Roles > ferroptosis inducer
Page last updated: 2024-08-05 15:06:14

ferroptosis inducer

Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.

ChEBI ID: 173085

Members (18)

MemberDefinitionClass
acetaminophenA member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.paracetamol
ammonium ferric sulfateA compound of ammonium, iron and sulfate in which the ratio of ammonium to iron(2+) to sulfate ions is 2:1:2.ferrous ammonium sulfate (anhydrous)
artesunateAn artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria.artesunate
bay 11-7085A sulfone that is benzene substituted by [(E)-2-cyanoethenyl]sulfonyl and tert-butyl groups at position 1 and 4, respectively. It is an irreversible inhibitor of IkappaB-alpha phosphorylation in cells (IC50 = 10 muM) and prevents the activation of NF-kappaB.BAY11-7085
buthionine sulfoximineA sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.2-amino-4-(S-butylsulfonimidoyl)butanoic acid; S-butyl-DL-homocysteine (S,R)-sulfoximine
buthionine sulfoximineA 2-amino-4-(S-butylsulfonimidoyl)butanoic acid which has S-configuration. It is a inhibitor of gamma-glutamylcysteine synthetase and glutathione (GSH) biosynthesis and is capable of enhancing the apoptotic effects of several chemotherapeutic agents.L-buthionine-(S,R)-sulfoximine
cisplatinA diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups).cisplatin; transplatin
disulfiramAn organic disulfide that results from the formal oxidative dimerisation of N,N-diethyldithiocarbamic acid. A multi-enzyme inhibitor that is used in alcohol aversion therapy and also exhibits anticancer properties.disulfiram
DPI2A thiazolidinone that is 2-sulfanylidene-1,3-thiazolidin-4-one substituted by 3-{[3-(morpholin-4-yl)propyl]amino}-3-oxopropyl and 4-ethylbenzylidene groups at positions 3 and 5, respectively. It is a ferroptosis inducer.DPI2
erastinA member of the class of quinazolines that is quinazolin-4(3H)-one in which the hydrogens at positions 2 and 3 are replaced by 1-{4-[(4-chlorophenoxy)acetyl]piperazin-1-yl}ethyl and 2-ethoxyphenyl groups, respectively. It is an inhibitor of voltage-dependent anion-selective channels (VDAC2 and VDAC3) and a potent ferroptosis inducer.erastin
glutamic acidAn optically active form of glutamic acid having L-configuration.L-glutamic acid
iFSP1A member of the class of pyridobenzimidazoles that is pyrido[1,2-a]benzimidazole substituted by amino, cyano, 4-methylphenyl, and cyano groups at positions 1, 2, 3 and 4, respectively. It is a potent inhibitor of ferroptosis suppressor protein 1 (FSP1) with EC50 of 103 nM. It induces ferroptosis in GPX4 knockout cells that overexpress FSP1.iFSP1
jq1 compoundA member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties.JQ1
lanperisoneA 2-methyl-3-(pyrrolidin-1-yl)-1-[4-(trifluoromethyl)phenyl]propan-1-one in which the methyl group at position 2 adopts R-configuration. It is a muscle relaxant and induces ferroptosis in cancer cells.lanperisone
ML-210An N-acylpiperazine that is piperazine substituted by 5-methyl-4-nitro-1,2-oxazole-3-carbonyl and bis(4-chlorophenyl)methyl groups at positions 1 and 4, respectively. It is a glutathione peroxidase 4 (GPX4) inhibitor which induces ferroptosis in cancer cells expressing the RAS oncogene.ML-210
ML162A monochlorobenzene that is benzene substituted by (chloroacetyl){2-oxo-2-[(2-phenylethyl)amino]-1-(thiophen-2-yl)ethyl}amino, chloro and methoxy groups at positions 1, 3 and 4, respectively. It is a covalent inhibitor of glutathione peroxidase 4 (GPX4) that induces ferroptosis in cells.ML162
simvastatinA member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug.simvastatin
sorafenibA member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 4-chloro-3-trifluorophenyl group while the other is substituted by a phenyl group which, in turn, is substituted at the para position by a [2-(methylcarbamoyl)pyridin-4-yl]oxy group.sorafenib

Research

Studies (80,600)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199010,062 (12.48)18.7374
1990's14,000 (17.37)18.2507
2000's22,387 (27.78)29.6817
2010's25,867 (32.09)24.3611
2020's8,284 (10.28)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials5,944 (7.04%)5.53%
Reviews7,471 (8.85%)6.00%
Case Studies3,398 (4.02%)4.05%
Observational305 (0.36%)0.25%
Other67,329 (79.73%)84.16%

Protein Targets (920)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency6.435618
15-lipoxygenase, partialHomo sapiens (human)Potency0.439214
67.9K proteinVaccinia virusPotency13.483425
acetylcholinesteraseHomo sapiens (human)Potency61.453446
acid sphingomyelinaseHomo sapiens (human)Potency409.723412
activating transcription factor 6Homo sapiens (human)Potency0.627013
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency7.095919
Alpha-synucleinHomo sapiens (human)Potency6.378614
Amyloid-beta precursor proteinHomo sapiens (human)Potency8.976013
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency14.125411
AR proteinHomo sapiens (human)Potency6.0059930
aryl hydrocarbon receptorHomo sapiens (human)Potency45.097634
arylsulfatase AHomo sapiens (human)Potency3.787312
ATAD5 protein, partialHomo sapiens (human)Potency19.6075411
Ataxin-2Homo sapiens (human)Potency27.617226
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency18.093636
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency29.722327
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency7.194412
atrial natriuretic peptide receptor 2 precursorHomo sapiens (human)Potency6.287012
beta-2 adrenergic receptorHomo sapiens (human)Potency10.623822
Bloom syndrome protein isoform 1Homo sapiens (human)Potency9.398126
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency57.457012
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency11.426413
caspase-3Cricetulus griseus (Chinese hamster)Potency10.559012
caspase-3Homo sapiens (human)Potency11.426413
Caspase-7Cricetulus griseus (Chinese hamster)Potency10.559012
Cellular tumor antigen p53Homo sapiens (human)Potency17.003326
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency22.535822
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency21.964013
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency25.118911
Chain A, Beta-lactamaseEscherichia coli K-12Potency41.068025
Chain A, CruzipainTrypanosoma cruziPotency11.669827
Chain A, Ferritin light chainEquus caballus (horse)Potency31.926124
Chain A, HADH2 proteinHomo sapiens (human)Potency13.762626
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency64.193114
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency24.243224
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency18.823112
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency23.838514
Chain B, HADH2 proteinHomo sapiens (human)Potency13.762626
chromobox protein homolog 1Homo sapiens (human)Potency24.163626
core-binding factor subunit beta isoform 2Homo sapiens (human)Potency0.538022
cytochrome P450 2C19 precursorHomo sapiens (human)Potency6.131813
cytochrome P450 2C9 precursorHomo sapiens (human)Potency2.024113
cytochrome P450 2C9, partialHomo sapiens (human)Potency7.391516
cytochrome P450 2D6Homo sapiens (human)Potency15.336013
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency39.810711
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency17.8913212
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency9.835526
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency6.308716
D(1A) dopamine receptorHomo sapiens (human)Potency5.670623
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)Potency8.068712
DNA polymerase eta isoform 1Homo sapiens (human)Potency11.220211
DNA polymerase III, partialBacillus subtilisPotency18.887611
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency54.767816
DNA polymerase kappa isoform 1Homo sapiens (human)Potency63.405412
endonuclease IVEscherichia coliPotency1.412511
estrogen nuclear receptor alphaHomo sapiens (human)Potency14.9350938
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency12.247828
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency6.26751039
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency11.7340112
EWS/FLI fusion proteinHomo sapiens (human)Potency9.0637419
farnesoid X nuclear receptorHomo sapiens (human)Potency2.404527
flap endonuclease 1Homo sapiens (human)Potency62.572126
Fumarate hydrataseHomo sapiens (human)Potency26.838917
GVesicular stomatitis virusPotency7.391516
GABA theta subunitRattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency17.891316
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency17.891316
gemininHomo sapiens (human)Potency13.0354419
GLI family zinc finger 3Homo sapiens (human)Potency7.6879311
glp-1 receptor, partialHomo sapiens (human)Potency7.860823
GLS proteinHomo sapiens (human)Potency20.8837211
glucocerebrosidaseHomo sapiens (human)Potency8.912511
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency17.079736
glucokinase regulatory proteinHomo sapiens (human)Potency31.622811
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency17.024215
Glycoprotein hormones alpha chainHomo sapiens (human)Potency0.501211
GTP-binding nuclear protein Ran isoform 1Homo sapiens (human)Potency31.622811
Guanine nucleotide-binding protein GHomo sapiens (human)Potency50.118711
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1Homo sapiens (human)Potency1.995311
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency2.930922
heat shock protein beta-1Homo sapiens (human)Potency18.2331210
hexokinase-4 isoform 1Homo sapiens (human)Potency31.622811
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency5.2533217
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency19.527714
histone deacetylase 9 isoform 3Homo sapiens (human)Potency11.125511
Histone H2A.xCricetulus griseus (Chinese hamster)Potency6.689627
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency44.964712
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency7.391516
huntingtin isoform 2Homo sapiens (human)Potency5.397212
hypothetical protein, conservedTrypanosoma bruceiPotency8.360826
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency5.691525
IDH1Homo sapiens (human)Potency14.625315
importin subunit beta-1 isoform 1Homo sapiens (human)Potency35.716822
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency7.3915112
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency15.848911
Integrin alpha-IIbHomo sapiens (human)Potency25.118911
Integrin beta-3Homo sapiens (human)Potency25.118911
Interferon betaHomo sapiens (human)Potency9.2865215
lamin isoform A-delta10Homo sapiens (human)Potency9.277929
lethal factor (plasmid)Bacillus anthracis str. A2012Potency3.981111
LuciferasePhotinus pyralis (common eastern firefly)Potency9.677237
lysosomal alpha-glucosidase preproproteinHomo sapiens (human)Potency28.183822
M-phase phosphoprotein 8Homo sapiens (human)Potency8.796014
Microtubule-associated protein tauHomo sapiens (human)Potency11.4799215
mitogen-activated protein kinase 1Homo sapiens (human)Potency25.118911
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency6.365312
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency11.661814
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency28.183811
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)Potency28.183811
neuropeptide S receptor isoform AHomo sapiens (human)Potency19.445415
NFKB1 protein, partialHomo sapiens (human)Potency7.079522
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency3.390513
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency36.984612
Nrf2Homo sapiens (human)Potency7.565122
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency15.4797312
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency23.262612
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency11.334725
Nuclear receptor ROR-gammaHomo sapiens (human)Potency21.131711
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency4.3345215
nuclear receptor subfamily 1, group I, member 2Rattus norvegicus (Norway rat)Potency6.309611
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency10.9786312
Ornithine decarboxylaseRattus norvegicus (Norway rat)Potency25.118911
P53Homo sapiens (human)Potency70.794611
ParkinHomo sapiens (human)Potency26.233223
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency39.550224
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency11.663125
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency47.582614
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency26.3226312
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency5.410826
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency26.854511
phosphopantetheinyl transferaseBacillus subtilisPotency12.528215
PINK1Homo sapiens (human)Potency24.803312
plasminogen precursorMus musculus (house mouse)Potency6.577613
polyproteinZika virusPotency26.838917
polypyrimidine tract-binding protein 1 isoform aHomo sapiens (human)Potency14.550022
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency2.901913
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency8.886114
potassium voltage-gated channel subfamily H member 2 isoform dHomo sapiens (human)Potency19.149812
PPM1D proteinHomo sapiens (human)Potency10.549816
pregnane X nuclear receptorHomo sapiens (human)Potency26.280025
progesterone receptorHomo sapiens (human)Potency4.436925
pyruvate kinaseLeishmania mexicana mexicanaPotency15.848922
pyruvate kinase PKM isoform bHomo sapiens (human)Potency25.118922
RAR-related orphan receptor gammaMus musculus (house mouse)Potency4.1842211
ras-related protein Rab-9AHomo sapiens (human)Potency38.782313
regulator of G-protein signaling 4Homo sapiens (human)Potency19.181817
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency10.4677315
retinoid X nuclear receptor alphaHomo sapiens (human)Potency23.3307314
RGS12Homo sapiens (human)Potency1.995311
runt-related transcription factor 1 isoform AML1bHomo sapiens (human)Potency0.538022
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency0.736033
serine/threonine-protein kinase PLK1Homo sapiens (human)Potency15.389312
SMAD family member 2Homo sapiens (human)Potency15.153022
SMAD family member 3Homo sapiens (human)Potency15.153022
Smad3Homo sapiens (human)Potency7.5768410
snurportin-1Homo sapiens (human)Potency35.716822
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency5.470525
survival motor neuron protein isoform dHomo sapiens (human)Potency28.362713
TAR DNA-binding protein 43Homo sapiens (human)Potency9.053212
TDP1 proteinHomo sapiens (human)Potency8.0677225
thioredoxin glutathione reductaseSchistosoma mansoniPotency10.000011
thioredoxin reductaseRattus norvegicus (Norway rat)Potency8.4405314
ThrombopoietinHomo sapiens (human)Potency6.493724
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency18.8277312
thyroid stimulating hormone receptorHomo sapiens (human)Potency36.3762411
thyrotropin-releasing hormone receptorHomo sapiens (human)Potency23.526723
transient receptor potential cation channel subfamily V member 1Homo sapiens (human)Potency11.220211
tyrosine-protein kinase YesHomo sapiens (human)Potency30.951612
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency6.577613
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency6.577613
USP1 protein, partialHomo sapiens (human)Potency26.111614
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency5.307627
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency17.4373513
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency22.757018
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency17.024215
VprHuman immunodeficiency virus 1Potency12.589311

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)IC504.290522
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)IC500.784388
3-hydroxy-3-methylglutaryl-coenzyme A reductaseSchizosaccharomyces pombe 972h-IC5095.200011
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHomo sapiens (human)Ki34.001322
3-hydroxy-3-methylglutaryl-coenzyme A reductase Rattus norvegicus (Norway rat)IC500.011222
5-hydroxytryptamine receptor 1AHomo sapiens (human)Ki1.181011
5-hydroxytryptamine receptor 2AHomo sapiens (human)Ki1.959011
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC5034.547011
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki11.020022
5-hydroxytryptamine receptor 2CHomo sapiens (human)Ki0.417011
5-hydroxytryptamine receptor 5AHomo sapiens (human)Ki3.296011
5-hydroxytryptamine receptor 6Homo sapiens (human)IC5016.001011
5-hydroxytryptamine receptor 6Homo sapiens (human)Ki6.821022
5-hydroxytryptamine receptor 7Homo sapiens (human)Ki7.071011
Adenosine receptor A3Homo sapiens (human)IC500.356011
Adenosine receptor A3Homo sapiens (human)Ki0.201011
Aldehyde dehydrogenase, mitochondrialHomo sapiens (human)IC503.400011
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC5070.370011
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)Ki69.812011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)IC500.356011
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)Ki0.201011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC500.356011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)Ki0.201011
Alpha-2A adrenergic receptorHomo sapiens (human)IC504.904011
Alpha-2A adrenergic receptorHomo sapiens (human)Ki1.839011
Alpha-2B adrenergic receptorHomo sapiens (human)IC503.218011
Alpha-2B adrenergic receptorHomo sapiens (human)Ki1.469011
Alpha-ketoglutarate-dependent dioxygenase FTOHomo sapiens (human)IC501,000.000011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC5013.734011
Angiopoietin-1 receptorHomo sapiens (human)IC500.003255
Angiotensin-converting enzyme 2 Homo sapiens (human)IC509.350011
apelin receptorHomo sapiens (human)IC502.630011
Arachidonate 5-lipoxygenase-activating proteinHomo sapiens (human)IC5044.000011
AromataseHomo sapiens (human)IC500.126917
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000014
ATP-citrate synthase Rattus norvegicus (Norway rat)Ki300.000011
ATP-dependent translocase ABCB1Homo sapiens (human)IC5029.580055
Aurora kinase AHomo sapiens (human)IC503.800044
Bifunctional aspartokinase/homoserine dehydrogenase 1Escherichia coli K-12Ki38,000.000012
Bifunctional epoxide hydrolase 2Homo sapiens (human)IC500.012011
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferaseMycobacterium tuberculosis H37RvIC5085.030011
Bile salt export pumpHomo sapiens (human)IC50189.5786514
Bile salt export pumpRattus norvegicus (Norway rat)IC501,000.000011
Breakpoint cluster region proteinHomo sapiens (human)GI507.300011
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)IC503.100011
Bromodomain testis-specific proteinHomo sapiens (human)IC500.19021313
Bromodomain-containing protein 1Homo sapiens (human)IC5044.500011
Bromodomain-containing protein 2Homo sapiens (human)IC500.09592222
Bromodomain-containing protein 2Homo sapiens (human)Ki0.012844
Bromodomain-containing protein 3Homo sapiens (human)IC500.05731818
Bromodomain-containing protein 3Homo sapiens (human)Ki0.007844
Bromodomain-containing protein 4Homo sapiens (human)IC500.8257119119
Bromodomain-containing protein 4Homo sapiens (human)Ki0.019388
C-C chemokine receptor type 2Homo sapiens (human)IC503.322512
C-C chemokine receptor type 2Homo sapiens (human)Ki1.284012
C-C chemokine receptor type 4Homo sapiens (human)IC508.395011
C-C chemokine receptor type 4Homo sapiens (human)Ki4.397011
C-C chemokine receptor type 5Homo sapiens (human)IC5023.661011
C-C chemokine receptor type 5Homo sapiens (human)Ki18.284011
C-X-C chemokine receptor type 2Homo sapiens (human)IC506.013011
C-X-C chemokine receptor type 2Homo sapiens (human)Ki4.209011
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC50111.400025
Carbamate kinaseGiardia intestinalisIC500.600011
Carbonic anhydrase 1Homo sapiens (human)Ki122.2188516
Carbonic anhydrase 12Homo sapiens (human)Ki147.6615213
Carbonic anhydrase 13Mus musculus (house mouse)Ki149.6769213
Carbonic anhydrase 14Homo sapiens (human)Ki148.1615213
Carbonic anhydrase 15Mus musculus (house mouse)Ki9.230011
Carbonic anhydrase 2Homo sapiens (human)Ki121.5062516
Carbonic anhydrase 3Homo sapiens (human)Ki147.8923213
Carbonic anhydrase 4Homo sapiens (human)Ki148.2231213
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki209.0385213
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Ki170.1154213
Carbonic anhydrase 6Homo sapiens (human)Ki197.9615213
Carbonic anhydrase 7Homo sapiens (human)Ki138.0526314
Carbonic anhydrase 9Homo sapiens (human)Ki137.7933415
Casein kinase I isoform alphaHomo sapiens (human)IC500.250011
Caspase-1Homo sapiens (human)IC501.800011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]Escherichia coliKi15.000011
Chain A, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)IC500.821012
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2Homo sapiens (human)Ki0.000515
Chain B, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)IC500.821011
CREB-binding proteinHomo sapiens (human)IC509.715333
Cyclin-CHomo sapiens (human)IC500.066222
Cyclin-dependent kinase 19Homo sapiens (human)IC500.206011
Cyclin-dependent kinase 2Homo sapiens (human)IC50150.000011
Cyclin-dependent kinase 4Homo sapiens (human)IC503.000022
Cyclin-dependent kinase 6Homo sapiens (human)IC500.130011
Cyclin-dependent kinase 8Homo sapiens (human)IC502.01651010
Cystine/glutamate transporterHomo sapiens (human)IC500.180033
Cytochrome P450 1A2Homo sapiens (human)IC502.410022
Cytochrome P450 2C9 Homo sapiens (human)IC5050.000011
Cytochrome P450 2D6Homo sapiens (human)IC5010.000011
Cytochrome P450 2J2Homo sapiens (human)IC5050.000011
Cytochrome P450 3A4Homo sapiens (human)IC505.026444
D(1A) dopamine receptorHomo sapiens (human)IC503.285012
D(1A) dopamine receptorHomo sapiens (human)Ki1.642512
D(2) dopamine receptorHomo sapiens (human)IC5023.018011
D(2) dopamine receptorHomo sapiens (human)Ki7.673011
D(3) dopamine receptorHomo sapiens (human)IC502.272012
D(3) dopamine receptorHomo sapiens (human)Ki0.771512
D(4) dopamine receptorHomo sapiens (human)IC503.150011
D(4) dopamine receptorHomo sapiens (human)Ki1.105011
Discoidin domain-containing receptor 2Homo sapiens (human)IC500.021522
DNA-dependent protein kinase catalytic subunitHomo sapiens (human)IC5050.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)IC503.300011
Ephrin type-B receptor 4Homo sapiens (human)IC500.544267
Epidermal growth factor receptorHomo sapiens (human)IC506.437788
Excitatory amino acid transporter 1Homo sapiens (human)IC5076.450346
Excitatory amino acid transporter 1Homo sapiens (human)Ki33.311412
Excitatory amino acid transporter 2Homo sapiens (human)IC5065.978424
Excitatory amino acid transporter 2Homo sapiens (human)Ki62.547812
Excitatory amino acid transporter 3Homo sapiens (human)IC5041.119524
Excitatory amino acid transporter 3Homo sapiens (human)Ki25.084812
Excitatory amino acid transporter 4Rattus norvegicus (Norway rat)IC5012.693024
fatty acid synthaseHomo sapiens (human)IC5010.400022
Fatty-acid amide hydrolase 1Homo sapiens (human)IC50363.078011
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)IC506.100011
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)Ki0.390011
Fibroblast growth factor receptor 1Homo sapiens (human)IC500.2827612
Fructose-1,6-bisphosphatase 1Homo sapiens (human)IC50101.23801010
G1/S-specific cyclin-D1Homo sapiens (human)IC503.000011
Gasdermin-DHomo sapiens (human)IC500.400011
Gasdermin-DMus musculus (house mouse)IC500.400011
glucose-6-phosphate 1-dehydrogenase isoform bHomo sapiens (human)IC5080.000011
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium bergheiIC5056.700033
Glutamate carboxypeptidase 2Homo sapiens (human)IC50428.000022
Glutamate receptor 1Homo sapiens (human)IC500.613011
Glutamate receptor 1Rattus norvegicus (Norway rat)IC500.588544
Glutamate receptor 1Homo sapiens (human)Ki1.360733
Glutamate receptor 1Rattus norvegicus (Norway rat)Ki0.634522
Glutamate receptor 2Homo sapiens (human)IC500.613011
Glutamate receptor 2Rattus norvegicus (Norway rat)IC500.588544
Glutamate receptor 2Homo sapiens (human)Ki0.940033
Glutamate receptor 2Rattus norvegicus (Norway rat)Ki0.445245
Glutamate receptor 3Homo sapiens (human)IC500.613011
Glutamate receptor 3Rattus norvegicus (Norway rat)IC500.588544
Glutamate receptor 3Rattus norvegicus (Norway rat)Ki2.312244
Glutamate receptor 4Homo sapiens (human)IC500.613011
Glutamate receptor 4Rattus norvegicus (Norway rat)IC500.588544
Glutamate receptor 4Homo sapiens (human)Ki0.868033
Glutamate receptor 4Rattus norvegicus (Norway rat)Ki0.727022
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)IC500.380035
Glutamate receptor ionotropic, kainate 1Homo sapiens (human)Ki0.701022
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)Ki0.128457
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)IC500.380035
Glutamate receptor ionotropic, kainate 2Homo sapiens (human)Ki1.106022
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)Ki0.956679
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)IC500.380035
Glutamate receptor ionotropic, kainate 3Homo sapiens (human)Ki0.789022
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)Ki0.420146
Glutamate receptor ionotropic, kainate 4Rattus norvegicus (Norway rat)IC500.380035
Glutamate receptor ionotropic, kainate 4Rattus norvegicus (Norway rat)Ki0.063011
Glutamate receptor ionotropic, kainate 5Rattus norvegicus (Norway rat)IC500.380035
Glutamate receptor ionotropic, kainate 5Homo sapiens (human)Ki0.733733
Glutamate receptor ionotropic, kainate 5Rattus norvegicus (Norway rat)Ki0.063011
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)Ki8.495056
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)IC500.070022
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)IC500.153244
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)Ki8.495056
Glutathione reductase, mitochondrialHomo sapiens (human)IC5053.700011
Glutathione reductase, mitochondrialHomo sapiens (human)Ki42.700011
Glycogen synthase kinase-3 betaHomo sapiens (human)IC5012.487534
Hepatocyte growth factor receptorHomo sapiens (human)IC505.750011
Histone acetyltransferase p300Homo sapiens (human)IC5019.400011
Histone deacetylase 1Homo sapiens (human)IC500.291011
Histone deacetylase 11 Homo sapiens (human)IC500.291011
Histone deacetylase 2Homo sapiens (human)IC500.291011
Histone deacetylase 3Homo sapiens (human)IC500.291011
Histone deacetylase 4Homo sapiens (human)IC500.291011
Histone deacetylase 5Homo sapiens (human)IC500.291011
Histone deacetylase 6Homo sapiens (human)IC500.291011
Histone deacetylase 7Homo sapiens (human)IC500.291011
Histone deacetylase 8Homo sapiens (human)IC500.291011
Histone deacetylase 9Homo sapiens (human)IC500.291011
Histone-lysine N-methyltransferase EHMT1Homo sapiens (human)IC501.600011
Histone-lysine N-methyltransferase EHMT2Homo sapiens (human)IC500.600011
Homeodomain-interacting protein kinase 1Homo sapiens (human)IC500.100011
Homeodomain-interacting protein kinase 2Homo sapiens (human)IC500.100011
Homeodomain-interacting protein kinase 3Homo sapiens (human)IC500.100011
Homeodomain-interacting protein kinase 4Homo sapiens (human)IC500.051522
Insulin receptorHomo sapiens (human)IC505.300011
Insulin receptor Rattus norvegicus (Norway rat)IC500.003411
Kappa-type opioid receptorHomo sapiens (human)IC506.103011
Kappa-type opioid receptorHomo sapiens (human)Ki2.441011
large T antigenBetapolyomavirus macacaeIC5010.730011
Lysine-specific demethylase 5AHomo sapiens (human)IC5010.000011
Lysyl oxidase homolog 2Homo sapiens (human)IC500.150011
Lysyl oxidase homolog 3Homo sapiens (human)IC500.093011
Lysyl oxidase homolog 4Homo sapiens (human)IC500.059011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)IC500.038522
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC500.262011
Mast/stem cell growth factor receptor KitHomo sapiens (human)IC500.1937915
melanocortin receptor 4Homo sapiens (human)IC5066.261733
Metabotropic glutamate receptor 1Homo sapiens (human)Ki3.606733
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)Ki0.340011
Metabotropic glutamate receptor 2Homo sapiens (human)Ki7.650044
Metabotropic glutamate receptor 3Homo sapiens (human)Ki9.000011
Metabotropic glutamate receptor 4Homo sapiens (human)Ki5.600044
Metabotropic glutamate receptor 4Rattus norvegicus (Norway rat)Ki3.400022
Metabotropic glutamate receptor 5Homo sapiens (human)Ki4.316733
Metabotropic glutamate receptor 6Homo sapiens (human)Ki38.000011
Metabotropic glutamate receptor 7Homo sapiens (human)Ki5,400.000011
Metabotropic glutamate receptor 8Homo sapiens (human)IC500.005711
Metabotropic glutamate receptor 8Homo sapiens (human)Ki9.500011
Metabotropic glutamate receptor 8Rattus norvegicus (Norway rat)Ki3.400022
Mitogen-activated protein kinase 1Homo sapiens (human)IC500.109511
Mitogen-activated protein kinase 14Homo sapiens (human)IC500.622888
Mitogen-activated protein kinase 3 Homo sapiens (human)IC500.764022
Monoglyceride lipaseHomo sapiens (human)IC500.809522
Mu-type opioid receptorHomo sapiens (human)IC503.511011
Mu-type opioid receptorHomo sapiens (human)Ki1.425011
Multidrug resistance-associated protein 4Homo sapiens (human)IC50133.000014
MyoglobinHomo sapiens (human)IC502.300011
NACHT, LRR and PYD domains-containing protein 3 Mus musculus (house mouse)IC503.000011
nucleotide-binding oligomerization domain-containing protein 2 isoform 1Homo sapiens (human)IC506.225011
perilipin-1Homo sapiens (human)IC506.959011
perilipin-5Homo sapiens (human)IC501.622011
Phosphatidylinositol 3-kinase catalytic subunit type 3Homo sapiens (human)IC500.021522
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)IC5050.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)IC5050.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)IC5050.000012
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)IC5050.000011
photoreceptor-specific nuclear receptorHomo sapiens (human)IC501.164011
Platelet-derived growth factor receptor alphaHomo sapiens (human)IC500.427011
Platelet-derived growth factor receptor betaHomo sapiens (human)IC500.116499
Platelet-derived growth factor receptor betaMus musculus (house mouse)IC500.123528
Polyamine deacetylase HDAC10Homo sapiens (human)IC500.291011
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)IC5022.223012
Procathepsin LHomo sapiens (human)IC509.350011
Prolyl 4-hydroxylaseParamecium bursaria Chlorella virus 1IC501,000.000011
Prostaglandin G/H synthase 1Homo sapiens (human)IC50200.000011
Prostaglandin G/H synthase 1Ovis aries (sheep)IC50372.000011
Prostaglandin G/H synthase 2Homo sapiens (human)IC500.003411
Protein-lysine 6-oxidaseHomo sapiens (human)IC500.320011
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)GI500.101333
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)IC500.026088
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)IC500.390011
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)IC500.13332932
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)Ki0.006011
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)IC500.131011
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)IC501.500022
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)IC503.600011
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)IC5014.520011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)GI503.133033
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)IC500.03482121
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirusIC509.350011
Replicase polyprotein 1abBetacoronavirus England 1IC5015.383323
Replicase polyprotein 1abHuman coronavirus 229EIC509.350011
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC506.3094910
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusIC509.350022
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2Ki3.710011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusKi3.710011
Retinal dehydrogenase 1Homo sapiens (human)IC500.130011
RuvB-like 1Homo sapiens (human)IC5066.000011
RuvB-like 2Homo sapiens (human)IC5066.000011
Serine/threonine-protein kinase A-RafHomo sapiens (human)IC500.008733
Serine/threonine-protein kinase B-rafHomo sapiens (human)GI501.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC500.36995862
Serine/threonine-protein kinase B-rafHomo sapiens (human)Ki0.032733
Serine/threonine-protein kinase B-raf Mus musculus (house mouse)IC500.130011
Serine/threonine-protein kinase mTORHomo sapiens (human)IC5050.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)Ki17.560014
Serine/threonine-protein kinase PLK2Homo sapiens (human)Ki17.560014
Serine/threonine-protein kinase PLK3Homo sapiens (human)Ki17.560014
Serine/threonine-protein kinase PLK4Homo sapiens (human)Ki17.560014
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)IC500.175022
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)IC500.049011
Sodium-dependent dopamine transporter Homo sapiens (human)IC504.637011
Sodium-dependent dopamine transporter Homo sapiens (human)Ki3.684011
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC5070.370011
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki69.812011
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)IC500.001111
Solute carrier family 22 member 6Rattus norvegicus (Norway rat)Ki2,099.000011
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)IC507.775044
Spike glycoproteinBetacoronavirus England 1IC509.350011
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusIC509.350011
transactivating tegument protein VP16 [Human herpesvirus 1]Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC504.426011
Transmembrane protease serine 2Homo sapiens (human)IC509.350011
tumor necrosis factorHomo sapiens (human)IC506.058511
type-1 angiotensin II receptorHomo sapiens (human)IC506.637011
Tyrosine-protein kinase ABL1Homo sapiens (human)GI507.300011
Tyrosine-protein kinase ABL1Homo sapiens (human)IC500.100022
Tyrosine-protein kinase ABL1Mus musculus (house mouse)IC500.225911
Tyrosine-protein kinase HCKHomo sapiens (human)IC500.530012
Tyrosine-protein kinase LckHomo sapiens (human)IC500.060011
Tyrosine-protein kinase MerHomo sapiens (human)IC501.370011
Vascular endothelial growth factor receptor 1 Homo sapiens (human)IC500.060044
Vascular endothelial growth factor receptor 2Danio rerio (zebrafish)IC502.600011
Vascular endothelial growth factor receptor 2Homo sapiens (human)IC500.10007985
Vascular endothelial growth factor receptor 2Mus musculus (house mouse)IC500.112928
Vascular endothelial growth factor receptor 2Homo sapiens (human)Ki0.007433
Vascular endothelial growth factor receptor 3Homo sapiens (human)IC500.019155
Vascular endothelial growth factor receptor 3Mus musculus (house mouse)IC500.126917

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000011
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)Kd10.000033
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd15.000044
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)Kd10.000033
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd30.000011
AarF domain-containing protein kinase 1Homo sapiens (human)Kd30.000011
Actin-related protein 2Homo sapiens (human)Kd30.000011
Actin-related protein 3Homo sapiens (human)Kd30.000011
Activated CDC42 kinase 1Homo sapiens (human)Kd16.666733
Activin receptor type-1Homo sapiens (human)Kd15.000044
Activin receptor type-1BHomo sapiens (human)Kd15.000044
Activin receptor type-2AHomo sapiens (human)Kd10.000033
Activin receptor type-2BHomo sapiens (human)Kd15.000044
Acyl-CoA dehydrogenase family member 10Homo sapiens (human)Kd30.000011
Acyl-CoA dehydrogenase family member 11Homo sapiens (human)Kd30.000011
Adenine phosphoribosyltransferaseHomo sapiens (human)Kd30.000011
Adenosine kinaseHomo sapiens (human)Kd30.000011
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000012
ADP/ATP translocase 2Homo sapiens (human)Kd30.000011
ADP/ATP translocase 3Homo sapiens (human)Kd30.000011
ALK tyrosine kinase receptorHomo sapiens (human)Kd10.000033
Angiopoietin-1 receptorHomo sapiens (human)Kd2.325044
Ankyrin repeat and protein kinase domain-containing protein 1Homo sapiens (human)Kd10.000033
AP2-associated protein kinase 1Homo sapiens (human)Kd15.000044
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DHX30Homo sapiens (human)Kd30.000011
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd15.000044
Atypical kinase COQ8B, mitochondrialHomo sapiens (human)Kd10.000033
Aurora kinase AHomo sapiens (human)Kd15.000044
Aurora kinase BHomo sapiens (human)Kd7.830044
Aurora kinase CHomo sapiens (human)Kd0.210033
bcl-2-like protein 11 isoform 1Homo sapiens (human)EC5070.600011
BDNF/NT-3 growth factors receptorHomo sapiens (human)Kd2.100033
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000011
BMP-2-inducible protein kinaseHomo sapiens (human)Kd15.000044
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd18.000045
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd16.666733
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd15.000044
Breakpoint cluster region proteinHomo sapiens (human)Kd30.000011
Bromodomain testis-specific proteinHomo sapiens (human)Kd0.178677
Bromodomain-containing protein 2Homo sapiens (human)Kd0.08271212
Bromodomain-containing protein 3Homo sapiens (human)Kd0.05991010
Bromodomain-containing protein 4Homo sapiens (human)EC500.120333
Bromodomain-containing protein 4Homo sapiens (human)Kd0.09123157
Calcium-dependent protein kinase 1Plasmodium falciparum 3D7Kd0.220011
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)Kd10.000033
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd15.000044
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)Kd10.000033
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)Kd10.000033
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)Kd10.000022
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)Kd10.000033
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)Kd10.000033
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd15.000044
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd14.000055
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd15.000044
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd16.666733
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd15.000044
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)Kd10.000033
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000011
Casein kinase I isoform alphaHomo sapiens (human)Kd16.666733
Casein kinase I isoform alpha-likeHomo sapiens (human)Kd10.000022
Casein kinase I isoform deltaHomo sapiens (human)Kd15.000044
Casein kinase I isoform epsilonHomo sapiens (human)Kd15.000044
Casein kinase I isoform gamma-1Homo sapiens (human)Kd15.000044
Casein kinase I isoform gamma-2Homo sapiens (human)Kd15.000044
Casein kinase I isoform gamma-3Homo sapiens (human)Kd15.000044
Casein kinase II subunit alphaHomo sapiens (human)Kd10.000033
Casein kinase II subunit alpha'Homo sapiens (human)Kd15.000044
Cell division control protein 2 homologPlasmodium falciparum 3D7Kd10.000011
Cell division cycle 7-related protein kinaseHomo sapiens (human)Kd30.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd15.000044
cGMP-dependent protein kinase 2Homo sapiens (human)Kd10.000033
Chain A, BCL-2-RELATED PROTEIN A1Homo sapiens (human)EC5070.600011
Chain A, Bromodomain testis-specific proteinHomo sapiens (human)Kd0.190111
Chain A, Bromodomain-containing protein 4Homo sapiens (human)Kd0.049011
Chain A, Mitogen-activated protein kinase 14Homo sapiens (human)Kd0.091417
Chain A, Slr1257 proteinSynechocystis sp. PCC 6803 substr. KazusaKd0.240011
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000011
Citron Rho-interacting kinaseHomo sapiens (human)Kd12.150044
CREB-binding proteinHomo sapiens (human)Kd9.600011
Cyclin-CHomo sapiens (human)Kd0.310011
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 11AHomo sapiens (human)Kd10.000033
Cyclin-dependent kinase 11BHomo sapiens (human)Kd10.000033
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 13Homo sapiens (human)Kd20.000022
Cyclin-dependent kinase 14Homo sapiens (human)Kd2.900033
Cyclin-dependent kinase 15Homo sapiens (human)Kd2.900022
Cyclin-dependent kinase 16Homo sapiens (human)Kd15.000044
Cyclin-dependent kinase 17Homo sapiens (human)Kd8.700044
Cyclin-dependent kinase 18Homo sapiens (human)Kd10.000033
Cyclin-dependent kinase 19Homo sapiens (human)Kd0.250033
Cyclin-dependent kinase 2Homo sapiens (human)Kd14.675044
Cyclin-dependent kinase 3Homo sapiens (human)Kd13.450044
Cyclin-dependent kinase 4Homo sapiens (human)Kd16.666733
Cyclin-dependent kinase 6Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 7Homo sapiens (human)Kd7.605044
Cyclin-dependent kinase 8Homo sapiens (human)Kd0.310044
Cyclin-dependent kinase 9Homo sapiens (human)Kd15.000044
Cyclin-dependent kinase-like 1Homo sapiens (human)Kd10.000011
Cyclin-dependent kinase-like 2Homo sapiens (human)Kd0.130022
Cyclin-dependent kinase-like 3Homo sapiens (human)Kd0.490022
Cyclin-dependent kinase-like 5Homo sapiens (human)Kd16.666733
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd12.900055
Cyclin-G-associated kinaseHomo sapiens (human)Kd15.000044
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000011
Cytochrome P450 1A1Homo sapiens (human)Kd19.100011
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)Kd10.000033
dCTP pyrophosphatase 1Homo sapiens (human)Kd30.000011
Death-associated protein kinase 1Homo sapiens (human)Kd10.000033
Death-associated protein kinase 2Homo sapiens (human)Kd10.000033
Death-associated protein kinase 3Homo sapiens (human)Kd10.000044
Delta-type opioid receptorMus musculus (house mouse)EC500.003012
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000011
Deoxycytidine kinaseHomo sapiens (human)Kd30.000011
Discoidin domain-containing receptor 2Homo sapiens (human)Kd0.328177
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000011
DNA topoisomerase 2-alphaHomo sapiens (human)Kd30.000011
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000011
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000011
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)Kd10.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd15.000044
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd15.000044
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd15.000044
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)Kd10.000033
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd15.095022
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd15.000044
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)Kd10.000011
Dual specificity protein kinase CLK1Homo sapiens (human)Kd14.375044
Dual specificity protein kinase CLK2Homo sapiens (human)Kd10.000033
Dual specificity protein kinase CLK3Homo sapiens (human)Kd15.000044
Dual specificity protein kinase CLK4Homo sapiens (human)Kd10.000033
Dual specificity protein kinase TTKHomo sapiens (human)Kd10.125044
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd15.000044
Dual specificity testis-specific protein kinase 2Homo sapiens (human)Kd30.000011
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd16.666733
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)Kd15.000044
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)Kd10.000022
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000011
eIF-2-alpha kinase GCN2Homo sapiens (human)Kd10.000033
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd30.000011
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000011
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000011
Ephrin type-A receptor 1Homo sapiens (human)Kd9.825044
Ephrin type-A receptor 2Homo sapiens (human)Kd8.160055
Ephrin type-A receptor 3Homo sapiens (human)Kd3.025044
Ephrin type-A receptor 4Homo sapiens (human)Kd8.060055
Ephrin type-A receptor 5Homo sapiens (human)Kd9.036766
Ephrin type-A receptor 6Homo sapiens (human)Kd0.318055
Ephrin type-A receptor 7Homo sapiens (human)Kd7.873366
Ephrin type-A receptor 8Homo sapiens (human)Kd1.824055
Ephrin type-B receptor 1Homo sapiens (human)Kd2.675044
Ephrin type-B receptor 2Homo sapiens (human)Kd8.925044
Ephrin type-B receptor 3Homo sapiens (human)Kd18.000045
Ephrin type-B receptor 4Homo sapiens (human)Kd7.860055
Ephrin type-B receptor 6Homo sapiens (human)Kd10.160033
Epidermal growth factor receptorHomo sapiens (human)Kd10.68972929
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd0.329455
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd20.000022
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000011
Ferrochelatase, mitochondrialHomo sapiens (human)Kd30.000011
Fibroblast growth factor receptor 1Homo sapiens (human)Kd8.180055
Fibroblast growth factor receptor 2Homo sapiens (human)Kd2.700033
Fibroblast growth factor receptor 3Homo sapiens (human)Kd6.983366
Fibroblast growth factor receptor 4Homo sapiens (human)Kd10.000033
Focal adhesion kinase 1Homo sapiens (human)Kd15.000044
G protein-coupled receptor kinase 4Homo sapiens (human)Kd10.000022
G protein-coupled receptor kinase 6Homo sapiens (human)Kd30.000011
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd30.000011
Glutamate receptor 1Homo sapiens (human)EC50792,445,056.07621220
Glutamate receptor 1Rattus norvegicus (Norway rat)EC5027.379967
Glutamate receptor 2Homo sapiens (human)EC50722,116,393.1444811
Glutamate receptor 2Rattus norvegicus (Norway rat)EC501,482,620,106.940045
Glutamate receptor 3Homo sapiens (human)EC502,264,128,594.871857
Glutamate receptor 3Rattus norvegicus (Norway rat)EC5054.804856
Glutamate receptor 4Homo sapiens (human)EC509,952,675,009.424424
Glutamate receptor 4Rattus norvegicus (Norway rat)EC5018.639245
Glutamate receptor ionotropic, kainate 1Homo sapiens (human)EC5057.333333
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)EC50129.163323
Glutamate receptor ionotropic, kainate 2Homo sapiens (human)EC5025.000022
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)EC5065.961523
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)EC501.406967
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)EC501.649634
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)EC500.960022
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)EC500.560022
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)EC500.285022
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)EC500.120011
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)EC500.120011
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd15.000044
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd15.000044
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000012
Heme oxygenase 2Homo sapiens (human)Kd30.000011
Hepatocyte growth factor receptorHomo sapiens (human)Kd10.000077
High affinity nerve growth factor receptorHomo sapiens (human)Kd10.500055
Homeodomain-interacting protein kinase 1Homo sapiens (human)Kd2.200022
Homeodomain-interacting protein kinase 2Homo sapiens (human)Kd1.700022
Homeodomain-interacting protein kinase 3Homo sapiens (human)Kd0.415022
Homeodomain-interacting protein kinase 4Homo sapiens (human)Kd0.003022
Hormonally up-regulated neu tumor-associated kinaseHomo sapiens (human)Kd10.000022
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)Kd10.000022
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)Kd10.000022
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd15.000044
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000011
Insulin receptorHomo sapiens (human)Kd15.000044
Insulin receptor-related proteinHomo sapiens (human)Kd10.000033
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd18.000045
Integrin alpha-IIbHomo sapiens (human)EC507.400011
Integrin beta-3Homo sapiens (human)EC507.400011
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000011
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)Kd10.000033
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd16.666733
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd15.000044
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd20.000022
Isoleucine--tRNA ligase, mitochondrialHomo sapiens (human)Kd30.000011
LacZ protein (plasmid)Escherichia coliEC5040.000011
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)Kd10.000022
Leukocyte tyrosine kinase receptorHomo sapiens (human)Kd10.000033
Leukotriene C4 synthaseCavia porcellus (domestic guinea pig)Kd10.000011
LIM domain kinase 1Homo sapiens (human)Kd7.400055
LIM domain kinase 2Homo sapiens (human)Kd14.900044
Long-chain-fatty-acid--CoA ligase 5Homo sapiens (human)Kd30.000011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)Kd0.028044
Macrophage-stimulating protein receptorHomo sapiens (human)Kd16.666733
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd15.000044
MAP kinase-activated protein kinase 3Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd15.000044
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd0.230033
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd0.160044
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd15.000044
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)Kd15.000044
Mast/stem cell growth factor receptor KitHomo sapiens (human)Kd0.18042323
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd15.000044
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)Kd10.000022
melanocortin receptor 4Homo sapiens (human)EC5050.000011
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd15.000044
Metabotropic glutamate receptor 1Homo sapiens (human)EC5045.237544
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)EC5013.15121012
Metabotropic glutamate receptor 2Homo sapiens (human)EC507.38491213
Metabotropic glutamate receptor 2Rattus norvegicus (Norway rat)EC508.7450810
Metabotropic glutamate receptor 3Homo sapiens (human)EC502.857255
Metabotropic glutamate receptor 3Rattus norvegicus (Norway rat)EC501.629434
Metabotropic glutamate receptor 4Homo sapiens (human)EC5014.933333
Metabotropic glutamate receptor 4Rattus norvegicus (Norway rat)EC506.3776810
Metabotropic glutamate receptor 5Homo sapiens (human)EC50163.550044
Metabotropic glutamate receptor 5Rattus norvegicus (Norway rat)EC506.4817810
Metabotropic glutamate receptor 6Homo sapiens (human)EC5098.300033
Metabotropic glutamate receptor 6Rattus norvegicus (Norway rat)EC5035.700055
Metabotropic glutamate receptor 7Homo sapiens (human)EC50625.295044
Metabotropic glutamate receptor 7Rattus norvegicus (Norway rat)EC50800.000023
Metabotropic glutamate receptor 8Mus musculus (house mouse)EC500.022011
Metabotropic glutamate receptor 8Rattus norvegicus (Norway rat)EC5014.493333
Microtubule-associated serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000022
MidasinHomo sapiens (human)Kd30.000011
Misshapen-like kinase 1Homo sapiens (human)Kd10.000022
Mitogen-activated protein kinase 1Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase 10Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase 11Homo sapiens (human)Kd5.181766
Mitogen-activated protein kinase 12Homo sapiens (human)Kd8.175044
Mitogen-activated protein kinase 13Homo sapiens (human)Kd6.600022
Mitogen-activated protein kinase 14Homo sapiens (human)Kd5.271766
Mitogen-activated protein kinase 15Homo sapiens (human)Kd7.534544
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase 4Homo sapiens (human)Kd10.000033
Mitogen-activated protein kinase 6Homo sapiens (human)Kd10.000033
Mitogen-activated protein kinase 7Homo sapiens (human)Kd10.000033
Mitogen-activated protein kinase 8Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase 9Homo sapiens (human)Kd12.200055
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd7.927733
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)Kd10.000033
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase kinase kinase 13Homo sapiens (human)Kd10.000022
Mitogen-activated protein kinase kinase kinase 15Homo sapiens (human)Kd10.000022
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)Kd0.099022
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd16.666733
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd0.187044
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd16.666733
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd15.000044
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd16.666733
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)Kd0.820044
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)Kd10.000033
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd13.700044
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd16.666733
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd18.000045
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd14.880045
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd7.300055
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd30.000011
Multifunctional protein ADE2Homo sapiens (human)Kd30.000011
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)Kd0.130033
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)Kd6.675044
Myosin light chain kinase 3Homo sapiens (human)Kd19.800022
Myosin light chain kinase family member 4Homo sapiens (human)Kd10.000033
Myosin light chain kinase, smooth muscleGallus gallus (chicken)Kd10.000011
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd14.000055
Myosin-10Homo sapiens (human)Kd30.000011
Myosin-14Homo sapiens (human)Kd30.000011
Myosin-IIIaHomo sapiens (human)Kd10.000033
Myosin-IIIbHomo sapiens (human)Kd9.033333
Myotonin-protein kinaseHomo sapiens (human)Kd10.000033
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000011
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd9.225044
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd13.333366
NT-3 growth factor receptorHomo sapiens (human)Kd0.600033
NUAK family SNF1-like kinase 1Homo sapiens (human)Kd10.000033
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd10.000033
Nuclear receptor subfamily 4 group A member 2Homo sapiens (human)EC505.100011
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd30.000011
nucleotide-binding oligomerization domain-containing protein 1 isoform 1Homo sapiens (human)EC502.110011
nucleotide-binding oligomerization domain-containing protein 2 isoform 1Homo sapiens (human)EC5020.000012
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Peripheral plasma membrane protein CASKHomo sapiens (human)Kd10.000011
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000011
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000011
Phosphatidylinositol 4-kinase betaHomo sapiens (human)Kd10.000022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)Kd10.000022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaHomo sapiens (human)Kd10.000022
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaHomo sapiens (human)Kd10.000033
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)Kd10.00002121
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)Kd10.000022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)Kd10.000022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)Kd10.000022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaHomo sapiens (human)Kd10.000033
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd20.000022
Phospholipid hydroperoxide glutathione peroxidaseHomo sapiens (human)EC508.818024
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd15.000044
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)Kd10.000033
Platelet-derived growth factor receptor alphaHomo sapiens (human)Kd0.062044
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd5.032266
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)Kd10.000011
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000011
Prostaglandin G/H synthase 2Homo sapiens (human)Kd10.000011
Protein delta homolog 1Homo sapiens (human)Kd10.000011
Protein kinase C alpha typeHomo sapiens (human)Kd20.000022
Protein kinase C beta typeHomo sapiens (human)Kd30.000011
Protein kinase C delta typeHomo sapiens (human)Kd15.000044
Protein kinase C epsilon typeHomo sapiens (human)Kd10.000033
Protein kinase C eta typeHomo sapiens (human)Kd10.000033
Protein kinase C iota typeHomo sapiens (human)Kd20.000022
Protein kinase C theta typeHomo sapiens (human)Kd15.000044
Protein kinase C zeta typeHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd15.000044
Protein-tyrosine kinase 6Homo sapiens (human)Kd15.000044
ProthrombinHomo sapiens (human)EC507.400011
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd0.03021212
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)Kd10.000033
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd15.000044
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000011
Pyridoxal kinaseHomo sapiens (human)Kd30.000011
Rab-like protein 3Homo sapiens (human)Kd30.000011
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd15.000044
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd15.000044
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd15.000044
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)Kd0.230033
Ras-related protein Rab-10Homo sapiens (human)Kd30.000011
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000011
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000011
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)Kd10.000033
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)Kd10.000022
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)Kd10.000022
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000033
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd7.360055
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 4Homo sapiens (human)Kd10.000022
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd0.14662828
recombinase AMycobacterium tuberculosis H37RvEC500.597622
Rho-associated protein kinase 1Homo sapiens (human)Kd16.666733
Rho-associated protein kinase 2Homo sapiens (human)Kd16.666733
Rhodopsin kinase GRK1Homo sapiens (human)Kd10.000022
Rhodopsin kinase GRK7Homo sapiens (human)Kd10.000022
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd12.857177
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)Kd10.000066
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd15.000044
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd12.857177
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd12.857177
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd11.785777
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd16.666733
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd30.000011
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000011
RuvB-like 2Homo sapiens (human)Kd22.000011
S-adenosylmethionine synthase isoform type-2Homo sapiens (human)Kd30.000011
Septin-9Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 10Homo sapiens (human)Kd5.121766
Serine/threonine-protein kinase 16Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase 17AHomo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 17BHomo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 24Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase 25Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 26Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase 3Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase 32AHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase 32BHomo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 32CHomo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 33Homo sapiens (human)Kd2.400033
Serine/threonine-protein kinase 35Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase 36Homo sapiens (human)Kd4.200044
Serine/threonine-protein kinase 38Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase 38-likeHomo sapiens (human)Kd10.000033
Serine/threonine-protein kinase 4Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ATRHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)EC500.003011
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd4.085588
Serine/threonine-protein kinase BRSK1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase BRSK2Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase Chk2Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase D1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase D2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase D3Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase DCLK1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase DCLK2Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase DCLK3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd16.666733
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase LATS2Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase MAKHomo sapiens (human)Kd10.000022
Serine/threonine-protein kinase MARK1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd15.000044
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd15.000044
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd15.000044
Serine/threonine-protein kinase mTORHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase N1Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase N2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase N3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase Nek11Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd20.000022
Serine/threonine-protein kinase Nek4Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase Nek5Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase Nek6Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase Nek7Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase NIM1Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd7.980044
Serine/threonine-protein kinase OSR1Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase PAK 1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase PAK 3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase PAK 5Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd18.000045
Serine/threonine-protein kinase pim-3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PknBMycobacterium tuberculosis H37RvKd10.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PLK2Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase PLK3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd9.380055
Serine/threonine-protein kinase PRP4 homologHomo sapiens (human)Kd10.000022
Serine/threonine-protein kinase receptor R3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase RIO1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase RIO2Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase RIO3Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase SBK1Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase Sgk3Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase SIK1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd15.000044
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd16.666733
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd18.000045
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd10.910044
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd15.270022
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd11.800033
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd20.000034
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)Kd0.280044
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)Kd10.000033
Serine/threonine-protein kinase ULK1Homo sapiens (human)Kd16.666733
Serine/threonine-protein kinase ULK2Homo sapiens (human)Kd10.000022
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd16.666733
Serine/threonine-protein kinase VRK2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd16.666733
SNF-related serine/threonine-protein kinaseHomo sapiens (human)Kd10.000011
SRSF protein kinase 1Homo sapiens (human)Kd10.000033
SRSF protein kinase 2Homo sapiens (human)Kd10.000033
SRSF protein kinase 3Homo sapiens (human)Kd10.000022
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd6.920055
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000011
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)Kd10.000022
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrialHomo sapiens (human)Kd30.000012
Testis-specific serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000033
TGF-beta receptor type-1Homo sapiens (human)Kd15.000044
TGF-beta receptor type-2Homo sapiens (human)Kd14.225044
Thyroid hormone receptor-associated protein 3Homo sapiens (human)Kd30.000011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd14.475044
Transient receptor potential cation channel subfamily A member 1Homo sapiens (human)EC503.000011
Transient receptor potential cation channel subfamily M member 6Homo sapiens (human)Kd10.000011
Tubulin alpha-1A chainRattus norvegicus (Norway rat)Kd10.000011
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd2.12884040
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd11.666756
Tyrosine-protein kinase BlkHomo sapiens (human)Kd10.000033
Tyrosine-protein kinase BTKHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase CSKHomo sapiens (human)Kd13.225044
Tyrosine-protein kinase FerHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase FgrHomo sapiens (human)Kd9.266733
Tyrosine-protein kinase FRKHomo sapiens (human)Kd4.692977
Tyrosine-protein kinase FynHomo sapiens (human)Kd14.600044
Tyrosine-protein kinase HCKHomo sapiens (human)Kd14.625044
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)Kd10.000033
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd13.333366
Tyrosine-protein kinase JAK2Homo sapiens (human)Kd10.000033
Tyrosine-protein kinase JAK3Homo sapiens (human)Kd9.100033
Tyrosine-protein kinase LckHomo sapiens (human)Kd9.000055
Tyrosine-protein kinase LynHomo sapiens (human)Kd9.750044
Tyrosine-protein kinase MerHomo sapiens (human)Kd10.200044
Tyrosine-protein kinase receptor Tie-1Homo sapiens (human)Kd0.068033
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)Kd10.000033
Tyrosine-protein kinase receptor UFOHomo sapiens (human)Kd4.500033
Tyrosine-protein kinase SrmsHomo sapiens (human)Kd9.800033
Tyrosine-protein kinase SYKHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase TecHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase TXKHomo sapiens (human)Kd10.000033
Tyrosine-protein kinase YesHomo sapiens (human)Kd15.000044
Tyrosine-protein kinase ZAP-70Homo sapiens (human)Kd10.000033
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000011
Uncharacterized protein FLJ45252Homo sapiens (human)Kd30.000011
Uncharacterized serine/threonine-protein kinase SBK3Homo sapiens (human)Kd10.000022
Vascular endothelial growth factor receptor 1 Homo sapiens (human)Kd0.031044
Vascular endothelial growth factor receptor 2Homo sapiens (human)EC500.500011
Vascular endothelial growth factor receptor 2Homo sapiens (human)Kd0.066066
Vascular endothelial growth factor receptor 3Homo sapiens (human)Kd0.063455
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000011
Voltage-dependent anion-selective channel protein 2Homo sapiens (human)Kd0.100011
Wee1-like protein kinaseHomo sapiens (human)Kd18.000045
Wee1-like protein kinase 2Homo sapiens (human)Kd10.000022

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Bcl-2-like protein 11Homo sapiens (human)AC5041.910011
Bromodomain-containing protein 4Homo sapiens (human)DC505.000011
Carbonic anhydrase 1Homo sapiens (human)KA6.430011
Carbonic anhydrase 2Homo sapiens (human)KA100.000011
Carbonic anhydrase-like protein, putativeTrypanosoma cruzi strain CL BrenerKA100.000011
Chain A, BCL-2-RELATED PROTEIN A1Homo sapiens (human)AC5082.453366
Cytochrome P450 1A1Homo sapiens (human)Km803.000011
Cytochrome P450 1A1Rattus norvegicus (Norway rat)Ks870.000011
Cytochrome P450 1A2Homo sapiens (human)Km120.000011
Cytochrome P450 2B1Rattus norvegicus (Norway rat)Ks800.000011
DNA damage-binding protein 1Homo sapiens (human)DC505.000011
Excitatory amino acid transporter 1Homo sapiens (human)Km8.550022
Excitatory amino acid transporter 2Homo sapiens (human)Km21.000022
Excitatory amino acid transporter 3Homo sapiens (human)Km17.450022
Excitatory amino acid transporter 3 Rattus norvegicus (Norway rat)Ks5.100011
Glutamate racemaseEnterococcus faecalis V583Km1,200.000011
Glutamate racemaseHelicobacter pylori 26695Km5,176.666733
H3 histone acetyltransferaseCandida albicans SC5314AC503.260011
heat shock protein 90, putativePlasmodium falciparum 3D7AC504.554011
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)AC505.178011
HRAS, partialHomo sapiens (human)AC5013.903536
hypothetical protein CAALFM_CR05890CACandida albicans SC5314AC503.260011
interferon gamma precursorHomo sapiens (human)AC507.750011
Metabotropic glutamate receptor 1Homo sapiens (human)Activity1.000011
Metabotropic glutamate receptor 2Homo sapiens (human)Activity4.000011
Metabotropic glutamate receptor 3Homo sapiens (human)Activity9.000011
Metabotropic glutamate receptor 4Homo sapiens (human)Activity12.000011
Metabotropic glutamate receptor 5Homo sapiens (human)Activity4.000011
Metabotropic glutamate receptor 6Homo sapiens (human)Activity20.000011
Metabotropic glutamate receptor 7Homo sapiens (human)Activity5,400.000011
PAX8Homo sapiens (human)AC500.323011
Prostaglandin G/H synthase 2Homo sapiens (human)INH26.000011
Protein cereblonHomo sapiens (human)DC505.000011
replicative DNA helicaseMycobacterium tuberculosis H37RvAC501.248522
Sulfotransferase 1A1 Rattus norvegicus (Norway rat)Km92.000011
toxin BClostridioides difficile 630AC5020.870011
UDP-glucuronosyltransferase 1-6Homo sapiens (human)Km2,200.000011
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)Km9,400.000011
UDP-glucuronosyltransferase 1A9Homo sapiens (human)Km20,900.000011
Vascular endothelial growth factor receptor 2Homo sapiens (human)INH100.000011