Compounds > tanikolide
Page last updated: 2024-11-10

tanikolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

tanikolide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5276592
CHEMBL ID479498
SCHEMBL ID9902905
MeSH IDM0350240

Synonyms (7)

Synonym
(6r)-6-(hydroxymethyl)-6-undecyloxan-2-one
tanikolide
CHEMBL479498
SCHEMBL9902905
(+)-tanikolide
248278-40-2
DTXSID401037008

Research Excerpts

Effects

ExcerptReferenceRelevance
"(+)-Tanikolide has been synthesized in eight linear steps with a 31% overall yield. "( Total synthesis of (+)-tanikolide via oxidative lactonization.
Borhan, B; Schomaker, JM, 2004)		1.19
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID376022Antibacterial activity against Bacillus subtilis ATCC 6051 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376016Molluscicidal activity against Biomphalaria glabrata at 10 mg/mL after 24 hrs1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376017Norcotic effect against Carassius auratus at 10 ug/mL after 1 hr1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376019Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376024Toxicity against Carassius auratus1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376023Antibacterial activity against Staphylococcus aureus ATCC 12600 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376020Antibacterial activity against Escherichia coli ATCC 11775 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376015Toxicity against Artemia salina after 24 hrs1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376021Antibacterial activity against Salmonella choleraesuis subsp. choleraesuis ATCC 14028 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376018Antifungal activity against Candida albicans ATCC 14053 at 100 ug/disk by paper disk agar plate method1999Journal of natural products, Sep, Volume: 62, Issue:9
Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's7 (50.00)29.6817
2010's6 (42.86)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
iodine
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.. diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..		7.0310diatomic iodinenutrient
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.		2.0510aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
oxybutynin
oxybutynin: RN given refers to parent cpd. oxybutynin : A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder.		2.0510acetylenic compound;
carboxylic ester;
racemate;
tertiary alcohol;
tertiary amino compound		antispasmodic drug;
calcium channel blocker;
local anaesthetic;
muscarinic antagonist;
muscle relaxant;
parasympatholytic
symclosene
trichloroisocyanuric acid: structure in first source		2.08101,3,5-triazinanes;
organochlorine compound
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		2.1110isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
rhodium
Rhodium: A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh.. rhodium atom : A cobalt group element atom of atomic number 45.		2.0510cobalt group element atom
alkenes
[no description available]		2.0710
malyngolide
malyngolide: from blue-green algea, Lyngbya majuscula; structure given in first source		2.4220aliphatic alcohol
dichlorocarbene
[no description available]		7.0210carbene
cellulose
DEAE-Cellulose: Cellulose derivative used in chromatography, as ion-exchange material, and for various industrial applications.		7.1110glycoside
tetracycline
Tetracycline: A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.. tetracycline : A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria.		210
ConditionIndicatedRelationship StrengthStudiesTrials