A hormone agonist that binds to and activates progesterone receptors.
ChEBI ID: 70709
| Member | Definition | Class |
|---|---|---|
| dienogest | A steroid hormone that is 17beta-hydroxy-3-oxoestra-4,9-diene substituted at position 17 by a cyanomethyl group. Used as an oral contraceptive. | dienogest |
| promegestone | A progestin consisting of 17beta-propionylestra-4,9-dien-3-one substituted at position 17 by a methyl group. | promegestone |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 450 (40.69) | 18.7374 |
| 1990's | 202 (18.26) | 18.2507 |
| 2000's | 170 (15.37) | 29.6817 |
| 2010's | 209 (18.90) | 24.3611 |
| 2020's | 75 (6.78) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 134 (11.75%) | 5.53% |
| Reviews | 71 (6.23%) | 6.00% |
| Case Studies | 29 (2.54%) | 4.05% |
| Observational | 11 (0.96%) | 0.25% |
| Other | 895 (78.51%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 1.3183 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 0.0002 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Progesterone receptor | Homo sapiens (human) | Kd | 0.0004 | 1 | 1 |