Page last updated: 2024-08-05 11:38:36

organooxygen heterocyclic antibiotic

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ChEBI ID: 25807

Members (5)

MemberDefinitionRole
adefovirA dimeric naphthopyran with formula C32H26O10, originally isolated from Aspergillus niger.aurasperone A
cycloserineA 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis).D-cycloserine zwitterion; D-cycloserine
fumagillinA meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.fumagillin
nanaomycin aA pyranonaphthoquinone antibiotic from strain OS-3966 of Streptomyces rosa var. notoensis.nanaomycin A
nitrofurantoinAn imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA.nitrofurantoin

Research

Studies (5,386)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,177 (58.99)18.7374
1990's435 (8.08)18.2507
2000's619 (11.49)29.6817
2010's883 (16.39)24.3611
2020's272 (5.05)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials359 (6.15%)5.53%
Reviews375 (6.43%)6.00%
Case Studies375 (6.43%)4.05%
Observational8 (0.14%)0.25%
Other4,716 (80.85%)84.16%