Page last updated: 2024-09-28

Dientamoeba fragilis Infection

Gastrointestinal infection with organisms of the genus DIENTAMOEBA.

Synonyms(3)

Synonym
Dientamoeba fragilis Infection
Dientamoeba Infection
Dientamoebiasis

Research

Studies (35)

TimeframeStudies, This Condition (%)All Conditions %
pre-19906 (17.14)23.3326
1990's1 (2.86)12.5806
2000's8 (22.86)18.1394
2010's17 (48.57)28.8240
2020's3 (8.57)9.53
DrugIndicatedRelationship StrengthStudiesTrials
quinacrine0low20
chlorine0low10
iodine0low10
albendazole0low10
chloroquine0low10
ciprofloxacin0low10
clioquinol0low30
furazolidone0low20
iodoquinol0low60
mebendazole0low20
metronidazole0medium224
nalidixic acid0low10
norfloxacin0low10
sulfamethoxazole0low10
tinidazole0low10
trimethoprim0low10
methylprednisolone0low10
emetine0low10
hematoxylin0low10
azomycin0low10
d-alpha tocopherol0low10
diloxanide furoate0low10
hypochlorous acid0low10
ornidazole0medium11
chloroquine diphosphate0low10
secnidazole0medium11
paromomycin0low50
trimethoprim, sulfamethoxazole drug combination0low10
tetracycline0low20
exudates0low10

Protein Targets (504)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase3003
Luciferase5005
glp-1 receptor, partial2002
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma9009
ATAD5 protein, partial5005
Fumarate hydratase4004
TDP1 protein130013
GLI family zinc finger 3110011
AR protein110011
caspase 7, apoptosis-related cysteine protease1001
nuclear receptor subfamily 1, group I, member 37007
progesterone receptor8008
glucocorticoid receptor [Homo sapiens]8008
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha100010
estrogen-related nuclear receptor alpha120012
farnesoid X nuclear receptor6006
pregnane X nuclear receptor110011
estrogen nuclear receptor alpha150015
polyprotein4004
67.9K protein5005
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
caspase-31001
IDH15005
euchromatic histone-lysine N-methyltransferase 2100010
aryl hydrocarbon receptor5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)5005
nuclear receptor subfamily 1, group I, member 25005
Histone H2A.x6006
cellular tumor antigen p53 isoform a4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
chromobox protein homolog 17007
nuclear factor erythroid 2-related factor 2 isoform 25005
transcriptional regulator ERG isoform 31001
thyroid hormone receptor beta isoform 28008
histone deacetylase 9 isoform 33003
heat shock protein beta-13003
mitogen-activated protein kinase 16006
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin120012
Vif0102
peripheral myelin protein 224004
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 16006
DNA dC->dU-editing enzyme APOBEC-3G isoform 11102
lamin isoform A-delta10100010
neuropeptide S receptor isoform A2002
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015015
Voltage-dependent calcium channel gamma-2 subunit6006
Bile salt export pump018018
Interferon beta7007
Cellular tumor antigen p539009
Integrin beta-34004
Integrin alpha-IIb4004
Methionine aminopeptidase0202
Glutamate receptor 26006
Fatty-acid amide hydrolase 10202
Inositol monophosphatase 13003
Canalicular multispecific organic anion transporter 1015015
ATPase family AAA domain-containing protein 55005
Ataxin-27007
EWS/FLI fusion protein7007
Carbonic anhydrase 10102
Carbonic anhydrase 20102
Carbonic anhydrase 40102
Carbonic anhydrase0101
Carbonic anhydrase 150202
thioredoxin reductase5005
PPM1D protein5005
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0202
Spike glycoprotein0123
Replicase polyprotein 1ab0123
glucose-6-phosphate 1-dehydrogenase isoform b0202
flap endonuclease 16006
Transmembrane protease serine 20123
Dihydrofolate reductase 0202
DNA ligase0101
Riboflavin-binding protein0123
Major prion protein0022
Amyloid-beta precursor protein0202
Histidine-rich protein PFHRP-II0203
Procathepsin L0123
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40303
Cytochrome P450 3A40202
Muscarinic acetylcholine receptor M50303
Alpha-2A adrenergic receptor0505
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Spike glycoprotein0202
Replicase polyprotein 1ab0224
Muscarinic acetylcholine receptor M10303
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0303
Alpha-2C adrenergic receptor0505
DNA ligase 10101
Muscarinic acetylcholine receptor M30303
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Spike glycoprotein3126
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20506
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0123
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, 2-oxoglutarate Oxygenase6006
endonuclease IV2002
acetylcholinesterase4004
GALC protein3003
Microtubule-associated protein tau5005
cytochrome P450 family 3 subfamily A polypeptide 49009
cytochrome P450 2D61001
potassium voltage-gated channel subfamily H member 2 isoform d4004
nuclear factor erythroid 2-related factor 2 isoform 16006
Chain A, Cruzipain3003
aldehyde dehydrogenase 1 family, member A1100010
cytochrome P450 2C9 precursor2002
Gamma-aminobutyric acid receptor subunit pi4206
Cytochrome P450 1A20101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
DNA gyrase subunit B0102
DNA gyrase subunit A0305
DNA gyrase subunit B0305
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0203
Cytochrome P450 2D60101
DNA topoisomerase 2-alpha0104
Cytochrome P450 2C9 0303
Gamma-aminobutyric acid receptor subunit beta-14206
Gamma-aminobutyric acid receptor subunit delta4206
Gamma-aminobutyric acid receptor subunit gamma-24206
Gamma-aminobutyric acid receptor subunit alpha-54206
Gamma-aminobutyric acid receptor subunit alpha-34206
DNA gyrase subunit A0102
Gamma-aminobutyric acid receptor subunit gamma-14206
Gamma-aminobutyric acid receptor subunit alpha-24206
Gamma-aminobutyric acid receptor subunit alpha-44206
Gamma-aminobutyric acid receptor subunit gamma-34206
Gamma-aminobutyric acid receptor subunit alpha-64206
Cytochrome P450 2C190101
Multidrug resistance protein MdtK0022
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit alpha-14206
Gamma-aminobutyric acid receptor subunit beta-34206
Gamma-aminobutyric acid receptor subunit beta-24206
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
DNA topoisomerase 4 subunit A0202
DNA topoisomerase 4 subunit B0202
Integrase 0202
GABA theta subunit4206
Gamma-aminobutyric acid receptor subunit epsilon4206
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, JmjC domain-containing histone demethylation protein 3A3003
mu opioid receptor, partial0011
15-lipoxygenase, partial3003
90-kda heat shock protein beta HSP90 beta, partial0202
phosphopantetheinyl transferase3003
SMAD family member 23003
SMAD family member 33003
thioredoxin glutathione reductase3003
Smad31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
estrogen receptor 2 (ER beta)6006
regulator of G-protein signaling 43003
nonstructural protein 15005
bromodomain adjacent to zinc finger domain 2B4004
peroxisome proliferator-activated receptor delta3003
LAP40022
MEP20022
activating transcription factor 66006
polyunsaturated fatty acid lipoxygenase ALOX121001
delta-type opioid receptor0112
kappa-type opioid receptor isoform 10101
vitamin D3 receptor isoform VDRA4004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
huntingtin isoform 24004
nuclear factor NF-kappa-B p105 subunit isoform 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a5005
heat shock protein HSP 90-alpha isoform 20204
DNA polymerase iota isoform a (long)4004
nuclear receptor ROR-gamma isoform 15005
cytochrome P450 3A4 isoform 14004
DNA dC->dU-editing enzyme APOBEC-3F isoform a2002
Histone deacetylase 30101
Carbonic anhydrase 120001
Carbonic anhydrase 30001
Botulinum neurotoxin type A 0101
Alpha-1B adrenergic receptor0314
Catechol O-methyltransferase0202
Carbonic anhydrase 60001
Alpha-1D adrenergic receptor0112
Carbonic anhydrase 5A, mitochondrial0001
Alpha-synuclein1102
Alpha-1A adrenergic receptor0314
Carbonic anhydrase 70001
Nuclear receptor ROR-gamma1001
Histone deacetylase 40101
Disintegrin and metalloproteinase domain-containing protein 173003
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
TAR DNA-binding protein 435005
Histone deacetylase 10101
Carbonic anhydrase 90001
Beta-galactosidase0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Carbonic anhydrase 130001
Histone deacetylase 60101
Histone deacetylase 90101
Carbonic anhydrase 140001
Histone deacetylase 50101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
heat shock protein 90, putative0002
USP1 protein, partial5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 12002
Rap guanine nucleotide exchange factor 32002
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
G4004
alpha-galactosidase1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
replicative DNA helicase0001
recombinase A0011
HLA class I histocompatibility antigen, B alpha chain 4004
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
NS5 0011
Parkin1001
NPC intracellular cholesterol transporter 1 precursor2002
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 12002
Glucose transporter0101
Serine hydrolase RBBP90101
Hexose transporter 1 0101
ATP-dependent translocase ABCB10113
Solute carrier family 2, facilitated glucose transporter member 10101
Hypoxia-inducible factor 1-alpha0102
Dihydroorotate dehydrogenase 0101
Endothelial PAS domain-containing protein 10102
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, RNA-directed RNA polymerase NS50101
WRN1001
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
alkaline phosphatase, intestinal0011
apical membrane antigen 1, AMA12002
hypothetical protein, conserved1001
glucocerebrosidase1001
luciferase1001
pyruvate kinase1001
CDK50001
serine-protein kinase ATM isoform a2002
lysosomal alpha-glucosidase preproprotein1001
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
intestinal alkaline phosphatase precursor0011
DNA polymerase beta1001
serine/threonine-protein kinase PLK12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
DNA polymerase kappa isoform 12002
Tat0101
histone acetyltransferase KAT2A isoform 13003
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Pyruvate kinase PKM0202
Endothelin receptor type B1001
Endothelin-1 receptor1102
phosphoglycerate kinase1001
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
ATP-dependent phosphofructokinase2002
large T antigen0101
citrate synthase 2, partial0011
PAX80001
aryl hydrocarbon receptor nuclear translocator0001
signal transducer and activator of transcription 6, interleukin-4 induced1001
transforming acidic coiled-coil-containing protein 30001
Epidermal growth factor receptor0101
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Adenosine receptor A30202
Mitogen-activated protein kinase 3 0101
Mitogen-activated protein kinase 10101
Mitogen-activated protein kinase 140101
lethal factor (plasmid)2002
Tyrosine-protein kinase ABL10202
Proto-oncogene tyrosine-protein kinase Src0202
Vascular endothelial growth factor receptor 20101
Calmodulin-domain protein kinase 10101
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nuclear receptor subfamily 1 group I member 20011
thyroid stimulating hormone receptor3003
Thioredoxin reductase 0101
thyroid hormone receptor beta isoform a1001
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Lanosterol 14-alpha demethylase0101
interleukin 83003
thyroid stimulating hormone receptor1001
Caspase-71001
caspase-31001
Cytochrome P450 2J20202
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Tyrosyl-DNA phosphodiesterase 10101
N0101
dopamine D1 receptor2002
NPYLR7B0011
arylsulfatase A1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cystic fibrosis transmembrane conductance regulator0101
D(1A) dopamine receptor1001
tumor susceptibility gene 101 protein1001
M-phase phosphoprotein 81001
Glutathione reductase, mitochondrial0101
Major prion protein0101
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
DNA-directed RNA polymerase subunit alpha0101
DNA-directed RNA polymerase subunit omega0101
DNA-directed RNA polymerase subunit beta'0101
DNA-directed RNA polymerase subunit beta0101
Muscarinic acetylcholine receptor M20101
Phospholipase A2, membrane associated0101
Phospholipase A2, membrane associated0101
Acidic phospholipase A2 20101
Acetylcholinesterase0101
Sodium-dependent noradrenaline transporter 0202
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
Trypanothione reductase0202
D(3) dopamine receptor0202
D(1A) dopamine receptor1001
Aldehyde oxidase 10101
Cholinesterase0101
Aldehyde oxidase0101
Cyclic GMP-AMP synthase0101
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
5-hydroxytryptamine receptor 2A0202
Dihydrofolate reductase0304
Protease 0112
Protein-arginine deiminase type-40303
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
Stromelysin-10101
Multidrug transporter MdfA0101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
Solute carrier family 22 member 80001
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
NFKB1 protein, partial1001
Bloom syndrome protein isoform 11001
cytochrome P450 2C19 precursor1001
muscarinic acetylcholine receptor M11001
Solute carrier family 22 member 1 0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Dihydrofolate reductase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2B0101
Metabotropic glutamate receptor 50101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]