Page last updated: 2024-09-28

Thyroglossal Cyst

A cyst in the neck caused by persistence of portions of, or by lack of closure of, the primitive thyroglossal duct. (Dorland, 27th ed)

Synonyms(3)

Synonym
Thyrolingual Cyst
Thyroglossal Cyst
Thyroglossal Duct Cyst

Research Excerpts

Overview

ExcerptReference
"Thyroglossal duct cyst is a common congenital cyst in the neck."( Moreno, AJ; Wang, B, 2019)

Treatment

ExcerptReference
"Plunging ranula, lymphangioma, thyroglossal duct cyst, thyroid cyst, auricular hematoma, and salivary mucocele showed better responses to OK-432 therapy than did branchial cleft cyst."( Aoyagi, M; Fukase, S; Ishida, A; Ohta, N; Suzuki, Y, 2010)
"Five patients with recurrent thyroglossal duct cyst after surgery received this therapy between January 2014 and February 2020 on an outpatient basis, without hospitalization."( Fukase, S; Nakazumi, M; Ohta, N; Sato, T; Suzuki, T, 2021)

Research

Studies (65)

TimeframeStudies, This Condition (%)All Conditions %
pre-199014 (21.54)23.3326
1990's7 (10.77)12.5806
2000's12 (18.46)18.1394
2010's26 (40.00)28.8240
2020's6 (9.23)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low10
iodine0low70
nitrous oxide0low10
uric acid0low10
apnea0low50
ondansetron0low10
thyroxine0low80
triiodothyronine0low20
technetium0low30
silver nitrate0low10
iopamidol0low10
fluorodeoxyglucose f180low40
cobalt0low10
inositol 3-phosphate0low20
picibanil0low90
phenylephrine hydrochloride0low10
barium0low10
phosphorus0low10
cefotaxime0low10
sodium pertechnetate tc 99m0low60
triiodothyronine, reverse0low10
tetracycline0low10

Protein Targets (467)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
thioredoxin reductase4004
ATAD5 protein, partial2002
TDP1 protein5005
Microtubule-associated protein tau2002
estrogen-related nuclear receptor alpha7007
arylsulfatase A1001
euchromatic histone-lysine N-methyltransferase 24004
Bloom syndrome protein isoform 13003
D(1A) dopamine receptor1001
lamin isoform A-delta105005
neuropeptide S receptor isoform A3003
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0101
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0101
Solute carrier family 22 member 60202
Albumin0112
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Solute carrier family 22 member 60203
Solute carrier family 22 member 70102
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80304
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0001
Solute carrier family 22 member 110102
Solute carrier family 22 member 80101
Beta-lactamase VIM-1 0001
Solute carrier family 22 member 70102
Protein-arginine deiminase type-40202
Luciferase2002
acetylcholinesterase3003
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma5005
progesterone receptor3003
retinoic acid nuclear receptor alpha variant 12002
retinoid X nuclear receptor alpha3003
pregnane X nuclear receptor4004
estrogen nuclear receptor alpha7007
peroxisome proliferator activated receptor gamma6006
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
activating transcription factor 62002
v-jun sarcoma virus 17 oncogene homolog (avian)3003
histone deacetylase 9 isoform 32002
nuclear factor erythroid 2-related factor 2 isoform 15005
Voltage-dependent calcium channel gamma-2 subunit2002
Glutamate receptor 22002
USP1 protein, partial3003
AR protein4004
glucocorticoid receptor [Homo sapiens]5005
nuclear receptor subfamily 1, group I, member 21001
peripheral myelin protein 223003
Spike glycoprotein4004
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, 2-oxoglutarate Oxygenase3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Ferritin light chain1001
T cell receptor, partial1001
luteinizing hormone receptor1001
glp-1 receptor, partial3003
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog2002
lens epithelium-derived growth factor p750101
phosphopantetheinyl transferase1001
Caspase 6, apoptosis-related cysteine peptidase0001
SMAD family member 21001
Fumarate hydratase1001
PPM1D protein1001
SMAD family member 31001
GLI family zinc finger 32002
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase1001
Smad31001
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)1001
hypothetical protein, conserved1001
nuclear receptor subfamily 1, group I, member 32002
isocitrate dehydrogenase 1, partial1001
cytochrome P450 family 3 subfamily A polypeptide 44004
farnesoid X nuclear receptor2002
G2002
cytochrome P450 2D62002
polyprotein1001
luciferase1001
bromodomain adjacent to zinc finger domain 2B1001
peroxisome proliferator-activated receptor delta2002
caspase-31001
IDH12002
thyroid stimulating hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
Histone H2A.x2002
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
thyroid hormone receptor beta isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 21001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
caspase-9 isoform alpha precursor0101
thyroid hormone receptor beta isoform 23003
heat shock protein beta-11001
huntingtin isoform 21001
pyruvate kinase PKM isoform a1001
DNA polymerase beta1001
mitogen-activated protein kinase 11001
flap endonuclease 11001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin4004
Vpr2002
survival motor neuron protein isoform d2002
muscleblind-like protein 1 isoform 12002
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Interferon beta2002
HLA class I histocompatibility antigen, B alpha chain 2002
Albumin0001
Cellular tumor antigen p534004
Amyloid-beta precursor protein0101
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1B adrenergic receptor0303
Amine oxidase [flavin-containing] A0101
Alpha-1D adrenergic receptor0303
Sodium-dependent noradrenaline transporter 0011
Cruzipain0101
Alpha-synuclein1102
Alpha-1A adrenergic receptor0303
Guanine nucleotide-binding protein G1001
Inositol monophosphatase 11001
TAR DNA-binding protein 431001
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Inositol hexakisphosphate kinase 12002
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Zinc finger protein mex-50011
cytochrome P450 2C9, partial2002
phosphoglycerate kinase1001
ATP-dependent phosphofructokinase1001
5-hydroxytryptamine receptor 3E0113
EWS/FLI fusion protein3003
Gamma-aminobutyric acid receptor subunit pi0213
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
ATP-binding cassette sub-family C member 30202
Multidrug resistance-associated protein 40202
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30101
5-hydroxytryptamine receptor 3B0113
Bile salt export pump0404
Integrin beta-30101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Integrin alpha-IIb0101
Cytochrome P450 3A40101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0101
Neuronal acetylcholine receptor subunit alpha-41102
Beta-2 adrenergic receptor0101
Muscarinic acetylcholine receptor M20101
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2A0101
Gamma-aminobutyric acid receptor subunit beta-10213
Neuronal acetylcholine receptor subunit beta-20202
Beta-1 adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit delta0213
Gamma-aminobutyric acid receptor subunit gamma-20213
D0101
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0101
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit alpha-30213
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Interleukin-6 receptor subunit alpha0101
Alpha-2A adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit gamma-10213
Gamma-aminobutyric acid receptor subunit alpha-20213
5-hydroxytryptamine receptor 3A0101
D(1B) dopamine receptor0101
Beta-3 adrenergic receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
5-hydroxytryptamine receptor 2A0101
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit gamma-30213
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
D(4) dopamine receptor0101
Neuronal acetylcholine receptor subunit beta-40101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
Neuronal acetylcholine receptor subunit alpha-30101
5-hydroxytryptamine receptor 7 0101
Delta-type opioid receptor0101
Mu-type opioid receptor0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 2B0202
Neuronal acetylcholine receptor subunit alpha-40202
5-hydroxytryptamine receptor 3A0214
Neuronal acetylcholine receptor subunit alpha-70101
5-hydroxytryptamine receptor 60001
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit beta-20213
Glutamate receptor ionotropic, NMDA 2C0101
Thyrotropin-releasing hormone receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Neuronal acetylcholine receptor subunit alpha-70101
Potassium voltage-gated channel subfamily H member 20101
Glycine receptor subunit alpha-40101
5-hydroxytryptamine receptor 4 0101
5-hydroxytryptamine receptor 3D0113
Multidrug and toxin extrusion protein 20101
5-hydroxytryptamine receptor 3C0113
GABA theta subunit0213
Canalicular multispecific organic anion transporter 10202
Multidrug and toxin extrusion protein 10101
Gamma-aminobutyric acid receptor subunit epsilon0213
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0213
Histamine H3 receptor0101
Sigma non-opioid intracellular receptor 10101
Leukotriene B4 receptor 10101
Nischarin0101
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
chromobox protein homolog 12002
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit beta-21001
aldehyde dehydrogenase 1 family, member A11001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
histone acetyltransferase KAT2A isoform 11001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
Carbonic anhydrase 120101
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0101
Carbonic anhydrase 10202
Carbonic anhydrase 20202
Polymerase acidic protein0011
Carbonic anhydrase 30101
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0101
Prostaglandin G/H synthase 20101
Carbonic anhydrase 70101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase 90101
Carbonic anhydrase0101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
apical membrane antigen 1, AMA12002
serine/threonine-protein kinase PLK11001
DNA polymerase kappa isoform 11001
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50002
Rap guanine nucleotide exchange factor 31001
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10002
glucocerebrosidase1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Prothrombin0011
Androgen receptor0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Adenosine receptor A10202
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma non-opioid intracellular receptor 10011
Solute carrier organic anion transporter family member 4C10001
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1B30001
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]