Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
| Member | Definition | Class |
|---|
| 1-hydroxyethyl radical | An organic anion that is the conjugate base of ethanol. | ethoxide |
| 1-phospho-5-s-methylthioribulose | Dianion of S-methyl-5-thio-D-ribulose 1-phosphate. | S-methyl-5-thio-D-ribulose 1-phosphate(2-) |
| 2-(4-methyl-1,3-thiazol-5-yl)ethanol | A 1,3-thiazole that is thiazole substituted by a methyl group at position 4 and a 2-hydroxyethyl group at position 5. | 5-(2-hydroxyethyl)-4-methylthiazole |
| 2-furoic acid | A furoic acid having the carboxylic acid group located at position 2. | 2-furoic acid |
| 2-keto-4-hydroxyglutarate | An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 4-hydroxy-2-oxoglutaric acid. | 4-hydroxy-2-oxoglutarate(2-) |
| 2-methylbutanal | A methylbutanal in which the methyl substituent is at position 2. | 2-methylbutanal |
| 2-methylbutanol | A primary alcohol that is isopentane substituted by a hydroxy group at position 1. | 2-methylbutan-1-ol |
| 2-phenylethyl acetate | The acetate ester of 2-phenylethanol. | phenethyl acetate |
| 2,3-oxidosqualene | A 2,3-epoxysqualene in which the chiral centre has S configuration. It is converted into lanosterol by lanosterol synthase (EC 5.4.99.7) in a key rate-limiting step in the biosynthesis of chloesterol, steroid hormones, and vitamin D. | (S)-2,3-epoxysqualene |
| 2'-deoxy cyclic amp | | 3',5'-cyclic dAMP |
| 2'-deoxyadenosine | A purine 2'-deoxyribonucleoside having adenine as the nucleobase. | 2'-deoxyadenosine |
| 3-dehydroshikimate | A monocarboxylic acid anion that is the conjugate base of 3-dehydroshikimic acid, arising from deprotonation of the carboxy group. | 3-dehydroshikimate |
| 3-mercaptohexanol | An alkanethiol that is hexane substituted at positions 1 and 3 by hydroxy and sulfanyl groups respectively. | 3-mercaptohexanol |
| 3-mercaptohexyl acetate | An acetate ester obtained by formal O-acetylation of 3-mercaptohexanol. | 3-mercaptohexyl acetate |
| 3-methylhistidine | A L-histidine derivative that is L-histidine substituted by a methyl group at position 3 on the imidazole ring. | N(pros)-methyl-L-histidine zwitterion; N(pros)-methyl-L-histidine |
| 4-aminobenzoic acid | An aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid. | 4-aminobenzoate |
| 4-hydroxy-2-ethyl-5-methyl-3(2h)-furanone | A member of the class of furans that is furan-3(2H)-one carrying additional ethyl, hydroxy and methyl substituents at positions 2, 4 and 5 respectively. A key aroma compound in soy sauce and fish sauce. | 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone |
| 4-methyl-4-sulfanylpentan-2-one | An alkylthiol that is 4-methylpentan-2-one substituted at position 4 by a mercapto group. | 4-mercapto-4-methylpentan-2-one |
| 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol | A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol. | 14-demethyllanosterol |
| 4,4-dimethylcholesta-8,14,24-trienol | | 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol |
| 5-amino-6-ribitylamino-2,4-(1h,3h)pyrimidinedione | An aminouracil that is D-ribitol in which the hydroxy group at position 1 is substituted by the 6-amino group of 5,6-diaminouracil. Early intermediate in bacterial riboflavin synthesis. | 5-amino-6-(D-ribitylamino)uracil |
| 5,6,7,8-tetrahydrofolic acid | | 5,6,7,8-tetrahydrofolic acid |
| 5'-methylthioadenosine | Adenosine with the hydroxy group at C-5' substituted with a methylthio (methylsulfanyl) group. | 5'-S-methyl-5'-thioadenosine |
| 6-hydroxymethyl-7,8-dihydropterin | A dihydropterin that is 7,8-dihydropteridin-4-ol substituted at positions 2 and 6 by amino and hydroxymethyl groups respectively. | 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol; 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one |
| 6-phosphogluconolactone | Dianion of 6-O-phosphono-D-glucono-1,5-lactone arising from deprotonation of the phosphate OH groups; major species at pH 7.3. | 6-O-phosphonato-D-glucono-1,5-lactone(2-) |
| 7-keto-8-aminopelargonic acid | The 8-amino-7-oxo derivative of nonanoic acid. | 8-amino-7-oxononanoic acid zwitterion; 8-amino-7-oxononanoic acid |
| 7,8-dihydroneopterin | A neopterin where positions C-7 and C-8 have been hydrogenated. | 7,8-dihydroneopterin |
| acetaldehyde | The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke. | acetaldehyde |
| acetylcarnitine | An O-acyl-L-carnitine where the acyl group specified is acetyl. It facilitates movement of acetyl-CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids. | O-acetyl-L-carnitine |
| adenine | The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. | adenine |
| aica ribonucleotide | A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. | AICA ribonucleotide |
| allantoin | An imidazolidine-2,4-dione that is 5-aminohydantoin in which a carbamoyl group is attached to the exocyclic nitrogen. | allantoin |
| allysine | An optically active form of allysine having L-configuration. | L-allysine zwitterion; L-allysine |
| alpha-ketoisovalerate | A 2-oxo monocarboxylic acid that is the 2-oxo derivative of isovaleric acid. | 3-methyl-2-oxobutanoic acid |
| aminolevulinic acid | The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. | 5-aminolevulinic acid; 5-ammoniolevulinate |
| asparagine | An optically active form of asparagine having L-configuration. | L-asparagine zwitterion; L-asparagine |
| biotin | An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. | biotin |
| biotinate | Conjugate base of biotin arising from deprotonation of the carboxy group. | biotinate |
| caprylates | A straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (caprylic acid); believed to block adipogenesis. | octanoate |
| cerotate | The conjugate base of cerotic acid. | cerotate |
| choline | A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. | choline |
| chorismic acid | The (3R,4R)-stereoisomer of 5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid. | chorismic acid |
| citrulline | The L-enantiomer of citrulline. | L-citrulline zwitterion; L-citrulline |
| copper histidine | An optically active form of histidine having D-configuration. | D-histidine zwitterion; D-histidine |
| cyclic amp | An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3. | 3',5'-cyclic AMP(1-) |
| cyclic gmp | A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. | 3',5'-cyclic GMP |
| cyclic imp | A 3',5'-cyclic purine nucleotide having hypoxanthine as the nucleobase. | 3',5'-cyclic IMP |
| cysteinylglycine | A dipeptide consisting of glycine having an L-cysteinyl attached to its alpha-amino group. It is an intermediate metabolite in glutathione metabolism. | L-cysteinylglycine zwitterion; L-cysteinylglycine |
| cysteinylglycine | The zwitterion of L-cysteinylglycine resulting from the transfer of a proton from the hydroxy group of glycine to the amino group of cysteine. Major microspecies at pH 7.3. | L-cysteinylglycine zwitterion; L-cysteinylglycine |
| cystine | The L-enantiomer of the sulfur-containing amino acid cystine. | L-cystine zwitterion; L-cystine |
| cytidine | A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond. | cytidine |
| cytidine diphosphate choline | A member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes. | CDP-choline |
| cytidine diphosphate choline | A member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes. | CDP-choline |
| cytosine | An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4. | cytosine |
| D-leucine | The D-enantiomer of leucine. | D-leucine zwitterion; D-leucine |
| d-ribo-phytosphingosine-1-phosphate | A phosphosphingolipid that is phytosphingosine bearing a phospho group at position 1. | phytosphingosine 1-phosphate |
| deoxycytidine | A pyrimidine 2'-deoxyribonucleoside having cytosine as the nucleobase. | 2'-deoxycytidine |
| deoxyguanosine | A purine 2'-deoxyribonucleoside having guanine as the nucleobase. | 2'-deoxyguanosine |
| deoxyguanosine triphosphate | A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase. | dGTP |
| deoxyinosine | A purine 2'-deoxyribonucleoside that is inosine in which the hydroxy group at position 2' is replaced by a hydrogen. | 2'-deoxyinosine |
| deoxyribose | A deoxypentose that is D-ribose in which the hydroxy group at position C-2 is replaced by hydrogen. | 2-deoxy-D-ribose |
| deoxyuridine | A pyrimidine 2'-deoxyribonucleoside having uracil as the nucleobase. | 2'-deoxyuridine |
| diacetyl | An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation. | butane-2,3-dione |
| diadenosine tetraphosphate | Tetraanion of P(1),P(4)-bis(5'-adenosyl) tetraphosphate arising from deprotonation of the tetraphosphate OH groups; major species at pH 7.3. | P(1),P(4)-bis(5'-adenosyl) tetraphosphate(4-) |
| dihydrolipoamide | | dihydrolipoamide |
| dihydroxyacetone | A ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. | dihydroxyacetone |
| dihydroxyacetone phosphate | A member of the class of glycerone phosphates that consists of glycerone bearing a single phospho substituent. | dihydroxyacetone phosphate |
| ergosterol | A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group. | ergosterol |
| ethyl acetate | The acetate ester formed between acetic acid and ethanol. | ethyl acetate |
| fecosterol | A 3beta-sterol having a 5alpha-ergostane skeleton with a methylidene group at C-24 and double bonds at the C-8 and C-24(28) positions. | fecosterol |
| formaldehyde | An aldehyde resulting from the formal oxidation of methanol. | formaldehyde |
| fumarates | A C4-dicarboxylate that is the E-isomer of but-2-enedioate(2-) | fumarate(2-) |
| gamma-aminobutyric acid | A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. | gamma-aminobutyric acid zwitterion; gamma-aminobutyric acid |
| gamma-glutamylcysteine | A molecular entity formed when L-cysteine amino group binds to the gamma-carbonyl of L-glutamic acid. | L-gamma-glutamyl-L-cysteine |
| gamma-guanidinobutyric acid | The 4-guanidino derivative of butanoic acid. | 4-guanidinobutanoic acid zwitterion; 4-guanidinobutanoic acid; 4-guanidinobutyric acid |
| glucosamine 6-phosphate | A 2-amino-2-deoxy-D-glucopyranose 6-phosphate that has an alpha-configuration at the anomeric position. | alpha-D-glucosamine 6-phosphate |
| glutamate | An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group | L-glutamate(1-) |
| glutamine | An optically active form of glutamine having L-configuration. | L-glutamine zwitterion; L-glutamine |
| glycerol | A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups. | glycerol |
| glycerylphosphorylcholine | A member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells. | choline alfoscerate |
| glyoxylic acid | A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom. | glyoxylic acid |
| guanine | A 2-aminopurine carrying a 6-oxo substituent. | guanine |
| hexadecanal | | hexadecanal |
| histidine | The L-enantiomer of the amino acid histidine. | L-histidine zwitterion; L-histidine |
| histidinol | An amino alcohol that is propanol substituted by 1H-imidazol-4-yl group at position 3 and an amino group at position 2 (the 2S stereoisomer). | L-histidinol |
| homoserine | The L-enantiomer of homoserine. | L-homoserine zwitterion; L-homoserine |
| hydrogen carbonate | The carbon oxoanion resulting from the removal of a proton from carbonic acid. | hydrogencarbonate |
| hydrogen sulfite | | hydrogensulfite |
| hydroxythreonine | A hydroxy-amino acid consisting of L-threonine having a hydroxy substituent at the 4-position. | 4-hydroxy-L-threonine zwitterion; 4-hydroxy-L-threonine |
| indol-3-yl pyruvic acid | A 2-oxo monocarboxylic acid that is pyruvic acid substituted by a 1H-indol-3-yl group at position 3. It has been found in Lycopersicon esculentum | 3-(indol-3-yl)pyruvic acid |
| indole-3-acetaldehyde | An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan. | indol-3-ylacetaldehyde |
| inosine | A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N(9)-glycosidic bond. | inosine |
| iron | | iron(2+) |
| isoamyl acetate | The acetate ester of isoamylol. | isoamyl acetate |
| isobutyl acetate | The acetate ester of isobutanol. | isobutyl acetate |
| isobutyl alcohol | An alkyl alcohol that is propan-1-ol substituted by a methyl group at position 2. | isobutanol |
| isobutyraldehyde | A member of the class of propanals that is propanal substituted by a methyl group at position 2. | isobutyraldehyde |
| isoleucine | The L-enantiomer of isoleucine. | L-isoleucine zwitterion; L-isoleucine |
| isopentyl alcohol | An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group. | isoamylol |
| isovalerylaldehyde | A methylbutanal that is butanal substituted by a methyl group at position 3. It occurs as a volatile constituent in olives. | 3-methylbutanal |
| kynurenic acid | A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4. | kynurenic acid |
| kynurenine | A kynurenine that has L configuration. | L-kynurenine zwitterion; L-kynurenine |
| lanosterol | A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. | lanosterol |
| leucine | The L-enantiomer of leucine. | L-leucine zwitterion; L-leucine |
| levocarnitine | The (R)-enantiomer of carnitine. | (R)-carnitine |
| lignoceroyl-coenzyme a | A very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of tetracosanoic (lignoceric) acid. It is an intermediate in the biosynthesis of unsaturated fatty acids. | tetracosanoyl-CoA |
| lipoamide | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia. | lipoamide |
| lysine | An L-alpha-amino acid; the L-isomer of lysine. | L-Lysine zwitterion; L-lysine |
| methionol | An alkyl sulfide that is propan-1-ol substituted by a methylsulfanyl group at position 3. It is a volatile compound found in wines and produced during fermentation. | 3-methylthiopropanol |
| methylmercaptan | | methanethiol |
| n-acetylalanine | An N-acetyl-L-amino acid that is L-alanine in which one of the hydrogens attached to the nitrogen is replaced by an acetyl group. | N-acetyl-L-alanine |
| n-acetylglutamic acid | An N-acyl-L-amino acid that is L-glutamic acid in which one of the amine hydrogens is substituted by an acetyl group. | N-acetyl-L-glutamic acid |
| n'-formylkynurenine | | N-formyl-L-kynurenine zwitterion; N-formyl-L-kynurenine |
| n(1)-methylnicotinamide | A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent. | 1-methylnicotinamide |
| nad | An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety. | NAD(1-) |
| niacinamide | A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. | nicotinamide |
| nicotinamide-beta-riboside | A pyridine nucleoside consisting of nicotinamide with a beta-D-ribofuranosyl moiety at the 1-position. | N-ribosylnicotinamide |
| nicotinate mononucleotide | Dianion of nicotinic acid D-ribonucleotide arising from deprotonation of carboxylic acid and phosphate functions. | nicotinate D-ribonucleotide(2-) |
| nicotinic acid adenine dinucleotide | | deamido-NAD(+) |
| o-succinylhomoserine | The O-succinyl derivative of L-homoserine. | O-succinyl-L-homoserine |
| pantolactone | A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a hydroxy group at position 3 and two methyl groups at position 4 (the R-stereoisomer). | (R)-pantolactone |
| phenylacetaldehyde | An aldehyde that consists of acetaldehyde bearing a methyl substituent; the parent member of the phenylacetaldehyde class of compounds. | phenylacetaldehyde |
| phenylacetic acid | A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group. | phenylacetic acid |
| phenylalanine | The L-enantiomer of phenylalanine. | L-phenylalanine zwitterion; L-phenylalanine |
| phenylethyl alcohol | A primary alcohol that is ethanol substituted by a phenyl group at position 2. | 2-phenylethanol |
| phosphopantothenic acid | An amidoalkyl phosphate that is the 4-phosphate derivative of (R)-pantothenic acid. | (R)-4'-phosphopantothenic acid |
| phytosphingosine | | phytosphingosine |
| plasmenylserine | The L-enantiomer of O-phosphoserine. | O-phospho-L-serine |
| poly-o-acetylserine | An acetyl-L-serine where the acetyl group is attached to the side-chain oxygen. It is an intermediate in the biosynthesis of the amino acid cysteine in bacteria. | O-acetyl-L-serine zwitterion; O-acetyl-L-serine |
| proline | Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. | L-proline zwitterion; L-proline |
| propargyl alcohol | A terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1. | prop-2-yn-1-ol |
| pyridoxal | A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxal |
| pyridoxal phosphate | The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. | pyridoxal 5'-phosphate |
| pyridoxamine | A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. | pyridoxamine |
| pyridoxamine dihydrochloride | A hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy. | pyridoxamine dihydrochloride |
| pyridoxamine phosphate | A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. | pyridoxamine 5'-phosphate |
| pyridoxine | A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxine |
| pyruvaldehyde | A 2-oxo aldehyde derived from propanal. | methylglyoxal |
| quinaldic acid | A quinolinemonocarboxylic acid having the carboxy group at the 2-position. | quinaldic acid |
| racemethionine | A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. | methionine zwitterion; methionine |
| raffinose | A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively. | raffinose |
| s-adenosylmethionine | A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. | S-adenosyl-L-methionine zwitterion; S-adenosyl-L-methionine |
| saccharopine | The N(6)-(1,3-dicarboxypropan-1-yl) derivative of L-lysine. | L-saccharopine |
| serine | The L-enantiomer of serine. | L-serine zwitterion; L-serine |
| shikimic acid | A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid substituted by hydroxy groups at positions 3, 4 and 5 (the 3R,4S,5R stereoisomer). It is an intermediate metabolite in plants and microorganisms. | shikimic acid |
| sorbitol | The D-enantiomer of glucitol (also known as D-sorbitol). | D-glucitol |
| squalene | A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. | squalene |
| sucrose | A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose. | sucrose |
| taurine | An amino sulfonic acid that is the 2-amino derivative of ethanesulfonic acid. It is a naturally occurring amino acid derived from methionine and cysteine metabolism. An abundant component of fish- and meat-based foods, it has been used as an oral supplement in the treatment of disorders such as cystic fibrosis and hypertension. | taurine zwitterion; taurine |
| thiamine | A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively. | thiamine(1+) |
| thiamine pyrophosphate | Trianion of thiamine(1+) diphosphate arising from deprotonation of the four OH groups of the triphosphate. | thiamine(1+) triphosphate(4-) |
| threonine | An optically active form of threonine having L-configuration. | L-threonine zwitterion; L-threonine |
| tocotrienol, delta | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2. | delta-tocotrienol |
| toxopyrimidine | An aminopyrimidine that is pyrimidine in which the hydrogens at positions 2, 4, and 5 are replaced by methyl, amino, and hydroxymethyl substituents, respectively. | 4-amino-5-hydroxymethyl-2-methylpyrimidine |
| trehalose | A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon. | alpha,alpha-trehalose |
| tryptophan | The L-enantiomer of tryptophan. | L-tryptophan zwitterion; L-tryptophan |
| tryptophol | An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2. | tryptophol |
| ubiquinone 6 | A ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2. | ubiquinone-6 |
| uracil | A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. | uracil |
| urea | A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). | carbamimidic acid; urea |
| ureidosuccinic acid | An N-carbamoylamino acid that is aspartic acid with one of its amino hydrogens replaced by a carbamoyl group. | N-carbamoylaspartic acid |
| uridine diphosphate | A nucleoside 5'-diphosphate(3-) arising from deprotonation of the diphosphate OH groups of uridine 5'-diphosphate (UDP); major species at pH 7.3. | UDP(3-) |
| valine | The L-enantiomer of valine. | L-valine zwitterion; L-valine |
| xanthine | An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated. | 7H-xanthine; 9H-xanthine |
| xylulose | The D-enantiomer of xylulose. | D-xylulose |
| zymosterol | | zymosterol |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 20.7726 | 1 | 5 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 14.2343 | 2 | 3 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 28.6841 | 4 | 5 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 21.1270 | 1 | 8 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 26.9102 | 1 | 10 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 0.3162 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 17.9596 | 10 | 41 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 26.1826 | 2 | 10 |
| arylsulfatase A | Homo sapiens (human) | Potency | 4.5008 | 1 | 5 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.8188 | 4 | 5 |
| Ataxin-2 | Homo sapiens (human) | Potency | 26.3270 | 1 | 4 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 2.6514 | 1 | 4 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 26.3270 | 1 | 4 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 10.0281 | 2 | 10 |
| BRCA1 | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 36.7872 | 1 | 6 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 52.1285 | 1 | 2 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 76.6697 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 52.1285 | 1 | 2 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 76.6697 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 40.6943 | 2 | 6 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 31.1332 | 1 | 10 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 8.5905 | 1 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 0.6038 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 28.1193 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 44.5990 | 1 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 22.7374 | 1 | 14 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 27.7639 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 62.7012 | 1 | 3 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 28.1193 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 40.5965 | 2 | 6 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 30.4620 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 13.4504 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 20.0162 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 0.7943 | 2 | 4 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 14.4027 | 1 | 7 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 8.0575 | 1 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 4.1092 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 68.0968 | 1 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 26.4147 | 1 | 7 |
| endonuclease IV | Escherichia coli | Potency | 7.2334 | 1 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 17.5732 | 11 | 44 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 36.3022 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 27.7429 | 8 | 37 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 12.9758 | 1 | 18 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 0.2179 | 4 | 5 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 45.9956 | 3 | 5 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 26.4162 | 1 | 4 |
| G | Vesicular stomatitis virus | Potency | 13.4504 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| GALC protein | Homo sapiens (human) | Potency | 0.5623 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 0.7943 | 1 | 2 |
| geminin | Homo sapiens (human) | Potency | 7.2662 | 2 | 15 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 27.2816 | 2 | 26 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 17.5855 | 2 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 11.9125 | 2 | 4 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 26.3498 | 4 | 12 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 22.3073 | 1 | 4 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 30.1718 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 28.2124 | 2 | 7 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 34.1775 | 1 | 6 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 31.3335 | 2 | 6 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 51.4118 | 1 | 7 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 13.4504 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 29.5617 | 2 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| IDH1 | Homo sapiens (human) | Potency | 23.4284 | 1 | 3 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 62.0785 | 2 | 3 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 13.4504 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 2.5109 | 2 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 13.4504 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 8.3394 | 2 | 12 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 11.6399 | 1 | 5 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 46.4553 | 2 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 35.9351 | 2 | 3 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.5579 | 2 | 5 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 0.1585 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 37.3041 | 4 | 22 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 28.0383 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 42.1635 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 35.4813 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 29.2759 | 3 | 15 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 1.8356 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 72.3342 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 3.4300 | 1 | 4 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 36.4505 | 4 | 9 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 36.7225 | 4 | 8 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 64.8188 | 1 | 8 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 27.4150 | 1 | 7 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 52.2758 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 41.8692 | 2 | 5 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 125.8920 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 11.9564 | 2 | 18 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 6.4320 | 1 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 32.9527 | 3 | 24 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 33.4807 | 2 | 16 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 21.9408 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 21.9408 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 0.1122 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 62.0785 | 2 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 32.4681 | 1 | 3 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 12.7750 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 28.3627 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 11.6023 | 2 | 11 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 29.3969 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 20.5973 | 2 | 8 |
| Thrombopoietin | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 22.1480 | 3 | 12 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 16.4939 | 4 | 5 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 22.2675 | 5 | 25 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 42.6993 | 2 | 2 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 0.5623 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 26.3694 | 2 | 6 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 26.2754 | 2 | 7 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 71.1441 | 1 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 22.3073 | 1 | 4 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 4-hydroxy-tetrahydrodipicolinate synthase | Escherichia coli K-12 | Ki | 16.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | IC50 | 80.2000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 0.0150 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1,511.0050 | 2 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 4,669.0000 | 4 | 4 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 100.0000 | 3 | 8 |
| Adenosine deaminase | Bos taurus (cattle) | Ki | 325.0000 | 1 | 2 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 5.4867 | 2 | 3 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 5.9750 | 4 | 4 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 33.3725 | 3 | 4 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 11.0500 | 2 | 2 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | Ki | 130.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 71.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.6800 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | Ki | 925.0000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | Ki | 30.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 96.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | Ki | 211.2500 | 1 | 4 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 63.0200 | 3 | 5 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Bos taurus (cattle) | IC50 | 80.2033 | 3 | 3 |
| Amino acid transporter | Rattus norvegicus (Norway rat) | IC50 | 1,229.7273 | 6 | 11 |
| Angiotensin-converting enzyme | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Aryl hydrocarbon receptor | Homo sapiens (human) | Ki | 21.6000 | 1 | 1 |
| Asc-type amino acid transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 10.0000 | 1 | 1 |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 2 | 3 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | IC50 | 1.0000 | 1 | 1 |
| Calcium-dependent protein kinase 4 | Plasmodium falciparum 3D7 | IC50 | 1.0000 | 1 | 1 |
| Carbonic anhydrase | Methanosarcina thermophila | Ki | 134,333.3333 | 1 | 3 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 19,524.4944 | 3 | 13 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 27,977.2375 | 1 | 8 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 26,550.5618 | 5 | 15 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 25,341.9889 | 2 | 9 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 360.0000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 0.1757 | 1 | 3 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 470.0000 | 2 | 2 |
| Carnitine O-palmitoyltransferase 1, muscle isoform | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Catechol O-methyltransferase | Homo sapiens (human) | Ki | 5,400.0000 | 1 | 1 |
| Cationic amino acid transporter 3 | Homo sapiens (human) | IC50 | 158.0000 | 1 | 1 |
| Cdk-related protein kinase 6 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase | Escherichia coli | IC50 | 1,200.0000 | 1 | 4 |
| Chain A, ADENOSINE DEAMINASE | Mus musculus (house mouse) | Ki | 0.0000 | 1 | 2 |
| Chain A, AMINOPEPTIDASE | Streptomyces griseus | Ki | 12,550.0000 | 1 | 4 |
| Chain A, Anopheles gambiae adenosine kinase | Anopheles gambiae (African malaria mosquito) | Ki | 0.8600 | 1 | 1 |
| Chain A, Arginase 1 | Rattus norvegicus (Norway rat) | Ki | 3,600.0000 | 1 | 1 |
| Chain A, Cytotoxin L | Paeniclostridium sordellii | IC50 | 30.0000 | 1 | 1 |
| Chain A, Glucosamine 6-phosphate Synthase | Escherichia coli | Ki | 350.0000 | 1 | 1 |
| Chain A, Glutamate carboxypeptidase III | Homo sapiens (human) | Ki | 270.0000 | 1 | 3 |
| Chain A, Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.1710 | 1 | 1 |
| Chain A, Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | Ki | 0.2900 | 1 | 2 |
| Chain A, Glutamate receptor, ionotropic kainate 1 | Homo sapiens (human) | Ki | 0.2900 | 1 | 18 |
| Chain A, Glutamate receptor, ionotropic kainate 3 | Rattus norvegicus (Norway rat) | Ki | 7.4300 | 1 | 1 |
| Chain A, Leucine Aminopeptidase | Bos taurus (cattle) | Ki | 0.0600 | 1 | 1 |
| Chain A, MTA/SAH nucleosidase | Escherichia coli | Ki | 300.0000 | 1 | 1 |
| Chain A, NAD-dependent deacetylase | Thermotoga maritima | IC50 | 1,000.0000 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | Pisum sativum (garden pea) | Ki | 36,600.0000 | 1 | 2 |
| Chain A, Seminal ribonuclease | Bos taurus (cattle) | Ki | 1,046.4000 | 1 | 5 |
| Chain A, Toluene-4-monooxygenase system protein A | Pseudomonas mendocina | Ki | 5.0000 | 1 | 1 |
| Chain A, Uracil-DNA Glycosylase | Thermus thermophilus | Ki | 0.0880 | 1 | 1 |
| Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose | Synechocystis sp. PCC 6803 | Ki | 26,000.0000 | 1 | 1 |
| Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose | Synechocystis sp. PCC 6803 | Ki | 26,000.0000 | 1 | 1 |
| Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose | Synechocystis sp. PCC 6803 | Ki | 26,000.0000 | 1 | 1 |
| Chain B, Seminal ribonuclease | Bos taurus (cattle) | Ki | 1,046.4000 | 1 | 5 |
| Cholinesterase | Equus caballus (horse) | IC50 | 0.0160 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | Ki | 100.0000 | 3 | 8 |
| Coagulation factor VII | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| Coagulation factor XII | Homo sapiens (human) | Ki | 100.0000 | 1 | 6 |
| Cocaine esterase | Homo sapiens (human) | Ki | 100.0000 | 2 | 2 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 6,500.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 2,800.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 80.2000 | 1 | 1 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 1,500.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 3.3000 | 1 | 1 |
| Fibrinogen C domain-containing protein 1 | Homo sapiens (human) | IC50 | 4,000.0000 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 39.0000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | Ki | 137.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0323 | 9 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 2,900.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 0.0332 | 10 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 0.0333 | 9 | 11 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 700.0247 | 3 | 3 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | IC50 | 12.9000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 0.1165 | 2 | 2 |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0292 | 4 | 4 |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | IC50 | 0.0292 | 4 | 4 |
| Glucose transporter | Leishmania mexicana | IC50 | 12.0000 | 1 | 1 |
| Glutamate carboxypeptidase 2 | Homo sapiens (human) | IC50 | 523.0000 | 2 | 2 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
| Glutamate receptor 1 | Homo sapiens (human) | Ki | 495.0000 | 1 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
| Glutamate receptor 2 | Homo sapiens (human) | Ki | 495.0000 | 1 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
| Glutamate receptor 3 | Homo sapiens (human) | Ki | 495.0000 | 1 | 2 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 101.0000 | 1 | 1 |
| Glutamate receptor 4 | Homo sapiens (human) | Ki | 495.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Ki | 495.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 150.7000 | 5 | 6 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 5.4000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 112.5000 | 3 | 4 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 2,965.0000 | 1 | 2 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 61.2000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 54.6000 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5880 | 1 | 1 |
| Guanine deaminase | Homo sapiens (human) | Ki | 1.9600 | 1 | 1 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 4,000.0000 | 2 | 3 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 12.0000 | 1 | 1 |
| High affinity choline transporter 1 | Mus musculus (house mouse) | IC50 | 1.6000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 498.7000 | 1 | 1 |
| Indolethylamine N-methyltransferase | Homo sapiens (human) | Ki | 700.0000 | 1 | 2 |
| Intestinal-type alkaline phosphatase | Bos taurus (cattle) | IC50 | 80.2060 | 5 | 5 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 39.0400 | 3 | 5 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 138.3077 | 3 | 13 |
| Large neutral amino acids transporter small subunit 1 | Rattus norvegicus (Norway rat) | Ki | 55.0000 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 15.8090 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Ki | 6.7150 | 1 | 1 |
| Liver carboxylesterase 1 | Homo sapiens (human) | Ki | 100.0000 | 3 | 8 |
| Liver carboxylesterase 1 | Oryctolagus cuniculus (rabbit) | Ki | 100.0000 | 3 | 8 |
| Low molecular weight phosphotyrosine protein phosphatase | Homo sapiens (human) | Ki | 13.0000 | 1 | 1 |
| Lysine--tRNA ligase | Plasmodium falciparum 3D7 | IC50 | 2.5000 | 1 | 1 |
| Lysine-specific demethylase 4C | Homo sapiens (human) | IC50 | 2,070.0000 | 1 | 1 |
| Mitogen-activated protein kinase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.0000 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Ki | 1,300.0000 | 1 | 1 |
| Monocarboxylate transporter 2 | Rattus norvegicus (Norway rat) | Ki | 300.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 2.2500 | 1 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| NAD-dependent histone deacetylase SIR2 | Saccharomyces cerevisiae S288C | IC50 | 50.0000 | 1 | 1 |
| NAD-dependent protein deacetylase | Schistosoma mansoni | IC50 | 221.5500 | 2 | 2 |
| NAD-dependent protein deacetylase HST2 | Saccharomyces cerevisiae S288C | IC50 | 91.0000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 130.9500 | 12 | 12 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 28.2214 | 14 | 14 |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial | Homo sapiens (human) | IC50 | 78.4571 | 7 | 7 |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens (human) | IC50 | 173.3500 | 4 | 4 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | IC50 | 58.2000 | 3 | 3 |
| NAD(+) hydrolase SARM1 | Homo sapiens (human) | IC50 | 43.8000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-10 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 34.0000 | 2 | 3 |
| Neuronal acetylcholine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 42.2500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 38.7500 | 3 | 4 |
| Neuronal acetylcholine receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-9 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 35.2000 | 4 | 5 |
| Neuronal acetylcholine receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 42.0000 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-4 | Rattus norvegicus (Norway rat) | Ki | 41.5000 | 3 | 4 |
| Neutral amino acid transporter A | Homo sapiens (human) | IC50 | 1,615.0000 | 1 | 4 |
| Neutral amino acid transporter B(0) | Homo sapiens (human) | IC50 | 3,009.2500 | 1 | 4 |
| Nitric oxide synthase, brain | Homo sapiens (human) | Ki | 2,350.0000 | 1 | 2 |
| Nitric oxide synthase, brain | Rattus norvegicus (Norway rat) | Ki | 2,350.0000 | 1 | 2 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 30.6000 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 0.2000 | 1 | 1 |
| P2X purinoceptor 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | IC50 | 1,000.0000 | 1 | 1 |
| Phosphodiesterase | Bos taurus (cattle) | IC50 | 0.1000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 3 |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | IC50 | 187.0070 | 6 | 7 |
| Poly [ADP-ribose] polymerase 2 | Mus musculus (house mouse) | IC50 | 129.5245 | 1 | 2 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 8.1900 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Proline--tRNA ligase | Plasmodium falciparum 3D7 | IC50 | 2.5000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 20,000.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | IC50 | 415.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | Ki | 212.0000 | 1 | 1 |
| Protein kinase domain-containing protein | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.0000 | 1 | 1 |
| Protein mono-ADP-ribosyltransferase PARP15 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 2 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 30,900.0000 | 1 | 6 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Ricin | Ricinus communis (castor bean) | IC50 | 2,250.0000 | 1 | 2 |
| Shiga toxin subunit A | Shigella dysenteriae | IC50 | 11.5000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Homo sapiens (human) | IC50 | 15.8771 | 30 | 57 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sodium- and chloride-dependent creatine transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 1.6000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Homo sapiens (human) | IC50 | 5.2623 | 4 | 5 |
| Sodium- and chloride-dependent GABA transporter 1 | Mus musculus (house mouse) | IC50 | 10.3241 | 5 | 6 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 2.1520 | 5 | 15 |
| Sodium- and chloride-dependent GABA transporter 2 | Homo sapiens (human) | IC50 | 26.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 20.7214 | 3 | 3 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 2.5100 | 2 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Homo sapiens (human) | IC50 | 5.3962 | 4 | 5 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 17.5743 | 3 | 3 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 0.0200 | 1 | 1 |
| Sodium- and chloride-dependent taurine transporter | Homo sapiens (human) | IC50 | 182.0000 | 1 | 2 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 396.6667 | 2 | 3 |
| Solute carrier family 15 member 1 | Rattus norvegicus (Norway rat) | Ki | 2,200.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | Ki | 28.9202 | 1 | 2 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 230.0000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 12.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 55.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 925.0000 | 2 | 2 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 736.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 4,354.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 217.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 804.5000 | 2 | 2 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 646.0000 | 1 | 1 |
| Spermidine synthase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 159.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Cricetulus griseus (Chinese hamster) | IC50 | 281.0000 | 2 | 3 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 500.0000 | 1 | 3 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | IC50 | 19.9526 | 1 | 1 |
| Thymidine kinase 2 | Rattus norvegicus (Norway rat) | Ki | 320.0000 | 1 | 1 |
| Thymidine kinase, cytosolic | Homo sapiens (human) | IC50 | 239.5000 | 2 | 2 |
| Tissue factor | Homo sapiens (human) | Ki | 8,000.0000 | 1 | 1 |
| Trans-sialidase | Trypanosoma cruzi | Ki | 7,300.0000 | 2 | 2 |
| Trehalose-phosphatase | Brugia malayi | Ki | 10,000.0000 | 1 | 1 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Ki | 11,500.0000 | 1 | 1 |
| Uracil nucleotide/cysteinyl leukotriene receptor | Homo sapiens (human) | IC50 | 30.0000 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 6,470.0000 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 6,470.0000 | 1 | 1 |
| Vesicular glutamate transporter 3 | Rattus norvegicus (Norway rat) | Ki | 1,300.0000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Mus musculus (house mouse) | Ki | 0.9786 | 1 | 2 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 43.2500 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | Escherichia coli K-12 | Kd | 38.0000 | 1 | 1 |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Burkholderia pseudomallei K96243 | Kd | 1,000.0000 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | EC50 | 100.0000 | 1 | 1 |
| Alpha-crystallin B chain | Homo sapiens (human) | EC50 | 1.4200 | 1 | 1 |
| Aryl hydrocarbon receptor | Homo sapiens (human) | EC50 | 0.3000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Kd | 450,000.0000 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Kd | 150,000.0000 | 1 | 1 |
| Chain A, 2,2-dialkylglycine decarboxylase | Burkholderia cepacia | Kd | 600.0000 | 1 | 1 |
| Chain A, Acetylcholinesterase | Mus musculus (house mouse) | Kd | 930.0000 | 1 | 7 |
| Chain A, ALDOLASE | Oryctolagus cuniculus (rabbit) | Kd | 1.0000 | 1 | 1 |
| Chain A, Avidin | Gallus gallus (chicken) | Kd | 102.6500 | 1 | 4 |
| Chain A, Beta-lactoglobulin | Bos taurus (cattle) | Kd | 92.6000 | 1 | 2 |
| Chain A, Biotin [acetyl-CoA-carboxylase] ligase | Aquifex aeolicus | Kd | 8.3000 | 1 | 2 |
| Chain A, Biotin transporter BioY | Lactococcus cremoris subsp. cremoris MG1363 | Kd | 0.0003 | 1 | 1 |
| Chain A, Carbonic anhydrase 2 | Homo sapiens (human) | Kd | 43.5000 | 1 | 1 |
| Chain A, Choline-binding protein | Bacillus subtilis subsp. subtilis str. JH642 | Kd | 30.5000 | 1 | 1 |
| Chain A, Circular Permutant Of Avidin | Gallus gallus (chicken) | Kd | 0.2400 | 1 | 1 |
| Chain A, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain A, Dutpase | Leishmania major | Kd | 140.0000 | 1 | 3 |
| Chain A, Glucosyltransferase | Legionella pneumophila | Kd | 0.1000 | 1 | 1 |
| Chain A, Glutamine Binding Protein | Escherichia coli | Kd | 0.5000 | 1 | 1 |
| Chain A, Glycine betaine/carnitine/choline-binding protein | Bacillus subtilis | Kd | 28.0000 | 1 | 4 |
| Chain A, HISTIDINE-BINDING PROTEIN | Escherichia coli | Kd | 0.0640 | 1 | 1 |
| Chain A, Ionotropic glutamate receptor bacterial homologue | Nostoc punctiforme PCC 73102 | Kd | 25.0000 | 1 | 1 |
| Chain A, MALTOPORIN | Escherichia coli | Kd | 15,000.0000 | 1 | 1 |
| Chain A, Membrane lipoprotein tmpC | Treponema pallidum | Kd | 0.2100 | 1 | 3 |
| Chain A, Mll3241 protein | Mesorhizobium loti | Kd | 0.1070 | 1 | 1 |
| Chain A, Mll3241 protein | unidentified | Kd | 205.1000 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | Homo sapiens (human) | Kd | 180.0000 | 1 | 13 |
| Chain A, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | Homo sapiens (human) | Kd | 3.6000 | 1 | 1 |
| Chain A, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Homo sapiens (human) | Kd | 0.8300 | 1 | 1 |
| Chain A, PRKG1 protein | Homo sapiens (human) | Kd | 0.0270 | 1 | 2 |
| Chain A, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN | Sinorhizobium meliloti | Kd | 2.3000 | 1 | 2 |
| Chain A, rhizavidin | Rhizobium etli CFN 42 | Kd | 0.2150 | 1 | 1 |
| Chain A, Ribosome-inactivating protein 3 | Zea mays | Kd | 0.0063 | 1 | 1 |
| Chain A, Ribosome-inactivating protein alpha-trichosanthin | Trichosanthes kirilowii | Kd | 260.0000 | 1 | 1 |
| Chain A, Ricin A chain | Ricinus communis (castor bean) | Kd | 700.0000 | 1 | 1 |
| Chain A, Shikimate kinase | Mycobacterium tuberculosis | Kd | 44.0000 | 1 | 1 |
| Chain A, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 15 |
| Chain A, Streptavidin Complex With Biotin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Chain A, Tamavidin2 | Pleurotus cornucopiae (cornucopia mushroom) | Kd | 0.0870 | 1 | 1 |
| Chain A, ThiT | Lactococcus cremoris subsp. cremoris NZ9000 | Kd | 0.0001 | 1 | 1 |
| Chain A, Toxin A | Clostridioides difficile | Kd | 11.4000 | 1 | 1 |
| Chain A, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Chain A, Udp-n-acetylglucosamine--peptide N-acetylglucosaminyl Transferase 110 Kda Subunit | Homo sapiens (human) | Kd | 0.5400 | 1 | 1 |
| Chain A, Udp-n-acetylglucosamine--peptide N-acetylglucosaminyltrans Ferase 110 Kda Subunit | Homo sapiens (human) | Kd | 0.5400 | 1 | 1 |
| Chain A, Xenavidin | Xenopus tropicalis (tropical clawed frog) | Kd | 0.0000 | 1 | 1 |
| Chain A, ykoF | Bacillus subtilis | Kd | 10.0000 | 1 | 1 |
| Chain B, Avidin | Gallus gallus (chicken) | Kd | 205.0000 | 1 | 1 |
| Chain B, Circular Permutant Of Avidin | Gallus gallus (chicken) | Kd | 0.2400 | 1 | 1 |
| Chain B, Dutpase | Leishmania major | Kd | 140.0000 | 1 | 2 |
| Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | Homo sapiens (human) | Kd | 110,000.0000 | 1 | 1 |
| Chain B, Exotoxin A | Pseudomonas aeruginosa | Kd | 59.5667 | 1 | 9 |
| Chain B, MALTOPORIN | Escherichia coli | Kd | 15,000.0000 | 1 | 1 |
| Chain B, Protein (streptavidin) | Streptomyces avidinii | Kd | 0.0002 | 1 | 1 |
| Chain B, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 4 |
| Chain B, Tamavidin2 | Pleurotus cornucopiae (cornucopia mushroom) | Kd | 0.0870 | 1 | 1 |
| Chain B, tryptophanyl-tRNA synthetase | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain B, ykoF | Bacillus subtilis | Kd | 10.0000 | 1 | 1 |
| Chain C, Tryptophanyl-tRNA synthetase II | Deinococcus radiodurans | Kd | 30.0000 | 1 | 1 |
| Chain D, Circularly Permuted Core-streptavidin E51/a46 | Streptomyces avidinii | Kd | 0.0439 | 1 | 1 |
| Chain D, Core-streptavidin | Streptomyces avidinii | Kd | 0.0300 | 1 | 16 |
| Chain D, Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 9 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | Salmonella enterica subsp. enterica serovar Typhimurium | Kd | 0.5000 | 1 | 3 |
| Chain K, Trp Rna-binding Attenuation Protein | Geobacillus stearothermophilus | Kd | 7.5000 | 1 | 1 |
| Dihydrofolate reductase | Escherichia coli K-12 | Kd | 0.2200 | 3 | 3 |
| DNA polymerase subunit gamma-1 | Homo sapiens (human) | Kd | 0.8000 | 1 | 1 |
| G protein-coupled receptor GPR35 | Rattus norvegicus (Norway rat) | EC50 | 66.0000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | EC50 | 199.8000 | 9 | 9 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 20.7620 | 9 | 13 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | EC50 | 6.1500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | EC50 | 10.1514 | 6 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | EC50 | 8.7818 | 6 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | EC50 | 16.0009 | 5 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | EC50 | 7.0091 | 5 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | EC50 | 10.0225 | 4 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | EC50 | 24.8496 | 4 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | EC50 | 5.3824 | 13 | 22 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | EC50 | 2.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | EC50 | 26.7878 | 9 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | EC50 | 13.6289 | 17 | 27 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | EC50 | 2.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | EC50 | 0.5275 | 6 | 9 |
| Gamma-aminobutyric acid receptor subunit rho-1 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-2 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | Homo sapiens (human) | Kd | 1.7000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | EC50 | 1.1150 | 2 | 2 |
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | EC50 | 0.5300 | 1 | 1 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 300.0000 | 1 | 1 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | EC50 | 500.0000 | 1 | 1 |
| Histidine triad nucleotide-binding protein 1 | Mus musculus (house mouse) | Kd | 1,150.0000 | 2 | 2 |
| Histidine-binding periplasmic protein | Escherichia coli K-12 | Kd | 0.1140 | 1 | 1 |
| Hsf1 protein | Mus musculus (house mouse) | EC50 | 195.0000 | 1 | 1 |
| insulin-degrading enzyme isoform 1 | Homo sapiens (human) | EC50 | 2.4495 | 2 | 2 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | EC50 | 1.1500 | 2 | 2 |
| Metabotropic glutamate receptor 4 | Rattus norvegicus (Norway rat) | EC50 | 52.0000 | 2 | 2 |
| Metabotropic glutamate receptor 6 | Rattus norvegicus (Norway rat) | EC50 | 2.7000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | EC50 | 200.0000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Rattus norvegicus (Norway rat) | EC50 | 160.0000 | 1 | 1 |
| Methylosome protein 50 | Homo sapiens (human) | Kd | 0.6610 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | EC50 | 0.1100 | 1 | 1 |
| Olfactory receptor 51E2 | Homo sapiens (human) | EC50 | 0.0078 | 1 | 3 |
| Olfactory receptor class A-like protein 1 | Danio rerio (zebrafish) | EC50 | 30.5000 | 1 | 1 |
| P2X purinoceptor 1 | Rattus norvegicus (Norway rat) | EC50 | 3.0000 | 1 | 1 |
| P2X purinoceptor 2 | Homo sapiens (human) | EC50 | 39.5000 | 1 | 1 |
| P2X purinoceptor 4 | Rattus norvegicus (Norway rat) | EC50 | 219.0000 | 1 | 1 |
| PA-I galactophilic lectin | Pseudomonas aeruginosa PAO1 | Kd | 32.0000 | 1 | 1 |
| Platelet glycoprotein VI | Homo sapiens (human) | Kd | 0.0411 | 1 | 1 |
| Protein arginine N-methyltransferase 5 | Homo sapiens (human) | Kd | 0.6610 | 1 | 1 |
| Purine nucleoside phosphorylase | Bos taurus (cattle) | Kd | 0.9350 | 4 | 4 |
| Pyruvate kinase PKM | Homo sapiens (human) | EC50 | 1,300.0000 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | Kd | 3.1250 | 3 | 4 |
| Sterol O-acyltransferase 1 | Mus musculus (house mouse) | EC50 | 14.3000 | 1 | 1 |
| Streptavidin | Streptomyces avidinii | Kd | 0.0000 | 1 | 1 |
| Thiamine transporter ThiT | Lactococcus cremoris subsp. cremoris MG1363 | Kd | 2.4687 | 7 | 7 |
| Thiamine-binding periplasmic protein | Escherichia coli K-12 | Kd | 0.0038 | 1 | 1 |
| Transketolase | Homo sapiens (human) | Kd | 6,800.0000 | 1 | 1 |
| Trp operon repressor | Escherichia coli K-12 | Kd | 23.3000 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 50,000.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Kd | 1,000.0000 | 1 | 1 |
| UDP-3-O-acyl-N-acetylglucosamine deacetylase | Aquifex aeolicus VF5 | Kd | 100.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 14-alpha sterol demethylase | Aspergillus fumigatus | Ks | 5.8500 | 2 | 2 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | Km | 1,950.0000 | 2 | 2 |
| 4-aminobutyrate aminotransferase, mitochondrial | Sus scrofa (pig) | Km | 1,875.0000 | 4 | 4 |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 113.0000 | 1 | 1 |
| 5-methylthioadenosine/S-adenosylhomocysteine deaminase | Thermotoga maritima MSB8 | Km | 44.0000 | 1 | 1 |
| AAA family ATPase | Staphylococcus aureus | Km | 21.5667 | 2 | 3 |
| Adenosine deaminase | Bos taurus (cattle) | Km | 31.0000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 17.9710 | 1 | 3 |
| Adenosine receptor A2a | Homo sapiens (human) | Affinity constant | 10.0000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 17.9710 | 1 | 6 |
| Adenosine receptor A2b | Homo sapiens (human) | Affinity constant | 10.0000 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | Km | 2.5000 | 1 | 1 |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | Km | 1.9000 | 1 | 1 |
| CAD protein | Homo sapiens (human) | Km | 50.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 19.5750 | 1 | 4 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 55.0000 | 1 | 4 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 53.2250 | 1 | 4 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 86.0000 | 2 | 8 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 41.2500 | 1 | 4 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 26.2750 | 1 | 4 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Activity | 0.0300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 13.1057 | 17 | 54 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ka | 22.4975 | 3 | 8 |
| Carbonic anhydrase 13 | Homo sapiens (human) | KA | 0.4067 | 1 | 3 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 6.6480 | 2 | 5 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 4.9438 | 3 | 8 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 23.2750 | 1 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Activity | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | KA | 26.1115 | 19 | 62 |
| Carbonic anhydrase 3 | Homo sapiens (human) | KA | 23.0450 | 4 | 12 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 39.0000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | KA | 22.5857 | 5 | 14 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 3.0938 | 3 | 8 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 4.1188 | 3 | 8 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 14.6277 | 4 | 13 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 17.3362 | 3 | 8 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 17.8800 | 4 | 9 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 22.7217 | 1 | 6 |
| Carnitine O-acetyltransferase | Homo sapiens (human) | Km | 300.0000 | 1 | 1 |
| Choline O-acetyltransferase | Rattus norvegicus (Norway rat) | Km | 290.0000 | 1 | 1 |
| Cytidine deaminase | Homo sapiens (human) | Km | 40.5000 | 1 | 2 |
| Deoxycytidine kinase | Rattus norvegicus (Norway rat) | IC | 10,000.0000 | 1 | 1 |
| Deoxycytidine kinase | Homo sapiens (human) | Km | 44.5500 | 5 | 8 |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | Km | 4.2000 | 1 | 1 |
| Folylpolyglutamate synthase, mitochondrial | Mus musculus (house mouse) | Km | 3,550,004.0000 | 2 | 2 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | ED50 | 250.0000 | 1 | 1 |
| General amino-acid permease GAP1 | Saccharomyces cerevisiae S288C | Km | 37.0000 | 1 | 1 |
| Glutamate 5-kinase | Escherichia coli K-12 | I0.5 | 2.5000 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Kb | 137.0000 | 2 | 2 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | Kb | 89.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 17.5150 | 1 | 4 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Kb | 154.0000 | 3 | 3 |
| Guanine deaminase | Homo sapiens (human) | Km | 11.2100 | 1 | 1 |
| Histidinol dehydrogenase | Brucella suis 1330 | Km | 12.0000 | 1 | 1 |
| Hypoxanthine-guanine phosphoribosyltransferase | Homo sapiens (human) | Km | 1.9000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Km | 15.0000 | 1 | 1 |
| Kynureninase | Homo sapiens (human) | Km | 400.8000 | 5 | 5 |
| Lanosterol 14-alpha demethylase | Candida albicans SC5314 | Km | 7.4000 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | Km | 30.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | Km | 12.6000 | 2 | 2 |
| Monocarboxylate transporter 1 | Rattus norvegicus (Norway rat) | Km | 1,250.0000 | 1 | 1 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 5,370.0000 | 1 | 2 |
| Monocarboxylate transporter 4 | Homo sapiens (human) | Km | 113,000.0000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | Km | 9.6900 | 1 | 1 |
| Multidrug resistance-associated protein 5 | Homo sapiens (human) | Km | 2.1000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 4.1725 | 1 | 4 |
| Probable deoxycytidylate deaminase | Caenorhabditis elegans | Km | 38.0000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | pKi | 2,000.0000 | 1 | 1 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Km | 395.0000 | 2 | 2 |
| Purine nucleoside phosphorylase | Bos taurus (cattle) | Kieq | 4.0000 | 1 | 1 |
| Pyridoxal kinase | Homo sapiens (human) | Km | 66.3000 | 1 | 3 |
| Receptor-type tyrosine-protein phosphatase beta | Homo sapiens (human) | Kis | 780.4433 | 2 | 3 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | Km | 0.5400 | 1 | 1 |
| S-methyl-5'-thioadenosine phosphorylase | Homo sapiens (human) | Km | 38.5333 | 2 | 3 |
| SLC16A10 protein | Homo sapiens (human) | Km | 596.3500 | 1 | 2 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | Km | 42.0000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Km | 514.0000 | 4 | 4 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Activity | 1,987.0000 | 1 | 2 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Km | 167.3333 | 3 | 3 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Km | 1,015.0000 | 3 | 3 |
| Solute carrier family 22 member 5 | Homo sapiens (human) | Km | 8.5000 | 1 | 1 |
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | Km | 0.0619 | 1 | 1 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | Km | 3.8000 | 1 | 1 |
| Thymidine kinase, cytosolic | Homo sapiens (human) | ID50 | 566.6667 | 1 | 3 |
| Thymidine phosphorylase | Homo sapiens (human) | Km | 559.0000 | 1 | 1 |
| Tryprostatin B synthase | Aspergillus fumigatus Af293 | Km | 820.0000 | 1 | 1 |
| Tryptophan 2,3-dioxygenase | Homo sapiens (human) | Km | 167.0000 | 1 | 1 |
| Uridine-cytidine kinase 1 | Homo sapiens (human) | Km | 131.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Km | 21.4000 | 1 | 1 |