A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives.
| Member | Definition | Role |
|---|
| (Z)-6,6',7,3'a-Diligustilide | | (Z)-6,6',7,3'a-Diligustilide |
| 2,3-dimethylmaleic anhydride | | 2,3-Dimethylmaleic anhydride |
| 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone | | 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone |
| 3-o-ethylascorbic acid | | 3-O-Ethylascorbic acid |
| 4,5-dimethyl-3-hydroxy-2(5h)-furanone | | sotolone |
| 5-hydroxy-4-methoxy-5-(1-methylethenyl)-2-furanone | | 5-hydroxy-4-methoxy-5-(1-methylethenyl)-2-furanone |
| ajugarin i | | Ajugarin I |
| angelica lactone | | beta-angelica lactone |
| ascladiol | A butenolide that is furan-2(5H)-one which is substituted by a hydroxymethyl group at position 4 and a 2-hydroxyethylidene group at position 5 (the 5E isomer). A direct precursor of patulin in cell-free preparations of Penicillium urticae patulin-minus mutants J1 and S11, but not S15. | (E)-ascladiol |
| ascorbic acid 2-sulfate | | L-ascorbic acid 2-sulfate |
| butenolide | | but-2-en-4-olide |
| butyrolactone i | | butyrolactone I |
| firocoxib | An enol ether that is the cyclopropylmethyl ether of 3-hydroxy-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2-one. A selective cyclooxygenase 2 inhibitor, it is used in veterinary medicine for the control of pain and inflammation associated with osteoarthritis in horses and dogs. | firocoxib |
| flupyradifurone | A tertiary amino compound that is ammonia in which the nitrogens have been replaced by (6-chloropyridin-3-yl)methyl, 2,2-difluoroethyl, and 5-oxo-2,5-dihydrofuran-3-yl groups, respectively. A nicotinic acetylcholine receptor (AChR) agonist, it is used as an insecticide to control sucking pests in a variety of crops. | flupyradifurone |
| ligustilide | | (Z)-ligustilide |
| linderalactone | | linderalactone |
| manoalide | A sesterterpenoid isolated from the marine sponge Luffariella variabilis and which has been shown to exhibit inhibitory activity towards phospholipase A2. | manoalide |
| N-butan-2-yl-3,8-dimethyl-2-oxo-1-oxaspiro[4.5]dec-3-ene-4-carboxamide | | N-butan-2-yl-3,8-dimethyl-2-oxo-1-oxaspiro[4.5]dec-3-ene-4-carboxamide |
| protoanemonin | | protoanemonin |
| pulvinic acid | | Pulvinic acid |
| rofecoxib | A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke. | rofecoxib |
| spiromesifen | A butenolide that is but-2-en-4-olide bearing a 2,4,6-trimethylphenyl group at position 3, a 3,3-dimethylbutyryloxy group at position 4 and a spiro-fused cyclopentyl ring at position 5. | spiromesifen |
| trilobacin | A polyketide isolated from the bark of Asimina triloba. It has been shown to exhibit cytotoxicity in the NCI human tumor cell line screen. | trilobacin |
| triptonide | A diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. | triptonide |
| vulpinic acid | | Vulpinic acid |
| wf 3681 | | 3-(4-Hydroxy-5-oxo-3-phenyl-2H-furan-2-yl)propanoic acid |