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chlorinated steroid
A steroid which is substituted with one or more chlorine atoms in any position.
ChEBI ID: 77175
Members (8)
| Member | Definition | Role |
|---|---|---|
| beclomethasone | A 17alpha-hydroxy steroid that is prednisolone in which the hydrogens at the 9alpha and 16beta positions are substituted by a chlorine and a methyl group, respectively. | beclomethasone |
| beclomethasone dipropionate | A steroid ester comprising beclomethasone having propionyl groups at the 17- and 21-positions. | beclomethasone dipropionate |
| clobetasol | A 3-oxo-Delta(1),Delta(4)-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis. | clobetasol |
| clobetasol propionate | The 17-O-propionate ester of clobetasol. A potent corticosteroid, it is used to treat various skin disorders, including exzema and psoriasis. | clobetasol propionate |
| clocortolone pivalate | The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders. | clocortolone pivalate |
| cyproterone | cyproterone | |
| cyproterone acetate | A steroid ester resulting from the formal condensation of the carboxy group of acetic acid with the 17-hydroxy group of cyproterone. It is an antiandrogenic drug which has recently been recognized to promote the occurrence and growth of intracranial meningiomas. | cyproterone acetate |
| sch 22219 | A prednisolone compound having an alpha-chloro substituent at the 7-position, an alpha-methyl substituent at the 16-position and O-propanoyl groups at the 17- and 21-positions. | alclometasone dipropionate |
Research
Studies (4,106)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,549 (37.73) | 18.7374 |
| 1990's | 786 (19.14) | 18.2507 |
| 2000's | 786 (19.14) | 29.6817 |
| 2010's | 772 (18.80) | 24.3611 |
| 2020's | 213 (5.19) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 904 (17.42%) | 5.53% |
| Reviews | 400 (7.71%) | 6.00% |
| Case Studies | 809 (15.59%) | 4.05% |
| Observational | 14 (0.27%) | 0.25% |
| Other | 3,063 (59.02%) | 84.16% |