A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
| Member | Definition | Class |
|---|
| aee 788 | A 6-{4-[(4-ethylpiperazin-1-yl)methyl]phenyl}-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine which adopts an R-configuration. It is a potent inhibitor of human EGFR, VEGFR and HER2 receptor tyrosine kinases and exhibits anticancer and antiangiogenic activity. | AEE788 |
| ancistroealaine a | An isoquinoline alkaloid that is (3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinoline substituted by a 4,5-dimethoxy-7-methylnaphthalen-1-yl group at position 5. It is isolated from the leaves of Ancistrocladus tanzaniensis and exhibits antiplasmodial, antileishmanial and antitrypanocidal activities. | ancistrotanzanine B |
| anonaine | An aporphine alkaloid that exhibits anti-cancer, trypanocidal and antiplasmodial activites. | (-)-annonaine |
| astragalin | A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. | kaempferol 3-O-beta-D-glucoside |
| cubebin | A lignan that consists of tetrahydrofuran-2-ol substituted by two 1,3-benzodioxol-5-ylmethyl groups at positions 3 and 4 respectively (the 2S,3R,4R stereoisomer). It is isolated from the leaves of Piper nigrum and exhibits analgesic, anti-inflammatory, antimicrobial and trypanocidal activities. | (-)-cubebin |
| dehydrocostus lactone | An organic heterotricyclic compound and guaianolide sesquiterpene lactone that is acrylic acid which is substituted at position 2 by a 4-hydroxy-3,8-bis(methylene)decahydoazulen-5-yl group and in which the hydroxy group and the carboxy group have undergone formal condensation to afford the corresponding gamma-lactone. | dehydrocostus lactone |
| diminazene | A triazene derivative that is triazene in which each of the terminal nitrogens is substituted by a 4-carbamimidoylphenyl group. | diminazene |
| diminazene aceturate | An N-acetylglycinate salt resulting from the reaction of diminazene with 2 mol eq. of N-acetylglycine. | diminazene diaceturate |
| eflornithine | A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2. | eflornithine |
| ergosterol-5,8-peroxide | An ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities. | ergosterol peroxide |
| ethidium bromide | The organic bromide salt of ethidium. | ethidium bromide |
| hinokinin | A lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 3,4-methylenedioxybenzyl group at positions 3 and 4 (the 3R,4R-diastereoisomer). | hinokinin |
| komaroviquinone | A tetracyclic diterpenoid isolated from Dracocephalum komarovii and has been shown to exhibit trypanocidal activity. | komaroviquinone |
| nucleocidin | A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. | nucleocidin |
| pentamidine | A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. | pentamidine |
| pentamidine isethionate | An organosulfonate salt obtained by reaction of pentamidine with two equivalents of 2-hydroxyethylsulfonic acid. | pentamidine isethionate |
| posaconazole | An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug. | posaconazole |
| quercetin 3-o-glucoside-7-o-rhamnoside | A quercetin O-glucoside that is quercetin attached to beta-D-glucopyranosyl residue at position 3 and a alpha-L-rhamnopyranosyl residue at position 7 via glycosidic linkages. Isolated from the aerial parts of Delphinium staphisagria, it exhibits trypanocidal activity. | petiolaroside |
| salicylhydroxamic acid | A hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2. | salicylhydroxamic acid |
| suramin | A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years. | suramin |
| suramin sodium | An organic sodium salt that is the hexasodium salt of suramin. It is an FDA approved drug for African sleeping sickness and river blindness. | suramin sodium |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 24.9054 | 1 | 2 |
| 67.9K protein | Vaccinia virus | Potency | 11.0691 | 2 | 5 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 34.7624 | 3 | 15 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.5604 | 1 | 3 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 6.0374 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 21.0384 | 11 | 45 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 22.4240 | 2 | 6 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.5750 | 1 | 1 |
| Ataxin-2 | Homo sapiens (human) | Potency | 15.8562 | 1 | 7 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 7.0795 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 15.3043 | 2 | 9 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 20.5348 | 2 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 17.5886 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 17.3999 | 3 | 9 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 5.3986 | 2 | 4 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 5.5000 | 1 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 25.5693 | 3 | 6 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 28.1838 | 1 | 1 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 23.4336 | 2 | 6 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 17.9008 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 14.3880 | 2 | 4 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 20.3326 | 3 | 7 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 1.2589 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 4.9214 | 2 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 14.3880 | 2 | 4 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 77.9634 | 2 | 3 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 10.9321 | 3 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 16.4333 | 1 | 3 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 3.4671 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 8.1548 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 0.6547 | 1 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 21.2685 | 1 | 6 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 21.6035 | 2 | 3 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 36.3378 | 2 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 9.2279 | 2 | 9 |
| endonuclease IV | Escherichia coli | Potency | 9.2961 | 2 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 23.4178 | 10 | 50 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 8.5858 | 1 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 5.1567 | 6 | 37 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 2.9129 | 1 | 5 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 7.3075 | 4 | 9 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 22.4154 | 3 | 8 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 14.7667 | 2 | 2 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 21.3584 | 1 | 3 |
| G | Vesicular stomatitis virus | Potency | 16.4333 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| galactokinase | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 8.1548 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 16.9156 | 2 | 2 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 11.6910 | 2 | 12 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 5.9081 | 4 | 9 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 8.9125 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 16.6488 | 2 | 7 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 8.9125 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 8.9125 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 0.0041 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 25.0654 | 1 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 7.8758 | 1 | 4 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 15.6495 | 2 | 6 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 80.0112 | 2 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 25.5546 | 1 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 16.4333 | 1 | 3 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 21.5655 | 1 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 26.0297 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 14.5903 | 3 | 5 |
| IDH1 | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 62.9480 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 16.4333 | 1 | 6 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 8.2852 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 8.2852 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 18.6038 | 2 | 9 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 6.8612 | 2 | 5 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 2.5119 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 27.5362 | 2 | 2 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 15.8489 | 1 | 1 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 9.9237 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 19.0591 | 2 | 8 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 1.5849 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.3548 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 15.7579 | 3 | 13 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 18.4675 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 18.8336 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 19.3072 | 2 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 21.9381 | 2 | 10 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 75.6863 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 21.9384 | 2 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 43.7386 | 4 | 8 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 31.0921 | 4 | 6 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 51.2487 | 1 | 3 |
| Platelet-activating factor receptor | Homo sapiens (human) | Potency | 22.0504 | 1 | 4 |
| polyprotein | Zika virus | Potency | 21.3584 | 1 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 7.8758 | 1 | 2 |
| PPM1D protein | Homo sapiens (human) | Potency | 19.6891 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 37.2243 | 1 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 56.2341 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 27.1857 | 1 | 3 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 0.7943 | 2 | 2 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 31.6228 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 17.3076 | 2 | 6 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 3.3546 | 1 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 30.9859 | 3 | 10 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 12.9147 | 4 | 8 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 10.9321 | 3 | 3 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 45.6522 | 2 | 3 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 45.6522 | 2 | 3 |
| Smad3 | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 62.9480 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 16.4833 | 2 | 4 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 12.2530 | 1 | 6 |
| TDP1 protein | Homo sapiens (human) | Potency | 1.6828 | 2 | 12 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 0.1259 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 9.4662 | 1 | 1 |
| Thrombopoietin | Homo sapiens (human) | Potency | 3.9811 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 35.3992 | 2 | 14 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 28.6608 | 4 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 27.3467 | 6 | 16 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 37.5780 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 0.0101 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 25.3618 | 2 | 5 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 21.7761 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 15.6968 | 1 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 41.3585 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 17.9382 | 1 | 6 |
| Vpr | Human immunodeficiency virus 1 | Potency | 33.5384 | 1 | 2 |
| WRN | Homo sapiens (human) | Potency | 2.9935 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 133.7333 | 4 | 6 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 160.0000 | 3 | 5 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 1.6390 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.4680 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 3.2780 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.7170 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 3.2780 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.7170 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 133.7333 | 4 | 6 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 160.0000 | 3 | 5 |
| Acid-sensing ion channel 1 | Mus musculus (house mouse) | IC50 | 51.0500 | 2 | 2 |
| Acid-sensing ion channel 2 | Mus musculus (house mouse) | IC50 | 107.1000 | 2 | 2 |
| Acrosin | Sus scrofa (pig) | Ki | 2.3000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 60.5000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 3.6520 | 2 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 2.1960 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 1.3750 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.5160 | 1 | 1 |
| Alternative oxidase, mitochondrial | Trypanosoma brucei brucei | IC50 | 5.9300 | 1 | 1 |
| Amiloride-sensitive amine oxidase [copper-containing] | Homo sapiens (human) | Ki | 0.1515 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 0.7930 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 15.7215 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 12.8802 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 8.4000 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| ATP-dependent 6-phosphofructokinase | Trypanosoma brucei brucei | IC50 | 3.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 319.0250 | 3 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 6.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.0049 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.1680 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 5.5912 | 1 | 1 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 0.4237 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | IC50 | 30.0000 | 1 | 2 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Homo sapiens (human) | IC50 | 0.3100 | 1 | 1 |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | IC50 | 0.0210 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 75.0000 | 3 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 68.2400 | 5 | 5 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 19.8667 | 3 | 3 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 28.2786 | 8 | 8 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.3730 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | IC50 | 68.0000 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 19.0000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 3.9980 | 1 | 1 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 18.1000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.3580 | 1 | 1 |
| Diamine acetyltransferase 1 | Homo sapiens (human) | Ki | 2.2000 | 1 | 2 |
| DNA primase | Mycobacterium tuberculosis CDC1551 | IC50 | 8.2000 | 1 | 1 |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| Dual specificity protein phosphatase 5 | Homo sapiens (human) | Ki | 0.0250 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | Rattus norvegicus (Norway rat) | Ki | 300.0000 | 2 | 2 |
| Ectonucleoside triphosphate diphosphohydrolase 2 | Rattus norvegicus (Norway rat) | Ki | 65.4000 | 2 | 2 |
| Ectonucleoside triphosphate diphosphohydrolase 3 | Rattus norvegicus (Norway rat) | Ki | 12.7000 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 8 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.0020 | 3 | 3 |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Excitatory amino acid transporter 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Excitatory amino acid transporter 3 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Furin | Homo sapiens (human) | Ki | 5.4200 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 112.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 0.7200 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Lactoperoxidase | Bos taurus (cattle) | IC50 | 1.2000 | 1 | 2 |
| Mitochondrial 2-oxodicarboxylate carrier | Homo sapiens (human) | IC50 | 252.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 1.7033 | 3 | 3 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 6.5500 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 1.4250 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 0.5070 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 1.5800 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 0.2200 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | IC50 | 2.8850 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 2.0730 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 14.0000 | 2 | 2 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 240.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 1.3857 | 7 | 7 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 1.1750 | 4 | 4 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 20.6000 | 8 | 8 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 38.4000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 33.0000 | 1 | 1 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 6.3000 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | IC50 | 15.7215 | 1 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | Ki | 12.8802 | 1 | 1 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Ki | 39.0000 | 1 | 1 |
| P2X purinoceptor 2 | Rattus norvegicus (Norway rat) | IC50 | 21.9054 | 1 | 2 |
| P2Y purinoceptor 11 | Homo sapiens (human) | Ki | 0.2071 | 2 | 2 |
| P2Y purinoceptor 2 | Homo sapiens (human) | IC50 | 75.0000 | 2 | 2 |
| P2Y purinoceptor 6 | Homo sapiens (human) | IC50 | 27.0000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 70.0000 | 1 | 1 |
| Plasminogen | Homo sapiens (human) | IC50 | 28.4000 | 3 | 5 |
| polyadenylate-binding protein 1 | Homo sapiens (human) | IC50 | 53.1900 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 30.0998 | 2 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 15.8054 | 4 | 4 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 12.8802 | 1 | 1 |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | IC50 | 239.2860 | 5 | 5 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | IC50 | 582.0000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Protein S100-B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 1 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 2 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Protein tyrosine phosphatase type IVA 3 | Homo sapiens (human) | IC50 | 35.8333 | 3 | 3 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 0.7400 | 1 | 1 |
| putative polyprotein | | IC50 | 2.4395 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 0.0040 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | IC50 | 0.0020 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | IC50 | 0.0020 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 8.8000 | 3 | 3 |
| RmtA | Aspergillus nidulans | IC50 | 5.9000 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 29.4000 | 1 | 1 |
| Signal transducer and activator of transcription 1-alpha/beta | Homo sapiens (human) | IC50 | 9.1000 | 1 | 1 |
| Signal transducer and activator of transcription 3 | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| Signal transducer and activator of transcription 5A | Homo sapiens (human) | IC50 | 9.4000 | 1 | 1 |
| Signal transducer and activator of transcription 5B | Homo sapiens (human) | IC50 | 10.4000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | IC50 | 20.6000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 7.8363 | 2 | 3 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 2.5100 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 70.3247 | 2 | 3 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 2.1960 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 187.5000 | 1 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 22.1000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 9.5000 | 1 | 1 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | IC50 | 0.9210 | 2 | 2 |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | IC50 | 0.4640 | 2 | 2 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 1.1600 | 1 | 1 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 2.5900 | 13 | 13 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 0.8300 | 1 | 1 |
| Thyroid peroxidase | Homo sapiens (human) | IC50 | 1.2000 | 1 | 2 |
| Transcriptional activator Myb | Gallus gallus (chicken) | IC50 | 9.5450 | 1 | 2 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 0.0153 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 9.7600 | 1 | 1 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Escherichia coli K-12 | IC50 | 50.0000 | 1 | 1 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Pseudomonas aeruginosa PAO1 | IC50 | 50.0000 | 1 | 1 |
| Uracil nucleotide/cysteinyl leukotriene receptor | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 43.3333 | 1 | 3 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 0.0590 | 1 | 1 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.0770 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 14-alpha sterol demethylase | Aspergillus fumigatus | Kd | 0.1020 | 2 | 2 |
| 14-alpha sterol demethylase | Aspergillus niger | Kd | 0.1310 | 1 | 1 |
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 1.0060 | 1 | 1 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 16.1210 | 1 | 1 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| bcl-2-like protein 11 isoform 1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bile acid receptor | Mus musculus (house mouse) | EC50 | 0.8500 | 1 | 1 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 0.4950 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chain A, BCL-2-RELATED PROTEIN A1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 28.1920 | 1 | 1 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 9.4300 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 26.3990 | 1 | 1 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 0.0599 | 3 | 8 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 5.2230 | 1 | 1 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | Kd | 0.0810 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 0.6320 | 1 | 1 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 21.7700 | 1 | 1 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 13.6380 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 2.1890 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 3.5340 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 7.9790 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 50.2140 | 1 | 1 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Multidrug resistance protein MdtK | Escherichia coli K-12 | Kd | 9.8000 | 1 | 1 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | Kd | 2.0000 | 1 | 1 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | EC50 | 72.8000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 1.3000 | 1 | 1 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| P2X purinoceptor 1 | Rattus norvegicus (Norway rat) | EC50 | 1.0000 | 1 | 1 |
| P2X purinoceptor 2 | Rattus norvegicus (Norway rat) | EC50 | 10.4000 | 1 | 1 |
| P2X purinoceptor 3 | Homo sapiens (human) | EC50 | 8.9500 | 2 | 2 |
| P2X purinoceptor 4 | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| P2X purinoceptor 5 | Rattus norvegicus (Norway rat) | EC50 | 4.0000 | 1 | 1 |
| P2X purinoceptor 6 | Rattus norvegicus (Norway rat) | EC50 | 100.0000 | 1 | 1 |
| P2X purinoceptor 7 | Homo sapiens (human) | EC50 | 92.0000 | 1 | 1 |
| P2Y purinoceptor 1 | Meleagris gallopavo (turkey) | EC50 | 10.0000 | 1 | 1 |
| P2Y purinoceptor 11 | Homo sapiens (human) | EC50 | 16.0000 | 1 | 1 |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | EC50 | 4.0000 | 1 | 1 |
| P2Y purinoceptor 2 | Homo sapiens (human) | EC50 | 48.0000 | 1 | 1 |
| P2Y purinoceptor 4 | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 9.3830 | 1 | 1 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein S100-B | Homo sapiens (human) | Kd | 1.0000 | 1 | 1 |
| Protein S100-B | Rattus norvegicus (Norway rat) | Kd | 47.0000 | 2 | 2 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Mus musculus (house mouse) | EC50 | 0.8500 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 42.5500 | 1 | 1 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 38.0880 | 1 | 1 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 41.7950 | 1 | 1 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 99.2320 | 1 | 1 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Sterol 14-alpha demethylase | Aspergillus fumigatus Af293 | Kd | 2.6900 | 1 | 1 |
| Sterol 14-alpha demethylase | Trypanosoma cruzi strain CL Brener | Kd | 0.0390 | 2 | 2 |
| Sterol 14-alpha-demethylase | Aspergillus flavus AF70 | Kd | 0.1310 | 1 | 1 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 1.0910 | 1 | 1 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 14.9240 | 1 | 1 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 17.1520 | 1 | 1 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 65.1580 | 1 | 1 |