Sclerema Neonatorum

A severe, sometimes fatal, disorder of adipose tissue occurring chiefly in preterm or debilitated infants suffering from an underlying illness and manifested by a diffuse, nonpitting induration of the affected tissue. The skin becomes cold, yellowish, mottled, and inflexible.

Synonym
Sclerema Neonatorum

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	25 (83.33)	23.3326
1990's	1 (3.33)	12.5806
2000's	2 (6.67)	18.1394
2010's	1 (3.33)	28.8240
2020's	1 (3.33)	9.53

Drug	Relationship Strength	Studies
ammonium hydroxide	low	1
hydrogen carbonate	low	1
urea	low	1
caffeine	low	1
chlorpromazine	low	1
gentamicin	low	1
apnea	low	1
phenoxybenzamine	low	1
procaine	low	1
aldosterone	low	1
prednisone	low	5
cephalothin	low	1
desoxycorticosterone	low	1
ampicillin	low	1
d-alpha tocopherol	low	3
streptomycin	low	1
cortisone	low	7
pituitrin	low	1
glucagon	low	1
tetracycline	low	1
hyaluronoglucosaminidase	low	1

Protein Targets (529)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
AR protein	9	0	0	9
glucocorticoid receptor [Homo sapiens]	8	0	0	8
thyroid hormone receptor beta isoform a	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
geminin	6	0	0	6
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	1	2	3
Androgen receptor	0	1	0	1
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	1	0	0	1
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	1	0	0	1
Chain A, 2-oxoglutarate Oxygenase	1	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Cruzipain	1	0	0	1
Beta-lactamase	0	0	0	2
acid sphingomyelinase	1	0	0	1
GLS protein	4	0	0	4
GLI family zinc finger 3	7	0	0	7
apical membrane antigen 1, AMA1	1	0	0	1
retinoic acid nuclear receptor alpha variant 1	8	0	0	8
farnesoid X nuclear receptor	3	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
euchromatic histone-lysine N-methyltransferase 2	9	0	0	9
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
chromobox protein homolog 1	6	0	0	6
thyroid hormone receptor beta isoform 2	5	0	0	5
DNA polymerase beta	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
DNA polymerase iota isoform a (long)	3	0	0	3
DNA polymerase kappa isoform 1	4	0	0	4
Carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	3	1	1	5
10 kDa heat shock protein, mitochondrial	0	1	0	1
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	1	0	1
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	2
Beta-lactamase VIM-1	0	0	0	2
ATP-dependent phosphofructokinase	3	0	0	3
thioredoxin reductase	5	0	0	5
ATAD5 protein, partial	2	0	0	2
TDP1 protein	6	0	0	6
Microtubule-associated protein tau	5	0	0	5
estrogen-related nuclear receptor alpha	7	0	0	7
arylsulfatase A	2	0	0	2
Bloom syndrome protein isoform 1	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
lamin isoform A-delta10	4	0	0	4
neuropeptide S receptor isoform A	1	0	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
phosphopantetheinyl transferase	4	0	0	4
RAR-related orphan receptor gamma	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	6	0	0	6
retinoid X nuclear receptor alpha	5	0	0	5
pregnane X nuclear receptor	6	0	0	6
estrogen nuclear receptor alpha	8	0	0	8
thyroid stimulating hormone receptor	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
nuclear receptor ROR-gamma isoform 1	3	0	0	3
muscarinic acetylcholine receptor M1	4	0	0	4
lethal factor (plasmid)	3	0	0	3
ATP-binding cassette sub-family C member 3	0	3	0	3
Multidrug resistance-associated protein 4	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	2	0	0	2
Potassium channel subfamily K member 2	0	1	1	2
Bile salt export pump	0	8	0	8
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Adenosine receptor A3	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Glutamate receptor 2	2	0	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	1	0	1
Adenosine receptor A1	0	2	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	2	1	4
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	1	1	4
Adenosine receptor A2a	0	2	0	4
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Canalicular multispecific organic anion transporter 1	0	3	0	3
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Guanine deaminase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
endonuclease IV	2	0	0	2
WRN	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	4	0	0	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
vitamin D3 receptor isoform VDRA	4	0	0	4
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
heat shock protein beta-1	5	0	0	5
importin subunit beta-1 isoform 1	2	0	0	2
flap endonuclease 1	3	0	0	3
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	2	0	0	2
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	2	0	0	3
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	2	0	0	3
Gamma-aminobutyric acid receptor subunit delta	2	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	2	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	2	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	2	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	2	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	2	0	0	3
Beta-lactamase	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	2	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	2	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	2	0	0	3
Kappa-type opioid receptor	0	0	0	1
Beta-lactamase TEM	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	2	0	0	3
Gamma-aminobutyric acid receptor subunit beta-3	2	0	0	3
Gamma-aminobutyric acid receptor subunit beta-2	2	0	0	3
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
GABA theta subunit	2	0	0	3
Gamma-aminobutyric acid receptor subunit epsilon	2	0	0	3
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 7	0	1	0	2
phosphoglycerate kinase	1	0	0	1
Proteasome subunit beta type-11	0	0	0	1
acetylcholinesterase	1	0	0	1
Fumarate hydratase	1	0	0	1
USP1 protein, partial	4	0	0	4
NFKB1 protein, partial	1	0	0	1
Thrombopoietin	1	0	0	1
Smad3	1	0	0	1
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	2	0	0	2
progesterone receptor	5	0	0	5
NADPH oxidase 1	0	1	0	1
G	2	0	0	2
cytochrome P450 2D6	2	0	0	2
polyprotein	1	0	0	1
67.9K protein	1	0	0	1
peroxisome proliferator-activated receptor delta	5	0	0	5
peroxisome proliferator activated receptor gamma	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	4	0	0	4
Snq2p	0	0	0	1
caspase-3	2	0	0	2
IDH1	2	0	0	2
Adenylate cyclase type 1	0	2	0	2
Histone H2A.x	4	0	0	4
Caspase-7	1	0	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
cytochrome P450 2D6 isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
peripheral myelin protein 22	2	0	0	2
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	2	0	0	2
M-phase phosphoprotein 8	2	0	0	2
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Proteasome subunit alpha type-7	0	0	0	1
Solute carrier family 22 member 1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Transmembrane protease serine 2	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Bile salt export pump	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Epidermal growth factor receptor	0	1	0	1
Interferon beta	3	0	0	3
HLA class I histocompatibility antigen, B alpha chain	2	0	0	2
Albumin	0	0	1	1
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Cellular tumor antigen p53	4	0	0	4
Major prion protein	0	0	1	1
Integrin beta-3	1	0	0	1
Cytochrome P450 1A2	0	0	1	1
Tyrosine-protein kinase Fyn	0	1	0	1
Procathepsin L	0	1	1	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
ATP-dependent translocase ABCB1	0	1	0	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Integrin alpha-IIb	1	0	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Cytochrome P450 2D6	0	1	1	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Cytochrome P450 2C9	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	4	0	4
Sphingomyelin phosphodiesterase	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
D	0	3	0	3
D(3) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	2
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	3
D(4) dopamine receptor	0	2	0	3
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
D(1B) dopamine receptor	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
Histamine H1 receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
D(3) dopamine receptor	0	2	0	3
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	4	0	4
Histamine H2 receptor	1	0	0	1
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	1	0	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Cytochrome P450 2J2	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	3	0	4
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Inositol hexakisphosphate kinase 1	2	0	0	2
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Proteasome subunit beta type-7	0	0	0	1
Ataxin-2	1	0	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Angiotensin-converting enzyme 2	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
cytochrome P450 2C9, partial	2	0	0	2
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
dopamine D1 receptor	1	0	0	1
pregnane X receptor	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
regulator of G-protein signaling 4	1	0	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
peripheral myelin protein 22 isoform 1	1	0	0	1
Glucocorticoid receptor	0	4	1	5
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
TAR DNA-binding protein 43	2	0	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
activating transcription factor 6	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
SMAD family member 2	1	0	0	1
GALC protein	1	0	0	1
SMAD family member 3	1	0	0	1
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
EWS/FLI fusion protein	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
aryl hydrocarbon receptor	1	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
thioredoxin glutathione reductase	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
Nuclear receptor ROR-gamma	1	0	0	1
thyroid stimulating hormone receptor	1	0	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Protein-arginine deiminase type-4	0	3	0	3
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-synuclein	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Research

Studies (30)

Protein Targets (529)

Sclerema Neonatorum

Synonyms(1)

Research Excerpts

Research

Studies (30)

Drugs Studied (31)

Protein Targets (529)