectomy for thyroid nodules." | ( Le Pennec, R; Leclère, JC; Leclère, JM; Mahéo, C; Marianowski, R; Potard, G; Prévot, J; Roudaut, N; Thuillier, P, 2023) |
| "Hypothyroidism is the commonest endocrine disorder of pregnancy, with known adverse feto-maternal outcomes." | ( Bhandari, N; Chaudhary, R; Chowdhury, R; Dang, A; Dewan, R; Dhabhai, N; Kaur, J; Mittal, P; Taneja, S; Virmani, A, 2023) |
| "Hypothyroidism is one of the most important complications which occur due to urinary loss of protein bound thyroid hormones, such as thyroxin binding globulin, transthyretin and albumin." | ( Akter, MM; Ali, MA; Avik, AD; Das, K; Dipu, MR; Kabir, MR; Momo, FR; Noshin, N; Paul, A; Sadika, S, 2023) |
| "Hypothyroidism is associated with adverse cardiovascular consequences, including heart failure." | ( Bashir, MT; Currier, JW; Ebrahimi, R; Guo, R; Inoue, K; Lee, ML; Leung, AM; Neverova, NV, 2023) |
| Excerpt | Reference |
|---|
| "Group II (18 patients) received no treatment." | ( Beck, JS; Crooks, J; Gunn, A; Isles, TE; Wilkin, TJ, 1979) |
| "The importance of diagnosing and treating primary hypothyroidism in adult patients with Down's syndrome is stressed even in the absence of thyroid antibodies." | ( Jewell, RC; Stein, GR, 1979) |
| "In the treatment of hypothyroidism, the cholesterol-lowering and metabolic rate-stimulating effects of dextrothyroxine do not appear to be dissociated." | ( Ellefson, RD; Elveback, LR; Gorman, CA; Jiang, NS, 1979) |
| "The study also indicates that treatment of hypothyroidism may occasionally not be lifelong." | ( McDougall, IR; Sung, LC, 1978) |
| "The importance of early treatment of hypothyroidism in the neonatal period to prevent brain damage is emphasized." | ( Jackson, IM, 1976) |
| "These data indicate that, during the treatment of hypothyroidism with T4, 1) normal basal TSH correlates better with normal serum T4 and T3 than with normal T4 alone, 2) the response of TSH to TRH is supranormal in patients with subnormal T3 levels, in spite of normal basal TSH and T4, and 3) the calculated maintenance dose of T4, which is associated with a normal TRH response, is 2." | ( Ikeda, H; Imai, Y; Kuzuya, N; Maeda, M; Masuyama, Y, 1976) |
| "A 34-year-old woman with longstanding untreated thyroprivic hypothyroidism and pituitary enlargement is reported here in whom visual failure coincided with thyroid hormone replacement." | ( Breidahl, HD; Essex, WB; Murray, RM; Stockigt, JR; West, RH, 1976) |
| "Various regimens of treatment for hypothyroidism are discussed with recommendations for avoiding this potentially hazardous complication of therapy." | ( Penfold, JL; Simpson, DA, 1975) |
| "With treatment of the hypothyroidism alone there was a statistically significant improvement in facility of outflow, intraocular pressure and Po/C (p < 0." | ( Allen, LH; Smith, KD; Tevaarwerk, GJ, 1992) |
| "The subjects consisted of cases of untreated hypothyroidism and chronic thyroiditis (CT) and euthyroid controls who were healthy people or had non-thyroidal disorders such as diabetes mellitus or hypertension." | ( Hirooka, Y; Ishizuki, Y; Murata, Y, 1992) |
| "The pattern of growth in girls with treated hypothyroidism was abnormal as growth continued after menarche, at a time when normal girls have almost stopped growing." | ( Grant, DB; Pantsiouou, S; Preece, MA; Stanhope, R; Uruena, M, 1991) |
| "When treating hypothyroidism, psychiatric issues may result in noncompliance with levothyroxine therapy." | ( Ain, KB; Fein, HG; Refetoff, S; Weintraub, BD, 1991) |
| "The course of untreated mild hypothyroidism was followed in 67 nursing home residents (mean age 78 years)." | ( Drinka, PJ; Langer, EH; Nolten, WE; Voeks, SK, 1991) |
| "The patients treated for hypothyroidism had lost an insignificant amount of weight 12 months after starting therapy--mean change was -0." | ( Gunn, A; Jung, RT; Pears, J, 1990) |
| "Finally the potential problems in treating hypothyroidism in the elderly are discussed in regard to dosage requirements and the need to avoid subclinical hypothyroidism by using the ultrasensitive TSH assay." | ( Griffin, JE, 1990) |
| "In 139 patients treated for hypothyroidism by thyroxine replacement there was a highly significant correlation (P less than 0." | ( Elder, J; McLelland, A; O'Reilly, DS; Packard, CJ; Series, JJ; Shepherd, J, 1990) |
| "In the untreated hypothyroidism, apo B, C-II, C-III and E levels were significantly elevated compared to the controls, and these changes in apolipoproteins except apo C-II were restored after treatment." | ( Oribe, H, 1989) |
| "Eleven patients with treated hypothyroidism were investigated to examine the effects of time on their thyroid function tests." | ( Croft, DN; Mitchell, D; Pennell, DJ; Sturgess, I; Thomas, SH, 1989) |
| "During the follow-up of 224 cases of treated hypothyroidism, 14 clinically euthyroid patients were found to have elevated serum thyrotrophin and normal total thyroxine concentrations." | ( Howel-Evans, W; McClelland, P; Stott, A, 1989) |
| "Fasting C-peptide was reduced in untreated hypothyroidism (0." | ( Beer, SF; Hales, CN; Parr, JH; Temple, RC, 1989) |
| "Eight patients (42%) required treatment for hypothyroidism." | ( Forbath, N; Stancer, HC, 1989) |
| "We have studied 16 women with pretreatment severe hypothyroidism on constant levothyroxine therapy." | ( Faber, J; Jørgensen, B; Kirkegaard, C; Kludt, J, 1989) |
| "The results of a survey on the treatment of hypothyroidism by Dutch internists, working in different types of hospitals, are described." | ( Geelhoed-Duyvestijn, PH; Haak, A; Hermans, J; van der Heide, D, 1989) |
| "Patients with untreated hypothyroidism (10) and hyperthyroidism (10) were studied, along with normal subjects (10)." | ( Brent, GA; Canessa, M; Dluhy, RG, 1989) |
| "Undiagnosed and untreated congenital hypothyroidism will result in un-toward consequences, including mental retardation and other significant neurologic sequelae." | ( LaFranchi, S, 1987) |
| "In untreated secondary hypothyroidism TSH was not always undetectable." | ( Askienazy, S; Milhaud, G; Piketty, ML; Talbot, JN, 1987) |
| "thyroxine as treatment for hypothyroidism." | ( Massey, JC; Smith, RN; Taylor, SA, 1970) |
| "of triiodothyronine have been used to treat patients with hypothyroidism of varied aetiology." | ( Adie, R; Kapur, M; Taylor, S, 1970) |
| "He had been treated for hypothyroidism since the age of 6." | ( Baker, GP; Oliver, RA, 1969) |
| "Nineteen patients with untreated hypothyroidism were evaluated by M-mode echocardiography." | ( Cave, WT; Hinojosa, L; Mathew, PK; Miller, RP; Santos, AD; Wallace, WA, 1980) |
| "Primary hyperparathyroidism masked by untreated hypothyroidism was first noted by Kissin and Bakst in 1947; since then there has been only a single case reported." | ( Calandra, DB; Lawrence, AM; Paloyan, E; Shah, K, 1984) |
| "In untreated hyper- and hypothyroidism, restoration to euthyroidism by treatment was uniformly accompanied by a normalization of serum TBPA and TBG levels." | ( Hachiya, T; Ijichi, H; Ishida, M; Kajita, Y; Miyazaki, T; Ochi, Y; Yoshimura, M, 1982) |
| "Failure to recognize and treat hypothyroidism in these pubertal patients may compromise the adult height, since skeletal maturation will proceed under the influence of sex hormones despite the presence of hypothyroidism." | ( Abbassi, V; Cancellieri, RP; Rigterink, E, 1980) |
| "Thyroid supplements should be untreated hypothyroidism." | ( Murkin, JM, 1982) |
| "Two additional infants with untreated congenital hypothyroidism has free T4 levels of 0." | ( Bayer, MF; Hintz, RL; Hopper, AO; McDougall, IR; Rosenfeld, RG; Stevenson, DK; Wilson, DM, 1982) |
| "Thirty-nine patients with untreated hypothyroidism have been examined using echocardiography for the presence of a pericardial effusion." | ( Hardisty, CA; Munro, DS; Naik, DR, 1980) |
| "After oral L-thyroxine treatment hypothyroidism disappeared rapidly." | ( Heidemann, P; Schürnbrand, P; Stubbe, P; Ulbrich, R, 1980) |
| "In untreated hypothyroidism, template bleeding time was prolonged (median 9." | ( Bregengård, C; Faber, J; Myrup, B, 1995) |
| "Avoidance of treating hypothyroidism alone when there is concomitant subclinical adrenal insufficiency is important, to avoid precipitating an adrenal crisis." | ( Adelman, HM; Alberts, WM; Cacciatore, ML; Mike, JM; Pascual, JF; Wallach, PM, 1994) |
| "However, during the initial treatment of overt hypothyroidism with levothyroxine, three studies have demonstrated short-term (6 to 12 months) 5% to 13% reductions in bone density." | ( Ross, DS, 1993) |
| "Unlike the early treatment of overt hypothyroidism, there is no short-term reduction of bone density with levothyroxine treatment of subclinical hypothyroidism in postmenopausal women." | ( Ross, DS, 1993) |
| "Long-term T4 treatment for hypothyroidism was investigated in 105 females on therapy for at least 1 year compared with 105 controls matched for age and menopausal status." | ( Betteridge, J; Daykin, J; Franklyn, JA; Holder, R; Hughes, EA; Jones, SR; Sheppard, MC, 1993) |
| "Before treatment with SLT, hypothyroidism group had higher erythrocyte sodium content ([Na]Rbc) than that of normal group." | ( Zha, LL, 1993) |
| "In 26 patients treated for hypothyroidism with thyroxine replacement there was a significant correlation between the decrease in serum cholesterol and the decrease in serum TSH (r = 0." | ( Johnston, J; McLelland, A; O'Reilly, DS, 1993) |
| "The recognition and treatment of fetal hypothyroidism are believed to be important to optimize growth and intellectual development in affected fetuses." | ( Abuhamad, AZ; Evans, AT; Fisher, DA; Pyle, PG; Slotnick, RN; Warsof, SL; Wu, SY, 1995) |
| "In developing country like ours if treatment of hypothyroidism can be started even by 6 months of age considerable brain function can be salvaged so that they can attain a self supportive life." | ( Chakrabartty, S; Kundu, R, 1996) |
| "Of five patients inadequately treated for hypothyroidism, all demonstrated angiographic evidence of coronary atherosclerosis progression." | ( O'Neill, BJ; Perk, M, 1997) |
| "In contrast, chronic methimazole treatment (hypothyroidism) decreased the BAT pad weight and the triacylglycerol content, but did not significantly change the DNA content in comparison with the control." | ( Kuroshima, A; Ohinata, H; Ohno, T; Saha, SK, 1998) |
| "(iii) Treatment of hypothyroidism resulted in a reduction in the raised plasma leptin levels." | ( Coppack, SW; Goodrick, SJ; Johnson, AB; Katz, J; Lightman, SL; Mohamed-Ali, V; Pinkney, JH, 1998) |
| "Eleven cases of undertreated hypothyroidism were found, in 9 PS patients and 2 NS patients." | ( Berlow, A; Cristian, A; Ravishankar, T; Root, B, 1999) |
| "Previously diagnosed and treated hypothyroidism was reported by 1." | ( Christiansen, E; Jorgensen, T; Knudsen, N; Perrild, H; Rasmussen, S, 1999) |
| "Pituitary hyperplasia consequent to untreated primary hypothyroidism undergoes impressive regression following thyroxine therapy." | ( Goswami, R; Kochupillai, N; Sharma, R; Tandon, N, 1999) |
| "These tests were repeated twice before treatment and after hypothyroidism had been cured." | ( Bercoff, E; Capet, C; Chassagne, P; Clerc, I; Cornier, AC; Denis, P; Doucet, J; Jego, A; Lefebvre, H; Lévesque, H; Noel, D, 2000) |
| "The complete relief of AvWS via treatment of hypothyroidism with thyroxine is the final proof of this association and causal relationship." | ( Berneman, Z; Michiels, JJ; Schroyens, W; van der Planken, M, 2001) |
| "We were interested if the treatment of hypothyroidism would affect the above factors." | ( Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A, 2001) |
| "A 48-year-old male with treated hypothyroidism underwent mechanical valve replacement for mitral valve regurgitation." | ( Inoue, Y; Kiso, I; Mori, A; Takahashi, R, 2001) |
| "The adequate treatment of hypothyroidism during gestation minimizes risks and generally, makes it possible for pregnancies to be carried to term without complications." | ( Abalovich, M; Alcaraz, G; Garcia, A; Gutierrez, S; Levalle, O; Maccallini, G, 2002) |
| "Thyroxine is the preferred treatment of hypothyroidism." | ( Haug, E, 2002) |
| "T(4) is standard treatment for hypothyroidism." | ( Bhagat, CI; Bhagat, MC; Chew, GT; Cussons, AJ; Dhaliwal, SS; Lim, EM; Shiels, L; Stuckey, BG; Walsh, JP; Ward, LC, 2003) |
| "To evaluate the benefits of treating primary hypothyroidism with levothyroxine plus liothyronine combination therapy vs levothyroxine monotherapy." | ( Clyde, PW; Getka, EJ; Harari, AE; Shakir, KM, 2003) |
| "Severe untreated hypothyroidism can lead to heart failure, psychosis, and coma." | ( Ladenson, PW; Roberts, CG, 2004) |
| "Pregnant patients with untreated hypothyroidism are at increased risk of obstetric complications." | ( Koren, G; Nava-Ocampo, AA; Soldin, OP, 2004) |
| "After 7 weeks of treatment, hypothyroidism was confirmed by determining serum free T(3) and free T(4) concentrations." | ( Bachmann, S; Bernhardt, WM; Daniel, H; Döring, F; Groneberg, DA; Klapper, M; Schmitt, R, 2005) |
| "Sparse data suggest that treatment of hypothyroidism, resulting in a return to euthyroidism, may be associated with only partial recovery of overall neurocognitive functioning." | ( Appelhof, BC; Fliers, E; Huyser, J; Schene, AH; Tijssen, JG; Wekking, EM; Wiersinga, WM, 2005) |
| "We enrolled 26 women with not-treated hypothyroidism (Group I) and 41 with not-treated simple goitre (group II)." | ( Garanty-Bogacka, B; Kosińska, A; Kosiński, B; Miazgowski, T; Syrenicz, A; Syrenicz, M, 2005) |
| "Fortunately, the treatment of feline hypothyroidism with synthetic levothyroxine is both straightforward and effective." | ( Greco, DS, 2006) |
| "We report a 55-year-old woman in whom treatment LT(4) for hypothyroidism was found related to a previously undiagnosed oligo-symptomatic lactose intolerance, an unusual association." | ( Alonso, G; Muñoz-Torres, M; Varsavsky, M, 2006) |
| "Before GH treatment, 159 patients had treated central hypothyroidism (treated group) while 84 patients were considered euthyroid (untreated group)." | ( Agha, A; Chew, SL; Drake, WM; Grossman, AB; Jenkins, PJ; Monson, JP; Perry, L; Walker, D, 2007) |
| "Chronic nicotine treatment reverses hypothyroidism-induced impairment of hippocampus-dependent spatial memory and long-term potentiation (LTP)." | ( Aleisa, AM; Alkadhi, KA; Alzoubi, KH, 2007) |
| "NO level was higher in pretreatment hypothyroidism when compared to controls." | ( Atmaca, H; Baskol, G; Baskol, M; Bayram, F; Kocer, D; Tanriverdi, F, 2007) |
| "Whether to treat subclinical hypothyroidism (SH) remains controversial." | ( Erdal, M; Gharib, H; Hasimi, A; Kutlu, M; Saglam, K; Sahin, M; Taslipinar, A; Uckaya, G; Yarpuz, MY, 2008) |
| "This study shows that thyroxin treatment reverses hypothyroidism-induced impairment of hippocampus-dependent cognition, and L-LTP, probably by restoring the levels of signaling molecule important for these processes." | ( Aleisa, AM; Alkadhi, KA; Alzoubi, KH; Gerges, NZ, 2009) |
| "The patient had been treated for hypothyroidism with levothyroxine and was noted to have an elevated total thyroxine (T4) level in the setting of a low total triiodothyronine (T3) value and a mildly elevated thyrotropin concentration." | ( Pietras, SM; Safer, JD, 2008) |
| "Those with treated hypothyroidism were older than the euthyroid group (76." | ( Barrett-Connor, E; Kramer, CK; Kritz-Silverstein, D; von Mühlen, D, 2009) |
| "Long-term treated hypothyroidism is not associated with impaired CF or depressed mood in old age." | ( Barrett-Connor, E; Kramer, CK; Kritz-Silverstein, D; von Mühlen, D, 2009) |
| "However, L-thyroxine treatment after the hypothyroidism prevented this reduction (P < 0." | ( Aydin, L; Baltaci, AK; Mogulkoc, R, 2010) |
| "In patients with stable untreated subclinical hypothyroidism the goal for analytical imprecision was met with a single analysis of serum TSH, whereas duplicate and triplicate serum measurements of fT3 and fT4 would be necessary." | ( Andersen, S; Karmisholt, J; Laurberg, P, 2010) |
| "Women with treated hypothyroidism must increase their l-T(4) in pregnancy to prevent maternal hypothyroidism, although how this should be accomplished is unclear." | ( Alexander, EK; Fawcett, R; Marqusee, E; Yassa, L, 2010) |
| "We prospectively enrolled 60 women with treated hypothyroidism seeking pregnancy." | ( Alexander, EK; Fawcett, R; Marqusee, E; Yassa, L, 2010) |
| "Myxedema coma is the extreme form of untreated hypothyroidism." | ( Ahn, HC; Ahn, JY; Kwon, HS; Sohn, YD, 2010) |
| "Accordingly, women with treated hypothyroidism need to increase their levothyroxine dose to prevent maternal hypothyroidism and the associated impaired cognitive development and increased fetal mortality." | ( Landy, HJ; Soldin, OP; Soldin, SJ; Vinks, AA; Younis, I, 2010) |
| "The standard treatment of hypothyroidism (central and primary) consists of thyroxine (T4) administration alone." | ( Casamitjana, R; Choque, L; Halperin, I; Puig-Domingo, M; Sesmilo, G; Simó, O, 2011) |
| "Ethionamide (ETH) treatment may cause hypothyroidism." | ( Hesseling, AC; Magdorf, K; Schaaf, HS; Thee, S; Willemse, M; Zöllner, EW, 2011) |
| "There is consensus on the need to treat subclinical hypothyroidism of any magnitude in pregnant women and women who are contemplating pregnancy, to decrease the risk of pregnancy complications and impaired cognitive development of the offspring." | ( Khandelwal, D; Tandon, N, 2012) |
| "Although the diagnosis and treatment of hypothyroidism is often considered simple, there are large numbers of people with this condition who are suboptimally treated." | ( Chakera, AJ; Pearce, SH; Vaidya, B, 2012) |
| "If left untreated, both hypothyroidism and hyperthyroidism are associated with adverse effects on pregnancy and fetal outcomes." | ( Sullivan, SD; Yazbeck, CF, 2012) |
| "Women with treated hypothyroidism (n=21) had significantly less implantation, clinical pregnancy, and live birth rates than euthyroid women (n=219)." | ( Demir, H; Fierro, MA; Kang, Y; Scoccia, B; Winston, NJ, 2012) |
| "The most important reasons to treat overt hypothyroidism are to relieve symptoms and avoid progression to myxedema." | ( Bensenor, IM; Lotufo, PA; Olmos, RD, 2012) |
| "Compliance to levothyroxine treatment in hypothyroidism is compromised by daily schedule, and a weekly dose may be an alternative." | ( Bornschein, A; Carvalho, GA; Graf, H; Paz-Filho, G, 2012) |
| "Unrecognised or untreated hypothyroidism during pregnancy is associated with adverse outcomes that can be ameliorated or prevented by adequate therapy with thyroxine." | ( Krysiak, R; Okopień, B, 2012) |
| "Weight decreases following treatment for hypothyroidism." | ( Pearce, EN, 2012) |
| "The preferred treatment for hypothyroidism is oral levothyroxine (LT4) ingestion, in doses that ensure a sustained state of hormonal balance." | ( Ruchała, M; Szczepanek-Parulska, E; Zybek, A, 2012) |
| "The decision to treat subclinical hypothyroidism when the serum thyrotropin is less than 10 mIU/L should be tailored to the individual patient." | ( Cobin, RH; Garber, JR; Gharib, H; Hennessey, JV; Klein, I; Mechanick, JI; Pessah-Pollack, R; Singer, PA; Woeber, KA, 2012) |
| "In summary, the successful treatment of hypothyroidism reduces circulating levels of adiponectin and leptin, while increasing BChE activity in dogs." | ( Cerón, JJ; Jaillardon, L; Siliart, B; Tvarijonaviciute, A, 2013) |
| "In uterine strips from women treated for hypothyroidism, phasic uterine contractions of larger amplitude (+77%) were observed, with a prolonged duration at 90% relaxation (+138%) and reduced frequency (-55%) compared with values of the control group." | ( Bellabarba, D; Blouin, S; Corriveau, S; Pasquier, JC; Rousseau, É, 2013) |
| "In total, 137 women with treated hypothyroidism and 274 controls were included." | ( Benaglia, L; Busnelli, A; Fedele, L; Leonardi, M; Ragni, G; Somigliana, E, 2013) |
| "Chronic levothyroxin treatment reversed hypothyroidism-induced L-LTP impairment." | ( Alkadhi, KA; Alzoubi, KH, 2014) |
| "Chronic nicotine treatment reversed hypothyroidism-induced impairment of L-LTP at the induction phase." | ( Alkadhi, KA; Alzoubi, KH, 2014) |
| "In patients treated for hypothyroidism, the usual practice is to monitor thyroid-stimulating hormone values yearly once a therapeutic dosage of levothyroxine is determined." | ( Bernard, ME; Garrison, GM; Pecina, J, 2014) |
| "By medical replacement treatment, clinical hypothyroidism (CI) related hypercholesterolemia decreased significantly in 28%." | ( Campanella, N; Catozzo, V; Ferretti, M; Morosini, P; Sampaolo, G; Vichi, G, 2014) |
| "A total of 5689 patients with treated hypothyroidism and 59,937 euthyroid patients were included in the subcohorts." | ( Azoulay, L; Fournier, JP; Yin, H; Yu, OH, 2014) |
| "In such cases, DM may reverse with treatment of hypothyroidism, as was documented in this case." | ( Johnstone, T; Mooney, CT; Terzo, E, 2014) |
| "The decision to treat subclinical hypothyroidism (SCH) with or without autoimmune thyroiditis (AIT) in children, presents a clinical dilemma." | ( Arora, S; Chauhan, VK; Manchanda, RK; Marwaha, RK; Nagpal, L; Narang, A; Sreenivas, V; Verma, SK, 2014) |
| "At present, the drug of choice for the treatment of hypothyroidism is levothyroxine sodium, even though the thyroid gland secretes both thyroxine and 3',3,5-triiodothyronine; the latter is the more active of the two at the cellular level because of its higher affinity for the nuclear thyroid hormone receptors." | ( Botella-Carretero, JI; Escobar-Morreale, HF; Morreale de Escobar, G, 2015) |
| "We studied 15 women with untreated subclinical hypothyroidism (group A), 16 women with treated hypothyroidism (group B) and 17 women with normal thyroid function (group C) who, because of coexistent hypercholesterolemia, were treated with atorvastatin." | ( Gilowski, W; Krysiak, R; Okopien, B, 2015) |
| "Perinatal outcomes of women with treated overt hypothyroidism were similar to women with euthyroidism." | ( Bryant, SN; Casey, BM; Cunningham, FG; McIntire, DD; Nelson, DB, 2015) |
| "The identification and treatment of overt hypothyroidism results in pregnancy outcomes similar to women with euthyroidism." | ( Bryant, SN; Casey, BM; Cunningham, FG; McIntire, DD; Nelson, DB, 2015) |
| "Many patients treated for primary hypothyroidism have an unexplained reduced quality of life (QOL)." | ( Berghout, A; Kelderman-Bolk, N; Tijssen, JP; Visser, TJ, 2015) |
| "They were treated for hypothyroidism but their growth did not improve as expected." | ( Hojat, L; Schweiger, M, 2016) |
| "Inadequately treated maternal hypothyroidism is associated with numerous adverse fetal and maternal outcomes." | ( Foeller, ME; Silver, RM, 2015) |
| "Several side-effects in mRCC treatment, such as hypothyroidism, can be used as positive prognostic factors and indicate good response to therapy." | ( Golčić, M; Petković, M, 2016) |
| "In total, 611 patients with treated hypothyroidism, aged 60-80 years (72% females, mean age 71 ± 6 years) were included in the study." | ( Akirov, A; Gimbel, H; Grossman, A; Shimon, I; Shochat, T, 2017) |
| "The prevalence of treated hypothyroidism, untreated subclinical hypothyroidism, and untreated clinical hypothyroidism was 4." | ( Bordiú, E; Calle-Pascual, A; Castaño, L; Castell, C; Chacón, MR; Chaves, FJ; Delgado, E; Franch, J; Garcia-Fuentes, E; Gaztambide, S; Girbés, J; Goday, A; Gutierrez-Repiso, C; Lago-Sampedro, A; Lillo, JA; Lopez-Alba, A; Maldonado-Araque, C; Menendez, E; Ocon-Sanchez, P; Ortega, E; Peláez, L; Perez-Valero, V; Rojo-Martínez, G; Soriguer, F; Urrutia, I; Valdés, S; Vendrell, J, 2017) |
| "L-thyroxine (LT4) treatment of hypothyroidism, particularly in patients with thyroid- stimulating hormone (TSH) >10mU/L, results in improved lipid profile, as LT4 stimulates low-density lipoprotein cholesterol (LDL-C) degradation and the conversion of cholesterol in bile acids by inducing LDL-receptor and 7 alpha hydroxylase expression, respectively." | ( Brenta, G; Duntas, LH, 2016) |
| "The use of levothyroxine to treat subclinical hypothyroidism is controversial." | ( Aubert, CE; Aujesky, D; Bauer, DC; Baumgartner, C; Blum, MR; Browne, JP; Byrne, S; Collet, TH; Dekkers, OM; den Elzen, WPJ; Du Puy, RS; Ellis, G; Feller, M; Floriani, C; Ford, I; Gussekloo, J; Hendry, K; Hurley, C; Jukema, JW; Kean, S; Kearney, PM; Kelly, M; Krebs, D; Langhorne, P; McCarthy, G; McCarthy, V; McConnachie, A; McDade, M; Messow, M; Mooijaart, SP; O'Flynn, A; O'Riordan, D; Poortvliet, RKE; Quinn, TJ; Rodondi, N; Russell, A; Sattar, N; Sinnott, C; Smit, JWA; Stott, DJ; Van Dorland, HA; Walsh, EK; Walsh, KA; Watt, T; Westendorp, RGJ; Wilson, R, 2017) |
| "A subset of patients being treated for hypothyroidism do not feel well while taking levothyroxine (LT4) replacement therapy, despite having a normal serum thyroid stimulating hormone level." | ( Jonklaas, J, 2017) |
| "The strategy of non-adherence treatment in hypothyroidism is well defined with oral testing of L-thyroxine, followed by oral or parenteral weekly administration of the drug." | ( Grino, M; Moatti Vacher-Coponat, P; Morange, I; Oliver, C; Retornaz, F, 2017) |
| "Until recently, treatment of hypothyroidism has been accomplished using monotherapy of synthetic L-thyroxine (L-T4) sodium tablets that should be taken 30-60 minutes before breakfast." | ( Cipri, C; Frasoldati, A; Graziano, F; Grimaldi, F; Guastamacchia, E; Guglielmi, R; Misischi, I; Negro, R; Papini, E; Triggiani, V, 2018) |
| "However, treatment of hypothyroidism and hyperthyroidism corrected cardiac irisin levels (Fig." | ( Atici, E; Baltaci, AK; Menevse, E; Mogulkoc, R, 2018) |
| "Compliance to levothyroxine treatment in hypothyroidism is compromised by daily and fasting schedule." | ( de Carvalho, GA; Graf, H; Mesa Junior, C; Paz-Filho, G, 2018) |
| "Levothyroxine replacement treatment in hypothyroidism is unable to restore physiological thyroxine and triiodothyronine concentrations in serum and tissues completely." | ( Beukhof, CM; Brigante, G; Chaker, L; Dorssers, LCJ; Franssen, GJ; Gillis, AJM; Kam, BLR; Looijenga, LHJ; Massolt, ET; Peeters, RP; van Ginhoven, TM; Visser, TJ; Visser, WE, 2018) |
| "Patients with untreated hypothyroidism have consistently reported symptoms of severe cognitive impairments." | ( Blum, D; Chaalal, A; Enderlin, V; Laroche, S; Poirier, R, 2019) |
| "Compounds to treat hypothyroidism in the absence of cardiac side effects are urgently required." | ( Li, P; Liu, S; Xing, R; Yang, H; Yu, H, 2019) |
| "We studied patients with untreated subclinical hypothyroidism (n = 53, 65 ± 12 years old) compared with euthyroid subjects (n = 55, 64 ± 10 years old)." | ( Goda, A; Koide, K; Koshiba, M; Masaki, M; Masuyama, T; Miyazaki, A, 2019) |
| "Prompt recognition and treatment of hypothyroidism is, therefore, of utmost importance to optimize physical and neurodevelopmental outcomes." | ( Leung, AAC; Leung, AKC, 2019) |
| "In the treatment for hypothyroidism, a historically symptom-orientated approach has given way to reliance on a single biochemical parameter, thyroid stimulating hormone (TSH)." | ( Dietrich, JW; Hoermann, R; Larisch, R; Midgley, JEM; Toft, AD, 2019) |
| "In patients with newly treated hypothyroidism, cardiovascular event rates were similar for generic and brand L-T4." | ( Bernet, V; Kusumoto, F; Mwangi, R; Sangaralingham, LR; Smallridge, RC; Van Houten, H, 2019) |
| "Optimal treatment of hypothyroidism requires a partnership between patient and physician." | ( Duntas, LH; Jonklaas, J, 2019) |
| "A 41-year-old Caucasian man under treatment for hypothyroidism presented with acute-onset severe pain in his forearm for no obvious reason and was admitted to our emergency room." | ( Aarsæther, E; Due, J; Halvorsen, H; Joakimsen, R; Sildnes, T; Sivertsen, O, 2020) |
| "Standard treatment for hypothyroidism does not restore the normal metabolic reaction to carbohydrate which is observed in healthy people." | ( Assis, GG; Kozacz, A; Sanocka, U; Ziemba, AW, 2021) |
| "Left untreated, hypothyroidism may contribute to other chronic health conditions." | ( Abdelhamid, E; Adel, A; Al Ali, N; Al Juhani, NR; Al Mourad, M; Alamri, FA; Alhazmi, AS; Almaghamsy, AM; Alsefri, S; Alzahrani, AS; Alzahrani, MDA; El Bahtimy, H; Hafez, K; Hussein, WI; Ismail, M; Saeedi, MY, 2020) |
| "The standard treatment for hypothyroidism of any etiology remains monotherapy with levothyroxine, which allows to restore the euthyroid state in most patients." | ( Martirosian, NS; Petunina, NA; Trukhina, LV, 2019) |
| "Levothyroxine treatment for hypothyroidism in early pregnancy has inconsistent outcomes." | ( Li, X; Wang, C; Xu, H; Zhou, Q, 2020) |
| "Thyroid hormone monitoring and treatment of hypothyroidism is necessary in all patients who have undergone surgical excision of the thyroid gland." | ( Castro-Revoredo, I; Kaplan, JL, 2020) |
| "Delayed treatment of hypothyroidism can lead to profound neurodevelopmental delay." | ( Boyle, MA; Breen, CM; Salama, MF, 2021) |
| "The standard treatment of hypothyroidism is levothyroxine (LT4), which is available as tablets or soft-gel capsules in Denmark." | ( Attanasio, R; Bonnema, SJ; Frølich, JS; Hegedüs, L; Nagy, EV; Negro, R; Papini, E; Perros, P; Riis, KR, 2021) |
| "Levothyroxine (L-T4) treatment of overt hypothyroidism can be more challenging in elderly compared to young patients." | ( Effraimidis, G; Feldt-Rasmussen, U; Watt, T, 2021) |
| "THESIS (Treatment of Hypothyroidism in Europe by Specialists: an International Survey) is a large-scale survey of European physicians who treat patients with hypothyroidism." | ( Attanasio, R; Bednarczuk, T; Hegedüs, L; Nagy, EV; Negro, R; Papini, E; Perros, P; Ruchała, M, 2021) |
| "In the background of untreated hypothyroidism, a possible association of ovarian hyperstimulation syndrome (OHSS) and reactive pituitary hyperplasia should be kept in mind, thus preventing unnecessary interventions." | ( Abraham, MS; Jagannathan, P; Narayanan, R; Sampathkumar, G, 2022) |
| "Brain fog in patients treated for hypothyroidism was associated most frequently with fatigue and cognitive symptoms." | ( Batista, SP; Batistuzzo, A; Bianco, AC; Ettleson, MD; Jonklaas, J; Laiteerapong, N; McAninch, E; Raine, A; Ribeiro, MO; Teixeira, MCTV, 2022) |
| "The standard treatment of hypothyroidism is levothyroxine (LT-4)." | ( Attanasio, R; Hegedüs, L; Lantz, M; Nagy, EV; Papini, E; Perros, P; Planck, T, 2021) |
| "The standard treatment for hypothyroidism is levothyroxine (LT4), which in the Republic of Belarus is available in tablet form whereas liothyronine (LT3) is not registered, but patients can purchase them on their own abroad." | ( Attanasio, R; Dydyshka, YV; Hegedüs, L; Lоbashova, VL; Nagy, E; Negro, R; Papini, E; Perros, P; Shepelkevich, AP; Yurenya, EV, 2021) |
| "Célkitűzés: A THESIS (Treatment of Hypothyroidism in Europe by Specialists: an International Survey) célja, hogy felmérjük az európai és közte jelen munkánkban a magyar endokrinológusok hypothyreosiskezelési szokásait és az LT4 esetleges alkalmazását pajzsmirigy-működészavarral nem járó állapotokban." | ( Attanasio, R; Berta, E; Bodor, M; Hegedűs, L; Lengyel, IM; Nagy, VE; Negro, R; Papini, E; Perros, P, 2022) |
| "Célkitűzés: A THESIS (Treatment of Hypothyroidism in Europe by Specialists: an International Survey) célja, hogy felmérjük az európai és közte jelen munkánkban a magyar endokrinológusok hypothyreosiskezelési szokásait és az LT4 esetleges alkalmazását pajzsmirigy-működészavarral nem járó állapotokban." | ( Attanasio, R; Berta, E; Bodor, M; Hegedűs, L; Lengyel, IM; Nagy, VE; Negro, R; Papini, E; Perros, P, 2022) |
| "THESIS (Treatment of Hypothyroidism in Europe by Specialists: an International Survey) had been conducted to assess treatment preferences among European endocrinologists." | ( Attanasio, R; Berta, E; Bodor, M; Hegedűs, L; Lengyel, IM; Nagy, VE; Negro, R; Papini, E; Perros, P, 2022) |
| "The main indication for levothyroxine treatment is hypothyroidism of any type." | ( Krátký, J, 2022) |
| "Most women with pre-existing treated hypothyroidism require an increase in levothyroxine (LT4) dosing to maintain euthyroidism during gestation." | ( Pearce, EN, 2022) |
| "Compared to euthyroidism, untreated subclinical hypothyroidism was associated with a higher risk of cardiovascular events or death if Thyroid Stimulating Hormone was above 10mIU/L at baseline." | ( Agrawal, U; Azcoaga-Lorenzo, A; Bauer, BS; Fagbamigbe, AF; McCowan, C, 2022) |
| "Levothyroxine (LT4) is a convenient treatment for hypothyroidism." | ( Huang, SM; Lai, YW, 2022) |
| "During future treatment of hypothyroidism, close attention to liver function may also be required to prevent a possible increased risk of HCC." | ( Li, L; Lu, L; Sun, M; Wan, B, 2022) |
| "From a health care quality perspective, treatment of hypothyroidism should be evaluated not just on its effectiveness for the individual patients but also to the extent to which patients of different sociodemographic groups are treated equally." | ( Ettleson, MD; Papaleontiou, M, 2022) |
| "Levothyroxine is commonly used to treat hypothyroidism." | ( Britz, S; Diel, P; Hanke, L; Poeten, P; Spanke, L, 2023) |
| "Levothyroxine is commonly used to treat hypothyroidism." | ( Britz, S; Diel, P; Hanke, L; Poeten, P; Spanke, L, 2023) |
| "Using a methimazole-treated hypothyroidism rat model, we investigated cerebellar autophagy, growth factor, and apoptotic mechanisms that participate in motor functions." | ( Bandyopadhyay, S; Garg, A; Gupta, K; Kashyap, A; Malik, R; Mishra, J; Shukla, M; Singh, D; Vishwakarma, J, 2023) |
| "For the treatment of hypothyroidism, patients are usually placed on lifelong levothyroxine replacement therapy." | ( Baloch, AA; Fatima, N; Kiran, Z; Shaikh, KS; Tariq, N, 2023) |
| "The standard of care for treatment of hypothyroidism remains levothyroxine (LT4) at doses to achieve biochemical and clinical euthyroidism." | ( Biondi, B; Celi, FS; McAninch, EA, 2023) |
| "Persistent symptoms in patients treated for hypothyroidism are common." | ( Ahluwalia, R; Baldeweg, SE; Boelaert, K; Chatterjee, K; Dayan, C; Okosieme, O; Pearce, SH; Priestley, J; Taylor, P; Vaidya, B; Zammitt, N, 2023) |
| "The main treatment for hypothyroidism is thyroid hormone replacement using levothyroxine to normalize serum thyroid hormone levels." | ( Abdel Rahman, AM; Alfadda, AA; Almalki, RH; Benabdelkamel, H; Dahabiyeh, LA; Jaber, MA; Masood, A; Musambil, M, 2023) |
| "After treatment of hypothyroidism, the thyroid panel, EF, and pericardial effusion improved significantly." | ( Ashfaq, S; Kilaru, V; Velez-Oquendo, G; Ye, K, 2023) |
| "In conclusion, in patients with untreated primary hypothyroidism, levothyroxine replacement therapy based on HOMA-IR and QUICKI did not improve insulin resistance; however, lipid profile was significantly improved following levothyroxine administration." | ( Gohari-Lasaki, S; Manzari, T; Mobasseri, M; Najafipour, F; Ostadrahimi, A; Sadra, V; Tutunchi, H, 2023) |
| "This is of importance as untreated hypothyroidism leads to fatigue, decreased physical activity, suboptimal height gain, disordered puberty and poor neurocognitive development in children with long term detrimental outcomes." | ( Chan, D; Farhad Vasanwala, R; Kan, SY; Pravin, RR; Soh, SY, 2023) |