A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1.
| Member | Definition | Class |
|---|
| (+)-epicatechin | A catechin that is flavan carrying five hydroxy substituents at positions 3, 3', 4', 5 and 7 (the 2S,3S-stereoisomer). | (+)-epicatechin |
| acetaminophen | A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. | paracetamol |
| ahr 5850 | An organic sodium salt having amfenac(1-) as the counterion. | sodium (2-amino-3-benzoylphenyl)acetate |
| amfenac | An oxo monocarboxylic acid that is benzophenone in which one of the phenyl groups is substituted by an amino group and a carboxymethyl group at position 2 and 3, respectively. The corresponding carboxamide, nepafenac, is a prodrug of amfenac and is used for the treatment of pain and inflammation following cataract surgery. | amfenac |
| aspirin | A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity. | acetylsalicylic acid |
| centaureidin | A trihydroxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii and Athroisma proteiforme. | centaureidin |
| dexketoprofen | A monocarboxylic acid that is (S)-hydratropic acid substituted at position 3 on the phenyl ring by a benzoyl group. A cyclooxygenase inhibitor, it is used to relieve short-term pain, such as muscular pain, dental pain and dysmenorrhoea. | dexketoprofen |
| droxicam | An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. | droxicam |
| eupomatenoid 6 | A member of the class of benzofurans that is 1-benzofuran substituted by a 4-hydroxyphenyl group at position 2, a methyl group at position 3 and a prop-1-en-1-yl group at position 5. It is a lignan derivative isolated from the roots of Krameria lappacea. | rataniaphenol II |
| fenoprofen | A monocarboxylic acid that is propanoic acid in which one of the hydrogens at position 2 is substituted by a 3-phenoxyphenyl group. A non-steroidal anti-inflammatory drug, the dihydrate form of the calcium salt is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding. | fenoprofen |
| fenoprofen calcium | The dihydrate form of the calcium salt of fenoprofen. A non-steroidal anti-inflammatory drug, it is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding. | fenoprofen calcium |
| ibuprofen | A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group. | ibuprofen |
| ketorolac | A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure. | 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; ketorolac |
| ketorolac tromethamine | An organoammonium salt resulting from the mixture of equimolar amounts of ketorolac and tromethamine (tris). It has potent non-sedating analgesic and moderate anti-inflammatory effects. It is used in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. | ketorolac tromethamine |
| myricetin | A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants. | myricetin |
| naproxen | A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes. | naproxen |
| naproxen sodium | An organic sodium salt consisting of equimolar amounts of naproxen(1-) anions and sodium anions. | naproxen sodium |
| nepafenac | A monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted into the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery. | nepafenac |
| nitroflurbiprofen | A carboxylic ester obtained by formal condensation of the carboxy group of flurbiprofen with the free hydroxy group of 4-(nitrooxy)butanol. It is a non-steroidal anti-inflammatory agent showing inhibitory effects against the cyclooxygenases COX1 and COX2. | nitroflurbiprofen |
| piroxicam | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxide with the exocyclic nitrogen of 2-aminopyridine. A non-steroidal anti-inflammatory drug of the oxicam class, it is used to relieve pain and works by preventing the production of endogenous prostaglandins involved in the mediation of pain, stiffness, tenderness and swelling. | piroxicam |
| sc 560 | A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-methoxyphenyl, trifluoromethyl and 4-chlorophenyl groups, respectively. Unlike many members of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors, SC-560 is selective for COX-1. | SC560 |
| valerylsalicylate | A valerate ester that is salicylic acid in which the phenolic hydrogen is replaced by a valeryl (pentanoyl) group. | valerylsalicylic acid |
| yakuchinone-a | A ketone that is heptan-3-one substituted by a 4-hydroxy-3-methoxyphenyl group at position 1 and a phenyl group at position 7. Isolated from in Alpinia oxyphylla, it exhibits antineoplastic and inhibitory activities against COX-1, COX-2 and NO synthase. | 1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 21.5432 | 1 | 6 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 6.6403 | 1 | 4 |
| 67.9K protein | Vaccinia virus | Potency | 8.7440 | 2 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 21.4210 | 1 | 6 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.8048 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.8913 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 26.1789 | 7 | 15 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 30.3832 | 2 | 6 |
| arylsulfatase A | Homo sapiens (human) | Potency | 8.1600 | 1 | 4 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 25.4435 | 2 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 13.9480 | 1 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 11.0265 | 4 | 5 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 23.9341 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 9.5344 | 2 | 13 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 42.9133 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 55.8129 | 1 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 21.4655 | 1 | 9 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 6.2067 | 2 | 7 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 57.7315 | 1 | 2 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 20.5990 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 30.0437 | 2 | 3 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 8.7419 | 2 | 7 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 19.5147 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 1.6370 | 3 | 11 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 14.4774 | 1 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 4.3622 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 8.7419 | 2 | 7 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 59.0465 | 2 | 7 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 9.6373 | 1 | 5 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 18.2140 | 1 | 8 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 20.6124 | 1 | 4 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 14.6450 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 22.5358 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 16.4346 | 2 | 12 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 22.7342 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 69.2179 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 16.4816 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 12.9890 | 1 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 0.1995 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 6.5121 | 2 | 4 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 15.0030 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 19.4003 | 2 | 7 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 6.7990 | 2 | 12 |
| endonuclease IV | Escherichia coli | Potency | 25.1189 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 22.2441 | 5 | 24 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 30.5252 | 5 | 7 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 9.3532 | 1 | 13 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 19.7317 | 4 | 19 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 6.0072 | 3 | 8 |
| G | Vesicular stomatitis virus | Potency | 20.6124 | 1 | 4 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 16.4346 | 1 | 6 |
| geminin | Homo sapiens (human) | Potency | 1.4703 | 2 | 6 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 5.3080 | 2 | 2 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 4.5640 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 21.6600 | 2 | 8 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 21.7615 | 1 | 3 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 33.4139 | 2 | 3 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 7.0795 | 1 | 1 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 14.8721 | 2 | 30 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 6.3030 | 2 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 20.6124 | 1 | 4 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 40.5229 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 3.5036 | 2 | 4 |
| IDH1 | Homo sapiens (human) | Potency | 14.7644 | 1 | 4 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 20.6124 | 1 | 8 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 0.3982 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 21.7792 | 2 | 5 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 1.1855 | 1 | 3 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 11.2392 | 1 | 5 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 0.2984 | 2 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 24.9979 | 4 | 9 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 23.6602 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 21.1784 | 2 | 9 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.2018 | 2 | 4 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 21.6765 | 1 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.1170 | 2 | 4 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 11.0455 | 1 | 3 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 10.3225 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 60.5718 | 2 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 44.0420 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 14.7722 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 21.7914 | 2 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 23.3512 | 3 | 10 |
| Parkin | Homo sapiens (human) | Potency | 8.2539 | 2 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 45.0390 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 0.0128 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 30.5866 | 3 | 8 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 10.8951 | 1 | 1 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 2.0585 | 3 | 3 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 9.9827 | 1 | 4 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 1.5044 | 1 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 16.4321 | 1 | 3 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 21.8886 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 15.3553 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 1.9953 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.6768 | 2 | 9 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 3.6626 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 7.0252 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 20.7990 | 3 | 8 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 16.0393 | 1 | 2 |
| RGS12 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 19.8812 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 9.4662 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 38.1274 | 1 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 38.1274 | 1 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 9.6985 | 1 | 2 |
| snurportin-1 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 37.6460 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 19.5754 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 24.2344 | 2 | 13 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 3.5481 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 22.6284 | 4 | 16 |
| Thrombopoietin | Homo sapiens (human) | Potency | 7.5060 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 43.7908 | 2 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 9.0731 | 2 | 9 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 11.0448 | 2 | 4 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 29.5338 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 5.0740 | 1 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 46.5811 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 1.5000 | 1 | 1 |
| 2-5A-dependent ribonuclease | Homo sapiens (human) | IC50 | 264.0000 | 1 | 1 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 14.0000 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 1.7500 | 1 | 4 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 235.1100 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 37.8000 | 1 | 1 |
| Acid-sensing ion channel 1 | Rattus norvegicus (Norway rat) | IC50 | 288.0192 | 5 | 9 |
| Acid-sensing ion channel 3 | Rattus norvegicus (Norway rat) | IC50 | 512.8610 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 2,348.3333 | 1 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 2,348.3333 | 1 | 3 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 24.8000 | 1 | 1 |
| Albumin | Bos taurus (cattle) | IC50 | 3.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Ki | 187,444,500,000.0000 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C2 | Homo sapiens (human) | IC50 | 16.2800 | 2 | 2 |
| Aldo-keto reductase family 1 member C21 | Mus musculus (house mouse) | IC50 | 12.3000 | 1 | 1 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 8.9520 | 4 | 5 |
| Aldo-keto reductase family 1 member C4 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 33.2000 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 30.2000 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 6.7600 | 2 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 9.9143 | 7 | 7 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | IC50 | 44.0000 | 1 | 1 |
| Arginase | Leishmania amazonensis | IC50 | 2.1000 | 1 | 1 |
| Arginase | Leishmania amazonensis | Ki | 1.2000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 5 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 3.9800 | 1 | 1 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2.0000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 14.4950 | 3 | 4 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 399.4714 | 4 | 14 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 645.4500 | 1 | 2 |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | IC50 | 0.0500 | 1 | 1 |
| C-X-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 0.0500 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 114.5000 | 2 | 6 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 622.0000 | 3 | 5 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 592.2188 | 5 | 16 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 147.6615 | 2 | 13 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 149.6769 | 2 | 13 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 148.1615 | 2 | 13 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 9.2300 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 312.0000 | 3 | 5 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 349.6313 | 5 | 16 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 147.8923 | 2 | 13 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | IC50 | 100.0000 | 2 | 4 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 148.2231 | 2 | 13 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 209.0385 | 2 | 13 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 170.1154 | 2 | 13 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 197.9615 | 2 | 13 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 148.0462 | 2 | 13 |
| Carbonic anhydrase 9 | Homo sapiens (human) | IC50 | 100.0000 | 2 | 2 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 146.9214 | 3 | 14 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 0.9400 | 3 | 3 |
| Caspase-1 | Homo sapiens (human) | IC50 | 18.8673 | 1 | 15 |
| Caspase-3 | Homo sapiens (human) | IC50 | 18.8673 | 1 | 15 |
| Caspase-4 | Homo sapiens (human) | IC50 | 18.8673 | 1 | 15 |
| Caspase-5 | Homo sapiens (human) | IC50 | 18.8673 | 1 | 15 |
| Caspase-9 | Homo sapiens (human) | IC50 | 18.8673 | 1 | 15 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 10.2000 | 1 | 1 |
| Cell division control protein 42 homolog | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Chain A, Pancreatic alpha-amylase | Homo sapiens (human) | Ki | 110.0000 | 1 | 2 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 1 | 4 |
| Cholinesterase | Homo sapiens (human) | IC50 | 600.0000 | 1 | 1 |
| Cystathionine beta-synthase | Homo sapiens (human) | IC50 | 18.8000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.3700 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0270 | 2 | 2 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 4 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 50.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 4 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 505.0000 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 23.0000 | 1 | 1 |
| Dehydrogenase/reductase SDR family member 9 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 3,780.0000 | 1 | 2 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 30.7664 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3A isoform a | Homo sapiens (human) | IC50 | 17.5000 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 2.3900 | 1 | 1 |
| DNA primase TraC | Escherichia coli | IC50 | 700.0000 | 1 | 1 |
| DNA-(apurinic or apyrimidinic site) endonuclease | Homo sapiens (human) | IC50 | 0.3200 | 2 | 2 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.4000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 2 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | Ki | 136.4500 | 1 | 2 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 792.3667 | 2 | 6 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 100.6667 | 2 | 3 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 2.1200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.3500 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 11.6500 | 2 | 2 |
| Genome polyprotein | Zika virus | Ki | 0.8000 | 1 | 1 |
| Glutathione hydrolase 1 proenzyme | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 13.5000 | 1 | 1 |
| Hormone-sensitive lipase | Rattus norvegicus (Norway rat) | IC50 | 1.2000 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 3.1750 | 4 | 4 |
| integrase, partial | Human immunodeficiency virus 1 | IC50 | 0.9489 | 2 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 52.5000 | 2 | 2 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 2.9200 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 12.5000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 1.5000 | 3 | 3 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 388.6667 | 3 | 3 |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | IC50 | 0.9489 | 2 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 2.1000 | 2 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 1.9400 | 1 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 157.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 2.9000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 7.8500 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 106.9400 | 1 | 5 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Myoglobin | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Ki | 1.7000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 84.0333 | 3 | 6 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0005 | 1 | 1 |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | IC50 | 34.9850 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 3.2600 | 2 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 210.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 57.7500 | 3 | 4 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 28.3800 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 82.9250 | 33 | 49 |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | IC50 | 0.2200 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 720.4696 | 68 | 102 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | Ki | 62.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | Ki | 9.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 754.5237 | 9 | 19 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 17.1433 | 4 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 298.1724 | 63 | 90 |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | IC50 | 0.5400 | 2 | 2 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 376.7971 | 27 | 38 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 52.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | Ki | 9.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | IC50 | 347.9889 | 5 | 9 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 17.1433 | 4 | 6 |
| Prostaglandin-H2 D-isomerase | Mus musculus (house mouse) | IC50 | 500.1333 | 2 | 3 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 11.0000 | 2 | 2 |
| Protein E6 | Human papillomavirus 16 | IC50 | 0.8500 | 1 | 1 |
| Ras-related C3 botulinum toxin substrate 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 1.6900 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 0.3100 | 1 | 2 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 6,700.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 1.3750 | 1 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 1.5620 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 36.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.7800 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 150.0000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 2 | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Rattus norvegicus (Norway rat) | Ki | 33.5000 | 1 | 1 |
| Solute carrier family 22 member 11 | Homo sapiens (human) | Ki | 107.8000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 51.3878 | 1 | 4 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 11.4333 | 1 | 3 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Ki | 19.8000 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 347.0521 | 1 | 4 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 516.9000 | 1 | 5 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 791.6267 | 2 | 3 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 126.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A4 | Rattus norvegicus (Norway rat) | Ki | 2,430.0000 | 1 | 1 |
| steroidogenic factor 1 | Homo sapiens (human) | IC50 | 67.5250 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 91.3000 | 1 | 2 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 46.5250 | 2 | 4 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 100.5000 | 1 | 1 |
| Tubulin alpha-1A chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin alpha-1B chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin alpha-1C chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin alpha-3C chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin alpha-3E chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin alpha-4A chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-1 chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-2A chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-2B chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-3 chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-4A chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-4B chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-6 chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tubulin beta-8 chain | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 6.4000 | 1 | 1 |
| Tyrosine-protein kinase transforming protein Fps | Fujinami sarcoma virus | Ki | 1.8000 | 1 | 1 |
| Urotensin-2 receptor | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 1 | 2 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 2.3800 | 1 | 1 |