Page last updated: 2024-08-05 11:53:27

dihydroxy-5beta-cholanic acid

A hydroxy-5beta-cholanic acid carrying two hydroxy groups at unspecified positions.

ChEBI ID: 23775

Members (5)

MemberDefinitionRole
chenodeoxycholic acidA dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively.chenodeoxycholic acid
deoxycholic acidA bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively.deoxycholic acid
isoursodeoxycholic acidA dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by beta-hydroxy groups at positions 3 and 7.isoursodeoxycholic acid
obeticholic acidA dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.obeticholic acid
ursodeoxycholic acidA bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones.ursodeoxycholic acid

Research

Studies (10,863)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,728 (34.32)18.7374
1990's1,836 (16.90)18.2507
2000's1,892 (17.42)29.6817
2010's2,507 (23.08)24.3611
2020's900 (8.29)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,053 (7.80%)5.53%
Reviews1,444 (10.69%)6.00%
Case Studies769 (5.69%)4.05%
Observational43 (0.32%)0.25%
Other10,196 (75.50%)84.16%