Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 17.2168 | 1 | 3 |
15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
67.9K protein | Vaccinia virus | Potency | 11.2698 | 2 | 3 |
activating transcription factor 6 | Homo sapiens (human) | Potency | 57.1125 | 1 | 1 |
aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 13.9473 | 2 | 3 |
alpha-galactosidase | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
AR protein | Homo sapiens (human) | Potency | 30.9091 | 5 | 5 |
aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 35.9458 | 2 | 2 |
Ataxin-2 | Homo sapiens (human) | Potency | 56.5948 | 1 | 1 |
ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.7569 | 1 | 1 |
ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 57.7018 | 2 | 2 |
Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 5.6608 | 2 | 2 |
Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 21.0494 | 1 | 4 |
Chain A, HADH2 protein | Homo sapiens (human) | Potency | 21.1490 | 2 | 4 |
Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 22.4394 | 3 | 6 |
Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 17.7407 | 1 | 2 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
Chain B, HADH2 protein | Homo sapiens (human) | Potency | 21.1490 | 2 | 4 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 0.0474 | 1 | 1 |
cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 2 | 2 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 35.7089 | 1 | 1 |
DNA polymerase beta | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 32.1220 | 1 | 2 |
DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 13.6190 | 1 | 3 |
endonuclease IV | Escherichia coli | Potency | 44.6684 | 1 | 1 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 31.1213 | 4 | 4 |
estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 23.2677 | 3 | 3 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 26.0915 | 9 | 9 |
euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 3.6675 | 1 | 3 |
farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 50.9016 | 1 | 1 |
flap endonuclease 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 1 |
geminin | Homo sapiens (human) | Potency | 2.4291 | 3 | 3 |
GLI family zinc finger 3 | Homo sapiens (human) | Potency | 30.8038 | 3 | 3 |
Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
heat shock protein beta-1 | Homo sapiens (human) | Potency | 52.1267 | 2 | 2 |
Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 1.2589 | 1 | 2 |
histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 95.5763 | 2 | 2 |
histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
Integrin alpha-IIb | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
Integrin beta-3 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
lamin isoform A-delta10 | Homo sapiens (human) | Potency | 5.2884 | 2 | 3 |
lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.5893 | 1 | 1 |
lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
Microtubule-associated protein tau | Homo sapiens (human) | Potency | 19.6222 | 2 | 2 |
mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 24.7028 | 2 | 2 |
muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0178 | 1 | 1 |
nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 6.3096 | 1 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 3.0453 | 2 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 0.2060 | 1 | 1 |
nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 23.3507 | 2 | 2 |
nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 63.9218 | 2 | 2 |
Parkin | Homo sapiens (human) | Potency | 1.8356 | 1 | 1 |
peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 0.2133 | 1 | 1 |
peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 20.8647 | 3 | 3 |
phosphopantetheinyl transferase | Bacillus subtilis | Potency | 19.9526 | 1 | 1 |
polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
pregnane X nuclear receptor | Homo sapiens (human) | Potency | 25.2800 | 1 | 1 |
RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 60.0476 | 2 | 2 |
retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 65.4951 | 3 | 3 |
retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 53.9177 | 1 | 1 |
Smad3 | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 0.1122 | 1 | 1 |
TDP1 protein | Homo sapiens (human) | Potency | 1.7074 | 2 | 5 |
thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 22.9833 | 1 | 2 |
thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 40.0145 | 2 | 2 |
v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 44.0972 | 2 | 2 |
vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 42.8000 | 1 | 2 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
ATP-citrate synthase | Rattus norvegicus (Norway rat) | Ki | 11.6667 | 3 | 3 |
Dihydroorotate dehydrogenase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 10.0000 | 1 | 1 |
Dihydroorotate dehydrogenase (fumarate) | Saccharomyces cerevisiae S288C | IC50 | 10.0000 | 1 | 1 |
G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 39.0000 | 1 | 1 |
G-protein coupled receptor 35 | Homo sapiens (human) | Ki | 137.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 98.0400 | 4 | 5 |
Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 5.4000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
Mitogen-activated protein kinase 12 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
Mitogen-activated protein kinase 13 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
Vesicular glutamate transporter 3 | Rattus norvegicus (Norway rat) | Ki | 1,300.0000 | 1 | 1 |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |