Page last updated: 2024-08-05 12:15:25
sulfamate ester
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ChEBI ID: 48199
Members (4)
Member | Definition | Role |
---|---|---|
acetosulfame | A sulfamate ester that is 1,2,3-oxathiazin-4(3H)-one 2,2-dioxide substituted by a methyl group at position 6. | acesulfame |
bupirimate | A member of the class of aminopyrimidines that is 2-ethylaminopyrimidine carrying methyl, butyl and dimethylaminosulfooxy substituents at posiitons 4, 5 and 6 respectively. | bupirimate |
nucleocidin | A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. | nucleocidin |
topiramate | A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. | topiramate |
Research
Studies (3,219)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 25 (0.78) | 18.7374 |
1990's | 173 (5.37) | 18.2507 |
2000's | 1,352 (42.00) | 29.6817 |
2010's | 1,285 (39.92) | 24.3611 |
2020's | 384 (11.93) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 568 (16.28%) | 5.53% |
Reviews | 605 (17.35%) | 6.00% |
Case Studies | 643 (18.43%) | 4.05% |
Observational | 21 (0.60%) | 0.25% |
Other | 1,651 (47.33%) | 84.16% |